Door, designed not to deviate significantly from imaginary line between lock bolts used to secure it in frame von JEROEN LUECKERS, PETER CHARLES MARIA SIMONS

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Door frame, has flexible part secured inside cavity in doorstep next to joint between doorstep and vertical frame member von JEROEN LUECKERS, PETER CHARLES MARIA SIMONS

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Glazing for door or window, has glass held in wooden frame by angled part with snap=fit fastener system von THEODORUS PETRUS MARTINUS MARIA ALKEMADE, ADRIANUS KOOIJMAN, JOHANNES PETRUS MARIA VAN WIJK, ELBERTUS JOSEPHUS GUSTAAF MARIA VAN LIESHOUT, ELCO RENE LOUWINGER, PETER CHARLES MARIA SIMONS

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Rucaparib or Physician’s Choice in Metastatic Prostate Cancer von Fizazi, Karim, Piulats, Josep M., Reaume, M. Neil, Ostler, Peter, McDermott, Ray, Gingerich, Joel R., Pintus, Elias, Sridhar, Srikala S., Bambury, Richard M., Emmenegger, Urban, Lindberg, Henriette, Morris, David, Nolè, Franco, Staffurth, John, Redfern, Charles, Sáez, María I., Abida, Wassim, Daugaard, Gedske, Heidenreich, Axel, Krieger, Laurence, Sautois, Brieuc, Loehr, Andrea, Despain, Darrin, Heyes, Catherine A., Watkins, Simon P., Chowdhury, Simon, Ryan, Charles J., Bryce, Alan H.

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Common polygenic variation enhances risk prediction for Alzheimer's disease von Escott-Price, Valentina, Sims, Rebecca, Bannister, Christian, Harold, Denise, Vronskaya, Maria, Majounie, Elisa, Badarinarayan, Nandini, Morgan, Kevin, Passmore, Peter, Holmes, Clive, Powell, John, Brayne, Carol, Gill, Michael, Mead, Simon, Goate, Alison, Cruchaga, Carlos, Lambert, Jean-Charles, van Duijn, Cornelia, Maier, Wolfgang, Ramirez, Alfredo, Holmans, Peter, Jones, Lesley, Hardy, John, Seshadri, Sudha, Schellenberg, Gerard D, Amouyel, Philippe, Williams, Julie

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Artificial intelligence-based pathology as a biomarker of sensitivity to atezolizumab–bevacizumab in patients with hepatocellular carcinoma: a multicentre retrospective study von Zeng, Qinghe, Klein, Christophe, Caruso, Stefano, Maille, Pascale, Allende, Daniela S, Mínguez, Beatriz, Ningarhari, Massih, Casadei-Gardini, Andrea, Rimini, Margherita, Perbellini, Riccardo, Boulagnon-Rombi, Camille, Rela, Mohamed, Vij, Mukul, Baulande, Sylvain, Lameiras, Sonia, Allende, Daniela S, Amaddeo, Giuliana, Argemi, Josepmaria, Beaufrère, Aurélie, Bermúdez-Ramos, María, Boulagnon-Rombi, Camille, Boursier, Jérôme, Calderaro, Julien, Campani, Claudia, Caruso, Stefano, Casadei-Gardini, Andrea, Castano Garcia, Andres, Chan, Stephen Lam, Di Tommaso, Luca, Digklia, Antonia, Garcia-Porrero, Guillermo, Ghaffari Laleh, Narmin, Gopal, Purva, Graham, Rondell P., Iavarone, Massimo, Iñarrairaegui, Mercedes, Kather, Jakob Nikolas, Klein, Christophe, Labgaa, Ismail, Lameiras, Sonia, Legoix, Patricia, Lequoy, Marie, Leung, Howard Ho-Wai, Loménie, Nicolas, Maggioni, Marco, Maille, Pascale, Marín-Zuluaga, Juan Ignacio, Mendoza-Pacas, Guillermo, Mínguez, Beatriz, El Nahhas, Omar S M, Nault, Jean-Charles, Ningarhari, Massih, Paradis, Valérie, Park, Young Nyun, Pawlotsky, Jean-Michel, Pedica, Federica, Perbellini, Riccardo, Pinato, David James, Pinter, Matthias, Radu, Pompilia, Regnault, Hélène, Reig, Maria, Rela, Mohamed, Rhee, Hyungjin, Rimassa, Lorenza, Sangro, Bruno, Scheiner, Bernhard, Sempoux, Christine, Su, Tung-Hung, Torres, Callie, Trépo, Eric, Varela, Maria, Verset, Gontran, Vij, Mukul, Vogel, Arndt, Zeng, Qinghe, Ziol, Marianne, Bruges, Léa, Gnemmi, Viviane, Nault, Jean-Charles, Campani, Claudia, Rhee, Hyungjin, Park, Young Nyun, Garcia-Porrero, Guillermo, Argemi, Josepmaria, Sangro, Bruno, D'Alessio, Antonio, Scheiner, Bernhard, Pinato, David James, Pinter, Matthias, Paradis, Valérie, Beaufrère, Aurélie, Peter, Simon, Rimassa, Lorenza, Di Tommaso, Luca, Vogel, Arndt, Michalak, Sophie, Boursier, Jérôme, Ziol, Marianne, Calderaro, Julien

