Dual Allosteric Inhibition of SHP2 Phosphatase von Fodor, Michelle, Price, Edmund, Wang, Ping, Lu, Hengyu, Argintaru, Andreea, Chen, Zhouliang, Glick, Meir, Hao, Huai-Xiang, Kato, Mitsunori, Koenig, Robert, LaRochelle, Jonathan R, Liu, Gang, McNeill, Eric, Majumdar, Dyuti, Nishiguchi, Gisele A, Perez, Lawrence B, Paris, Gregory, Quinn, Christopher M, Ramsey, Timothy, Sendzik, Martin, Shultz, Michael David, Williams, Sarah L, Stams, Travis, Blacklow, Stephen C, Acker, Michael G, LaMarche, Matthew J

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Synthesis and Enzymatic Studies of Bisubstrate Analogues for Farnesyl Diphosphate Synthase von Ramamoorthy, Gurusankar, Pugh, Mark L, Tian, Bo-Xue, Phan, Richard M, Perez, Lawrence B, Jacobson, Matthew P, Poulter, C. Dale

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N-Hydroxy-3-phenyl-2-propenamides as Novel Inhibitors of Human Histone Deacetylase with in Vivo Antitumor Activity:  Discovery of (2E)-N-Hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol... von Remiszewski, Stacy W, Sambucetti, Lidia C, Bair, Kenneth W, Bontempo, John, Cesarz, David, Chandramouli, Nagarajan, Chen, Ru, Cheung, Min, Cornell-Kennon, Susan, Dean, Karl, Diamantidis, George, France, Dennis, Green, Michael A, Howell, Kobporn Lulu, Kashi, Rina, Kwon, Paul, Lassota, Peter, Martin, Mary S, Mou, Yin, Perez, Lawrence B, Sharma, Sushil, Smith, Troy, Sorensen, Eric, Taplin, Francis, Trogani, Nancy, Versace, Richard, Walker, Heather, Weltchek-Engler, Susan, Wood, Alexander, Wu, Arthur, Atadja, Peter

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Second-Site NMR Screening with a Spin-Labeled First Ligand von Jahnke, Wolfgang, Perez, Lawrence B, Paris, C. Gregory, Strauss, André, Fendrich, Gabriele, Nalin, Carlo M

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The Synthesis of a Novel Inhibitor of B-Raf Kinase von Denni-Dischert, Donatienne, Marterer, Wolfgang, Bänziger, Markus, Yusuff, Naeem, Batt, David, Ramsey, Tim, Geng, Peng, Michael, Walter, Wang, Run-Ming B, Taplin, Francis, Versace, Richard, Cesarz, David, Perez, Lawrence B

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N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: Discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-... von REMISZEWSKI, Stacy W, SAMBUCETTI, Lidia C, DIAMANTIDIS, George, FRANCE, Dennis, GREEN, Michael A, HOWELL, Kobporn Lulu, KASHI, Rina, KWON, Paul, LASSOTA, Peter, MARTIN, Mary S, YIN MOU, PEREZ, Lawrence B, BAIR, Kenneth W, SHARMA, Sushil, SMITH, Troy, SORENSEN, Eric, TAPLIN, Francis, TROGANI, Nancy, VERSACE, Richard, WALKER, Heather, WELTCHEK-ENGLER, Susan, WOOD, Alexander, WU, Arthur, BONTEMPO, John, ATADJA, Peter, CESARZ, David, CHANDRAMOULI, Nagarajan, RU CHEN, MIN CHEUNG, CORNELL-KENNON, Susan, DEAN, Karl

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Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases von Chen, Ying-Nan P., LaMarche, Matthew J., Chan, Ho Man, Fekkes, Peter, Garcia-Fortanet, Jorge, Acker, Michael G., Antonakos, Brandon, Chen, Christine Hiu-Tung, Chen, Zhouliang, Cooke, Vesselina G., Dobson, Jason R., Deng, Zhan, Fei, Feng, Firestone, Brant, Fodor, Michelle, Fridrich, Cary, Gao, Hui, Grunenfelder, Denise, Hao, Huai-Xiang, Jacob, Jaison, Ho, Samuel, Hsiao, Kathy, Kang, Zhao B., Karki, Rajesh, Kato, Mitsunori, Larrow, Jay, La Bonte, Laura R., Lenoir, Francois, Liu, Gang, Liu, Shumei, Majumdar, Dyuti, Meyer, Matthew J., Palermo, Mark, Perez, Lawrence, Pu, Minying, Price, Edmund, Quinn, Christopher, Shakya, Subarna, Shultz, Michael D., Slisz, Joanna, Venkatesan, Kavitha, Wang, Ping, Warmuth, Markus, Williams, Sarah, Yang, Guizhi, Yuan, Jing, Zhang, Ji-Hu, Zhu, Ping, Ramsey, Timothy, Keen, Nicholas J., Sellers, William R., Stams, Travis, Fortin, Pascal D.

