The preclinical natural history of serous ovarian cancer: defining the target for early detection von Brown, Patrick O, Palmer, Chana

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Prospective Observational Study of Breast Cancer Treatment Outcomes for UK Women Aged 18―40 Years at Diagnosis: The POSH Study von COPSON, Ellen, ECCLES, Bryony, JONES, Louise, BLISS, Judith, ECCLES, Diana, MAISHMAN, Tom, GERTY, Sue, STANTON, Louise, CUTRESS, Ramsey I, ALTMAN, Douglas G, DURCAN, Lorraine, SIMMONDS, Peter, LAWRENCE, Gill

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Hazards of cigarettes, smokeless tobacco and waterpipe in a Middle Eastern Population: a Cohort Study of 50 000 individuals from Iran von Etemadi, Arash, Khademi, Hooman, Kamangar, Farin, Freedman, Neal D, Abnet, Christian C, Brennan, Paul, Malekzadeh, Reza

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Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer von Hung, Rayjean J, Ulrich, Cornelia M, Goode, Ellen L, Brhane, Yonathan, Muir, Kenneth, Chan, Andrew T, Marchand, Loic Le, Schildkraut, Joellen, Witte, John S, Eeles, Rosalind, Boffetta, Paolo, Spitz, Margaret R, Poirier, Julia G, Rider, David N, Fridley, Brooke L, Chen, Zhihua, Haiman, Christopher, Schumacher, Fredrick, Easton, Douglas F, Landi, Maria Teresa, Brennan, Paul, Houlston, Richard, Christiani, David C, Field, John K, Bickeböller, Heike, Risch, Angela, Kote-Jarai, Zsofia, Wiklund, Fredrik, Grönberg, Henrik, Chanock, Stephen, Berndt, Sonja I, Kraft, Peter, Lindström, Sara, Al Olama, Ali Amin, Song, Honglin, Phelan, Catherine, Wentzensen, Nicholas, Peters, Ulrike, Slattery, Martha L, Sellers, Thomas A, Casey, Graham, Gruber, Stephen B, Hunter, David J, Amos, Christopher I, Henderson, Brian

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Sex-Specific Genetic Associations for Barrett’s Esophagus and Esophageal Adenocarcinoma von Dong, Jing, Maj, Carlo, Tsavachidis, Spiridon, Ostrom, Quinn T., Gharahkhani, Puya, Anderson, Lesley A., Wu, Anna H., Ye, Weimin, Bernstein, Leslie, Borisov, Oleg, Schröder, Julia, Chow, Wong-Ho, Gammon, Marilie D., Liu, Geoffrey, Caldas, Carlos, Pharoah, Paul D., Risch, Harvey A., May, Andrea, Gerges, Christian, Anders, Mario, Venerito, Marino, Schmidt, Thomas, Izbicki, Jakob R., Hölscher, Arnulf H., Schumacher, Brigitte, Vashist, Yogesh, Neuhaus, Horst, Rösch, Thomas, Knapp, Michael, Krawitz, Peter, Böhmer, Anne, Iyer, Prasad G., Reid, Brian J., Lagergren, Jesper, Shaheen, Nicholas J., Corley, Douglas A., Gockel, Ines, Fitzgerald, Rebecca C., Dong, Jing, Maj, Carlo, Tsavachidis, Spiridon, Ostrom, Quinn T., Gharahkhani, Puya, Anderson, Lesley A., Wu, Anna H., Ye, Weimin, Bernstein, Leslie, Borisov, Oleg, Schröder, Julia, Chow, Wong-Ho, Gammon, Marilie D., Liu, Geoffrey, Caldas, Carlos, Pharoah, Paul D., Risch, Harvey A., May, Andrea, Gerges, Christian, Anders, Mario, Venerito, Marino, Schmidt, Thomas, Izbicki, Jakob R., Hölscher, Arnulf H., Schumacher, Brigitte, Vashist, Yogesh, Neuhaus, Horst, Rösch, Thomas, Knapp, Michael, Krawitz, Peter, Böhmer, Anne, Iyer, Prasad G., Reid, Brian J., Lagergren, Jesper, Shaheen, Nicholas J., Corley, Douglas A., Gockel, Ines, Fitzgerald, Rebecca C., Cook, Michael B., Whiteman, David C., Vaughan, Thomas L., Schumacher, Johannes, Thrift, Aaron P., Cook, Michael B., Whiteman, David C., Vaughan, Thomas L., Schumacher, Johannes, Thrift, Aaron P.

