Discovery of a Potent, Selective, and Orally Active Proteasome Inhibitor for the Treatment of Cancer von Dorsey, Bruce D, Iqbal, Mohamed, Chatterjee, Sankar, Menta, Ernesto, Bernardini, Raffaella, Bernareggi, Alberto, Cassarà, Paolo G, D’Arasmo, Germano, Ferretti, Edmondo, De Munari, Sergio, Oliva, Ambrogio, Pezzoni, Gabriella, Allievi, Cecilia, Strepponi, Ivan, Ruggeri, Bruce, Ator, Mark A, Williams, Michael, Mallamo, John P

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Formaldehyde-Activated Pixantrone Is a Monofunctional DNA Alkylator That Binds Selectively to CpG and CpA Doublets von Evison, Benny J, Chiu, Francis, Pezzoni, Gabriella, Phillips, Don R, Cutts, Suzanne M

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BBR 3464: A Novel Triplatinum Complex, Exhibiting a Preclinical Profile of Antitumor Efficacy Different from Cisplatin von MANZOTTI, C, PRATESI, G, PEZZONI, G, ZUNINO, F, MENTA, E, DI DOMENICO, R, CAVALLETTI, E, FIEBIG, H. H, KELLAND, L. R, FARRELL, N, POLIZZI, D, SUPINO, R

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A Novel Trinuclear Platinum Complex Overcomes Cisplatin Resistance in an Osteosarcoma Cell System von Perego, P, Caserini, C, Gatti, L, Carenini, N, Romanelli, S, Supino, R, Colangelo, D, Viano, I, Leone, R, Spinelli, S, Pezzoni, G, Manzotti, C, Farrell, N, Zunino, F

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CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib von Piva, Roberto, Ruggeri, Bruce, Williams, Michael, Costa, Giulia, Tamagno, Ilaria, Ferrero, Dario, Giai, Valentina, Coscia, Marta, Peola, Silvia, Massaia, Massimo, Pezzoni, Gabriella, Allievi, Cecilia, Pescalli, Nicoletta, Cassin, Mara, di Giovine, Stefano, Nicoli, Paola, de Feudis, Paola, Strepponi, Ivan, Roato, Ilaria, Ferracini, Riccardo, Bussolati, Benedetta, Camussi, Giovanni, Jones-Bolin, Susan, Hunter, Kathryn, Zhao, Hugh, Neri, Antonino, Palumbo, Antonio, Berkers, Celia, Ovaa, Huib, Bernareggi, Alberto, Inghirami, Giorgio

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Synthesis and Antitumor Evaluation of 2,5-Disubstituted- Indazolo[4,3-g h]isoquinolin-6(2H)-ones (9-Aza-anthrapyrazoles) von Krapcho, A. Paul, Menta, Ernesto, Oliva, Ambrogio, Di Domenico, Roberto, Fiocchi, Luigi, Maresch, Martin E, Gallagher, Cynthia E, Hacker, Miles P, Beggiolin, Gino, Giuliani, Fernando C, Pezzoni, Gabriella, Spinelli, Silvano

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Dual action of NAMI-A in inhibition of solid tumor metastasis: Selective targeting of metastatic cells and binding to collagen von SAVA, Gianni, ZORZET, Sonia, SARTOR, Luigi, GARBISA, Spiridione, TURRIN, Claudia, VITA, Francesca, SORANZO, Mariarosa, ZABUCCHI, Giuliano, COCCHIETTO, Moreno, BERGAMO, Alberta, DIGIOVINE, Stefano, PEZZONI, Gabriella

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Biological and clinical characterization of paclitaxel poliglumex (PPX, CT-2103), a macromolecular polymer-drug conjugate von Chipman, Stewart D, Oldham, Fred B, Pezzoni, Gabriella, Singer, Jack W

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Tri-, tetra- and heptacyclic perylene analogues as new potential antineoplastic agents based on DNA telomerase inhibition von Sissi, Claudia, Lucatello, Lorena, Paul Krapcho, A., Maloney, David J., Boxer, Matthew B., Camarasa, Maria V., Pezzoni, Gabriella, Menta, Ernesto, Palumbo, Manlio

