Defined three-dimensional microenvironments boost induction of pluripotency von Caiazzo, Massimiliano, Okawa, Yuya, Ranga, Adrian, Piersigilli, Alessandra, Tabata, Yoji, Lutolf, Matthias P.

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Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer von Sharma, Sai Kiran, Pourat, Jacob, Abdel-Atti, Dalya, Carlin, Sean D, Piersigilli, Alessandra, Bankovich, Alexander J, Gardner, Eric E, Hamdy, Omar, Isse, Kumiko, Bheddah, Sheila, Sandoval, Joseph, Cunanan, Kristen M, Johansen, Eric B, Allaj, Viola, Sisodiya, Vikram, Liu, David, Zeglis, Brian M, Rudin, Charles M, Dylla, Scott J, Poirier, John T, Lewis, Jason S

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Neutrophils and Snail Orchestrate the Establishment of a Pro-tumor Microenvironment in Lung Cancer von Faget, Julien, Groeneveld, Svenja, Boivin, Gael, Sankar, Martial, Zangger, Nadine, Garcia, Miguel, Guex, Nicolas, Zlobec, Inti, Steiner, Loïc, Piersigilli, Alessandra, Xenarios, Ioannis, Meylan, Etienne

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The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation von Zaiss, Mario M., Rapin, Alexis, Lebon, Luc, Dubey, Lalit Kumar, Mosconi, Ilaria, Sarter, Kerstin, Piersigilli, Alessandra, Menin, Laure, Walker, Alan W., Rougemont, Jacques, Paerewijck, Oonagh, Geldhof, Peter, McCoy, Kathleen D., Macpherson, Andrew J., Croese, John, Giacomin, Paul R., Loukas, Alex, Junt, Tobias, Marsland, Benjamin J., Harris, Nicola L.

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Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice von Gariani, Karim, Menzies, Keir J., Ryu, Dongryeol, Wegner, Casey J., Wang, Xu, Ropelle, Eduardo R., Moullan, Norman, Zhang, Hongbo, Perino, Alessia, Lemos, Vera, Kim, Bohkyung, Park, Young‐Ki, Piersigilli, Alessandra, Pham, Tho X., Yang, Yue, Ku, Chai Siah, Koo, Sung I., Fomitchova, Anna, Cantó, Carlos, Schoonjans, Kristina, Sauve, Anthony A., Lee, Ji‐Young, Auwerx, Johan

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SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis von Lo Sasso, Giuseppe, Menzies, Keir Joe, Mottis, Adrienne, Piersigilli, Alessandra, Perino, Alessia, Yamamoto, Hiroyasu, Schoonjans, Kristina, Auwerx, Johan

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Context-dependent roles of MDMX (MDM4) and MDM2 in breast cancer proliferation and circulating tumor cells von Gao, Chong, Xiao, Gu, Piersigilli, Alessandra, Gou, Jiangtao, Ogunwobi, Olorunseun, Bargonetti, Jill

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ALS/FTD mutant CHCHD10 mice reveal a tissue-specific toxic gain-of-function and mitochondrial stress response von Anderson, Corey J., Bredvik, Kirsten, Burstein, Suzanne R., Davis, Crystal, Meadows, Samantha M., Dash, Jalia, Case, Laure, Milner, Teresa A., Kawamata, Hibiki, Zuberi, Aamir, Piersigilli, Alessandra, Lutz, Cathleen, Manfredi, Giovanni

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CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome von Bürgi, Jérôme, Kunz, Béatrice, Abrami, Laurence, Deuquet, Julie, Piersigilli, Alessandra, Scholl-Bürgi, Sabine, Lausch, Ekkehart, Unger, Sheila, Superti-Furga, Andrea, Bonaldo, Paolo, van der Goot, F. Gisou

