Pharmacological targeting of the unfolded protein response for disease intervention von Hetz, Claudio, Axten, Jeffrey M., Patterson, John B.

Volltext

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy von Logue, Susan E., McGrath, Eoghan P., Cleary, Patricia, Greene, Stephanie, Mnich, Katarzyna, Almanza, Aitor, Chevet, Eric, Dwyer, Róisín M., Oommen, Anup, Legembre, Patrick, Godey, Florence, Madden, Emma C., Leuzzi, Brian, Obacz, Joanna, Zeng, Qingping, Patterson, John B., Jäger, Richard, Gorman, Adrienne M., Samali, Afshin

Volltext

IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling von Sheng, Xia, Nenseth, Hatice Zeynep, Qu, Su, Kuzu, Omer F., Frahnow, Turid, Simon, Lukas, Greene, Stephanie, Zeng, Qingping, Fazli, Ladan, Rennie, Paul S., Mills, Ian G., Danielsen, Håvard, Theis, Fabian, Patterson, John B., Jin, Yang, Saatcioglu, Fahri

Volltext

Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer von Zhao, Na, Cao, Jin, Xu, Longyong, Tang, Qianzi, Dobrolecki, Lacey E, Lv, Xiangdong, Talukdar, Manisha, Lu, Yang, Wang, Xiaoran, Hu, Dorothy Z, Shi, Qing, Xiang, Yu, Wang, Yunfei, Liu, Xia, Bu, Wen, Jiang, Yi, Li, Mingzhou, Gong, Yingyun, Sun, Zheng, Ying, Haoqiang, Yuan, Bo, Lin, Xia, Feng, Xin-Hua, Hartig, Sean M, Li, Feng, Shen, Haifa, Chen, Yiwen, Han, Leng, Zeng, Qingping, Patterson, John B, Kaipparettu, Benny Abraham, Putluri, Nagireddy, Sicheri, Frank, Rosen, Jeffrey M, Lewis, Michael T, Chen, Xi

Volltext

Dual IRE1 RNase functions dictate glioblastoma development von Lhomond, Stéphanie, Avril, Tony, Dejeans, Nicolas, Voutetakis, Konstantinos, Doultsinos, Dimitrios, McMahon, Mari, Pineau, Raphaël, Obacz, Joanna, Papadodima, Olga, Jouan, Florence, Bourien, Heloise, Logotheti, Marianthi, Jégou, Gwénaële, Pallares‐Lupon, Néstor, Schmit, Kathleen, Le Reste, Pierre‐Jean, Etcheverry, Amandine, Mosser, Jean, Barroso, Kim, Vauléon, Elodie, Maurel, Marion, Samali, Afshin, Patterson, John B, Pluquet, Olivier, Hetz, Claudio, Quillien, Véronique, Chatziioannou, Aristotelis, Chevet, Eric

Volltext

Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells von Dastghaib, Sanaz, Shojaei, Shahla, Mostafavi-Pour, Zohreh, Sharma, Pawan, Patterson, John B, Samali, Afshin, Mokarram, Pooneh, Ghavami, Saeid

Volltext

Targeting IRE1α reprograms the tumor microenvironment and enhances anti-tumor immunity in prostate cancer von Unal, Bilal, Kuzu, Omer Faruk, Jin, Yang, Osorio, Daniel, Kildal, Wanja, Pradhan, Manohar, Kung, Sonia H. Y., Oo, Htoo Zarni, Daugaard, Mads, Vendelbo, Mikkel, Patterson, John B., Thomsen, Martin Kristian, Kuijjer, Marieke Lydia, Saatcioglu, Fahri

Volltext

Potent and Selective Inhibitors of the Inositol-requiring Enzyme 1 Endoribonuclease von Volkmann, Kori, Lucas, Julie L., Vuga, Danka, Wang, Xiaoping, Brumm, Duane, Stiles, Caryn, Kriebel, David, Der-Sarkissian, Ani, Krishnan, Kris, Schweitzer, Colleen, Liu, Zheng, Malyankar, Uriel M., Chiovitti, David, Canny, Marella, Durocher, Dan, Sicheri, Frank, Patterson, John B.

Volltext

Author Correction: IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling von Sheng, Xia, Nenseth, Hatice Zeynep, Qu, Su, Kuzu, Omer F., Frahnow, Turid, Simon, Lukas, Greene, Stephanie, Zeng, Qingping, Fazli, Ladan, Rennie, Paul S., Mills, Ian G., Danielsen, Håvard, Theis, Fabian, Patterson, John B., Jin, Yang, Saatcioglu, Fahri

Volltext

Modulation of intracellular calcium homeostasis blocks autophagosome formation von Engedal, Nikolai, Torgersen, Maria L, Guldvik, Ingrid J, Barfeld, Stefan J, Bakula, Daniela, Sætre, Frank, Hagen, Linda K, Patterson, John B, Proikas-Cezanne, Tassula, Seglen, Per O, Simonsen, Anne, Mills, Ian G

