RNA Exosome-Regulated Long Non-Coding RNA Transcription Controls Super-Enhancer Activity von Pefanis, Evangelos, Wang, Jiguang, Rothschild, Gerson, Lim, Junghyun, Kazadi, David, Sun, Jianbo, Federation, Alexander, Chao, Jaime, Elliott, Oliver, Liu, Zhi-Ping, Economides, Aris N., Bradner, James E., Rabadan, Raul, Basu, Uttiya

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Noncoding RNA transcription targets AID to divergently transcribed loci in B cells von Pefanis, Evangelos, Wang, Jiguang, Rothschild, Gerson, Lim, Junghyun, Chao, Jaime, Rabadan, Raul, Economides, Aris N., Basu, Uttiya

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Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells von Laffleur, Brice, Lim, Junghyun, Zhang, Wanwei, Chen, Yiyun, Pefanis, Evangelos, Bizarro, Jonathan, Batista, Carolina R., Wu, Lijing, Economides, Aris N., Wang, Jiguang, Basu, Uttiya

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Tissue-specific activation of gene expression by the Synergistic Activation Mediator (SAM) CRISPRa system in mice von Hunt, Charleen, Hartford, Suzanne A., White, Derek, Pefanis, Evangelos, Hanna, Timothy, Herman, Clarissa, Wiley, Jarrell, Brown, Heather, Su, Qi, Xin, Yurong, Voronin, Dennis, Nguyen, Hien, Altarejos, Judith, Crosby, Keith, Haines, Jeffery, Cancelarich, Sarah, Drummond, Meghan, Moller-Tank, Sven, Malpass, Ryan, Buckley, Jacqueline, del Pilar Molina-Portela, Maria, Droguett, Gustavo, Frendewey, David, Chiao, Eric, Zambrowicz, Brian, Gong, Guochun

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The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates von Basu, Uttiya, Meng, Fei-Long, Keim, Celia, Grinstein, Veronika, Pefanis, Evangelos, Eccleston, Jennifer, Zhang, Tingting, Myers, Darienne, Wasserman, Caitlyn R., Wesemann, Duane R., Januszyk, Kurt, Gregory, Richard I., Deng, Haiteng, Lima, Christopher D., Alt, Frederick W.

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Transcriptomics Identify CD9 as a Marker of Murine IL-10-Competent Regulatory B Cells von Sun, Jianbo, Wang, Jiguang, Pefanis, Evangelos, Chao, Jaime, Rothschild, Gerson, Tachibana, Isao, Chen, Jun Kui, Ivanov, Ivaylo I., Rabadan, Raul, Takeda, Yoshito, Basu, Uttiya

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Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry von Lim, Junghyun, Giri, Pankaj Kumar, Kazadi, David, Laffleur, Brice, Zhang, Wanwei, Grinstein, Veronika, Pefanis, Evangelos, Brown, Lewis M., Ladewig, Erik, Martin, Ophélie, Chen, Yuling, Rabadan, Raul, Boyer, François, Rothschild, Gerson, Cogné, Michel, Pinaud, Eric, Deng, Haiteng, Basu, Uttiya

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Efficient engraftment and viral transduction of human hepatocytes in an FRG rat liver humanization model von Carbonaro, Marisa, Lee, Jeffrey, Pefanis, Evangelos, Desclaux, Mathieu, Wang, Kehui, Pennington, Alexander, Huang, Hui, Mujica, Alejo, Rojas, Jose, Ally, Roxanne, Kennedy, Daniel, Brown, Michael, Rogulin, Vitaliy, Moller-Tank, Sven, Sabin, Leah, Zambrowicz, Brian, Thurston, Gavin, Li, Zhe

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The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity von Rialdi, Alexander, Hultquist, Judd, Jimenez-Morales, David, Peralta, Zuleyma, Campisi, Laura, Fenouil, Romain, Moshkina, Natasha, Wang, Zhen Zhen, Laffleur, Brice, Kaake, Robyn M., McGregor, Michael J., Haas, Kelsey, Pefanis, Evangelos, Albrecht, Randy A., Pache, Lars, Chanda, Sumit, Jen, Joanna, Ochando, Jordi, Byun, Minji, Basu, Uttiya, García-Sastre, Adolfo, Krogan, Nevan, van Bakel, Harm, Marazzi, Ivan

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Conditionals by inversion provide a universal method for the generation of conditional alleles von Economides, Aris N, Frendewey, David, Yang, Peter, Dominguez, Melissa G, Dore, Anthony T, Lobov, Ivan B, Persaud, Trikaldarshi, Rojas, Jose, McClain, Joyce, Lengyel, Peter, Droguett, Gustavo, Chernomorsky, Rostislav, Stevens, Sean, Auerbach, Wojtek, Dechiara, Thomas M, Pouyemirou, William, Cruz, Jr, Joseph M, Feeley, Kieran, Mellis, Ian A, Yasenchack, Jason, Hatsell, Sarah J, Xie, Liqin, Latres, Esther, Huang, Lily, Zhang, Yuhong, Pefanis, Evangelos, Skokos, Dimitris, Deckelbaum, Ron A, Croll, Susan D, Davis, Samuel, Valenzuela, David M, Gale, Nicholas W, Murphy, Andrew J, Yancopoulos, George D