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Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer von Tutt, Andrew N.J, Garber, Judy E, Kaufman, Bella, Viale, Giuseppe, Fumagalli, Debora, Rastogi, Priya, Gelber, Richard D, de Azambuja, Evandro, Fielding, Anitra, Balmaña, Judith, Domchek, Susan M, Gelmon, Karen A, Hollingsworth, Simon J, Korde, Larissa A, Linderholm, Barbro, Bandos, Hanna, Senkus, Elżbieta, Suga, Jennifer M, Shao, Zhimin, Pippas, Andrew W, Nowecki, Zbigniew, Huzarski, Tomasz, Ganz, Patricia A, Lucas, Peter C, Baker, Nigel, Loibl, Sibylle, McConnell, Robin, Piccart, Martine, Schmutzler, Rita, Steger, Guenther G, Costantino, Joseph P, Arahmani, Amal, Wolmark, Norman, McFadden, Eleanor, Karantza, Vassiliki, Lakhani, Sunil R, Yothers, Greg, Campbell, Christine, Geyer, Charles E

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Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis von Weaver, Jamie M J, Ross-Innes, Caryn S, Shannon, Nicholas, Lynch, Andy G, Forshew, Tim, Barbera, Mariagnese, Murtaza, Muhammed, Ong, Chin-Ann J, Lao-Sirieix, Pierre, Dunning, Mark J, Smith, Laura, Smith, Mike L, Anderson, Charlotte L, Carvalho, Benilton, O'Donovan, Maria, Underwood, Timothy J, May, Andrew P, Grehan, Nicola, Hardwick, Richard, Davies, Jim, Oloumi, Arusha, Aparicio, Sam, Caldas, Carlos, Eldridge, Matthew D, Edwards, Paul A W, Rosenfeld, Nitzan, Tavaré, Simon, Fitzgerald, Rebecca C

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TREM2 Variants in Alzheimer's Disease von Guerreiro, Rita, Wojtas, Aleksandra, Bras, Jose, Carrasquillo, Minerva, Rogaeva, Ekaterina, Majounie, Elisa, Cruchaga, Carlos, Sassi, Celeste, Kauwe, John S.K, Younkin, Steven, Hazrati, Lilinaz, Collinge, John, Pocock, Jennifer, Lashley, Tammaryn, Williams, Julie, Lambert, Jean-Charles, Amouyel, Philippe, Goate, Alison, Rademakers, Rosa, Morgan, Kevin, Powell, John, St. George-Hyslop, Peter, Singleton, Andrew, Hardy, John

