Can ‘humanized’ mice improve drug development in the 21st century? von Peltz, Gary

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Can Humanized Mice Predict Drug "Behavior" in Humans? von Xu, Dan, Peltz, Gary

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Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids von Marsee, Ary, Roos, Floris J.M., Verstegen, Monique M.A., Marsee, Ary, Roos, Floris, Verstegen, Monique, Clevers, Hans, Vallier, Ludovic, Takebe, Takanori, Huch, Meritxell, Peng, Weng Chuan, Forbes, Stuart, Lemaigre, Frédéric, de Koning, Eelco, Gehart, Helmuth, van der Laan, Luc, Spee, Bart, Boj, Sylvia, Baptista, Pedro, Schneeberger, Kerstin, Soroka, Carol, Heim, Markus, Nuciforo, Sandro, Zaret, Kenneth, Saito, Yoshimasa, Lutolf, Matthias, Cardinale, Vincenzo, Simons, Ben, van IJzendoorn, Sven, Kamiya, Akihide, Chikada, Hiromi, Wang, Shuyong, Mun, Seon Ju, Son, Myung Jin, Onder, Tamer Tevfik, Boyer, James, Sato, Toshiro, Georgakopoulos, Nikitas, Meneses, Andre, Broutier, Laura, Boulter, Luke, Grün, Dominic, IJzermans, Jan, Artegiani, Benedetta, van Boxtel, Ruben, Kuijk, Ewart, Carpino, Guido, Peltz, Gary, Banales, Jesus, Man, Nancy, Aloia, Luigi, LaRusso, Nicholas, George, Gregory, Rimland, Casey, Yeoh, George, Grappin-Botton, Anne, Stange, Daniel, Prior, Nicole, Tirnitz-Parker, Janina E.E., Andersson, Emma, Braconi, Chiara, Hannan, Nicholas, Lu, Wei-Yu, Strom, Stephen, Sancho-Bru, Pau, Ogawa, Shinichiro, Corbo, Vincenzo, Lancaster, Madeline, Hu, Huili, Fuchs, Sabine, Hendriks, Delilah, Gehart, Helmuth, de Koning, Eelco, Lemaigre, Frédéric, Forbes, Stuart J., Peng, Weng Chuan, Huch, Meritxell, Takebe, Takanori, Vallier, Ludovic, Clevers, Hans, van der Laan, Luc J.W., Spee, Bart

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What Have We Learned (or Expect to) From Analysis of Murine Genetic Models Related to Substance Use Disorders? von Peltz, Gary, Tan, Yalun

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A human multi-lineage hepatic organoid model for liver fibrosis von Guan, Yuan, Enejder, Annika, Wang, Meiyue, Fang, Zhuoqing, Cui, Lu, Chen, Shih-Yu, Wang, Jingxiao, Tan, Yalun, Wu, Manhong, Chen, Xinyu, Johansson, Patrik K., Osman, Issra, Kunimoto, Koshi, Russo, Pierre, Heilshorn, Sarah C., Peltz, Gary

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Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design von Smith, Justin D, Suresh, Sundari, Schlecht, Ulrich, Wu, Manhong, Wagih, Omar, Peltz, Gary, Davis, Ronald W, Steinmetz, Lars M, Parts, Leopold, St Onge, Robert P

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The reconstituted ‘humanized liver’ in TK-NOG mice is mature and functional von Hasegawa, Masami, Kawai, Kenji, Mitsui, Tetsuya, Taniguchi, Kenji, Monnai, Makoto, Wakui, Masatoshi, Ito, Mamoru, Suematsu, Makoto, Peltz, Gary, Nakamura, Masato, Suemizu, Hiroshi

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The phosphatidylethanolamine biosynthesis pathway provides a new target for cancer chemotherapy von Guan, Yuan, Chen, Xinyu, Wu, Manhong, Zhu, Wan, Arslan, Ahmed, Takeda, Saori, Nguyen, Mindie H., Majeti, Ravindra, Thomas, Dan, Zheng, Ming, Peltz, Gary

