In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer von Carugo, Alessandro, Genovese, Giannicola, Seth, Sahil, Nezi, Luigi, Rose, Johnathon Lynn, Bossi, Daniela, Cicalese, Angelo, Shah, Parantu Krushnakant, Viale, Andrea, Pettazzoni, Piergiorgio Francesco, Akdemir, Kadir Caner, Bristow, Christopher Aaron, Robinson, Frederick Scott, Tepper, James, Sanchez, Nora, Gupta, Sonal, Estecio, Marcos Roberto, Giuliani, Virginia, Dellino, Gaetano Ivan, Riva, Laura, Yao, Wantong, Di Francesco, Maria Emilia, Green, Tessa, D’Alesio, Carolina, Corti, Denise, Kang, Ya’an, Jones, Philip, Wang, Huamin, Fleming, Jason Bates, Maitra, Anirban, Pelicci, Pier Giuseppe, Chin, Lynda, DePinho, Ronald Anthony, Lanfrancone, Luisa, Heffernan, Timothy Paul, Draetta, Giulio Francesco

Volltext

Myc represses transcription through recruitment of DNA methyltransferase corepressor von Brenner, Carmen, Deplus, Rachel, Didelot, Céline, Loriot, Axelle, Viré, Emmanuelle, De Smet, Charles, Gutierrez, Arantxa, Danovi, Davide, Bernard, David, Boon, Thierry, Giuseppe Pelicci, Pier, Amati, Bruno, Kouzarides, Tony, de Launoit, Yvan, Di Croce, Luciano, Fuks, François

Volltext

Tumor mutational burden quantification from targeted gene panels: major advancements and challenges von Fancello, Laura, Gandini, Sara, Pelicci, Pier Giuseppe, Mazzarella, Luca

Volltext

The Redox Enzyme p66Shc Contributes to Diabetes and Ischemia-Induced Delay in Cutaneous Wound Healing von PAOLO FADINI, Gian, ALBIERO, Mattia, AGOSTINI, Carlo, GIUSEPPE PELICCI, Pier, GIORGIO, Marco, AVOGARO, Angelo, MENEGAZZO, Lisa, BOSCARO, Elisa, PAGNIN, Elisa, IORI, Elisabetta, COSMA, Chiara, LAPOLLA, Annunziata, PENGO, Vittorio, STENDARDO, Massimo

Volltext

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer von Minucci, Saverio, Pelicci, Pier Giuseppe

Volltext

Identification of Novel Potential Predisposing Variants in Familial Acute Myeloid Leukemia von Ronchini, Chiara, Gigli, Federica, Fontanini, Martina, Furgi, Raffaella, Amato, Viviana, Giglio, Fabio, Gregato, Giuliana, Bertolini, Francesco, Rondoni, Michela, Lanza, Francesco, Billio, Atto, Derenzini, Enrico, Tarella, Corrado, Pelicci, Pier Giuseppe, Alcalay, Myriam, Todisco, Elisabetta

Volltext

Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant von COLOMBO, Emanuela, MARTINELLI, Paola, GIUSEPPE PELICCI, Pier, ZAMPONI, Raffaella, SHING, Danielle C, BONETTI, Paola, LUZI, Lucilla, VOLORIO, Sara, BERNARD, Loris, PRUNERI, Giancarlo, ALCALAY, Myriam

Volltext

Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth von Di Malta, Chiara, Siciliano, Diletta, Calcagni, Alessia, Monfregola, Jlenia, Punzi, Simona, Pastore, Nunzia, Eastes, Andrea N., Davis, Oliver, De Cegli, Rossella, Zampelli, Angela, Di Giovannantonio, Luca G., Nusco, Edoardo, Platt, Nick, Guida, Alessandro, Ogmundsdottir, Margret Helga, Lanfrancone, Luisa, Perera, Rushika M., Zoncu, Roberto, Pelicci, Pier Giuseppe, Settembre, Carmine, Ballabio, Andrea

Volltext

Molecular mechanisms of asymmetric divisions in mammary stem cells von Santoro, Angela, Vlachou, Thalia, Carminati, Manuel, Pelicci, Pier Giuseppe, Mapelli, Marina

