Tumor immune profiling predicts response to anti-PD-1 therapy in human melanoma von Daud, Adil I, Loo, Kimberly, Pauli, Mariela L, Sanchez-Rodriguez, Robert, Sandoval, Priscila Munoz, Taravati, Keyon, Tsai, Katy, Nosrati, Adi, Nardo, Lorenzo, Alvarado, Michael D, Algazi, Alain P, Pampaloni, Miguel H, Lobach, Iryna V, Hwang, Jimmy, Pierce, Robert H, Gratz, Iris K, Krummel, Matthew F, Rosenblum, Michael D

Volltext

Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma von Phillips, Darci, Matusiak, Magdalena, Gutierrez, Belén Rivero, Bhate, Salil S., Barlow, Graham L., Jiang, Sizun, Demeter, Janos, Smythe, Kimberly S., Pierce, Robert H., Fling, Steven P., Ramchurren, Nirasha, Cheever, Martin A., Goltsev, Yury, West, Robert B., Khodadoust, Michael S., Kim, Youn H., Schürch, Christian M., Nolan, Garry P.

Volltext

Intratumoral Delivery of Plasmid IL12 Via Electroporation Leads to Regression of Injected and Noninjected Tumors in Merkel Cell Carcinoma von Bhatia, Shailender, Longino, Natalie V, Miller, Natalie J, Kulikauskas, Rima, Iyer, Jayasri G, Ibrani, Dafina, Blom, Astrid, Byrd, David R, Parvathaneni, Upendra, Twitty, Christopher G, Campbell, Jean S, Le, Mai H, Gargosky, Sharron, Pierce, Robert H, Heller, Richard, Daud, Adil I, Nghiem, Paul

Volltext

Characterization of abscopal effects of intratumoral electroporation-mediated IL-12 gene therapy von Mukhopadhyay, Anandaroop, Wright, Jocelyn, Shirley, Shawna, Canton, David A., Burkart, Christoph, Connolly, Richard J., Campbell, Jean S., Pierce, Robert H.

Volltext

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation von Kleinschek, Melanie A, Boniface, Katia, Sadekova, Svetlana, Grein, Jeff, Murphy, Erin E, Turner, Scott P, Raskin, Lisa, Desai, Bela, Faubion, William A, de Waal Malefyt, Rene, Pierce, Robert H, McClanahan, Terrill, Kastelein, Robert A

Volltext

IL-33 Induces IL-13-Dependent Cutaneous Fibrosis von Rankin, Andrew L, Mumm, John B, Murphy, Erin, Turner, Scott, Yu, Ni, McClanahan, Terrill K, Bourne, Patricia A, Pierce, Robert H, Kastelein, Rob, Pflanz, Stefan

Volltext

Kupffer cell heterogeneity: functional properties of bone marrow–derived and sessile hepatic macrophages von Klein, Ingo, Cornejo, Judith C., Polakos, Noelle K., John, Beena, Wuensch, Sherry A., Topham, David J., Pierce, Robert H., Crispe, Ian Nicholas

Volltext

IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass von Adamopoulos, Iannis E, Tessmer, Marlowe, Chao, Cheng-Chi, Adda, Sarvesh, Gorman, Dan, Petro, Mary, Chou, Chuan-Chu, Pierce, Robert H, Yao, Wei, Lane, Nancy E, Laface, Drake, Bowman, Edward P

Volltext

TLR-dependent cross talk between human Kupffer cells and NK cells von Tu, Zhengkun, Bozorgzadeh, Adel, Pierce, Robert H, Kurtis, Jonathan, Crispe, I Nicholas, Orloff, Mark S

Volltext

Enhanced and sustained biodistribution of HIV-1 neutralizing antibody VRC01LS in human genital and rectal mucosa von Lemos, Maria P., Astronomo, Rena D., Huang, Yunda, Narpala, Sandeep, Prabhakaran, Madhu, Mann, Philipp, Paez, Carmen A., Lu, Yiwen, Mize, Gregory J., Glantz, Hayley, Westerberg, Katharine, Colegrove, Hunter, Smythe, Kimberly S., Lin, Minggang, Pierce, Robert H., Hutter, Julia, Frank, Ian, Mascola, John R., McDermott, Adrian B., Bekker, Linda-Gail, McElrath, M. Juliana