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Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer von LaMarche, Matthew J, Acker, Michael, Argintaru, Andreea, Bauer, Daniel, Boisclair, Julie, Chan, Homan, Chen, Christine Hiu-Tung, Chen, Ying-Nan, Chen, Zhouliang, Deng, Zhan, Dore, Michael, Dunstan, David, Fan, Jianmei, Fekkes, Peter, Firestone, Brant, Fodor, Michelle, Garcia-Fortanet, Jorge, Fortin, Pascal D, Fridrich, Cary, Giraldes, John, Glick, Meir, Grunenfelder, Denise, Hao, Huia-Xiang, Hentemann, Martin, Ho, Samuel, Jouk, Andriana, Kang, Zhao B, Karki, Rajesh, Kato, Mitsunori, Keen, Nick, Koenig, Robert, LaBonte, Laura R, Larrow, Jay, Liu, Gang, Liu, Shumei, Majumdar, Dyuti, Mathieu, Simon, Meyer, Matthew J, Mohseni, Morvarid, Ntaganda, Rukundo, Palermo, Mark, Perez, Lawrence, Pu, Minying, Ramsey, Timothy, Reilly, John, Sarver, Patrick, Sellers, William R, Sendzik, Martin, Shultz, Michael D, Slisz, Joanna, Slocum, Kelly, Smith, Troy, Spence, Stanley, Stams, Travis, Straub, Christopher, Tamez, Victoriano, Toure, Bakary-Barry, Towler, Christopher, Wang, Ping, Wang, Hongyun, Williams, Sarah L, Yang, Fan, Yu, Bing, Zhang, Ji-Hu, Zhu, Suzanne

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HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS von BAIR KENNETH WALTER, SAMBUCETTI LIDIA, GREEN MICHAEL A, VERSACE RICHARD WILLIAM, PEREZ LAWRENCE B, REMISZEWSKI STACY W, SHARMA SUSHIL KUMAR

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COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS von BROOKS CLINTON, LOREN JON, LIU XIAODONG, WRONA WOJCIECH, REVESZ LASZLO, PEREZ LAWRENCE B, CHIANELLI DONATELLA, NABAKKA JULIET, MANLEY PAUL W, LI XIAOLIN, MOLTENI VALENTINA, BREITENSTEIN WERNER

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COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS von BROOKS CLINTON, LOREN JON, LIU XIAODONG, WRONA WOJCIECH, REVESZ LASZLO, PEREZ LAWRENCE B, CHIANELLI DONATELLA, NABAKKA JULIET, MANLEY PAUL W, LI XIAOLIN, MOLTENI VALENTINA, BREITENSTEIN WERNER

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Hydroxamate derivatives useful as deacetylase inhibitors and pharmaceutical compositions containing them von BAIR KENNETH WALTER MOUNTAIN LAKES, GREEN MICHAEL A. EASTON, PEREZ LAWRENCE B. HACKETTSTOWN, SHARMA SUSHIL KUMAR WEST ORANGE, VERSACE RICHARD WILLIAM WANAQUE, REMISZEWSKI STACY W. WASHINGTON TOWNSHIP, SAMBUCETTI LIDIA PACIFICA

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N-Hydroxylated amide derivatives and pharmaceutical compositions comprising thereof von BAIR KENNETH WALTER, SAMBUCETTI LIDIA, GREEN MICHAEL A, VERSACE RICHARD WILLIAM, PEREZ LAWRENCE B, REMISZEWSKI STACY W, SHARMA SUSHIL KUMAR

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n-hidróxi-3-[4-[[[2-(2-metil-1h-indol-3-il)etil]-amino]metil]fenil]-2e-2-propenamida, composição farmacêutica compreendendo o mesmo e uso von Michael A. Green, Lidia Sambucetti, Richard William Versace, Kenneth Walter Bair, Sushil Kumar Sharma, Lawrence B. Perez, Stacy W. Remiszewski

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HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS von SHARMA, SUSHIL KUMAR, GREEN, MICHAEL A, SAMBUCETTI, LIDIA, BAIR, KENNETH WALTER, REMISZEWSKI, STACY W, PEREZ, LAWRENCE B, VERSACE, RICHARD WILLIAM

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Compounds and compositions as protein kinase inhibitors von LOREN, JON, LI, XIAOLIN, LIU, XIAODONG, MANLEY, PAUL W, WRONA, WOJCIECH, BREITENSTEIN, WERNER, CHIANELLI, DONATELLA, PEREZ, LAWRENCE B, BROOKS, CLINTON, NABAKKA, JULIET, MOLTENI, VALENTINA, REVESZ, LASZLO

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COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INIBITORS von REVESZ,LASZLO, CHIANELLI,DONATELLA, BREITEINSTEI, LOREN,JON, MANLEY,PAUL W, LI,XIAOLIN, PEREZ,LAWRENCE B, BROOKS,CLINTON, MOLTENI,VALENTINA, WRONA,WOJCIECH, NABAKKA,JULIET, LIU,XIAODONG

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Deacetylase inhibitors von GREEN, MICHA4EL A, SAMBUCETTI, LIDIA+, BAIR, KENNETH WALTER, REMISZEWSKI, STACY W, PEREZ, LAWRENCE B

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HYDROXAMATE DERIVATIVES USEFUL AS DEACETYLASE INHIBITORS von BAIR KENNETH WALTER, SAMBUCETTI LIDIA, GREEN MICHAEL A, VERSACE RICHARD WILLIAM, PEREZ LAWRENCE B, REMISZEWSKI STACY W, SHARMA SUSHIL KUMAR

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COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS von BROOKS CLINTON, LOREN JON, MANLEY PAUL WILLIAM, LIU XIAODONG, WRONA WOJCIECH, REVESZ LASZLO, PEREZ LAWRENCE B, CHIANELLI DONATELLA, NABAKKA JULIET, LI XIAOLIN, MOLTENI VALENTINA, BREITENSTEIN WERNER

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