An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ von Banks, Alexander S., McAllister, Fiona E., Camporez, João Paulo G., Zushin, Peter-James H., Jurczak, Michael J., Laznik-Bogoslavski, Dina, Shulman, Gerald I., Gygi, Steven P., Spiegelman, Bruce M.

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Regulation of adipose tissue inflammation by interleukin 6 von Han, Myoung Sook, White, Alexis, Perry, Rachel J., Camporez, Joao-Paulo, Hidalgo, Juan, Shulman, Gerald I., Davis, Roger J.

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Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes von Perry, Rachel J., Camporez, João-Paulo G., Kursawe, Romy, Titchenell, Paul M., Zhang, Dongyan, Perry, Curtis J., Jurczak, Michael J., Abudukadier, Abulizi, Han, Myoung Sook, Zhang, Xian-Man, Ruan, Hai-Bin, Yang, Xiaoyong, Caprio, Sonia, Kaech, Susan M., Sul, Hei Sook, Birnbaum, Morris J., Davis, Roger J., Cline, Gary W., Petersen, Kitt Falk, Shulman, Gerald I.

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A controlled‐release mitochondrial protonophore reverses hypertriglyceridemia, nonalcoholic steatohepatitis, and diabetes in lipodystrophic mice von Abulizi, Abudukadier, Perry, Rachel J., Camporez, João Paulo G., Jurczak, Michael J., Petersen, Kitt Falk, Aspichueta, Patricia, Shulman, Gerald I.

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A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21 von Han, Myoung Sook, Perry, Rachel J, Camporez, João-Paulo, Scherer, Philipp E, Shulman, Gerald I, Gao, Guangping, Davis, Roger J

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Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents von Vatner, Daniel F., Goedeke, Leigh, Camporez, Joao-Paulo G., Lyu, Kun, Nasiri, Ali R., Zhang, Dongyan, Bhanot, Sanjay, Murray, Susan F., Still, Christopher D., Gerhard, Glenn S., Shulman, Gerald I., Samuel, Varman T.

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CD301b+ Mononuclear Phagocytes Maintain Positive Energy Balance through Secretion of Resistin-like Molecule Alpha von Kumamoto, Yosuke, Camporez, Joao Paulo G., Jurczak, Michael J., Shanabrough, Marya, Horvath, Tamas, Shulman, Gerald I., Iwasaki, Akiko

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The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis von Dominy, John E., Lee, Yoonjin, Jedrychowski, Mark P., Chim, Helen, Jurczak, Michael J., Camporez, Joao Paulo, Ruan, Hai-Bin, Feldman, Jessica, Pierce, Kerry, Mostoslavsky, Raul, Denu, John M., Clish, Clary B., Yang, Xiaoyong, Shulman, Gerald I., Gygi, Steven P., Puigserver, Pere

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Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance von Price, Nathan L., Singh, Abhishek K., Rotllan, Noemi, Goedeke, Leigh, Wing, Allison, Canfrán-Duque, Alberto, Diaz-Ruiz, Alberto, Araldi, Elisa, Baldán, Ángel, Camporez, Joao-Paulo, Suárez, Yajaira, Rodeheffer, Matthew S., Shulman, Gerald I., de Cabo, Rafael, Fernández-Hernando, Carlos

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17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization von Stout, Michael B, Steyn, Frederik J, Jurczak, Michael J, Camporez, Joao-Paulo G, Zhu, Yi, Hawse, John R, Jurk, Diana, Palmer, Allyson K, Xu, Ming, Pirtskhalava, Tamar, Evans, Glenda L, de Souza Santos, Roberta, Frank, Aaron P, White, Thomas A, Monroe, David G, Singh, Ravinder J, Casaclang-Verzosa, Grace, Miller, Jordan D, Clegg, Deborah J, LeBrasseur, Nathan K, von Zglinicki, Thomas, Shulman, Gerald I, Tchkonia, Tamara, Kirkland, James L

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Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice von Abulizi, Abudukadier, Vatner, Daniel F., Ye, Zhang, Wang, Yongliang, Camporez, Joao-Paulo, Zhang, Dongyan, Kahn, Mario, Lyu, Kun, Sirwi, Alaa, Cline, Gary W., Hussain, M. Mahmood, Aspichueta, Patricia, Samuel, Varman T., Shulman, Gerald I.

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Adipose glucocorticoid action influences whole‐body metabolism via modulation of hepatic insulin action von Abulizi, Abudukadier, Camporez, João-Paulo, Jurczak, Michael J., Høyer, Kasper F., Zhang, Dongyan, Cline, Gary W., Samuel, Varman T., Shulman, Gerald I., Vatner, Daniel F.

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Ectopic lipid deposition mediates insulin resistance in adipose specific 11β-hydroxysteroid dehydrogenase type 1 transgenic mice von Abulizi, Abudukadier, Camporez, João-Paulo, Zhang, Dongyan, Samuel, Varman T., Shulman, Gerald I., Vatner, Daniel F.

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Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis von Aryal, Binod, Singh, Abhishek K, Zhang, Xinbo, Varela, Luis, Rotllan, Noemi, Goedeke, Leigh, Chaube, Balkrishna, Camporez, Joao-Paulo, Vatner, Daniel F, Horvath, Tamas L, Shulman, Gerald I, Suárez, Yajaira, Fernández-Hernando, Carlos

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Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity von HENAO-MEJIA, Jorge, ELINAV, Eran, CAMPOREZ, Joao-Paulo, SHULMAN, Gerald I, GORDON, Jeffrey I, HOFFMAN, Hal M, FLAVELL, Richard A, JIN, Chengcheng, LIMING HAO, MEHAL, Wajahat Z, STROWIG, Till, THAISS, Christoph A, KAU, Andrew L, EISENBARTH, Stephanie C, JURCZAK, Michael J

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1577-P: Hepatic Steatosis and Glucose Intolerance in Liver-Specific Estrogen Receptor Alpha Knockout Mice von SUCUPIRA, FELIPE, ARAUJO, LAYANNE, PAULO CAMPOREZ, JOAO

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CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance von Cantley, Jennifer L., Yoshimura, Toru, Camporez, Joao Paulo G., Zhang, Dongyan, Jornayvaz, Francois R., Kumashiro, Naoki, Guebre-Egziabher, Fitsum, Jurczak, Michael J., Kahn, Mario, Guigni, Bias A., Serr, Julie, Hankin, Joseph, Murphy, Robert C., Cline, Gary W., Bhanot, Sanjay, Manchem, Vara Prasad, Brown, J. Mark, Samuel, Varman T., Shulman, Gerald I.

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Hepatic Mitogen-Activated Protein Kinase Phosphatase 1 Selectively Regulates Glucose Metabolism and Energy Homeostasis von Lawan, Ahmed, Zhang, Lei, Gatzke, Florian, Min, Kisuk, Jurczak, Michael J., Al-Mutairi, Mashael, Richter, Patric, Camporez, Joao Paulo G., Couvillon, Anthony, Pesta, Dominik, Roth Flach, Rachel J., Shulman, Gerald I., Bennett, Anton M.

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Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis von Perry, Rachel J, Zhang, Xian-Man, Zhang, Dongyan, Kumashiro, Naoki, Camporez, Joao-Paulo G, Cline, Gary W, Rothman, Douglas L, Shulman, Gerald I

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Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice von Camporez, João-Paulo G., Petersen, Max C., Abudukadier, Abulizi, Moreira, Gabriela V., Jurczak, Michael J., Friedman, Glenn, Haqq, Christopher M., Petersen, Kitt Falk, Shulman, Gerald I.

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