Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα von Wang, Yunmei, Gao, Huiyun, Shi, Can, Erhardt, Paul W., Pavlovsky, Alexander, A. Soloviev, Dmitry, Bledzka, Kamila, Ustinov, Valentin, Zhu, Liang, Qin, Jun, Munday, Adam D., Lopez, Jose, Plow, Edward, Simon, Daniel I.

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Aspartoacylase Catalytic Deficiency as the Cause of Canavan Disease: A Structural Perspective von Wijayasinghe, Yasanandana S, Pavlovsky, Alexander G, Viola, Ronald E

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Discovery and Characterization of a Novel Inhibitor of Matrix Metalloprotease-13 That Reduces Cartilage Damage in Vivo without Joint Fibroplasia Side Effects von Johnson, Adam R., Pavlovsky, Alexander G., Ortwine, Daniel F., Prior, Faith, Man, Chiu-Fai, Bornemeier, Dirk A., Banotai, Craig A., Mueller, W. Thomas, McConnell, Patrick, Yan, Chunhong, Baragi, Vijay, Lesch, Charles, Roark, W. Howard, Wilson, Michael, Datta, Kaushik, Guzman, Roberto, Han, Hyo-Kyung, Dyer, Richard D.

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Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition von Hasemann, Charles A, Ohren, Jeffrey F, Chen, Huifen, Pavlovsky, Alexander, Whitehead, Christopher, Zhang, Erli, Kuffa, Peter, Yan, Chunhong, McConnell, Patrick, Spessard, Cindy, Banotai, Craig, Mueller, W Thomas, Delaney, Amy, Omer, Charles, Sebolt-Leopold, Judith, Dudley, David T, Leung, Iris K, Flamme, Cathlin, Warmus, Joseph, Kaufman, Michael, Barrett, Stephen, Tecle, Haile

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A randomised Phase III trial of glufosfamide compared with best supportive care in metastatic pancreatic adenocarcinoma previously treated with gemcitabine von Ciuleanu, Tudor E, Pavlovsky, Alexander V, Bodoky, Gyorgy, Garin, Avgust M, Langmuir, Virginia K, Kroll, Stewart, Tidmarsh, George T

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Structure of homoserine O-acetyltransferase from Staphylococcus aureus: the first Gram-positive ortholog structure von Thangavelu, Bharani, Pavlovsky, Alexander G., Viola, Ronald

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Structure of an unusual S-adenosylmethionine synthetase from Campylobacter jejuni von Zano, Stephen P., Pavlovsky, Alexander G., Viola, Ronald E.

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Correction: Corrigendum: Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα von Wang, Yunmei, Gao, Huiyun, Shi, Can, Erhardt, Paul W., Pavlovsky, Alexander, Soloviev, Dmitry A., Bledzka, Kamila, Ustinov, Valentin, Zhu, Liang, Qin, Jun, Munday, Adam D., Lopez, Jose, Plow, Edward, Simon, Daniel I.

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The Structural Basis for Allosteric Inhibition of a Threonine-sensitive Aspartokinase von Liu, Xuying, Pavlovsky, Alexander G., Viola, Ronald E.

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Expansion of the aspartate β-semialdehyde dehydrogenase family: the first structure of a fungal ortholog von Arachea, Buenafe T., Liu, Xuying, Pavlovsky, Alexander G., Viola, Ronald E.

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Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family von Pavlovsky, Alexander G., Liu, Xuying, Faehnle, Christopher R., Potente, Nina, Viola, Ronald E.

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A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway von Pavlovsky, Alexander G., Thangavelu, Bharani, Bhansali, Pravin, Viola, Ronald E.

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Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis von SCHNUTE, Mark E, O'BRIEN, Patrick M, CARROLL, Jeffery N, PATT, William C, SHIEH, Huey S, COLLINS, Brandon, PAVLOVSKY, Alexander G, PALMQUIST, Katherine E, ASTON, Karl W, HITCHCOCK, Jeffrey, ROGERS, Michael D, MCDONALD, Joseph, NAHRA, Joe, JOHNSON, Adam R, MUNIE, Grace E, WITTWER, Arthur J, MAN, Chiu-Fai, SETTLE, Steven L, NEMIROVSKIY, Olga, VICKERY, Lillian E, AGAWAL, Arun, DYER, Richard D, SUNYER, Teresa, MORRIS, Mark, HOWARD ROARK, W, HANAU, Cathleen E, RUMINSKI, Peter G, SCHOLTEN, Jeffrey A, FLETCHER, Theresa R, HAMPER, Bruce C

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Structure−Activity Relationships and Pharmacokinetic Analysis for a Series of Potent, Systemically Available Biphenylsulfonamide Matrix Metalloproteinase Inhibitors von O'Brien, Patrick M, Ortwine, Daniel F, Pavlovsky, Alexander G, Picard, Joseph A, Sliskovic, Drago R, Roth, Bruce D, Dyer, Richard D, Johnson, Linda L, Man, Chiu Fai, Hallak, Hussein

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4-Anilino-5-carboxamido-2-pyridone Derivatives as Noncompetitive Inhibitors of Mitogen-Activated Protein Kinase Kinase von Spicer, Julie A, Rewcastle, Gordon W, Kaufman, Michael D, Black, Shannon L, Plummer, Mark S, Denny, William A, Quin, John, Shahripour, Aurash B, Barrett, Stephen D, Whitehead, Christopher E, Milbank, Jared B. J, Ohren, Jeffrey F, Gowan, Richard C, Omer, Charles, Camp, Heidi S, Esmaeil, Nadia, Moore, Kelley, Sebolt-Leopold, Judith S, Pryzbranowski, Sally, Merriman, Ronald L, Ortwine, Daniel F, Warmus, Joseph S, Flamme, Cathlin M, Pavlovsky, Alexander G, Tecle, Haile

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Structural insights into aspartoacylase deficiency in Canavan disease (769.4) von Wijayasinghe, Yasanandana, Pavlovsky, Alexander, Viola, Ronald

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Development of selective inhibitors against homoserine transacetylase ő a novel target for drug development (976.2) von Thangavelu, Bharani, Pavlovsky, Alexander, Viola, Ronald

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Development of the Composition and Technology for Production a Solid Dispersion System by Hot Melt Extrusion to Increase the Bioavailability of the Active Substance von Gusev, K. A., Maimistov, D. N., Pavlovsky, V. I., Aliev, A. R., Pavlovsky, A. V., Ivanova, O. V., Tsyrenov, D. O., Flisyuk, E. V.

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Crystal structure of human recombinant interleukin-4 at 2.25 Å resolution von Wlodaver, Alexander, Pavlovsky, Alexander, Gustchina, Alla

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Inhibitor Development Against Aspartate‐β‐Semialdehyde Dehydrogenase‐ A Novel Target for Drug Development von Thangavelu, Bharani, Pavlovsky, Alexander, Bhansali, Pravin, Viola, Ronald

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