Multimodal techniques for diagnosis and prognosis of Alzheimer's disease von Holtzman, David M, Perrin, Richard J, Fagan, Anne M

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Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders von Yang, Chengran, Farias, Fabiana H. G., Ibanez, Laura, Suhy, Adam, Sadler, Brooke, Fernandez, Maria Victoria, Wang, Fengxian, Bradley, Joseph L., Eiffert, Brett, Bahena, Jorge A., Budde, John P., Li, Zeran, Dube, Umber, Sung, Yun Ju, Mihindukulasuriya, Kathie A., Morris, John C., Fagan, Anne M., Perrin, Richard J., Benitez, Bruno A., Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos

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Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy von Da Mesquita, Sandro, Papadopoulos, Zachary, Dykstra, Taitea, Brase, Logan, Farias, Fabiana Geraldo, Wall, Morgan, Jiang, Hong, Kodira, Chinnappa Dilip, de Lima, Kalil Alves, Herz, Jasmin, Louveau, Antoine, Goldman, Dylan H., Salvador, Andrea Francesca, Onengut-Gumuscu, Suna, Farber, Emily, Dabhi, Nisha, Kennedy, Tatiana, Milam, Mary Grace, Baker, Wendy, Smirnov, Igor, Rich, Stephen S., Benitez, Bruno A., Karch, Celeste M., Perrin, Richard J., Farlow, Martin, Chhatwal, Jasmeer P., Holtzman, David M., Cruchaga, Carlos, Harari, Oscar, Kipnis, Jonathan

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Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis von Craig-Schapiro, Rebecca, Kuhn, Max, Xiong, Chengjie, Pickering, Eve H, Liu, Jingxia, Misko, Thomas P, Perrin, Richard J, Bales, Kelly R, Soares, Holly, Fagan, Anne M, Holtzman, David M

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The timing of surgical intervention in the treatment of spinal cord injury: a systematic review of recent clinical evidence von Fehlings, Michael G, Perrin, Richard G

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A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain von Del-Aguila, Jorge L, Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A, Budde, John P, Fernandez, Maria Victoria, Ibanez, Laura, Bradley, Joseph, Wang, Fengxian, Bergmann, Kristy, Davenport, Richard, Morris, John C, Holtzman, David M, Perrin, Richard J, Benitez, Bruno A, Dougherty, Joseph, Cruchaga, Carlos, Harari, Oscar

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Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease von Eteleeb, Abdallah M, Novotny, Brenna C, Tarraga, Carolina Soriano, Sohn, Christopher, Dhungel, Eliza, Brase, Logan, Nallapu, Aasritha, Buss, Jared, Farias, Fabiana, Bergmann, Kristy, Bradley, Joseph, Norton, Joanne, Gentsch, Jen, Wang, Fengxian, Davis, Albert A, Morris, John C, Karch, Celeste M, Perrin, Richard J, Benitez, Bruno A, Harari, Oscar

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Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits von Wang, Ciyang, Yang, Chengran, Western, Daniel, Ali, Muhammad, Wang, Yueyao, Phuah, Chia-Ling, Budde, John, Wang, Lihua, Gorijala, Priyanka, Timsina, Jigyasha, Ruiz, Agustin, Pastor, Pau, Fernandez, Maria Victoria, Perrin, Richard, Panyard, Daniel J., Engelman, Corinne D., Deming, Yuetiva, Boada, Merce, Cano, Amanda, Garcia-Gonzalez, Pablo, Graff-Radford, Neill R., Mori, Hiroshi, Lee, Jae-Hong, Perrin, Richard J., Ibanez, Laura, Sung, Yun Ju, Cruchaga, Carlos

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Longitudinal Relationships of White Matter Hyperintensities and Alzheimer Disease Biomarkers Across the Adult Life Span von Luo, Jingqin, Ma, Yinjiao, Agboola, Folasade Jane, Grant, Elizabeth, Morris, John C, McDade, Eric, Fagan, Anne M, Benzinger, Tammie L S, Hassenstab, Jason, Bateman, Randall J, Perrin, Richard J, Gordon, Brian A, Goyal, Manu, Strain, Jeremy F, Yakushev, Igor, Day, Gregory S, Xiong, Chengjie

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Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community‐engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4 von Weiner, Michael W., Veitch, Dallas P., Miller, Melanie J., Aisen, Paul S., Albala, Bruce, Beckett, Laurel A., Green, Robert C., Harvey, Danielle, Jack, Clifford R., Jagust, William, Landau, Susan M., Morris, John C., Nosheny, Rachel, Okonkwo, Ozioma C., Perrin, Richard J., Petersen, Ronald C., Rivera‐Mindt, Monica, Saykin, Andrew J., Shaw, Leslie M, Toga, Arthur W., Tosun, Duygu, Trojanowski, John Q.

