Human Endogenous Retrovirus W in brain lesions: rationale for targeted therapy in Multiple Sclerosis von van Horssen, Jack, van der Pol, Susanne, Nijland, Philip, Amor, Sandra, Perron, Hervé

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The Human Endogenous Retrovirus Link between Genes and Environment in Multiple Sclerosis and in Multifactorial Diseases Associating Neuroinflammation von Perron, Hervé, Lang, Alois

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DNA sequences from mobile genetic elements, a hidden half of the human genome von Medina, Julie, Perron, Hervé

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Identification of inflammatory subgroups of schizophrenia and bipolar disorder patients with HERV-W ENV antigenemia by unsupervised cluster analysis von Tamouza, Ryad, Meyer, Urs, Foiselle, Marianne, Richard, Jean-Romain, Wu, Ching-Lien, Boukouaci, Wahid, Le Corvoisier, Philippe, Barrau, Caroline, Lucas, Alexandre, Perron, Hervé, Leboyer, Marion

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Variation in proviral content among human genomes mediated by LTR recombination von Thomas, Jainy, Perron, Hervé, Feschotte, Cédric

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Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation von Kremer, David, Schichel, Tanja, Förster, Moritz, Tzekova, Nevena, Bernard, Corinne, van der Valk, Paul, van Horssen, Jack, Hartung, Hans-Peter, Perron, Hervé, Küry, Patrick

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MSRV envelope protein is a potent, endogenous and pathogenic agonist of human toll-like receptor 4: Relevance of GNbAC1 in multiple sclerosis treatment von Madeira, Alexandra, Burgelin, Ingrid, Perron, Hervé, Curtin, Francois, Lang, Alois B, Faucard, Raphael

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Rescuing the negative impact of human endogenous retrovirus envelope protein on oligodendroglial differentiation and myelination von Göttle, Peter, Förster, Moritz, Gruchot, Joel, Kremer, David, Hartung, Hans Peter, Perron, Hervé, Küry, Patrick

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Human Endogenous Retrovirus Type W Envelope from Multiple Sclerosis Demyelinating Lesions Shows Unique Solubility and Antigenic Characteristics von Charvet, Benjamin, Pierquin, Justine, Brunel, Joanna, Gorter, Rianne, Quétard, Christophe, Horvat, Branka, Amor, Sandra, Portoukalian, Jacques, Perron, Hervé

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Evidence of the pathogenic HERV-W envelope expression in T lymphocytes in association with the respiratory outcome of COVID-19 patients von Balestrieri, Emanuela, Minutolo, Antonella, Petrone, Vita, Fanelli, Marialaura, Iannetta, Marco, Malagnino, Vincenzo, Zordan, Marta, Vitale, Pietro, Charvet, Benjamin, Horvat, Branka, Bernardini, Sergio, Garaci, Enrico, di Francesco, Paolo, Sinibaldi Vallebona, Paola, Sarmati, Loredana, Grelli, Sandro, Andreoni, Massimo, Perron, Hervé, Matteucci, Claudia

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Human endogenous retrovirus protein activates innate immunity and promotes experimental allergic encephalomyelitis in mice von Perron, Hervé, Dougier-Reynaud, Hei-Lanne, Lomparski, Christina, Popa, Iuliana, Firouzi, Reza, Bertrand, Jean-Baptiste, Marusic, Suzana, Portoukalian, Jacques, Jouvin-Marche, Evelyne, Villiers, Christian L, Touraine, Jean-Louis, Marche, Patrice N

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A new therapeutic approach for type 1 diabetes: Rationale for GNbAC1, an anti‐HERV‐W‐Env monoclonal antibody von Curtin, Francois, Bernard, Corinne, Levet, Sandrine, Perron, Hervé, Porchet, Hervé, Médina, Julie, Malpass, Sam, Lloyd, David, Simpson, Richard

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A tale of a hidden family of genetic immigrants von Perron, Hervé

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GNbAC1, a Humanized Monoclonal Antibody Against the Envelope Protein of Multiple Sclerosis—Associated Endogenous Retrovirus: A First-in-Humans Randomized Clinical Study von Curtin, François, MD, Lang, Alois B., PhD, Perron, Hervé, PhD, Laumonier, Marion, MSc, Vidal, Virginie, MSc, Porchet, Hervé C., MD, Hartung, Hans-Peter, MD

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Human Endogenous Retrovirus K Envelope in Spinal Fluid of Amyotrophic Lateral Sclerosis Is Toxic von Steiner, Joseph P., Bachani, Muzna, Malik, Nasir, DeMarino, Catherine, Li, Wenxue, Sampson, Kevon, Lee, Myoung‐Hwa, Kowalak, Jeffery, Bhaskar, Manju, Doucet‐O'Hare, Tara, Garcia‐Montojo, Marta, Cowen, Maria, Smith, Bryan, Reoma, Lauren Bowen, Medina, Julie, Brunel, Joanna, Pierquin, Justine, Charvet, Benjamin, Perron, Hervé, Nath, Avindra

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A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multipl... von Derfuss, Tobias, Curtin, François, Guebelin, Claudia, Bridel, Claire, Rasenack, Maria, Matthey, Alain, Du Pasquier, Renaud, Schluep, Myriam, Desmeules, Jules, Lang, Alois B, Perron, Hervé, Faucard, Raphael, Porchet, Hervé, Hartung, Hans-Peter, Kappos, Ludwig, Lalive, Patrice H

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The DNA copy number of human endogenous retrovirus-W (MSRV-type) is increased in multiple sclerosis patients and is influenced by gender and disease severity von Garcia-Montojo, Marta, Dominguez-Mozo, María, Arias-Leal, Ana, Garcia-Martinez, Ángel, De las Heras, Virginia, Casanova, Ignacio, Faucard, Raphaël, Gehin, Nadège, Madeira, Alexandra, Arroyo, Rafael, Curtin, François, Alvarez-Lafuente, Roberto, Perron, Hervé

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Preclinical and early clinical development of GNbAC1, a humanized IgG4 monoclonal antibody targeting endogenous retroviral MSRV-Env protein von Curtin, François, Perron, Hervé, Kromminga, Arno, Porchet, Hervé, Lang, Alois B

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Patients with psychosis spectrum disorders hospitalized during the COVID-19 pandemic unravel overlooked SARS-CoV-2 past infection clustering with HERV-W ENV expression and chronic... von Tamouza, Ryad, Meyer, Urs, Lucas, Alexandre, Richard, Jean Romain, Nkam, Irène, Pinot, Armand, Djonouma, Ndilyam, Boukouaci, Wahid, Charvet, Benjamin, Pierquin, Justine, Brunel, Joanna, Fourati, Slim, Rodriguez, Christophe, Barau, Caroline, Le Corvoisier, Philippe, El Abdellati, Kawtar, De Picker, Livia, Perron, Hervé, Leboyer, Marion

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The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease von Dolei, Antonina, Perron, Hervé

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