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Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial von Iwata, Hiroji, Chia, Stephen K L, Bashford, Anna, Inoue, Kenichi, Armstrong, Anne C, Wong, Alvin, Buyse, Marc, Harvey, Vernon, Smith, John W., Konstantinovic, Zora Neskovic, Rodriguez, Gladys I., Jáñez Martinez, Noelia, Knoop, Ann Soegaard, De Boer, Richard Hendry, Rai, Yoshiaki, Yamamoto, Naohito, Brincat, Stephen, Papish, Steven William, Manalo, Yvonne, Sorensen, Peter Grundtvig, Aogi, Kenjiro, Shimizu, Satoru, Mainwaring, Paul, Chang, Jose, del Barco Berron, Sonia, Dickerson, Laura C., Klein, Leonard M., Ruxer, Robert, Veyret, Corinne, Wagnerova, Maria, Richards, Donald A., Vasileios, Asskikis, Dourthe, Louis Marie, Lu, Yen-Shen, Greenspan, Andrew R., Gonzalez Santiago, Santiago, Perren, Timothy John, Yau, Chung Cheung Thomas, Pikó, Béla, Sato, Nobuaki, Askoy, Sercan, Altundag, Mustafa Kadri, Saip, Pinar, Bajaj, Rajesh, Vestlev, Peter Michael, Dank, Magdolna, Cinieri, Saverio, Suszko-Kazarnowicz, Malgorzata, Yap, Yoon Sim, Chen, Shin-Cheh, Haley, Barbara Bacsik, Inhorn, Roger C., Koynova, Tatyana, Schneeweiss, Andreas, Cubedo Cervera, Ricardo, Urruticoechea Ribate, Ander, Schwartz, Garry H., Mocharnuk, Robert Scott, Alkhouri, Nabiel, Erickson, Nicholette, Traynor, Ann, Volterra, Fabio, Capo, Gerardo, Flaherty, Lawrence E., Baidas, Said, Lybaert, Willem, Holland, David R., Gonzalez Jimenez, Sonia, Vanlemmens, Laurence, Ruggeri, Enzo Maria, Desai, Ajit, Nixon, David Allen, O'Brien, Edward, Lanier, Keith S., Brescia, Frankie Ann, Richard, Vincent, Geldhof, Kurt, Bednarik, Otakar, Schwedler, Kathrin, Fries, Stefan, Klare, Peter, Griesinger, Frank, Trufflandier, Nathalie, Chetiyawardana, Anula D., Papandreou, Christos, Hornyak, Lajos, Simo, Erzsebet, Im, Seock-Ah, Ruit, Jan B., Ciltas, Aydin, Benekli, Mustafa, Conkright, William A., Ottaviano, Yvonne, Delmas, Andrew, Steele, Heather A., Bova, Abby R., Shirinian, Mihran, O'Rourke, Timothy J., Francisco, Michael, Carrillo Flores, Maria Regina

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Antibacterial Envelope to Prevent Cardiac Implantable Device Infection von Tarakji, Khaldoun G, Mittal, Suneet, Kennergren, Charles, Corey, Ralph, Poole, Jeanne E, Schloss, Edward, Gallastegui, Jose, Pickett, Robert A, Evonich, Rudolph, Philippon, François, McComb, Janet M, Roark, Steven F, Sorrentino, Denise, Sholevar, Darius, Cronin, Edmond, Berman, Brett, Riggio, David, Biffi, Mauro, Khan, Hafiza, Silver, Marc T, Collier, Jack, Eldadah, Zayd, Wright, David J, Lande, Jeff D, Lexcen, Daniel R, Cheng, Alan, Wilkoff, Bruce L

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Intramyocardial, Autologous CD34+ Cell Therapy for Refractory Angina von Losordo, Douglas W, Henry, Timothy D, Davidson, Charles, Sup Lee, Joon, Costa, Marco A, Bass, Theodore, Mendelsohn, Farrell, Fortuin, F David, Pepine, Carl J, Traverse, Jay H, Amrani, David, Ewenstein, Bruce M, Riedel, Norbert, Story, Kenneth, Barker, Kerry, Povsic, Thomas J, Harrington, Robert A, Schatz, Richard A

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The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic von Frankell, Alexander M., Jammula, SriGanesh, Li, Xiaodun, Contino, Gianmarco, Killcoyne, Sarah, Abbas, Sujath, Perner, Juliane, Bower, Lawrence, Devonshire, Ginny, Ococks, Emma, Grehan, Nicola, Mok, James, O’Donovan, Maria, MacRae, Shona, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C.

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Whole-genome sequencing provides new insights into the clonal architecture of Barrett's esophagus and esophageal adenocarcinoma von Ross-Innes, Caryn S, Becq, Jennifer, Warren, Andrew, Cheetham, R Keira, Northen, Helen, O'Donovan, Maria, Malhotra, Shalini, di Pietro, Massimiliano, Ivakhno, Sergii, He, Miao, Weaver, Jamie M J, Lynch, Andy G, Kingsbury, Zoya, Ross, Mark, Humphray, Sean, Bentley, David, Fitzgerald, Rebecca C

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Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease St... von 2013 Mortality And Causes of Death Collaborators, Gbd, Aboyans, Victor

