Antibody-Drug Conjugates for the Treatment of Cancer von Flygare, John A., Pillow, Thomas H., Aristoff, Paul

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Rifamycins – Obstacles and opportunities von Aristoff, Paul A, Garcia, George A, Kirchhoff, Paul D, Hollis Showalter, H.D

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New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis von Anthony, Karen G, Strych, Ulrich, Yeung, Kacheong R, Shoen, Carolyn S, Perez, Oriana, Krause, Kurt L, Cynamon, Michael H, Aristoff, Paul A, Koski, Raymond A

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A Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF) von Bai, Fengwei, Asojo, Oluwatoyin A., Cirillo, Pier, Ciustea, Mihai, Ledizet, Michel, Aristoff, Paul A., Leng, Lin, Koski, Raymond A., Powell, Thomas J., Bucala, Richard, Anthony, Karen G.

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Inhibition of mycobacterial alanine racemase activity and growth by thiadiazolidinones von Lee, Yashang, Mootien, Sara, Shoen, Carolyn, Destefano, Michelle, Cirillo, Pier, Asojo, Oluwatoyin A., Yeung, Kacheong R., Ledizet, Michel, Cynamon, Michael H., Aristoff, Paul A., Koski, Raymond A., Kaplan, Paul A., Anthony, Karen G.

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Thiadiazolidinones: A new class of alanine racemase inhibitors with antimicrobial activity against methicillin-resistant Staphylococcus aureus von Ciustea, Mihai, Mootien, Sara, Rosato, Adriana E., Perez, Oriana, Cirillo, Pier, Yeung, Kacheong R., Ledizet, Michel, Cynamon, Michael H., Aristoff, Paul A., Koski, Raymond A., Kaplan, Paul A., Anthony, Karen G.

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Oxazolidinones: a new class of antibacterials von Zurenko, Gary E, Gibson, John K, Shinabarger, Dean L, Aristoff, Paul A, Ford, Charles W, Tarpley, W.Gary

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Antibacterial Oxazolidinones Possessing a Novel C-5 Side Chain. (5R)-trans-3-[3-Fluoro-4- (1-oxotetrahydrothiopyran-4-yl)phenyl]-2- oxooxazolidine-5-carboxylic Acid Amide (PF-00422... von Poel, Toni-Jo, Thomas, Richard C, Adams, Wade J, Aristoff, Paul A, Barbachyn, Michael R, Boyer, Frederick E, Brieland, Joan, Brideau, Roger, Brodfuehrer, Joanne, Brown, Alan P, Choy, Allison L, Dermyer, Michael, Dority, Michael, Ford, Charles W, Gadwood, Robert C, Hanna, Debra, Hongliang, Cai, Huband, Michael D, Huber, Christopher, Kelly, Rose, Kim, Ji-Young, Martin, Joseph P, Pagano, Paul J, Ross, Daniel, Skerlos, Laura, Sulavik, Mark C, Zhu, Tong, Zurenko, Gary E, Prasad, J. V. N. Vara

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Structure–Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch von Vicens, Quentin, Mondragón, Estefanía, Reyes, Francis E, Coish, Philip, Aristoff, Paul, Berman, Judd, Kaur, Harpreet, Kells, Kevin W, Wickens, Phil, Wilson, Jeffery, Gadwood, Robert C, Schostarez, Heinrich J, Suto, Robert K, Blount, Kenneth F, Batey, Robert T

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Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora von Blount, Kenneth F, Megyola, Cynthia, Plummer, Mark, Osterman, David, O'Connell, Tim, Aristoff, Paul, Quinn, Cheryl, Chrusciel, R Alan, Poel, Toni J, Schostarez, Heinrich J, Stewart, Catherine A, Walker, Daniel P, Wuts, Peter G M, Breaker, Ronald R

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Synthesis and biological evaluation of benzazepine oxazolidinone antibacterials von Johnson, Paul D., Aristoff, Paul A., Zurenko, Gary E., Schaadt, Ronda D., Yagi, Betty H., Ford, Charles W., Hamel, Judith C., Stapert, Douglas, Moerman, Judy K.

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Structure-activity relationship of flavin analogs that target the FMN riboswitch von Vicens, Quentin, Mondragón, Estefanía, Reyes, Francis E., Coish, Philip, Aristoff, Paul, Berman, Judd, Kaur, Harpreet, Kells, Kevin W., Wickens, Phil, Wilson, Jeffery, Gadwood, Robert C., Schostarez, Heinrich J., Suto, Robert K., Blount, Kenneth F., Batey, Robert T.

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Molecular basis for sequence-specific DNA alkylation by CC-1065 von Hurley, Laurence H, Lee, Chong Soon, McGovren, J. Patrick, Warpehoski, Martha A, Mitchell, Mark A, Kelly, Robert C, Aristoff, Paul A

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Tipranavir (PNU-140690):  A Potent, Orally Bioavailable Nonpeptidic HIV Protease Inhibitor of the 5,6-Dihydro-4-hydroxy-2-pyrone Sulfonamide Class von Turner, Steve R, Strohbach, Joseph W, Tommasi, Ruben A, Aristoff, Paul A, Johnson, Paul D, Skulnick, Harvey I, Dolak, Lester A, Seest, Eric P, Tomich, Paul K, Bohanon, Michael J, Horng, Miao-Miao, Lynn, Janet C, Chong, Kong-Teck, Hinshaw, Roger R, Watenpaugh, Keith D, Janakiraman, Musiri N, Thaisrivongs, Suvit

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Synthesis and biochemical evaluation of the CBI-PDE-I-dimer, a benzannelated analog of (+)-CC-1065 that also produces delayed toxicity in mice von Aristoff, Paul A, Johnson, Paul D, Sun, Daekyu, Hurley, Laurence H

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Thiadiazolidinones: A New Class of Alanine Racemase Inhibitors with Antimicrobial Activity against Methicillin- Resistant S. aureus von Ciustea, Mihai, Mootien, Sara, Rosato, Adriana E., Perez, Oriana, Cirillo, Pier, Yeung, Kacheong R., Ledizet, Michel, Cynamon, Michael H., Aristoff, Paul A., Koski, Raymond A., Kaplan, Paul A., Anthony, Karen G.

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Practical synthesis of 6a-carbaprostaglandin I2 von Aristoff, Paul A

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Coupling of cyclopropapyrroloindole (CPI) derivatives. The preparation of CC-1065, ent-CC-1065, and analogs von Kelly, Robert C, Gebhard, Ilse, Wicnienski, Nancy, Aristoff, Paul A, Johnson, Paul D, Martin, David G

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Reductive aromatization of quinols. New convenient methods for the regiospecific synthesis of p-hydroxy C-aryl glycals von Parker, Kathlyn A, Coburn, Craig A, Johnson, Paul D, Aristoff, Paul

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Interstrand DNA cross-linking with dimers of the spirocyclopropyl alkylating moiety of CC-1065 von Mitchell, Mark A, Johnson, Paul D, Williams, Marta G, Aristoff, Paul A

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