Quantification and clinical validation of the selective MET kinase inhibitor DO-2 and its metabolites DO-5 and M3 in human plasma von Sikkema, Barend J., Mathijssen, Ron H.J., Robbrecht, Debbie G.J., Perera, Timothy P.S., Koolen, Stijn L.W., de Bruijn, Peter

Volltext

Abstract C152: Preclinical and emerging Phase 1 study data indicates that novel deuterated MET kinase inhibitor DO-2 mitigates the side effects seen with current approved MET kinas... von Perera, Timothy P.S., Mevellec, Laurence, Prenen, Hans, Dekeyser, Bernd, Robbrecht, Debbie, Bins, Sander, Sikkema, Barend, de Bruijn, Peter, Machiels, Jean-Pascal, Galot, Rachel, Briol, Damien, Knight, Richard, Loryan, Irena, Hu, Yang, Wastelin, Florence, Verweij, Jaap

Volltext

5-Membered Annelated Heterocyclic Pyrimidines As Kinase Inhibitors von LARDEAU DELPHINE Y.R, TEN HOLTE PETER, PERERA TIMOTHY P.S, LACRAMPE JEAN F.A, LIGNY YANNICK A.E, FREYNE EDDY J.E, LAVRIJSSEN TOM

Volltext bestellen

Macrocyclic quinazoline derivatives as antiproliferative agents von FREYNE EDDY JEAN E, PERERA TIMOTHY P.S, DIELS GASTON S.M, WILLEMS MARC, EMBRECHTS WERNER C.J, BUIJNSTERS PETER JACOBUS J.A

Volltext bestellen

PYRIDO- AND PYRIMIDOPYRIMIDINE DERIVATIVES AS ANTI-PROLIFERATIVE AGENTS von PONCELET, V.S, WILLEMS, MARC, STORCK, PIERRE H, FREYNE, EDDY JEAN E, VAN EMELEN, KRISTOF, EMBRECHTS, WERNER C.J, BUIJNSTERS, P.J.J.A, PERERA, TIMOTHY P.S

Volltext bestellen

Pyrido-and pyrimidopyrimidine derivatives as anti-profilerative agents von STORCK PIERRE H, PERERA TIMOTHY P.S, PONCELET VIRGINIE S, BUIJNSTERS PETER JACOBUS JOHNNES A, WILLEMS MARC, VAN EMELEN KRISTOF, EMBRECHTS WERNER C.J, FREYNE EDDY J.E

Volltext bestellen

PYRIDO- AND PYRIMIDOPYRIMIDINE DERIVATIVES AS ANTI-PROLIFERATIVE AGENTS von PONCELET, V.S, WILLEMS, MARC, STORCK, PIERRE H, FREYNE, EDDY JEAN E, VAN EMELEN, KRISTOF, EMBRECHTS, WERNER C.J, BUIJNSTERS, P.J.J.A, PERERA, TIMOTHY P.S

Volltext bestellen

PYRIDO- UND PYRIMIDOPYRIMIDINDERIVATE ALS ANTI-PROLIFERATIVE MITTEL von PONCELET, V.S, WILLEMS, MARC, STORCK, PIERRE H, FREYNE, EDDY JEAN E, VAN EMELEN, KRISTOF, EMBRECHTS, WERNER C.J, BUIJNSTERS, P.J.J.A, PERERA, TIMOTHY P.S

Volltext bestellen

PYRIDO- UND PYRIMIDOPYRIMIDINDERIVATE ALS ANTI- PROLIFERATIVE MITTEL von PONCELET, V.S, WILLEMS, MARC, STORCK, PIERRE H, FREYNE, EDDY JEAN E, VAN EMELEN, KRISTOF, EMBRECHTS, WERNER C.J, BUIJNSTERS, P.J.J.A, PERERA, TIMOTHY P.S

Volltext bestellen

COMPUESTOS DERIVADOS DE QUINAZOLINA, INHIBIDOR DE QUINASA; PROCESO DE PREPARACION; COMPUESTOS INTERMEDIARIOS; COMPOSICION FARMACEUTICA; Y SU USO PARA PREPARAR UN MEDICAMENTO PARA T... von FREYNE EDDY J., WILLEMS MARC, DIELS GASTON S.M., EMBRECHTS WER-NER C.J., PERERA TIMOTHY P.S., BUIJNSTERSPETER J.J.A.:HOLTE P

Volltext bestellen