Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Syntha... von Wagman, Allan S, Boyce, Rustum S, Brown, Sean P, Fang, Eric, Goff, Dane, Jansen, Johanna M, Le, Vincent P, Levine, Barry H, Ng, Simon C, Ni, Zhi-Jie, Nuss, John M, Pfister, Keith B, Ramurthy, Savithri, Renhowe, Paul A, Ring, David B, Shu, Wei, Subramanian, Sharadha, Zhou, Xiaohui A, Shafer, Cynthia M, Harrison, Stephen D, Johnson, Kirk W, Bussiere, Dirksen E

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Discovery and optimization of novel pyridines as highly potent and selective glycogen synthase kinase 3 inhibitors von Ramurthy, Savithri, Pfister, Keith B., Boyce, Rustum S., Brown, Sean P., Costales, Abran Q., Desai, Manoj C., Fang, Eric, Levine, Barry H., Ng, Simon C., Nuss, John M., Ring, David B., Shafer, Cynthia M., Shu, Wei, Subramanian, Sharadha, Wagman, Allan S., Wang, Haixia, Bussiere, Dirksen E.

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Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer von Burger, Matthew T, Pecchi, Sabina, Wagman, Allan, Ni, Zhi-Jie, Knapp, Mark, Hendrickson, Thomas, Atallah, Gordana, Pfister, Keith, Zhang, Yanchen, Bartulis, Sarah, Frazier, Kelly, Ng, Simon, Smith, Aaron, Verhagen, Joelle, Haznedar, Joshua, Huh, Kay, Iwanowicz, Ed, Xin, Xiaohua, Menezes, Daniel, Merritt, Hanne, Lee, Isabelle, Wiesmann, Marion, Kaufman, Susan, Crawford, Kenneth, Chin, Michael, Bussiere, Dirksen, Shoemaker, Kevin, Zaror, Isabel, Maira, Sauveur-Michel, Voliva, Charles F

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Inhibition of prenylated KRAS in a lipid environment von Jansen, Johanna M, Wartchow, Charles, Jahnke, Wolfgang, Fong, Susan, Tsang, Tiffany, Pfister, Keith, Zavorotinskaya, Tatiana, Bussiere, Dirksen, Cheng, Jan Marie, Crawford, Kenneth, Dai, Yumin, Dove, Jeffrey, Fang, Eric, Feng, Yun, Florent, Jean-Michel, Fuller, John, Gossert, Alvar D, Hekmat-Nejad, Mohammad, Henry, Chrystèle, Klopp, Julia, Lenahan, William P, Lingel, Andreas, Ma, Sylvia, Meyer, Arndt, Mishina, Yuji, Narberes, Jamie, Pardee, Gwynn, Ramurthy, Savithri, Rieffel, Sebastien, Stuart, Darrin, Subramanian, Sharadha, Tandeske, Laura, Widger, Stephania, Widmer, Armin, Winterhalter, Aurelie, Zaror, Isabel, Hardy, Stephen

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Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors von Burger, Matthew T, Knapp, Mark, Wagman, Allan, Ni, Zhi-Jie, Hendrickson, Thomas, Atallah, Gordana, Zhang, Yanchen, Frazier, Kelly, Verhagen, Joelle, Pfister, Keith, Ng, Simon, Smith, Aaron, Bartulis, Sarah, Merrit, Hanne, Weismann, Marion, Xin, Xiaohua, Haznedar, Joshua, Voliva, Charles F, Iwanowicz, Ed, Pecchi, Sabina

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Biased Complement Diversity Selection for Effective Exploration of Chemical Space in Hit-Finding Campaigns von Jansen, Johanna M, De Pascale, Gianfranco, Fong, Susan, Lindvall, Mika, Moser, Heinz E, Pfister, Keith, Warne, Bob, Wartchow, Charles

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Azaindoles as Zinc‐Binding Small‐Molecule Inhibitors of the JAMM Protease CSN5 von Altmann, Eva, Erbel, Paul, Renatus, Martin, Schaefer, Michael, Schlierf, Anita, Druet, Adelaide, Kieffer, Laurence, Sorge, Mickael, Pfister, Keith, Hassiepen, Ulrich, Jones, Matthew, Ruedisser, Simon, Ostermeier, Daniela, Martoglio, Bruno, Jefferson, Anne B., Quancard, Jean

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Discovery of a Selective and Potent Inhibitor of Mitogen-Activated Protein Kinase-Interacting Kinases 1 and 2 (MNK1/2) Utilizing Structure-Based Drug Design von Han, Wooseok, Ding, Yu, Xu, Yongjin, Pfister, Keith, Zhu, Shejin, Warne, Bob, Doyle, Mike, Aikawa, Mina, Amiri, Payman, Appleton, Brent, Stuart, Darrin D, Fanidi, Abdallah, Shafer, Cynthia M