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Most common 'sporadic' cancers have a significant germline genetic component von Lu, Yi, Ek, Weronica E, Whiteman, David, Vaughan, Thomas L, Spurdle, Amanda B, Easton, Douglas F, Pharoah, Paul D, Thompson, Deborah J, Dunning, Alison M, Hayward, Nicholas K, Chenevix-Trench, Georgia, Macgregor, Stuart

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Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers von Zhang, Yan Dora, Hurson, Amber N., Zhang, Haoyu, Choudhury, Parichoy Pal, Easton, Douglas F., Milne, Roger L., Simard, Jacques, Hall, Per, Michailidou, Kyriaki, Dennis, Joe, Schmidt, Marjanka K., Chang-Claude, Jenny, Gharahkhani, Puya, Whiteman, David, Campbell, Peter T., Hoffmeister, Michael, Jenkins, Mark, Peters, Ulrike, Hsu, Li, Gruber, Stephen B., Casey, Graham, Schmit, Stephanie L., O’Mara, Tracy A., Spurdle, Amanda B., Thompson, Deborah J., Tomlinson, Ian, De Vivo, Immaculata, Landi, Maria Teresa, Law, Matthew H., Iles, Mark M., Demenais, Florence, Kumar, Rajiv, MacGregor, Stuart, Bishop, D. Timothy, Ward, Sarah V., Bondy, Melissa L., Houlston, Richard, Wiencke, John K., Melin, Beatrice, Barnholtz-Sloan, Jill, Kinnersley, Ben, Wrensch, Margaret R., Amos, Christopher I., Hung, Rayjean J., Brennan, Paul, McKay, James, Caporaso, Neil E., Berndt, Sonja I., Birmann, Brenda M., Camp, Nicola J., Kraft, Peter, Rothman, Nathaniel, Slager, Susan L., Berchuck, Andrew, Pharoah, Paul D. P., Sellers, Thomas A., Gayther, Simon A., Pearce, Celeste L., Goode, Ellen L., Schildkraut, Joellen M., Moysich, Kirsten B., Amundadottir, Laufey T., Jacobs, Eric J., Klein, Alison P., Petersen, Gloria M., Risch, Harvey A., Stolzenberg-Solomon, Rachel Z., Wolpin, Brian M., Li, Donghui, Eeles, Rosalind A., Haiman, Christopher A., Kote-Jarai, Zsofia, Schumacher, Fredrick R., Al Olama, Ali Amin, Purdue, Mark P., Scelo, Ghislaine, Dalgaard, Marlene D., Greene, Mark H., Grotmol, Tom, Kanetsky, Peter A., McGlynn, Katherine A., Nathanson, Katherine L., Turnbull, Clare, Wiklund, Fredrik, Chanock, Stephen J., Chatterjee, Nilanjan, Garcia-Closas, Montserrat

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An evaluation of the prognostic model PREDICT using the POSH cohort of women aged ⩽40 years at breast cancer diagnosis von Maishman, T, Copson, E, Stanton, L, Gerty, S, Dicks, E, Durcan, L, Wishart, G C, Pharoah, P, Eccles, D