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Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes von Yang, Chengran, Fagan, Anne M, Perrin, Richard J, Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos

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Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers von Brase, Logan, You, Shih-Feng, D’Oliveira Albanus, Ricardo, Del-Aguila, Jorge L., Dai, Yaoyi, Novotny, Brenna C., Soriano-Tarraga, Carolina, Dykstra, Taitea, Fernandez, Maria Victoria, Budde, John P., Bergmann, Kristy, Morris, John C., Bateman, Randall J., Perrin, Richard J., McDade, Eric, Xiong, Chengjie, Goate, Alison M., Farlow, Martin, Sutherland, Greg T., Kipnis, Jonathan, Karch, Celeste M., Benitez, Bruno A., Harari, Oscar

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Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan von Luo, Jingqin, Agboola, Folasade, Grant, Elizabeth, Morris, John C, Masters, Colin L, Albert, Marilyn S, Johnson, Sterling C, McDade, Eric M, Fagan, Anne M, Benzinger, Tammie L S, Hassenstab, Jason, Bateman, Randall J, Perrin, Richard J, Wang, Guoqiao, Li, Yan, Gordon, Brian, Cruchaga, Carlos, Day, Gregory S, Levin, Johannes, Vöglein, Jonathan, Ikeuchi, Takeshi, Suzuki, Kazushi, Allegri, Ricardo F, Xiong, Chengjie

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Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue von Dhavale, Dhruva D., Barclay, Alexander M., Borcik, Collin G., Basore, Katherine, Berthold, Deborah A., Gordon, Isabelle R., Liu, Jialu, Milchberg, Moses H., O’Shea, Jennifer Y., Rau, Michael J., Smith, Zachary, Sen, Soumyo, Summers, Brock, Smith, John, Warmuth, Owen A., Perrin, Richard J., Perlmutter, Joel S., Chen, Qian, Fitzpatrick, James A. J., Schwieters, Charles D., Tajkhorshid, Emad, Rienstra, Chad M., Kotzbauer, Paul T.

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Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease von Perrin, Richard J, Craig-Schapiro, Rebecca, Malone, James P, Shah, Aarti R, Gilmore, Petra, Davis, Alan E, Roe, Catherine M, Peskind, Elaine R, Li, Ge, Galasko, Douglas R, Clark, Christopher M, Quinn, Joseph F, Kaye, Jeffrey A, Morris, John C, Holtzman, David M, Townsend, R Reid, Fagan, Anne M

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CSF tau microtubule-binding region identifies pathological changes in primary tauopathies von Horie, Kanta, Barthélemy, Nicolas R., Spina, Salvatore, VandeVrede, Lawren, He, Yingxin, Paterson, Ross W., Wright, Brenton A., Day, Gregory S., Davis, Albert A., Karch, Celeste M., Seeley, William W., Perrin, Richard J., Koppisetti, Rama K., Shaikh, Faris, Lago, Argentina Lario, Heuer, Hilary W., Ghoshal, Nupur, Gabelle, Audrey, Miller, Bruce L., Boxer, Adam L., Bateman, Randall J., Sato, Chihiro

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Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease von Veitch, Dallas P., Weiner, Michael W., Aisen, Paul S., Beckett, Laurel A., DeCarli, Charles, Green, Robert C., Harvey, Danielle, Jack, Clifford R., Jagust, William, Landau, Susan M., Morris, John C., Okonkwo, Ozioma, Perrin, Richard J., Petersen, Ronald C., Rivera‐Mindt, Monica, Saykin, Andrew J., Shaw, Leslie M., Toga, Arthur W., Tosun, Duygu, Trojanowski, John Q.

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A Half-Century of Yield Growth along the Forty-First Parallel of the Great Plains von Trindade, Federico J, Fulginiti, Lilyan E, Perrin, Richard K

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TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers von Del-Aguila, Jorge L, Benitez, Bruno A, Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A, Budde, John P, Farias, Fabiana H G, Fernández, Maria Victoria, Ibanez, Laura, Jiang, Shan, Perrin, Richard J, Cairns, Nigel J, Morris, John C, Harari, Oscar, Cruchaga, Carlos

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Preclinical Alzheimer's disease biomarkers accurately predict cognitive and neuropathological outcomes von Long, Justin M, Coble, Dean W, Xiong, Chengjie, Schindler, Suzanne E, Perrin, Richard J, Gordon, Brian A, Benzinger, Tammie L S, Grant, Elizabeth, Fagan, Anne M, Harari, Oscar, Cruchaga, Carlos, Holtzman, David M, Morris, John C

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