Tim-3 mediates T cell trogocytosis to limit antitumor immunity von Pagliano, Ornella, Morrison, Robert M, Chauvin, Joe-Marc, Banerjee, Hridesh, Davar, Diwakar, Ding, Quanquan, Tanegashima, Tokiyoshi, Gao, Wentao, Chakka, Saranya R, DeBlasio, Richelle, Lowin, Ava, Kara, Kevin, Ka, Mignane, Zidi, Bochra, Amin, Rada, Raphael, Itay, Zhang, Shuowen, Watkins, Simon C, Sander, Cindy, Kirkwood, John M, Bosenberg, Marcus, Anderson, Ana C, Kuchroo, Vijay K, Kane, Lawrence P, Korman, Alan J, Rajpal, Arvind, West, Sean M, Han, Minhua, Bee, Christine, Deng, Xiaodi, Schebye, Xiao Min, Strop, Pavel, Zarour, Hassane M

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Universal Affinity Capture Liquid Chromatography-Mass Spectrometry Assay for Evaluation of Biotransformation of Site-Specific Antibody Drug Conjugates in Preclinical Studies von Kotapati, Srikanth, Passmore, David, Yamazoe, Sayumi, Sanku, Rajesh Kishore Kumar, Cong, Qiang, Poudel, Yam B, Chowdari, Naidu S, Gangwar, Sanjeev, Rao, Chetana, Rangan, Vangipuram S, Cardarelli, Pina M, Deshpande, Shrikant, Strop, Pavel, Dollinger, Gavin, Rajpal, Arvind

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Refractive index‐based determination of detergent concentration and its application to the study of membrane proteins von Strop, Pavel, Brunger, Axel T.

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Generating Bispecific Human IgG1 and IgG2 Antibodies from Any Antibody Pair von Strop, Pavel, Ho, Wei-Hsien, Boustany, Leila M., Abdiche, Yasmina N., Lindquist, Kevin C., Farias, Santiago E., Rickert, Mathias, Appah, Charles Takeshi, Pascua, Edward, Radcliffe, Teresa, Sutton, Janette, Chaparro-Riggers, Javier, Chen, Wei, Casas, Meritxell Galindo, Chin, Sherman Michael, Wong, Oi Kwan, Liu, Shu-Hui, Vergara, German, Shelton, Dave, Rajpal, Arvind, Pons, Jaume

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Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates von Liang, Hong, Chaparro-Riggers, Javier, Strop, Pavel, Geng, Tao, Sutton, Janette E, Tsai, Daniel, Bai, Lanfang, Abdiche, Yasmina, Dilley, Jeanette, Yu, Jessica, Wu, Si, Chin, S Michael, Lee, Nicole A, Rossi, Andrea, Lin, John C, Rajpal, Arvind, Pons, Jaume, Shelton, David L

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Improved therapeutic index of an acidic pH-selective antibody von Lee, Peter S, MacDonald, Katherine G, Massi, Evan, Chew, Pamela V, Bee, Christine, Perkins, Padma, Chau, Bryant, Thudium, Kent, Lohre, Jack, Nandi, Pradyot, Deyanova, Ekaterina G, Barman, Ishita, Gudmundsson, Olafur, Dollinger, Gavin, Sproul, Tim, Engelhardt, John J, Strop, Pavel, Rajpal, Arvind

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Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies von Shcherbatko, Anatoly, Foletti, Davide, Poulsen, Kris, Strop, Pavel, Zhu, Guoyun, Hasa-Moreno, Adela, Melton Witt, Jody, Loo, Carole, Krimm, Stellanie, Pios, Ariel, Yu, Jessica, Brown, Colleen, Lee, John K., Stroud, Robert, Rajpal, Arvind, Shelton, David

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Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy von Dorywalska, Magdalena, Strop, Pavel, Melton-Witt, Jody A, Hasa-Moreno, Adela, Farias, Santiago E, Galindo Casas, Meritxell, Delaria, Kathy, Lui, Victor, Poulsen, Kris, Sutton, Janette, Bolton, Gary, Zhou, Dahui, Moine, Ludivine, Dushin, Russell, Tran, Thomas-Toan, Liu, Shu-Hui, Rickert, Mathias, Foletti, Davide, Shelton, David L, Pons, Jaume, Rajpal, Arvind

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Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates von Costa, Maria José, Kudaravalli, Jyothirmayee, Ma, Jing-Tyan, Ho, Wei-Hsien, Delaria, Kathy, Holz, Charles, Stauffer, Angela, Chunyk, Allison Given, Zong, Qing, Blasi, Eileen, Buetow, Bernard, Tran, Thomas-Toan, Lindquist, Kevin, Dorywalska, Magdalena, Rajpal, Arvind, Shelton, David L., Strop, Pavel, Liu, Shu-Hui

