Mechanisms of tumor vascular shutdown induced by 5,6‐dimethylxanthenone‐4‐acetic acid (DMXAA): Increased tumor vascular permeability von Zhao, Liangli, Ching, Lai‐Ming, Kestell, Philip, Kelland, Lloyd R., Baguley, Bruce C.

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A rapid LC–MS/MS method for the quantitation of a series of benzonaphthyridine derivatives: Application to in vivo pharmacokinetic and lipophilicity studies in drug development von Lukka, Pradeep B., Paxton, James W., Atwell, Graham J., Kestell, Philip, Baguley, Bruce C.

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Thalidomide Pharmacokinetics and Metabolite Formation in Mice, Rabbits, and Multiple Myeloma Patients von CHUNG, Francisco, JUN LU, PALMER, Brian D, KESTELL, Philip, BROWETT, Peter, BAGULEY, Bruce C, TINGLE, Malcolm, CHING, Lai-Ming

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Development and validation of a liquid chromatography–mass spectrometry (LC–MS) assay for the determination of the anti-cancer agent N-[2-(dimethylamino)ethyl]-2,6-dimethyl-1-oxo-1... von Lukka, Pradeep B., Kestell, Philip, Paxton, James W., Baguley, Bruce C.

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Rat Tumor Response to the Vascular-Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid as Measured by Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Plasma 5-Hydroxyindole... von McPhail, Lesley D., McIntyre, Dominick J.O., Ludwig, Christian, Kestell, Philip, Griffiths, John R., Kelland, Lloyd R., Robinson, Simon P.

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Improvement of the Antitumor Activity of Intraperitoneally and Orally Administered 5,6-Dimethylxanthenone-4-Acetic Acid by Optimal Scheduling von Zhao, Liangli, Ching, Lai-Ming, Kestell, Philip, Baguley, Bruce C

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Contrasting effects of non-starch polysaccharide and resistant starch-based diets on the disposition and excretion of the food carcinogen, 2-amino-3-methylimidazo[4,5- f]quinoline... von Ferguson, Lynnette R, Zhu, Shuotun, Kestell, Philip

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Synthesis and Biological Evaluation of Novel Analogues of the Pan Class I Phosphatidylinositol 3-Kinase (PI3K) Inhibitor 2-(Difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2... von Rewcastle, Gordon W, Gamage, Swarna A, Flanagan, Jack U, Frederick, Raphael, Denny, William A, Baguley, Bruce C, Kestell, Philip, Singh, Ripudaman, Kendall, Jackie D, Marshall, Elaine S, Lill, Claire L, Lee, Woo-Jeong, Kolekar, Sharada, Buchanan, Christina M, Jamieson, Stephen M. F, Shepherd, Peter R

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Determination of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid and its acyl glucuronide in Caco-2 monolayers by liquid chromatography with fluorescence... von Zhou, Shufeng, Feng, Xia, Kestell, Philip, Baguley, Bruce C., Paxton, James W.

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Synthesis and Biological Evaluation of Novel Analogues of the Pan Class I Phosphatidylinositol 3-Kinase (PI3K) Inhibitor 2-(Difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2... von Rewcastle, Gordon W., Gamage, Swarna A., Flanagan, Jack U., Frederick, Raphael, Denny, William A., Baguley, Bruce C., Kestell, Philip, Singh, Ripudaman, Kendall, Jackie D., Marshall, Elaine S., Lill, Claire L., Lee, Woo-Jeong, Kolekar, Sharada, Buchanan, Christina M., Jamieson, Stephen M. F., Shepherd, Peter R.

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Comparison of a homologous series of benzonaphthyridine anti-cancer agents in mice: divergence between tumour and plasma pharmacokinetics von Lukka, Pradeep B., Paxton, James W., Kestell, Philip, Baguley, Bruce C.

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Synthesis and biological evaluation of novel phosphatidylinositol 3-kinase inhibitors: Solubilized 4-substituted benzimidazole analogs of 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl... von Rewcastle, Gordon W., Gamage, Swarna A., Flanagan, Jack U., Kendall, Jackie D., Denny, William A., Baguley, Bruce C., Buchanan, Christina M., Chao, Mindy, Kestell, Philip, Kolekar, Sharada, Lee, Woo-Jeong, Lill, Claire L., Malik, Alisha, Singh, Ripudaman, Jamieson, Stephen M.F., Shepherd, Peter R.

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Metabolism of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in cancer patients undergoing a phase I clinical trial von SCHOFIELD, P. C, ROBERTSON, I. G. C, PAXTON, J. W, MCCRYSTAL, M. R, EVANS, B. D, KESTELL, P, BAGULEY, B. C

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Pharmacokinetics and distribution of SN 28049, a novel DNA binding anticancer agent, in mice von Lukka, Pradeep B, Paxton, James W, Kestell, Philip, Baguley, Bruce C

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Therapeutic reactivation of mutant p53 protein by quinazoline derivatives von Sutherland, Hamish S., Hwang, In Young, Marshall, Elaine S., Lindsay, Brent S., Denny, William A., Gilchrist, Catherine, Joseph, Wayne R., Greenhalgh, Debra, Richardson, Emma, Kestell, Philip, Ding, Angela, Baguley, Bruce C.

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5,6-dimethylxanthenone-4-acetic acid (DMXAA): a new biological response modifier for cancer therapy von SHUFENG ZHOU, KESTELL, Philip, BAGULEY, Bruce C, PAXTON, James W

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Transport of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid and its acyl glucuronide by human intestinal Caco-2 cells von Zhou, Shufeng, Feng, Xia, Kestell, Philip, Paxton, James W., Baguley, Bruce C., Chan, Eli

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Induction of tumour necrosis factor and interferon-γ in cultured murine splenocytes by the antivascular agent DMXAA and its metabolites von Wang, Liang-Chuan S., Reddy, Charu B., Baguley, Bruce C., Kestell, Philip, Sutherland, Rachel, Ching, Lai-Ming

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Enhancement of the action of the antivascular drug 5,6-dimethylxanthenone-4-acetic acid (DMXAA; ASA404) by non-steroidal anti-inflammatory drugs von Wang, L.-C. Steve, Ching, Lai-Ming, Paxton, James W., Kestell, Philip, Sutherland, Rachel, Zhuang, Li, Baguley, Bruce C.

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Preclinical factors influencing the relative contributions of Phase I and II enzymes to the metabolism of the experimental anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid von Zhou, Shufeng, Kestell, Philip, Baguley, Bruce C, Paxton, James W

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