Small molecule therapeutics for tauopathy in Alzheimer’s disease: Walking on the path of most resistance von Wang, Lisha, Bharti, Kumar, Rajnish, Pavlov, Pavel F., Winblad, Bengt

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amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae von Hansson Petersen, Camilla A, Alikhani, Nyosha, Behbahani, Homira, Wiehager, Birgitta, Pavlov, Pavel F, Alafuzoff, Irina, Leinonen, Ville, Ito, Akira, Winblad, Bengt, Glaser, Elzbieta, Ankarcrona, Maria

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Mitochondrial dysfunction in a transgenic mouse model expressing human amyloid precursor protein (APP) with the Arctic mutation von Rönnbäck, Annica, Pavlov, Pavel. F., Mansory, Mansorah, Gonze, Prisca, Marlière, Nicolas, Winblad, Bengt, Graff, Caroline, Behbahani, Homira

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Targeting Chaperone/Co-Chaperone Interactions with Small Molecules: A Novel Approach to Tackle Neurodegenerative Diseases von Wang, Lisha, Bergkvist, Liza, Kumar, Rajnish, Winblad, Bengt, Pavlov, Pavel F

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Structure-based discovery of small molecule inhibitors of FKBP51-Hsp90 protein-protein interaction von Wang, Lisha, Kumar, Rajnish, Winblad, Bengt, Pavlov, Pavel F.

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FKBP51-Hsp90 Interaction-Deficient Mice Exhibit Altered Endocrine Stress Response and Sex Differences Under High-Fat Diet von Wang, Lisha, Wojcieszak, Jakub, Kumar, Rajnish, Zhao, Zhe, Sun, Xuelian, Xie, Shaoxun, Winblad, Bengt, Pavlov, Pavel F.

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Combined x-ray crystallography and computational modeling approach to investigate the Hsp90 C-terminal peptide binding to FKBP51 von Kumar, Rajnish, Moche, Martin, Winblad, Bengt, Pavlov, Pavel F.

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Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein von Pavlov, Pavel F, Wiehager, Birgitta, Sakai, Jun, Frykman, Susanne, Behbahani, Homira, Winblad, Bengt, Ankarcrona, Maria

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Studies of Chaperone-Cochaperone Interactions using Homogenous Bead-Based Assay von Wang, Lisha, Bergkvist, Liza, Kumar, Rajnish, Winblad, Bengt, Pavlov, Pavel F

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Development of GMP‐1 a molecular chaperone network modulator protecting mitochondrial function and its assessment in fly and mice models of Alzheimer's disease von Pavlov, Pavel F., Hutter‐Paier, Birgit, Havas, Daniel, Windisch, Manfred, Winblad, Bengt

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Degradation of the Amyloid β-Protein by the Novel Mitochondrial Peptidasome, PreP von Falkevall, Annelie, Alikhani, Nyosha, Bhushan, Shashi, Pavlov, Pavel F., Busch, Katrin, Johnson, Kenneth A., Eneqvist, Therese, Tjernberg, Lars, Ankarcrona, Maria, Glaser, Elzbieta

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Mitochondrial accumulation of APP and Aβ: significance for Alzheimer disease pathogenesis von Pavlov, Pavel F., Petersen, Camilla Hansson, Glaser, Elzbieta, Ankarcrona, Maria

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In silico identification and biochemical characterization of the human dicarboxylate clamp TPR protein interaction network von Bernadotte, Alexandra, Kumar, Rajnish, Winblad, Bengt, Pavlov, Pavel F.

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Association of Omi/HtrA2 with γ-secretase in mitochondria von Behbahani, Homira, Pavlov, Pavel F., Wiehager, Birgitta, Nishimura, Takeshi, Winblad, Bengt, Ankarcrona, Maria

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Metabolism of mitochondria-associated APP von Pavlov, Pavel F

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P4-197: Regulation of HtrA2/Omi activity by the mitochondrial γ-secretase von Pavlov, Pavel F

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Development of tau targeted protein degraders for Alzheimer disease von Wang, Lisha, Kumar, Rajnish, Pavlov, Pavel F., Winblad, Bengt

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GMP‐1 and its analogues bind Cu 2+ and Zn 2+ and protect neurons against amyloid beta toxicity: Nonhuman/Lead optimization studies von Winblad, Bengt, Pavlov, Pavel F., Kumar, Rajnish

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GMP‐1 and its analogues bind Cu2+ and Zn2+ and protect neurons against amyloid beta toxicity von Winblad, Bengt, Pavlov, Pavel F., Kumar, Rajnish

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P4‐034: THERAPEUTIC TARGETING OF FKBP51 CO‐CHAPERONE FOR POTENTIAL ANTI‐TAU THERAPY FOR ALZHEIMER'S DISEASE von Winblad, Bengt, Kumar, Rajnish, Pavlov, Pavel F.

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