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Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity von Sorge, Robert E, Trang, Tuan, Dorfman, Ruslan, Smith, Shad B, Beggs, Simon, Ritchie, Jennifer, Austin, Jean-Sebastien, Zaykin, Dmitri V, Meulen, Heather Vander, Costigan, Michael, Herbert, Teri A, Yarkoni-Abitbul, Merav, Tichauer, David, Livneh, Jessica, Gershon, Edith, Zheng, Ming, Tan, Keith, John, Sally L, Slade, Gary D, Jordan, Joanne, Woolf, Clifford J, Peltz, Gary, Maixner, William, Diatchenko, Luda, Seltzer, Ze'ev, Salter, Michael W, Mogil, Jeffrey S

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P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of duchenne muscular dystrophy von Sinadinos, Anthony, Young, Christopher N J, Al-Khalidi, Rasha, Teti, Anna, Kalinski, Paweł, Mohamad, Shafini, Floriot, Léonore, Henry, Tiphaine, Tozzi, Gianluca, Jiang, Taiwen, Wurtz, Olivier, Lefebvre, Alexis, Shugay, Mikhail, Tong, Jie, Vaudry, David, Arkle, Stephen, doRego, Jean-Claude, Górecki, Dariusz C

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GSEApy: a comprehensive package for performing gene set enrichment analysis in Python von Fang, Zhuoqing, Liu, Xinyuan, Peltz, Gary

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The Effect of Population Structure on Murine Genome-Wide Association Studies von Wang, Meiyue, Fang, Zhuoqing, Yoo, Boyoung, Bejerano, Gill, Peltz, Gary

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Human hepatic organoids for the analysis of human genetic diseases von Guan, Yuan, Xu, Dan, Garfin, Phillip M, Ehmer, Ursula, Hurwitz, Melissa, Enns, Greg, Michie, Sara, Wu, Manhong, Zheng, Ming, Nishimura, Toshihiko, Sage, Julien, Peltz, Gary

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Analysis of structural variation among inbred mouse strains von Arslan, Ahmed, Fang, Zhuoqing, Wang, Meiyue, Tan, Yalun, Cheng, Zhuanfen, Chen, Xinyu, Guan, Yuan, J Pisani, Laura, Yoo, Boyoung, Bejerano, Gill, Peltz, Gary

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Transcription factor p73 regulates Th1 differentiation von Ren, Min, Kazemian, Majid, Zheng, Ming, He, JianPing, Li, Peng, Oh, Jangsuk, Liao, Wei, Li, Jessica, Rajaseelan, Jonathan, Kelsall, Brian L., Peltz, Gary, Leonard, Warren J.

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Fialuridine induces acute liver failure in chimeric TK-NOG mice: a model for detecting hepatic drug toxicity prior to human testing von Xu, Dan, Nishimura, Toshi, Nishimura, Sachiko, Zhang, Haili, Zheng, Ming, Guo, Ying-Ying, Masek, Marylin, Michie, Sara A, Glenn, Jeffrey, Peltz, Gary

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Profiling of ARDS pulmonary edema fluid identifies a metabolically distinct subset von Rogers, Angela J, Contrepois, Kévin, Wu, Manhong, Zheng, Ming, Peltz, Gary, Ware, Lorraine B, Matthay, Michael A

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Optimizing a therapy for opiate use disorders: Characterizing ondansetron pharmacokinetics in blood and brain von Wu, Manhong, Cheng, Zhuanfen, Le, Anthony T., Tan, Yalun, Peltz, Gary

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Engineered Matrices Enable the Culture of Human Patient‐Derived Intestinal Organoids von Hunt, Daniel R., Klett, Katarina C., Mascharak, Shamik, Wang, Huiyuan, Gong, Diana, Lou, Junzhe, Li, Xingnan, Cai, Pamela C., Suhar, Riley A., Co, Julia Y., LeSavage, Bauer L., Foster, Abbygail A., Guan, Yuan, Amieva, Manuel R., Peltz, Gary, Xia, Yan, Kuo, Calvin J., Heilshorn, Sarah C.

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Cover Image von Guan, Yuan, Peltz, Gary

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