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1121 TAC-003, a TLR9 agonist antibody conjugate for targeted immunotherapy of Nectin-4 expressing tumors von Chen, Amy, Li, Min, Sangalang, Emma RB, Fontaine, Danielle, Chou, Tiffany, An, Mingrui, Bonacorsi, Maja, Han, Bora, Wan, Hong I, Costa, Maria Jose, Strop, Pavel

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Post-Translational Modifications and Lipid Binding Profile of Insect Cell-Expressed Full-Length Mammalian Synaptotagmin 1 von Vrljic, Marija, Strop, Pavel, Hill, Ryan C, Hansen, Kirk C, Chu, Steven, Brunger, Axel T

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The Longin SNARE VAMP7/TI-VAMP Adopts a Closed Conformation von Vivona, Sandro, Liu, Corey W., Strop, Pavel, Rossi, Valeria, Filippini, Francesco, Brunger, Axel T.

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The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity von Abdiche, Yasmina Noubia, Yeung, Yik Andy, Chaparro-Riggers, Javier, Barman, Ishita, Strop, Pavel, Chin, Sherman Michael, Pham, Amber, Bolton, Gary, McDonough, Dan, Lindquist, Kevin, Pons, Jaume, Rajpal, Arvind

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Tumor burden limits bispecific antibody efficacy through T cell exhaustion averted by concurrent cytotoxic therapy von Meermeier, Erin W, Welsh, Seth J, Sharik, Meaghen E, Du, Megan T, Garbitt, Victoria M, Riggs, Daniel L, Shi, Chang-Xin, Stein, Caleb K, Bergsagel, Marco, Chau, Bryant, Wheeler, Matthew L, Bezman, Natalie, Wang, Feng, Strop, Pavel, Bergsagel, P Leif, Chesi, Marta

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Site-specific conjugation improves therapeutic index of antibody drug conjugates with high drug loading von Strop, Pavel, Delaria, Kathy, Foletti, Davide, Witt, Jody Melton, Hasa-Moreno, Adela, Poulsen, Kris, Casas, Meritxell Galindo, Dorywalska, Magdalena, Farias, Santiago, Pios, Ariel, Lui, Victor, Dushin, Russell, Zhou, Dahui, Navaratnam, Thayalan, Tran, Thomas-Toan, Sutton, Janette, Lindquist, Kevin C, Han, Bora, Liu, Shu-Hui, Shelton, David L, Pons, Jaume, Rajpal, Arvind

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RN927C, a Site-Specific Trop-2 Antibody-Drug Conjugate (ADC) with Enhanced Stability, Is Highly Efficacious in Preclinical Solid Tumor Models von Strop, Pavel, Tran, Thomas-Toan, Dorywalska, Magdalena, Delaria, Kathy, Dushin, Russell, Wong, Oi Kwan, Ho, Wei-Hsien, Zhou, Dahui, Wu, Aidong, Kraynov, Eugenia, Aschenbrenner, Laura, Han, Bora, O'Donnell, Christopher J, Pons, Jaume, Rajpal, Arvind, Shelton, Dave L, Liu, Shu-Hui

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Integrated Approach for Characterizing Bispecific Antibody/Antigens Complexes and Mapping Binding Epitopes with SEC/MALS, Native Mass Spectrometry, and Protein Footprinting von Huang, Richard Y.-C, Wang, Feng, Wheeler, Matthew, Wang, Yun, Langish, Robert, Chau, Bryant, Dong, Jia, Morishige, Winse, Bezman, Natalie, Strop, Pavel, Rajpal, Arvind, Gudmundsson, Olafur, Chen, Guodong

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Mechanism of Action and In Vivo Efficacy of a Human-Derived Antibody against Staphylococcus aureus α-Hemolysin von Foletti, Davide, Strop, Pavel, Shaughnessy, Lee, Hasa-Moreno, Adela, Casas, Meritxell Galindo, Russell, Marcella, Bee, Christine, Wu, Si, Pham, Amber, Zeng, Zhilan, Pons, Jaume, Rajpal, Arvind, Shelton, Dave

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Mass Spectrometric Characterization of Transglutaminase Based Site-Specific Antibody–Drug Conjugates von Farias, Santiago E, Strop, Pavel, Delaria, Kathy, Galindo Casas, Meritxell, Dorywalska, Magdalena, Shelton, David L, Pons, Jaume, Rajpal, Arvind

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Production of soluble and active microbial transglutaminase in Escherichia coli for site‐specific antibody drug conjugation von Rickert, Mathias, Strop, Pavel, Lui, Victor, Melton‐Witt, Jody, Farias, Santiago Esteban, Foletti, Davide, Shelton, David, Pons, Jaume, Rajpal, Arvind

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