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Dissecting abdominal aortic aneurysm in Ang II-infused mice: suprarenal branch ruptures and apparent luminal dilatation von Trachet, Bram, Fraga-Silva, Rodrigo A, Piersigilli, Alessandra, Tedgui, Alain, Sordet-Dessimoz, Jessica, Astolfo, Alberto, Van der Donckt, Carole, Modregger, Peter, Stampanoni, Marco F M, Segers, Patrick, Stergiopulos, Nikolaos

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Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer von Lo Sasso, Giuseppe, Ryu, Dongryeol, Mouchiroud, Laurent, Fernando, Samodha C, Anderson, Christopher L, Katsyuba, Elena, Piersigilli, Alessandra, Hottiger, Michael O, Schoonjans, Kristina, Auwerx, Johan

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Increased Myeloid Cell Production and Lung Bacterial Clearance in Mice Exposed to Cigarette Smoke von Basilico, Paola, Cremona, Tiziana P, Oevermann, Anna, Piersigilli, Alessandra, Benarafa, Charaf

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Theranostic pretargeted radioimmunotherapy of internalizing solid tumor antigens in human tumor xenografts in mice: Curative treatment of HER2-positive breast carcinoma von Cheal, Sarah M, Xu, Hong, Guo, Hong-Fen, Patel, Mitesh, Punzalan, Blesida, Fung, Edward K, Lee, Sang-Gyu, Bell, Meghan, Singh, Manisha, Jungbluth, Achim A, Zanzonico, Pat B, Piersigilli, Alessandra, Larson, Steven M, Cheung, Nai-Kong V

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The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease von Gerber, Hermeto, Mosser, Sebastien, Boury-Jamot, Benjamin, Stumpe, Michael, Piersigilli, Alessandra, Goepfert, Christine, Dengjel, Joern, Albrecht, Urs, Magara, Fulvio, Fraering, Patrick C

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Anti-ceramide single-chain variable fragment mitigates radiation GI syndrome mortality independent of DNA repair von Rotolo, Jimmy A., Fong, Chii Shyang, Bodo, Sahra, Nagesh, Prashanth Kb, Fuller, John, Sharma, Thivashnee, Piersigilli, Alessandra, Zhang, Zhigang, Fuks, Zvi, Singh, Vijay K., Kolesnick, Richard

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TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models von Hackett, Christopher S, Hirschhorn, Daniel, Tang, Meixian S, Purdon, Terence J, Marouf, Yacine, Piersigilli, Alessandra, Agaram, Narasimhan P, Liu, Cailian, Schad, Sara E, de Stanchina, Elisa, Rafiq, Sarwish, Monette, Sebastien, Wolchok, Jedd D, Merghoub, Taha, Brentjens, Renier J

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Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development von Ataca, Dalya, Caikovski, Marian, Piersigilli, Alessandra, Moulin, Alexandre, Benarafa, Charaf, Earp, Sarah E, Guri, Yakir, Kostic, Corinne, Arsenijevic, Yvan, Soininen, Raija, Apte, Suneel S, Brisken, Cathrin

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CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade von Giavridis, Theodoros, van der Stegen, Sjoukje J. C., Eyquem, Justin, Hamieh, Mohamad, Piersigilli, Alessandra, Sadelain, Michel

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Senolytic CAR T cells reverse senescence-associated pathologies von Amor, Corina, Feucht, Judith, Leibold, Josef, Ho, Yu-Jui, Zhu, Changyu, Alonso-Curbelo, Direna, Mansilla-Soto, Jorge, Boyer, Jacob A., Li, Xiang, Giavridis, Theodoros, Kulick, Amanda, Houlihan, Shauna, Peerschke, Ellinor, Friedman, Scott L., Ponomarev, Vladimir, Piersigilli, Alessandra, Sadelain, Michel, Lowe, Scott W.

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An electrospun macrodevice for durable encapsulation of human cells with consistent secretion of therapeutic antibodies von Imaichi-Kobayashi, Sachiko, Kassab, Rayan, Piersigilli, Alessandra, Robertson, Robbie, Leonard, Christopher, Long, Nathaniel, Dean, Brenda, Phaneuf, Matthew, Ling, Vincent

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