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Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial von Johnstone, Jennie, Meade, Maureen, Lauzier, François, Marshall, John, Duan, Erick, Dionne, Joanna, Arabi, Yaseen M, Heels-Ansdell, Diane, Thabane, Lehana, Lamarche, Daphnee, Surette, Michael, Zytaruk, Nicole, Mehta, Sangeeta, Dodek, Peter, McIntyre, Lauralyn, English, Shane, Rochwerg, Bram, Karachi, Tim, Henderson, William, Wood, Gordon, Ovakim, Daniel, Herridge, Margaret, Granton, John, Wilcox, M. Elizabeth, Goffi, Alberto, Stelfox, Henry T, Niven, Daniel, Muscedere, John, Lamontagne, François, D’Aragon, Frédérick, St.-Arnaud, Charles, Ball, Ian, Nagpal, Dave, Girard, Martin, Aslanian, Pierre, Charbonney, Emmanuel, Williamson, David, Sligl, Wendy, Friedrich, Jan, Adhikari, Neill K, Marquis, François, Archambault, Patrick, Khwaja, Kosar, Kristof, Arnold, Kutsogiannis, James, Zarychanski, Ryan, Paunovic, Bojan, Reeve, Brenda, Lellouche, François, Hosek, Paul, Tsang, Jennifer, Binnie, Alexandra, Trop, Sébastien, Loubani, Osama, Hall, Richard, Cirone, Robert, Reynolds, Steve, Lysecki, Paul, Golan, Eyal, Cartin-Ceba, Rodrigo, Taylor, Robert, Cook, Deborah

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Neoadjuvant chemotherapy versus debulking surgery in advanced tubo-ovarian cancers: pooled analysis of individual patient data from the EORTC 55971 and CHORUS trials von Vergote, Ignace, Coens, Corneel, Nankivell, Matthew, Kristensen, Gunnar B, Parmar, Mahesh K B, Jayson, Gordon C, Swart, Ann Marie, Verheijen, René, McCluggage, W Glenn, Perren, Tim, Panici, Pierluigi Benedetti, Kenter, Gemma, Casado, Antonio, Mendiola, Cesar, Stuart, Gavin, Reed, Nick S, Kehoe, Sean, Tropé G., Claes, Dobbs, Stephen, Essapen, Sharadah, Hoskins, P., Van Baal, M., Twigg, Jeremy, Van Der Burg, Maria E.L., Godfrey, Keith, Lacave, Angel J., Redman, Charles, Lotocki, R., Olaitan, Adeola, Mosgaard, B., Rustin, G., Persic, Mojca, Hogg, Martin, Van Der Velden, J., Ledermann, J., Peter Sykes, Peter Sykes, Hird, Vicky, Sandvei R., R., Cruickshank, D.J., Ottevanger, P.B., Pearson, Sheila, Hall, Marcia, Bessette, P., Gerdin, E., Lopes, Tito, Fish, Andrew, Van Eygen, K., Floquet, A., Tholander, B., Gul, N., Gornall, Robert, Luesley, David, Symonds, Paul, Poole, David, McNeish, Ian, Hocking, Mark, Sammaraie, Al, Speiser, P., Leblanc, E., De Oliveira, C.F., Grimshaw, R., Zola, P., Parkin, David, Lamb, Martin, Gillespie, Alan, Hamid, Abdel, Ahmed, Ahmed, Perez, David, Skailes, Geraldine, Jones, Rachel, Leeson, Simon, Elit, L., Gotlieb, W., Crosse, Barbara, Ridley, Paul, Head, Anthony, Nieto, Joaquin, Awwad, Saif, Brinkmann, Dirk, Eustace, Damian, Katsaros, D., Popadiuk, C., Redman, C., Chan, S., Marth, C., Lankaster, Kate, Indrajit, Fernando, Quigley, Mary, Adeyemi, Olu, McNally, Orla, Tristam, Amanda, Lee, Martin, Counsell, R., Gleeson, N., Papadopoulos, A., Maggino, T., Ghatage, P., Vermorken, J.B., Petru, E, Amant, F.

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Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease von Nalls, Mike A, Pankratz, Nathan, Lill, Christina M, Do, Chuong B, Hernandez, Dena G, Saad, Mohamad, DeStefano, Anita L, Kara, Eleanna, Bras, Jose, Sharma, Manu, Schulte, Claudia, Keller, Margaux F, Arepalli, Sampath, Letson, Christopher, Edsall, Connor, Stefansson, Hreinn, Liu, Xinmin, Pliner, Hannah, Lee, Joseph H, Cheng, Rong, Ikram, M Arfan, Ioannidis, John P A, Hadjigeorgiou, Georgios M, Bis, Joshua C, Martinez, Maria, Perlmutter, Joel S, Goate, Alison, Marder, Karen, Fiske, Brian, Sutherland, Margaret, Xiromerisiou, Georgia, Myers, Richard H, Clark, Lorraine N, Stefansson, Kari, Hardy, John A, Heutink, Peter, Chen, Honglei, Wood, Nicholas W, Houlden, Henry, Payami, Haydeh, Brice, Alexis, Scott, William K, Gasser, Thomas, Bertram, Lars, Eriksson, Nicholas, Foroud, Tatiana, Singleton, Andrew B