Volltext

p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling von Memmi, Elisa Maria, Sanarico, Anna Giulia, Giacobbe, Arianna, Peschiaroli, Angelo, Frezza, Valentina, Cicalese, Angelo, Pisati, Federica, Tosoni, Daniela, Zhou, Huiqing, Tonon, Giovanni, Antonov, Alexey, Melino, Gerry, Pelicci, Pier Giuseppe, Bernassola, Francesca

Volltext

NA-Seq: A Discovery Tool for the Analysis of Chromatin Structure and Dynamics during Differentiation von Gargiulo, Gaetano, Levy, Samuel, Bucci, Gabriele, Romanenghi, Mauro, Fornasari, Lorenzo, Beeson, Karen Y., Goldberg, Susanne M., Cesaroni, Matteo, Ballarini, Marco, Santoro, Fabio, Bezman, Natalie, Frigè, Gianmaria, Gregory, Philip D., Holmes, Michael C., Strausberg, Robert L., Pelicci, Pier Giuseppe, Urnov, Fyodor D., Minucci, Saverio

Volltext

Human cord blood (hCB)-CD34+ humanized mice fail to reject human acute myeloid leukemia cells von Tanaskovic, Olga, Verga Falzacappa, Maria Vittoria, Pelicci, Pier Giuseppe

Volltext

Exploiting the tunability of stimulated emission depletion microscopy for super-resolution imaging of nuclear structures von Sarmento, Maria J., Oneto, Michele, Pelicci, Simone, Pesce, Luca, Scipioni, Lorenzo, Faretta, Mario, Furia, Laura, Dellino, Gaetano Ivan, Pelicci, Pier Giuseppe, Bianchini, Paolo, Diaspro, Alberto, Lanzanò, Luca

Volltext

Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations von Dellino, Gaetano Ivan, Palluzzi, Fernando, Chiariello, Andrea Maria, Piccioni, Rossana, Bianco, Simona, Furia, Laura, De Conti, Giulia, Bouwman, Britta A. M., Melloni, Giorgio, Guido, Davide, Giacò, Luciano, Luzi, Lucilla, Cittaro, Davide, Faretta, Mario, Nicodemi, Mario, Crosetto, Nicola, Pelicci, Pier Giuseppe

Volltext

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication von Di Micco, Raffaella, Fumagalli, Marzia, Cicalese, Angelo, Piccinin, Sara, Gasparini, Patrizia, Luise, Chiara, Schurra, Catherine, Garre’, Massimiliano, Giovanni Nuciforo, Paolo, Bensimon, Aaron, Maestro, Roberta, Giuseppe Pelicci, Pier, d’Adda di Fagagna, Fabrizio

Volltext

DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions von Insinga, Alessandra, Cicalese, Angelo, Faretta, Mario, Gallo, Barbara, Albano, Luisa, Ronzoni, Simona, Furia, Laura, Viale, Andrea, Pelicci, Pier Giuseppe

Volltext

The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathway von Martinelli, Paola, Bonetti, Paola, Sironi, Cristina, Pruneri, Giancarlo, Fumagalli, Caterina, Raviele, Paola Rafaniello, Volorio, Sara, Pileri, Stefano, Chiarle, Roberto, McDuff, Fiona Kate Elizabeth, Tusi, Betsabeh Khoramian, Turner, Suzanne D., Inghirami, Giorgio, Pelicci, Pier Giuseppe, Colombo, Emanuela

Volltext

On the epigenetic role of guanosine oxidation von Giorgio, Marco, Dellino, Gaetano Ivan, Gambino, Valentina, Roda, Niccolo’, Pelicci, Pier Giuseppe

Volltext

Regulation of LncRNAs in Melanoma and Their Functional Roles in the Metastatic Process von Melixetian, Marine, Pelicci, Pier Giuseppe, Lanfrancone, Luisa

Volltext

The pro-oxidant adaptor p66SHC promotes B cell mitophagy by disrupting mitochondrial integrity and recruiting LC3-II von Onnis, Anna, Cianfanelli, Valentina, Cassioli, Chiara, Samardzic, Dijana, Pelicci, Pier Giuseppe, Cecconi, Francesco, Baldari, Cosima T

Volltext