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CpG methylation potentiates pixantrone and doxorubicin-induced DNA damage and is a marker of drug sensitivity von Evison, Benny J, Bilardi, Rebecca A, Chiu, Francis C.K, Pezzoni, Gabriella, Phillips, Don R, Cutts, Suzanne M

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A Novel 9-Aza-Anthrapyrazole Effective against Human Prostatic Carcinoma Xenografts von Supino, Rosanna, Polizzi, Donatella, Pavesi, Raffaella, Pratesi, Graziella, Guano, Fulvio, Capranico, Giovanni, Palumbo, Manlio, Sissi, Claudia, Richter, Silvia, Beggiolin, Gino, Menta, Ernesto, Pezzoni, Gabriella, Spinelli, Silvano, Torriani, Dante, Carenini, Nives, Dal Bo, Laura, Facchinetti, Federica, Tortoreto, Monica, Zunino, Franco

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Lysophosphatidic acid acyltransferase-β is a prognostic marker and therapeutic target in gynecologic malignancies von SPRINGETT, Gregory M, BONHAM, Lynn, SPRIGGS, David, SOSLOW, Robert, DUPONT, Jakob, HUMMER, Amanda, LINKOV, Irina, MISRA, Dipika, MA, Chia, PEZZONI, Gabriella, DI GIOVINE, Stefano, SINGER, Jack, KAWASAKI, Hiroaki

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Pixantrone (BBR2778) Reduces the Severity of Experimental Autoimmune Myasthenia Gravis in Lewis Rats von Ubiali, Federica, Nava, Sara, Nessi, Valeria, Longhi, Renato, Pezzoni, Gabriella, Capobianco, Raffaella, Mantegazza, Renato, Antozzi, Carlo, Baggi, Fulvio

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Novel Bis-platinum Complexes Endowed with an Improved Pharmacological Profile von Gatti, Laura, Perego, Paola, Leone, Roberto, Apostoli, Piero, Carenini, Nives, Corna, Elisabetta, Allievi, Cecilia, Bastrup, Ulla, De Munari, Sergio, Di Giovine, Stefano, Nicoli, Paola, Grugni, Mario, Natangelo, Marco, Pardi, Gianluca, Pezzoni, Gabriella, Singer, Jack W, Zunino, Franco

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Synthesis and antitumor evaluations of symmetrically and unsymmetrically substituted 1,4-bis[(aminoalkyl)amino]anthracene-9,10-diones and 1,4-bis[(aminoalkyl)amino]-5,8-dihydroxyan... von Krapcho, A. Paul, Getahun, Zelleka, Avery, Kenneth L, Vargas, Kevin J, Hacker, Miles P, Spinelli, Silvano, Pezzoni, Gabriella, Manzotti, Carla

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A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line von PEREGO, Paola, DE CESARE, Michelandrea, CARMINATI, Paolo, SCHEFFER, George L, ZUNINO, Franco, DE ISABELLA, Paola, CARENINI, Nives, BEGGIOLIN, Gino, PEZZONI, Gabriella, PALUMBO, Manlio, TARTAGLIA, Loris, PRATESI, Graziella, PISANO, Claudio

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Cytotoxicity evaluation of natural coptisine and synthesis of coptisine from berberine von Colombo, Maria Laura, Bugatti, Carlo, Mossa, Andrea, Pescalli, Nicoletta, Piazzoni, Laura, Pezzoni, Gabriella, Menta, Ernesto, Spinelli, Silvano, Johnson, Francis, Gupta, Ramesh C, Dasaradhi, Lakkaraju

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Biological and clinical characterization of paclitaxel poliglumex (PPX, CT-2103), a macromolecular polymeradrug conjugate von Chipman, Stewart D, Oldham, Fred B, Pezzoni, Gabriella, Singer, Jack W

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Bbr 2778, an aza-anthracenedione endowed with preclinical anticancer activity and lack of delayed cardiotoxicity von Beggiolin, G, Crippa, L, Menta, E, Manzotti, C, Cavalletti, E, Pezzoni, G, Torriani, D, Randisi, E, Cavagnoli, R, Sala, F, Giuliani, F C, Spinelli, S

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Reduced glutathione protects against cisplatin-induced neurotoxicity in rats von HAMERS, F. P. T, BRAKKEE, J. H, CAVALLETTI, E, TEDESCHI, M, MARMONTI, L, PEZZONI, G, NEIJT, J. P, GISPEN, W. H

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