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Genetic and functional evidence links a missense variant in B4GALT1 to lower LDL and fibrinogen von Montasser, May E, Van Hout, Cristopher V, Miloscio, Lawrence, Howard, Alicia D, Rosenberg, Avraham, Callaway, Myrasol, Shen, Biao, Li, Ning, Locke, Adam E, Verweij, Niek, De, Tanima, Ferreira, Manuel A, Lotta, Luca A, Baras, Aris, Daly, Thomas J, Hartford, Suzanne A, Lin, Wei, Mao, Yuan, Ye, Bin, White, Derek, Gong, Guochun, Perry, James A, Ryan, Kathleen A, Fang, Qing, Tzoneva, Gannie, Pefanis, Evangelos, Hunt, Charleen, Tang, Yajun, Lee, Lynn, Sztalryd-Woodle, Carole, Mitchell, Braxton D, Healy, Matthew, Streeten, Elizabeth A, Taylor, Simeon I, O'Connell, Jeffrey R, Economides, Aris N, Della Gatta, Giusy, Shuldiner, Alan R

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Multifunctional Alleles: A novel method for the generation of “All-In-One” null and conditional alleles von Pefanis, Evangelos, Schoenherr, Christopher, Persaud, Trikaldarshi, Zhang, Yuhong, Golubov, Jacquelynn, Wang, Bei, Skokos, Dimitris, Zambrowicz, Brian, Murphy, Andrew J., Economides, Aris N.

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Nuclear Proximity of Mtr4 with RNA exosome restricts DNA mutational asymmetry von Lim, Junghyun, Giri, Pankaj Kumar, Kazadi, David, Laffleur, Brice, Zhang, Wanwei, Grinstein, Veronika, Pefanis, Evangelos, Brown, Lewis M., Ladewig, Erik, Martin, Ophélie, Chen, Yuling, Rabadan, Raul, Boyer, François, Rothschild, Gerson, Cogné, Michel, Pinaud, Eric, Deng, Haiteng, Basu, Uttiya

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Transcriptional stalling in B-lymphocytes: A mechanism for antibody diversification and maintenance of genomic integrity von Sun, Jianbo, Rothschild, Gerson, Pefanis, Evangelos, Basu, Uttiya

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Conditionals by inversion provide a universal method for the generation of conditional alleles von Economides, Aris N., Frendewey, David, Yang, Peter, Dominguez, Melissa G., Dore, Anthony T., Lobov, Ivan B., Persaud, Trikaldarshi, Rojas, Jose, McClain, Joyce, Lengyel, Peter, Droguett, Gustavo, Chernomorsky, Rostislav, Stevens, Sean, Auerbach, Wojtek, DeChiara, Thomas M., Pouyemirou, William, Cruz, Joseph M., Feeley, Kieran, Mellis, Ian A., Yasenchack, Jason, Hatsell, Sarah J., Xie, LiQin, Latres, Esther, Huang, Lily, Zhang, Yuhong, Pefanis, Evangelos, Skokos, Dimitris, Deckelbaum, Ron A., Croll, Susan D., Davis, Samuel, Valenzuela, David M., Gale, Nicholas W., Murphy, Andrew J., Yancopoulos, George D.

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Transcriptomics identify CD9 as a marker of murine IL10-competent regulatory B cells von Sun, Jianbo, Wang, Jiguang, Pefanis, Evangelos, Chao, Jaime, Rothschild, Gerson, Tachibana, Isao, Chen, Jun Kui, Ivanov, Ivaylo I., Rabadan, Raul, Takeda, Yoshito, Basu, Uttiya

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TREATMENT OF MUSCLE RELATED DISORDERS WITH ANTI-HUMAN CACNG1 ANTIBODIES von STEC, Michael, KYRATSOUS, Christos, PEFANIS, Evangelos, BAIK, Andrew

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CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR KNOCKING OUT C5 von Pefanis, Evangelos, Hesse, Sarah, Morton, Lori, Hartford, Suzanne, Devalaraja-Narashimha, Kishor, Kanjolia, Arti Mahendra Prakash

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CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR KNOCKING OUT C5 von KANJOLIA, Arti, Mahendra, Prakash, HARTFORD, Suzanne, MORTON, Lori, PEFANIS, Evangelos, HESSE, Sarah, DEVALARAJA-NARASHIMHA, Kishor

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CRISPR-BASED THERAPEUTICS FOR C9ORF72 REPEAT EXPANSION DISEASE von GAGLIARDI, Anthony, SHARMA-KANNING, Aarti, SUNDARAMOORTHY, Sriramkumar, PEFANIS, Evangelos, FRENDEWEY, David

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