Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models von Mancini, Andrea, Colapietro, Alessandro, Cristiano, Loredana, Rossetti, Alessandra, Mattei, Vincenzo, Gravina, Giovanni Luca, Perez-Montoyo, Héctor, Yeste-Velasco, Marc, Alfon, Jose, Domenech, Carles, Festuccia, Claudio

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Therapeutic Potential of Autophagy Modulation in Cholangiocarcinoma von Perez-Montoyo, Hector

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Neonatal Fc receptor blockade by Fc engineering ameliorates arthritis in a murine model von Patel, Dipesh A, Puig-Canto, Alberto, Challa, Dilip Kumar, Perez Montoyo, Héctor, Ober, Raimund J, Ward, E Sally

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Assessment of biological activity in RAW 264.7 cell line stimulated with lipopolysaccharide using dynamic laser speckle von González-Peña, Rolando J., Pérez-Montoyo, Héctor, Braga, Roberto A., Viana, Dimitri Campos

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The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancer von López‐Plana, Anna, Fernández‐Nogueira, Patricia, Muñoz‐Guardiola, Pau, Solé‐Sánchez, Sònia, Megías‐Roda, Elisabet, Pérez‐Montoyo, Héctor, Jauregui, Patricia, Yeste‐Velasco, Marc, Gómez‐Ferreria, Mariana, Erazo, Tatiana, Ametller, Elisabet, Recalde‐Percaz, Leire, Moragas‐Garcia, Núria, Noguera‐Castells, Aleix, Mancino, Mario, Morán, Teresa, Nadal, Ernest, Alfón, José, Domènech, Carles, Gascon, Pere, Lizcano, Jose M., Fuster, Gemma, Bragado, Paloma

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Therapeutic potential of the new TRIB3-mediated cell autophagy anticancer drug ABTL0812 in endometrial cancer von Felip, Isidre, Moiola, Cristian Pablo, Megino-Luque, Cristina, Lopez-Gil, Carlos, Cabrera, Silvia, Solé-Sánchez, Sonia, Muñoz-Guardiola, Pau, Megias-Roda, Elisabet, Pérez-Montoyo, Héctor, Alfon, José, Yeste-Velasco, Marc, Santacana, María, Dolcet, Xavier, Reques, Armando, Oaknin, Ana, Rodríguez-Freixinos, Victor, Lizcano, José Miguel, Domènech, Carles, Gil-Moreno, Antonio, Matias-Guiu, Xavier, Colas, Eva, Eritja, Nuria

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Abstract 1805: ABTL0812, a Phase 2 clinical stage pro-autophagy anticancer drug exhibits immunomodulatory effects that modify tumor microenvironment in pancreatic cancer models von Yoldi, Guillermo, Munoz-Guardiola, Pau, Megias, Elisabet, Perez-Montoyo, Hector, Yeste-Velasco, Marc, Alfon, Jose, Domenech, Carles, Lizcano, Jose Miguel

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Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis von Challa, Dilip K, Wang, Xiaoli, Montoyo, Héctor Pérez, Velmurugan, Ramraj, Ober, Raimund J, Ward, E Sally

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Abstract 1234: The anticancer drug ABTL0812 induces cancer cell death by impairing Akt/mTORC1 axis and inducing ER stress-mediated cytotoxic autophagy von Muñoz-Guardiola, Pau, Casas, Josefina, Megías-Roda, Elisabet, Perez-Montoyo, Hector, Solé-Sánchez, Sonia, Yeste-Velasco, Marc, Erazo, Tatiana, Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Yoldi, Guillermo, Muñoz-Pinedo, Cristina, Segura, Miguel F., Alfon, Jose, Fabriàs, Gemma, Velasco, Guillermo, Domenech, Carles, Lizcano, Jose M.

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Abstract 4389: Therapeutic opportunities of RANK pathway in breast cancer von Perez Montoyo, Hector, Gomez Miragaya, Jorge, Trinidad, Eva M., Martinez-Aranda, Antonio, Soler Monso, Maria Teresa, Petit, Anna, Sierra, Angels, Gonzalez Suarez, Eva

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ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurr... von Pérez-Fidalgo, Alejandro, Leary, Alexandra, Estévez-García, Purificación, Sabatier, Renaud, Ray-Coquard, Isabelle, Romeo, Margarita, Barretina Ginesta, Maria Pilar, Gil Martin, Marta, Garralda, Elena, Bosch Barrera, Joaquim, Moran, Teresa, Martin-Martorell, Paloma, Nadal, Ernest, Gascón, Pere, Rodon, Jordi, Lizcano, José Miguel, Muñoz Guardiola, Pau, Fierro-Durán, Gemma, Pedrós-Gámez, Oriol, Pérez-Montoyo, Hector, Yeste Velasco, Marc, Cortal, Marc, Pérez-Campos, Antonio, Alfón, José, Domènech, Carles, Oaknin, Ana

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Cancer network activity associated with therapeutic response and synergism von Serra-Musach, Jordi, Mateo, Francesca, Capdevila-Busquets, Eva, de Garibay, Gorka Ruiz, Zhang, Xiaohu, Guha, Raj, Thomas, Craig J, Grueso, Judit, Villanueva, Alberto, Jaeger, Samira, Heyn, Holger, Vizoso, Miguel, Pérez, Hector, Cordero, Alex, Gonzalez-Suarez, Eva, Esteller, Manel, Moreno-Bueno, Gema, Tjärnberg, Andreas, Lázaro, Conxi, Serra, Violeta, Arribas, Joaquín, Benson, Mikael, Gustafsson, Mika, Ferrer, Marc, Aloy, Patrick, Pujana, Miquel Àngel