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Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways von Duffy, David L., Zhu, Gu, Li, Xin, Sanna, Marianna, Iles, Mark M., Jacobs, Leonie C., Evans, David M., Yazar, Seyhan, Beesley, Jonathan, Law, Matthew H., Kraft, Peter, Visconti, Alessia, Taylor, John C., Liu, Fan, Wright, Margaret J., Henders, Anjali K., Bowdler, Lisa, Glass, Dan, Ikram, M. Arfan, Uitterlinden, André G., Madden, Pamela A., Heath, Andrew C., Nelson, Elliot C., Green, Adele C., Chanock, Stephen, Barrett, Jennifer H., Brown, Matthew A., Hayward, Nicholas K., MacGregor, Stuart, Sturm, Richard A., Hewitt, Alex W., Kayser, Manfred, Hunter, David J., Newton Bishop, Julia A., Spector, Timothy D., Montgomery, Grant W., Mackey, David A., Smith, George Davey, Nijsten, Tamar E., Bishop, D. Timothy, Bataille, Veronique, Falchi, Mario, Han, Jiali, Martin, Nicholas G.

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Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research von Fitzgerald, Rebecca C, Hardwick, Richard, Huntsman, David, Carneiro, Fatima, Guilford, Parry, Blair, Vanessa, Chung, Daniel C, Norton, Jeff, Ragunath, Krishnadath, Van Krieken, J Han, Dwerryhouse, Sarah, Caldas, Carlos

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Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use von Jiang, Yu, Hughey, Jordan M., Zhan, Xiaowei, Gong, Jian, Batini, Chiara, Liu, MengZhen, Surendran, Praveen, Young, Robin, Nielsen, Sune Fallgaard, Kontto, Jukka, Perola, Markus, Caslake, Muriel, Reily, Dermot F., Vogt, Thomas, Sattar, Naveed, Ford, Ian, Alam, Dewan S., Majumder, Abdulla al Shafi, Di Angelantonio, Emanuele, Chowdhury, Rajiv, Arveiler, Dominique, Blankenberg, Stefan, Veronesi, Giovanni, EPIC-CVD Consortium, Frossard, Philippe, Nordestgaard, Børge Grønne, Saleheen, Danish, Danesh, John, Butterworth, Adam S., Warren, Helen R., Tragante, Vinicius, Altmaier, Elisabeth, Luan, Jian’an, Scott, Robert A., Stirrups, Kathleen, Marouli, Eirini, Karpe, Fredrik, Poulter, Neil, Rolandsson, Olov, Chambers, John C., Kooner, Jaspal S., Wareham, Nicholas J., Renström, Frida, Hallmans, Göran, Marioni, Riccardo E., Corley, Janie, Starr, John M., van der Meer, Peter, Yavas, Ersin, Vaartjes, Ilonca, Asselbergs, Folkert W., Grabe, Hans J., Nauck, Matthias, Pharoah, Paul D.P., Dunning, Alison M., Dennis, Joe G., Tyrrell, Jessica, Mihailov, Evelin, Metspalu, Andres, Palmer, Colin N.A., Hall, Ian P., Strachan, David P., Understanding Society Scientific Group, Munroe, Patricia B., Jansson, Jan-Håkan, Franks, Paul W., Deloukas, Panos, Chou, Yi-Ling, Faul, Jessica D., Hammerschlag, Anke R., Hsu, Chris, Lai, Dongbing, Le, Nhung, Loukola, Anu, Mangino, Massimo, Melbourne, Carl A., Pistis, Giorgio, Qaiser, Beenish, Stringham, Heather, Wetherill, Leah, Bierut, Laura, Chen, Chu, Eaton, Charles B., Iacono, William G., Polderman, Tinca J., Schlessinger, David, Scholte, H. Steven, Smith, Jennifer A., Boehnke, Michael, Cucca, Francesco, David, Sean P., Foroud, Tatiana, Kardia, Sharon L.R., Madden, Pamela, McGue, Matt, Posthuma, Danielle, Spector, Timothy, Stram, Daniel, Kaprio, Jaakko, Vrieze, Scott