Volltext

Hepatitis C Virus Core Protein Subverts the Antiviral Activities of Human Kupffer Cells von Tu, Zhengkun, Pierce, Robert H, Kurtis, Jonathan, Kuroki, Yoshio, Crispe, I. Nicholas, Orloff, Mark S

Volltext

Interleukin-6 is an important in vivo inhibitor of intestinal epithelial cell death in mice von Jin, Xiaoling, Zimmers, Teresa A, Zhang, Zongxiu, Pierce, Robert H, Koniaris, Leonidas G

Volltext

Effects of HLA single chain trimer design on peptide presentation and stability von Finton, Kathryn A K, Rupert, Peter B, Friend, Della J, Dinca, Ana, Lovelace, Erica S, Buerger, Matthew, Rusnac, Domnita V, Foote-McNabb, Ulysses, Chour, William, Heath, James R, Campbell, Jean S, Pierce, Robert H, Strong, Roland K

Volltext

Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice von Cheung, Ricky, Shen, Fran, Phillips, Joseph H, McGeachy, Mandy J, Cua, Daniel J, Heyworth, Paul G, Pierce, Robert H

Volltext

Genetically engineered macrophages persist in solid tumors and locally deliver therapeutic proteins to activate immune responses von Brempelis, Katherine J, Cowan, Courtney M, Kreuser, Shannon A, Labadie, Kevin P, Prieskorn, Brooke M, Lieberman, Nicole A P, Ene, Chibawanye I, Moyes, Kara W, Chinn, Harrison, DeGolier, Kole R, Matsumoto, Lisa R, Daniel, Sara K, Yokoyama, Jason K, Davis, Amira D, Hoglund, Virginia J, Smythe, Kimberly S, Balcaitis, Stephanie D, Jensen, Michael C, Ellenbogen, Richard G, Campbell, Jean S, Pierce, Robert H, Holland, Eric C, Pillarisetty, Venu G, Crane, Courtney A

Volltext

Conditionally Active, pH-Sensitive Immunoregulatory Antibodies Targeting VISTA and CTLA-4 Lead an Emerging Class of Cancer Therapeutics von Smith, F. Donelson, Pierce, Robert H, Thisted, Thomas, van der Horst, Edward H

Volltext

In-situ tumor vaccination: Bringing the fight to the tumor von Pierce, Robert H, Campbell, Jean S, Pai, Sara I, Brody, Joshua D, Kohrt, Holbrook EK

Volltext

Glutamate Cysteine Ligase Modifier Subunit Deficiency and Gender as Determinants of Acetaminophen-Induced Hepatotoxicity in Mice von McConnachie, Lisa A., Mohar, Isaac, Hudson, Francesca N., Ware, Carol B., Ladiges, Warren C., Fernandez, Carolina, Chatterton-Kirchmeier, Sam, White, Collin C., Pierce, Robert H., Kavanagh, Terrance J.

Volltext

Transcriptional and functional analyses of neoantigen-specific CD4 T cells during a profound response to anti-PD-L1 in metastatic Merkel cell carcinoma von Church, Candice, Pulliam, Thomas, Longino, Natalie, Park, Song Y, Smythe, Kimberly S, Makarov, Vladimir, Riaz, Nadeem, Jing, Lichen, Amezquita, Robert, Campbell, Jean S, Gottardo, Raphael, Pierce, Robert H, Choi, Jaehyuk, Chan, Timothy A, Koelle, David M, Nghiem, Paul

Volltext

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12 von Garris, Christopher S., Arlauckas, Sean P., Kohler, Rainer H., Trefny, Marcel P., Garren, Seth, Piot, Cécile, Engblom, Camilla, Pfirschke, Christina, Siwicki, Marie, Gungabeesoon, Jeremy, Freeman, Gordon J., Warren, Sarah E., Ong, SuFey, Browning, Erica, Twitty, Christopher G., Pierce, Robert H., Le, Mai H., Algazi, Alain P., Daud, Adil I., Pai, Sara I., Zippelius, Alfred, Weissleder, Ralph, Pittet, Mikael J.

Volltext