Digital twin predicting diet response before and after long-term fasting von Silfvergren, Oscar, Simonsson, Christian, Ekstedt, Mattias, Lundberg, Peter, Gennemark, Peter, Cedersund, Gunnar

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Integrative model of the response of yeast to osmotic shock von Klipp, E, Nordlander, B, Kruger, R, Gennemark, P, Hohmann, S

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PPARγ and PPARα synergize to induce robust browning of white fat in vivo von Kroon, Tobias, Harms, Matthew, Maurer, Stefanie, Bonnet, Laurianne, Alexandersson, Ida, Lindblom, Anna, Ahnmark, Andrea, Nilsson, Daniel, Gennemark, Peter, O'Mahony, Gavin, Osinski, Victoria, McNamara, Coleen, Boucher, Jeremie

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Integrated experimental-computational analysis of a HepaRG liver-islet microphysiological system for human-centric diabetes research von Casas, Belén, Vilén, Liisa, Bauer, Sophie, Kanebratt, Kajsa P, Wennberg Huldt, Charlotte, Magnusson, Lisa, Marx, Uwe, Andersson, Tommy B, Gennemark, Peter, Cedersund, Gunnar

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A multi-scale digital twin for adiposity-driven insulin resistance in humans: diet and drug effects von Herrgårdh, Tilda, Simonsson, Christian, Ekstedt, Mattias, Lundberg, Peter, Stenkula, Karin G, Nyman, Elin, Gennemark, Peter, Cedersund, Gunnar

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Tissue pharmacokinetics of antisense oligonucleotides von Bäckström, Erica, Bonetti, Alessandro, Johnsson, Per, Öhlin, Stefan, Dahlén, Anders, Andersson, Patrik, Andersson, Shalini, Gennemark, Peter

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Unlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and Implications for Treatment of Diabetes and Obesity von Peng, Xiao-Rong, Gennemark, Peter, O'Mahony, Gavin, Bartesaghi, Stefano

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Abstract 13307: An Oral Antisense Oligonucleotide for PCSK9 Inhibition in Humans von Gennemark, Peter, Walter, Katrin, Clemmensen, Niclas, Rekic, Dinko, Nilsson, Catarina, Knoechel, Jane, Holtta, Mikko, Wang, Yanfeng, Yu, Rosie, riney, stanley, Monia, Brett P, Andersson, Ulf, Jansson-Lofmark, Rasmus, Rocha, Cristina S, Linden, Daniel, Ryden-Bergsten, Kristina, Hurt-Camejo, Eva, CROOKE, Rosanne M, Tillman, Lloyd, Carlsson, Bjorn, Elebring, Marie, Tivesten, Anna, Davies, Nigel

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Hybrid modelling for stroke care: Review and suggestions of new approaches for risk assessment and simulation of scenarios von Herrgårdh, Tilda, Madai, Vince I., Kelleher, John D., Magnusson, Rasmus, Gustafsson, Mika, Milani, Lili, Gennemark, Peter, Cedersund, Gunnar

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Effects of a novel potent melanin‐concentrating hormone receptor 1 antagonist, AZD1979, on body weight homeostasis in mice and dogs von Ploj, Karolina, Benthem, Lambertus, Kakol‐Palm, Dorota, Gennemark, Peter, Andersson, Liselotte, Bjursell, Mikael, Börjesson, Jenny, Kärrberg, Lillevi, Månsson, Marianne, Antonsson, Madeleine, Johansson, Anders, Iverson, Suzanne, Carlsson, Björn, Turnbull, Andrew, Lindén, Daniel

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A case‐study of model‐informed drug development of a novel PCSK9 anti sense oligonucleotide. Part 1: First time in man to phase II von Knöchel, Jane, Nilsson, Catarina, Carlsson, Björn, Wernevik, Linda, Hofherr, Alexis, Gennemark, Peter, Jansson‐Löfmark, Rasmus, Isaksson, Rikard, Rydén‐Bergsten, Tina, Hamrén, Bengt, Rekić, Dinko

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Network modeling of the transcriptional effects of copy number aberrations in glioblastoma von Jörnsten, Rebecka, Abenius, Tobias, Kling, Teresia, Schmidt, Linnéa, Johansson, Erik, Nordling, Torbjörn E M, Nordlander, Bodil, Sander, Chris, Gennemark, Peter, Funa, Keiko, Nilsson, Björn, Lindahl, Linda, Nelander, Sven

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Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system von Rigal, Sophie, Casas, Belén, Kanebratt, Kajsa P., Wennberg Huldt, Charlotte, Magnusson, Lisa U., Müllers, Erik, Karlsson, Fredrik, Clausen, Maryam, Hansson, Sara F., Leonard, Louise, Cairns, Jonathan, Jansson Löfmark, Rasmus, Ämmälä, Carina, Marx, Uwe, Gennemark, Peter, Cedersund, Gunnar, Andersson, Tommy B., Vilén, Liisa K.

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Inhibition of SGLT2 Preserves Function and Promotes Proliferation of Human Islets Cells In Vivo in Diabetic Mice von Karlsson, Daniel, Ahnmark, Andrea, Sabirsh, Alan, Andréasson, Anne-Christine, Gennemark, Peter, Sandinge, Ann-Sofie, Chen, Lihua, Tyrberg, Björn, Lindén, Daniel, Sörhede Winzell, Maria

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Model‐Based Analysis Reveals a Sustained and Dose‐Dependent Acceleration of Wound Healing by VEGF‐A mRNA (AZD8601) von Almquist, Joachim, Rikard, S. Michaela, Wågberg, Maria, Bruce, Anthony C., Gennemark, Peter, Fritsche‐Danielson, Regina, Chien, Kenneth R., Peirce, Shayn M., Hansson, Kenny, Lundahl, Anna

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Plasma Pharmacokinetics of N-Acetylgalactosamine-Conjugated Small-Interfering Ribonucleic Acids (GalNAc-Conjugated siRNAs) von Sten, Sebastian, Cardilin, Tim, Antonsson, Madeleine, Gennemark, Peter

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A unified framework for prediction of liver steatosis dynamics in response to different diet and drug interventions von Simonsson, Christian, Nyman, Elin, Gennemark, Peter, Gustafsson, Peter, Hotz, Ingrid, Ekstedt, Mattias, Lundberg, Peter, Cedersund, Gunnar

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3D cell aggregates amplify diffusion signals von Arjmandi, Hamidreza, Kanebratt, Kajsa P, Vilén, Liisa, Gennemark, Peter, Noel, Adam

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Benchmarks for identification of ordinary differential equations from time series data von Gennemark, Peter, Wedelin, Dag

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Cross-Species Translation of Biophase Half-Life and Potency of GalNAc-Conjugated siRNAs von Boianelli, Alessandro, Aoki, Yasunori, Ivanov, Maxim, Dahlén, Anders, Gennemark, Peter

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