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Synthesis of cyclic and acyclic enol ethers (vinyl ethers) von Gassman, Paul G, Burns, Stephen J, Pfister, Keith B

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4-(Aminoalkylamino)-3-benzimidazole-quinolinones as potent CHK-1 inhibitors von Ni, Zhi-Jie, Barsanti, Paul, Brammeier, Nathan, Diebes, Anthony, Poon, Daniel J., Ng, Simon, Pecchi, Sabina, Pfister, Keith, Renhowe, Paul A., Ramurthy, Savithri, Wagman, Allan S., Bussiere, Dirksen E., Le, Vincent, Zhou, Yasheen, Jansen, Johanna M., Ma, Sylvia, Gesner, Thomas G.

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Abstract B38: Inhibiting mutated KRAS, a broken switch of effector pathways von Jansen, Johanna, Jahnke, Wolfgang, Fong, Susan, Tandeske, Laura, Wartchow, Charles, Pfister, Keith, Zavorotinskaya, Tatiana, Blechschmidt, Anke, Bussiere, Dirksen, Dai, Yumin, Dove, Jeff, Fang, Eric, Farley, David, Florent, Jean-Michel, Fuller, John, Gokhin, Simona, Gossert, Alvar, Hekmat-Nejad, Mohammad, Henry, Chrystèle, Klopp, Julia, Lenahan, Bill, Lingel, Andreas, Meyer, Arndt, Narberes, Jamie, Pardee, Gwynn, Paris, C Gregory, Ramurthy, Savithri, Renhowe, Paul, Rieffel, Sebastien, Shoemaker, Kevin, Subramanian, Sharadha, Tsang, Tiffany, Widger, Stephania, Widmer, Armin, Zaror, Isabel, Hardy, Stephen

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Azaindoles as Zinc‐Binding Small‐Molecule Inhibitors of the JAMM Protease CSN5 von Altmann, Eva, Erbel, Paul, Renatus, Martin, Schaefer, Michael, Schlierf, Anita, Druet, Adelaide, Kieffer, Laurence, Sorge, Mickael, Pfister, Keith, Hassiepen, Ulrich, Jones, Matthew, Ruedisser, Simon, Ostermeier, Daniela, Martoglio, Bruno, Jefferson, Anne B., Quancard, Jean

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ANTIVIRAL 1,3-DI-OXO-INDENE COMPOUNDS von NEYTS, Johan, PFISTER, Keith Bruce, POON, Daniel

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ANTIVIRAL 1,3-DI-OXO-INDENE COMPOUNDS von NEYTS, Johan, PFISTER, Keith Bruce, POON, Daniel

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FUSED TRICYCLIC PYRAZOLO-DIHYDROPYRAZINYL-PYRIDONE COMPOUNDS AS ANTIVIRALS von Fu, Jiping, Jin, Xianming, Han, Wooseok, Young, Joseph Michael, Pfister, Keith Bruce

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Fused tricyclic pyrazolo-dihydropyrazinyl-pyridone compounds as antivirals von Fu, Jiping, Jin, Xianming, Han, Wooseok, Young, Joseph Michael, Pfister, Keith Bruce

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Antiviral 1,3-di-oxo-indene compounds von Lee, Sang-Ho, Lee, Chong-Kyo, Jung, Young-Sik, Chakrasali, Prashant, Shin, Jin Soo, Poon, Daniel, Malpani, Yashwardhan R, Kim, Chonsaeng, Han, Soo Bong, Kim, Hae Soo, Neyts, Johan, Pfister, Keith Bruce

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Antiviral 1,3-di-oxo-indene compounds von MALPANI, Yashwardhan R, KIM, Chonsaeng, NEYTS, Johan, PFISTER, Keith Bruce, POON, Daniel, LEE, Chong-Kyo, HAN, Soo Bong, SHIN, Jin Soo, KIM, Hae Soo, CHAKRASALI, Prashant, JUNG, Young-Sik, LEE, Sang-Ho

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Fused Tricyclic Pyrazolo-Dihydropyrazinyl-Pyridone Compounds as Antivirals von HAN, Wooseok, PFISTER, Keith Bruce, YOUNG, Joseph Michael, FU, Jiping, JIN, Xianming

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Antiviral 1,3-di-oxo-indene compounds von MALPANI, Yashwardhan R, BISWAS, Bishyajit Kumar, KIM, Chonsaeng, NEYTS, Johan, PFISTER, Keith Bruce, POON, Daniel, LEE, Chong-Kyo, HAN, Soo Bong, SHIN, Jin Soo, KIM, Hae Soo, CHAKRASALI, Prashant, JUNG, Young-Sik

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