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Phase 2 clinical trial of the proautophagic drug ABTL0812 combined with paclitaxel and carboplatin in first-line patients with advanced squamous non-small cell lung carcinoma von Bosch-Barrera, Joaquim, Moran, Teresa, Estévez-García, Purificación, Martín-Martorell, Paloma, Sabatier, Renaud, Nadal, Ernest, Lizcano, Jose M., Pedrós-Gámez, Oriol, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Domenech, Carles, Alfon, Jose Alberto

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Correction: ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with adv... von Leary, Alexandra, Estévez-García, Purificación, Sabatier, Renaud, Ray-Coquard, Isabelle, Romeo, Margarita, Barretina-Ginesta, Pilar, Gil-Martin, Marta, Garralda, Elena, Bosch-Barrera, Joaquim, Morán, Teresa, Martin-Martorell, Paloma, Nadal, Ernest, Gascón, Pere, Rodon, Jordi, Lizcano, Jose M, Muñoz-Guardiola, Pau, Fierro-Durán, Gemma, Pedrós-Gámez, Oriol, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Cortal, Marc, Pérez-Campos, Antonio, Alfon, Jose, Domenech, Carles, Pérez-Fidalgo, Alejandro, Oaknin, Ana

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Resistance to taxanes in triple negative breast cancer associates with the dynamics of a CD49f+ tumor initiating population von Gómez Miragaya, Jorge, Palafox Sánchez, Marta, Paré, Laia, Yoldi, Guillermo, Ferrer, Irene, Vila, Sergi, Galván, Patricia, Pellegrini, Pasquale, Pérez-Montoyo, Hector, Igea, Ana, Muñoz Moruno, Purificación, Esteller, Manel, Nebreda, Àngel R, Urruticoechea Ribate, Ander, Morilla, Idoia, Pernas, Sònia, Climent, Fina, Soler, María Teresa, Petit, Anna, Serra, Violeta, Prat Aparicio, Aleix, González Suárez, Eva

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Cancer network activity associated with therapeutic response and synergism von Serra-Musach, Jordi, Mateo González, Francesca, Capdevila Busquets, Eva, Ruiz de Garibay, Gorka, Zhang, Xiaohu, Guha, Raj, Thomas, Craig J, Grueso, Judit, Villanueva Garatachea, Alberto, Jaeger, Samira, Heyn, Holger, Vizoso, Miguel, Pérez-Montoyo, Hector, Cordero, Alex, González Suárez, Eva, Esteller, Manel, Moreno-Bueno, Gema, Tjärnberg, Andreas, Lázaro García, Conxi, Serra Elizalde, Violeta, Arribas, Joaquín V. (Vicente), Benson, Mikael, Gustafsson, Mika, Ferrer, Marc, Aloy, Patrick, 1972, Pujana Genestar, M. Ángel

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Cancer network activity associated with therapeutic response and synergism von Serra-Musach, Jordi, Mateo González, Francesca, Capdevila Busquets, Eva, Ruiz de Garibay, Gorka, Zhang, Xiaohu, Guha, Raj, Thomas, Craig J, Grueso, Judit, Villanueva Garatachea, Alberto, Jaeger, Samira, Heyn, Holger, Vizoso, Miguel, Pérez-Montoyo, Hector, Cordero, Alex, González Suárez, Eva, Esteller, Manel, Moreno-Bueno, Gema, Tjärnberg, Andreas, Lázaro García, Conxi, Serra, Violeta, Arribas, Joaquín V. (Vicente), Benson, Mikael, Gustafsson, Mika, Ferrer, Marc, Aloy, Patrick, 1972, Pujana Genestar, M. Ángel

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Development of TRIB3 as a novel preclinical and clinical pharmacodynamic biomarker for ABTL0812 von Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Solé-Sánchez, Sònia, Bragado, Paloma, Colàs-Ortega, Eva, Eritja, Nuria, Lopez-Plana, Anna, Fernandez-Nogueira, Patricia, Muñoz-Guardiola, Pau, Megías-Roda, Elisabet, Moiola, Cristian, Felip, Isidre, Nadal-Alforja, Ernest, Gil Martin, Marta, Romeo, Margarita, Moran, Teresa, Gil-Moreno, Antonio, Matias-Guiu, Xavier, Domenech, Carles, Lizcano, Jose M

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A PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF A CANCER von PEREZ MONTOYO, HECTOR, MUNOZ GUARDIOLA, PAU, YOLDI SALINAS, GUILLERMO, PARIS-CODERCH, LAIA, DOMENECH GARCIA, CARLES, FESTUCCIA, CLAUDIO, YESTE-VELASCO, MARC, LIZCANO DE LA VEGA, JOSE MIGUEL, ALFON CORIAT, JOSE ALBERTO, SEGURA GUINARD, MIGUEL FRANCISCO

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FcRn blockade by Fc engineering ameliorates arthritis in a murine model von Patel, Dipesh A., Cantó, Alberto Puig, Challa, Dilip Kumar, Montoyo, Héctor Pérez, Ober, Raimund J., Ward, E. Sally

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