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Identification of Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data von Jammula, SriGanesh, Katz-Summercorn, Annalise C., Li, Xiaodun, Linossi, Constanza, Smyth, Elizabeth, Killcoyne, Sarah, Biasci, Daniele, Subash, Vinod V., Abbas, Sujath, Blasko, Adrienn, Devonshire, Ginny, Grantham, Amber, Wronowski, Filip, O’Donovan, Maria, Grehan, Nicola, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C., Noorani, Ayesha, Edwards, Paul A.W., Grehan, Nicola, Nutzinger, Barbara, Hughes, Caitriona, Fidziukiewicz, Elwira, Bornschein, Jan, MacRae, Shona, Crawte, Jason, Northrop, Alex, Contino, Gianmarco, Li, Xiaodun, de la Rue, Rachel, O’Donovan, Maria, Miremadi, Ahmad, Malhotra, Shalini, Tripathi, Monika, Tavaré, Simon, Lynch, Andy G., Eldridge, Matthew, Secrier, Maria, Bower, Lawrence, Devonshire, Ginny, Perner, Juliane, Jammula, Sriganesh, Davies, Jim, Crichton, Charles, Carroll, Nick, Safranek, Peter, Hindmarsh, Andrew, Sujendran, Vijayendran, Hayes, Stephen J., Ang, Yeng, Preston, Shaun R., Oakes, Sarah, Bagwan, Izhar, Save, Vicki, Skipworth, Richard J.E., Hupp, Ted R., O’Neill, J. Robert, Tucker, Olga, Beggs, Andrew, Taniere, Philippe, Puig, Sonia, Underwood, Timothy J., Noble, Fergus, Owsley, Jack, Barr, Hugh, Shepherd, Neil, Old, Oliver, Lagergren, Jesper, Gossage, James, Davies, Andrew, Chang, Fuju, Zylstra, Janine, Mahadeva, Ula, Goh, Vicky, Ciccarelli, Francesca D., Sanders, Grant, Berrisford, Richard, Harden, Catherine, Lewis, Mike, Cheong, Ed, Kumar, Bhaskar, Parsons, Simon L., Soomro, Irshad, Kaye, Philip, Saunders, John, Lovat, Laurence, Haidry, Rehan, Igali, Laszlo, Scott, Michael, Sothi, Sharmila, Suortamo, Sari, Lishman, Suzy, Hanna, George B., Moorthy, Krishna, Peters, Christopher J., Grabowska, Anna, Turkington, Richard, Fitzgerald, Rebecca C.

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Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients von Carr, Edward J, Wu, Mary, Harvey, Ruth, Wall, Emma C, Kelly, Gavin, Hussain, Saira, Howell, Michael, Kassiotis, George, Swanton, Charles, Gandhi, Sonia, Bauer, David LV, Adenwalla, Sherna F, Bird, Paul, Holmes, Christopher, Hull, Katherine L, March, Daniel S, Selvaskandan, Haresh, Silva, Jorge J, Tang, Julian W, Hester, Joanna, Issa, Fadi, Barnardo, Martin, Friend, Peter J, Davenport, Andrew, Goodlad, Catriona, Gopalan, Vignesh, Tangwonglert, Theerasak, Stauss, Hans J, Richter, Alex G, Cunningham, Adam F, Perez-Toledo, Marisol, Banham, Gemma D, Wall, Nadya, Clarke, Candice L, Prendecki, Maria, Clayton, Bobbi, Namjou, Sina, Silva, Vanessa, Poulten, Meghan, Bawumia, Philip, Miah, Murad, Sade, Samuel, Miranda, Mauro, Taylor, Tom, D'Angelo, Ilenia, Cabrera Jarana, Mercedes, Rahman, Mahbubur, Abreu, Janet, Sandhar, Sandeep, Bailey, Neil, Caidan, Simon, Caulfield, Marie, Wu, Mary, Harvey, Ruth, Adams, Lorin, Kavanagh, Caitlin, Warchal, Scott, Sawyer, Chelsea, Gavrielides, Mike, Kandasamy, Jag, Ambrose, Karen, Strange, Amy, Abiola, Titilayo, O'Reilly, Nicola, Hobson, Philip, Agau-Doce, Ana, Russell, Emma, Riddell, Andrew, Kjaer, Svend, Borg, Annabel, Roustan, Chloë, Billany, Roseanne E, Graham-Brown, Matthew PM, Beckett, Joseph, Bull, Katherine, Shankar, Sushma, Henderson, Scott, Motallebzadeh, Reza, Salama, Alan D, Harper, Lorraine, Mark, Patrick B, McAdoo, Stephen, Willicombe, Michelle, Beale, Rupert

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