Volltext

Correction: Dastghaib et al. Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells. Cells 2020, 9 , 2339 von Dastghaib, Sanaz, Shojaei, Shahla, Mostafavi-Pour, Zohreh, Sharma, Pawan, Patterson, John B, Samali, Afshin, Mokarram, Pooneh, Ghavami, Saeid

Volltext

Dual IRE1 RNase functions dictate glioblastoma development von Lhomond, Stéphanie, Avril, Tony, Dejeans, Nicolas, Voutetakis, Konstantinos, Doultsinos, Dimitrios, McMahon, Mari, Pineau, Raphaël, Obacz, Joanna, Papadodima, Olga, Jouan, Florence, Bourien, Heloise, Logotheti, Marianthi, Jégou, Gwénaële, Pallares‐Lupon, Néstor, Schmit, Kathleen, Le Reste, Pierre‐Jean, Etcheverry, Amandine, Mosser, Jean, Barroso, Kim, Vauléon, Elodie, Maurel, Marion, Samali, Afshin, Patterson, John B, Pluquet, Olivier, Hetz, Claudio, Quillien, Véronique, Chatziioannou, Aristotelis, Chevet, Eric

Volltext

Stress Chaperone GRP78/BiP Confers Chemoresistance to Tumor-Associated Endothelial Cells von Virrey, Jenilyn J, Dong, Dezheng, Stiles, Caryn, Patterson, John B, Pen, Ligaya, Ni, Min, Schönthal, Axel H, Chen, Thomas C, Hofman, Florence M, Lee, Amy S

Volltext

Dual IRE1 RNase functions dictate glioblastoma development von Lhomond, Stéphanie, Avril, Tony, Dejeans, Nicolas, Voutetakis, Konstantinos, Doultsinos, Dimitrios, McMahon, Mari, Pineau, Raphaël, Obacz, Joanna, Papadodima, Olga, Jouan, Florence, Bourien, Heloise, Logotheti, Marianthi, Jégou, Gwénaële, Pallares‐Lupon, Néstor, Schmit, Kathleen, Le Reste, Pierre‐Jean, Etcheverry, Amandine, Mosser, Jean, Barroso, Kim, Vauléon, Elodie, Maurel, Marion, Samali, Afshin, Patterson, John B, Pluquet, Olivier, Hetz, Claudio, Quillien, Véronique, Chatziioannou, Aristotelis, Chevet, Eric

Volltext

Vascular targeting and antiangiogenesis agents induce drug resistance effector GRP78 within the tumor microenvironment von DEZHENG DONG, KO, Bryce, BAUMEISTER, Peter, SWENSON, Steven, COSTA, Fritz, MARKLAND, Frank, STILES, Caryn, PATTERSON, John B, BATES, Susan E, LEE, Amy S

Volltext

Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance von Rubio-Patiño, Camila, Bossowski, Jozef P., De Donatis, Gian Marco, Mondragón, Laura, Villa, Elodie, Aira, Lazaro E., Chiche, Johanna, Mhaidly, Rana, Lebeaupin, Cynthia, Marchetti, Sandrine, Voutetakis, Konstantinos, Chatziioannou, Aristotelis, Castelli, Florence A., Lamourette, Patricia, Chu-Van, Emeline, Fenaille, François, Avril, Tony, Passeron, Thierry, Patterson, John B., Verhoeyen, Els, Bailly-Maitre, Béatrice, Chevet, Eric, Ricci, Jean-Ehrland

Volltext

The IRE1 and PERK arms of the unfolded protein response promote survival of rhabdomyosarcoma cells von McCarthy, Nicole, Dolgikh, Nadezda, Logue, Susan, Patterson, John B., Zeng, Qinping, Gorman, Adrienne M., Samali, Afshin, Fulda, Simone

Volltext

Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma von Mimura, Naoya, Fulciniti, Mariateresa, Gorgun, Gullu, Tai, Yu-Tzu, Cirstea, Diana, Santo, Loredana, Hu, Yiguo, Fabre, Claire, Minami, Jiro, Ohguchi, Hiroto, Kiziltepe, Tanyel, Ikeda, Hiroshi, Kawano, Yutaka, French, Maureen, Blumenthal, Martina, Tam, Victor, Kertesz, Nathalie L., Malyankar, Uriel M., Hokenson, Mark, Pham, Tuan, Zeng, Qingping, Patterson, John B., Richardson, Paul G., Munshi, Nikhil C., Anderson, Kenneth C.

Volltext

Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo von Le Reste, Pierre Jean, Pineau, Raphael, Voutetakis, Konstantinos, Samal, Juhi, Jégou, Gwénaële, Lhomond, Stéphanie, Gorman, Adrienne M., Samali, Afshin, Patterson, John B., Zeng, Qingping, Pandit, Abhay, Aubry, Marc, Soriano, Nicolas, Etcheverry, Amandine, Chatziioannou, Aristotelis, Mosser, Jean, Avril, Tony, Chevet, Eric

Volltext

Publisher Correction: Pharmacological targeting of the unfolded protein response for disease intervention von Hetz, Claudio, Axten, Jeffrey M., Patterson, John B.

Volltext