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Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes von Zhang, Tongwu, Choi, Jiyeon, Kovacs, Michael A, Shi, Jianxin, Xu, Mai, Goldstein, Alisa M, Trower, Adam J, Bishop, D Timothy, Iles, Mark M, Duffy, David L, MacGregor, Stuart, Amundadottir, Laufey T, Law, Matthew H, Loftus, Stacie K, Pavan, William J, Brown, Kevin M

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It's PRIMETIME. Postoperative Avoidance of Radiotherapy: Biomarker Selection of Women at Very Low Risk of Local Recurrence von Kirwan, C.C, Coles, C.E, Bliss, J

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Ethnicity and outcome of young breast cancer patients in the United Kingdom: the POSH study von Copson, E, Maishman, T, Gerty, S, Eccles, B, Stanton, L, Cutress, R I, Altman, D G, Durcan, L, Simmonds, P, Jones, L, Tapper, W, Eccles, Diana

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The PROFILE Feasibility Study: Targeted Screening of Men With a Family History of Prostate Cancer von Castro, Elena, Mikropoulos, Christos, Bancroft, Elizabeth K., Dadaev, Tokhir, Goh, Chee, Taylor, Natalie, Saunders, Edward, Borley, Nigel, Keating, Diana, Page, Elizabeth C., Saya, Sibel, Hazell, Stephen, Livni, Naomi, deSouza, Nandita, Neal, David, Hamdy, Freddie C., Kumar, Pardeep, Antoniou, Antonis C., Kote‐Jarai, Zsofia, Eeles, Rosalind A., Ardern‐Jones, A., Ardern‐Jones, P., As, N., Dearnaley, D., Foster, C., Khoo, V., Lewis, S., Lilja, H., Melia, J., Moynihan, C., Pharoah, P., Sohaib, A.

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Family history and outcome of young patients with breast cancer in the UK (POSH study) von Eccles, B. K., Copson, E. R., Cutress, R. I., Maishman, T., Altman, D. G., Simmonds, P., Gerty, S. M., Durcan, L., Stanton, L., Eccles, D. M.

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Overlapping genetic architecture between Parkinson disease and melanoma von Dube, Umber, Ibanez, Laura, Budde, John P., Benitez, Bruno A., Davis, Albert A., Harari, Oscar, Iles, Mark M., Law, Matthew H., Brown, Kevin M., Cruchaga, Carlos

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Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer von Zuber, Verena, Bettella, Francesco, Witoelar, Aree, Andreassen, Ole A, Mills, Ian G, Urbanucci, Alfonso

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A Genome-wide Pleiotropy Scan for Prostate Cancer Risk von Panagiotou, Orestis A, Travis, Ruth C, Campa, Daniele, Berndt, Sonja I, Lindstrom, Sara, Kraft, Peter, Schumacher, Fredrick R, Siddiq, Afshan, Papatheodorou, Stefania I, Stanford, Janet L, Albanes, Demetrius, Virtamo, Jarmo, Weinstein, Stephanie J, Diver, W. Ryan, Gapstur, Susan M, Stevens, Victoria L, Boeing, Heiner, Bueno-de-Mesquita, H. Bas, Barricarte Gurrea, Aurelio, Kaaks, Rudolf, Khaw, Kay-Tee, Krogh, Vittorio, Overvad, Kim, Riboli, Elio, Trichopoulos, Dimitrios, Giovannucci, Edward, Stampfer, Meir, Haiman, Christopher, Henderson, Brian, Le Marchand, Loic, Gaziano, J. Michael, Hunter, David J, Koutros, Stella, Yeager, Meredith, Hoover, Robert N, Chanock, Stephen J, Wacholder, Sholom, Key, Timothy J, Tsilidis, Konstantinos K

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Reducing the need to travel: A new planning objective in the UK? von Pharoah, Tim

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