In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms von Lin, Chao, Lin, Kai, Luong, Yu-Ping, Rao, B Govinda, Wei, Yun-Yi, Brennan, Debra L, Fulghum, John R, Hsiao, Hsun-Mei, Ma, Sue, Maxwell, John P, Cottrell, Kevin M, Perni, Robert B, Gates, Cynthia A, Kwong, Ann D

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Inhibition of Human Hepatitis B Virus Replication by AT-61, a Phenylpropenamide Derivative, Alone and in Combination with (−)β-l-2′,3′-Dideoxy-3′-Thiacytidine von King, R W, Ladner, S K, Miller, T J, Zaifert, K, Perni, R B, Conway, S C, Otto, M J

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Synthesis and Antitumor Activity of 4-Aminomethylthioxanthenone and 5-Aminomethylbenzothiopyranoindazole Derivatives von Perni, Robert B, Wentland, Mark P, Huang, Jianhua I, Powles, Ronald G, Aldous, Suzanne, Klingbeil, Kristina M, Peverly, A. Danielle, Robinson, Ronald G, Corbett, Thomas H, Jones, Julie L, Mattes, Kenneth C, Rake, James B, Coughlin, Susan A

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Phenylpropenamide derivatives as inhibitors of Hepatitis B virus replication von Perni, Robert B, Conway, Samuel C, Ladner, Stephanie K, Zaifert, Katie, Otto, Michael J, King, Robert W

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Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease von PERNI, Robert B, ALMQUIST, Susan J, HEISER, Angela, KALKERI, Gururaj, KOLACZKOWSKI, Elaine, KAI LIN, LUONG, Yu-Ping, GOVINDA RAO, B, TAYLOR, William P, THOMSON, John A, TUNG, Roger D, YUNYI WEI, BYRN, Randal A, KWONG, Ann D, CHAO LIN, CHANDORKAR, Gurudatt, CHATURVEDI, Pravin R, COURTNEY, Lawrence F, DECKER, Caroline J, DINEHART, Kirk, GATES, Cynthia A, HARBESON, Scott L

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Synthesis and Antibacterial Activity of Some Novel 1-Substituted 1,4-Dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic Acids. Potent Antistaphylococcal Agents von Reuman, Michael, Daum, Sol J, Singh, Baldev, Wentland, Mark P, Perni, Robert B, Pennock, Patrick, Carabateas, Philip M, Gruett, Monte D, Saindane, Manohar T, Dorff, Peter H, Coughlin, Susan A, Sedlock, David M, Rake, James B, Lesher, George Y

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3-Quinolinecarboxamides. A series of novel orally-active antiherpetic agents von Wentland, Mark P, Perni, Robert B, Dorff, Peter H, Brundage, R. Pauline, Castaldi, Michael J, Bailey, Thomas R, Carabateas, Philip M, Bacon, Edward R, Young, Dorothy C

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In Vitro Studies of Cross-resistance Mutations against Two Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061 von Lin, Chao, Gates, Cynthia A., Rao, B. Govinda, Brennan, Debra L., Fulghum, John R., Luong, Yu-Ping, Frantz, J. Daniel, Lin, Kai, Ma, Sue, Wei, Yun-Yi, Perni, Robert B., Kwong, Ann D.

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Cyclic Variations of 3-Quinolinecarboxamides and Effects on Antiherpetic Activity von Wentland, Mark P, Carlson, John A, Dorff, Peter H, Aldous, Suzanne C, Perni, Robert B, Young, Dorothy C, Woods, Maureen G, Kingsley, Susan D, Ryan, Kathryn A, Rosi, David, Drozd, Marion L, Dutko, Frank J

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Synthesis and bacterial DNA gyrase inhibitory properties of a spirocyclopropylquinolone derivative von Wentland, Mark P, Perni, Robert B, Dorff, Peter H, Rake, James B

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An enantioselective and highly convergent synthesis of (+)-ikarugamycin von Boeckman, Robert K, Weidner, Charles H, Perni, Robert B, Napier, James J

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Solid sorbent for sampling acrolein in air von Gold, Avram, Dube, C. E, Perni, R. B

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Anti-solid tumor efficacy and preparation of N-[[1-[[2-(diethylamino)ethyl]amino]-9-oxo-9H-thioxanthen-4-yl]methyl]methanesulfonamide (WIN 33377) and related derivatives von WENTLAND, M. P, PERNI, R. B, POWLES, R. G, HLAVAC, A. G, MATTES, K. C, CORBETT, T. H, COUGHLIN, S. A, RAKE, J. B

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Synthesis of .alpha.-substituted 1,2-benzenedimethanamines von Johnson, Robert E, Hane, Jeffrey T, Schlegel, Donald C, Perni, Robert B, Herrmann, John L, Opalka, Chester J, Carabateas, Philip M, Ackerman, James H, Swestock, John

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4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: Novel antiarrhythmic agents von Johnson, Robert E, Baizman, Eugene R, Becker, Carolyn, Bohnet, Eric A, Bell, Rebecca H, Birsner, Nancy C, Busacca, Carl A, Carabateas, Philip M, Chadwick, Christopher C

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Relationship of structure of bridged (2,6-dimethyl-4-pyridinyl)quinolones to mammalian topoisomerase II inhibition von Wentland, Mark P., Lesher, George Y., Reuman, Michael, Pilling, Garry M., Saindane, Manohar T., Perni, Robert B., Eissenstat, Michael A., Weaver, John D., Singh, Baldev, Rake, James, Coughlin, Susan A.

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Inhibition of human hepatitis B virus replication by AT-61, a phenylpropenamide derivative, alone and in combination with (-)β-l-2'3'-dideoxy-3'-thiacytidine von KING, R. W, LADNER, S. K, MILLER, T. J, ZAIFERT, K, PERNI, R. B, CONWAY, S. C, OTTO, M. J

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Amberlyst-15 as a Convenient Catalyst for Chemoselective Thioacetalization von Perni, Robert B.

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An Efficient One-Pot Synthesis of Hippuric Acid Ethyl Ester Derivatives von Conway, Samuel C., Perni, Robert B.

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The antitumor activity of novel pyrazoloquinoline derivatives von Wentland, Mark P., Aldous, Suzanne C., Gruett, Monte D., Perni, Robert B., Powles, Ronald G., Danz, Deborah W., Klingbeil, Kristina M., Peverly, A.Danielle, Robinson, Ronald G., Corbett, Thomas H., Rake, James B., Coughlin, Susan A.

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