Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells von Patsch, Christoph, Challet-Meylan, Ludivine, Thoma, Eva C., Urich, Eduard, Heckel, Tobias, O’Sullivan, John F., Grainger, Stephanie J., Kapp, Friedrich G., Sun, Lin, Christensen, Klaus, Xia, Yulei, Florido, Mary H. C., He, Wei, Pan, Wei, Prummer, Michael, Warren, Curtis R., Jakob-Roetne, Roland, Certa, Ulrich, Jagasia, Ravi, Freskgård, Per-Ola, Adatto, Isaac, Kling, Dorothee, Huang, Paul, Zon, Leonard I., Chaikof, Elliot L., Gerszten, Robert E., Graf, Martin, Iacone, Roberto, Cowan, Chad A.

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Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening von Gutbier, Simon, Wanke, Florian, Dahm, Nadine, Rümmelin, Anna, Zimmermann, Silke, Christensen, Klaus, Köchl, Fabian, Rautanen, Anna, Hatje, Klas, Geering, Barbara, Zhang, Jitao David, Britschgi, Markus, Cowley, Sally A, Patsch, Christoph

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Multicellular Self-Assembled Spheroidal Model of the Blood Brain Barrier von Urich, Eduard, Patsch, Christoph, Aigner, Stefan, Graf, Martin, Iacone, Roberto, Freskgård, Per-Ola

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Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance von Roudnicky, Filip, Kim, Bo Kyoung, Lan, Yanjun, Schmucki, Roland, Küppers, Verena, Christensen, Klaus, Graf, Martin, Patsch, Christoph, Burcin, Mark, Meyer, Claas Aiko, Westenskow, Peter D., Cowan, Chad A.

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Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells von Tünnemann, Gisela, Martin, Robert M, Haupt, Simone, Patsch, Christoph, Edenhofer, Frank, Cardoso, M. Cristina

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Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study von Volpato, Viola, Smith, James, Sandor, Cynthia, Ried, Janina S., Baud, Anna, Handel, Adam, Newey, Sarah E., Wessely, Frank, Attar, Moustafa, Whiteley, Emma, Chintawar, Satyan, Verheyen, An, Barta, Thomas, Lako, Majlinda, Armstrong, Lyle, Muschet, Caroline, Artati, Anna, Cusulin, Carlo, Christensen, Klaus, Patsch, Christoph, Sharma, Eshita, Nicod, Jerome, Brownjohn, Philip, Stubbs, Victoria, Heywood, Wendy E., Gissen, Paul, De Filippis, Roberta, Janssen, Katharina, Reinhardt, Peter, Adamski, Jerzy, Royaux, Ines, Peeters, Pieter J., Terstappen, Georg C., Graf, Martin, Livesey, Frederick J., Akerman, Colin J., Mills, Kevin, Bowden, Rory, Nicholson, George, Webber, Caleb, Cader, M. Zameel, Lakics, Viktor

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Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells von Roudnicky, Filip, Kim, Bo Kyoung, Pandya, Nikhil J., Lan, Yanjun, Sach-Peltason, Lisa, Ragelle, Heloise, Strassburger, Pamela, Gruener, Sabine, Lazendic, Mirjana, Uhles, Sabine, Revelant, Franco, Eidam, Oliv, Sturm, Gregor, Kueppers, Verena, Christensen, Klaus, Goldstein, Leonard D., Tzouros, Manuel, Banfai, Balazs, Modrusan, Zora, Graf, Martin, Patsch, Christoph, Burcin, Mark, Meyer, Claas A., Westenskow, Peter D., Cowan, Chad A.

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Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages von Wanke, Florian, Gutbier, Simon, Rümmelin, Anna, Steinberg, Malte, Hughes, Lindsey D., Koenen, Mascha, Komuczki, Juliana, Regan-Komito, Daniel, Wagage, Sagie, Hesselmann, Julia, Thoma, Ralf, Brugger, Doris, Christopeit, Tony, Wang, Hayian, Point, Floriane, Hallet, Remy, Ghosh, Sourav, Rothlin, Carla V., Patsch, Christoph, Geering, Barbara

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Sox2 is essential for formation of trophectoderm in the preimplantation embryo von Keramari, Maria, Razavi, Janet, Ingman, Karen A, Patsch, Christoph, Edenhofer, Frank, Ward, Christopher M, Kimber, Susan J

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Alzheimer's Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia von Reich, Marvin, Paris, Iñaki, Ebeling, Martin, Dahm, Nadine, Schweitzer, Christophe, Reinhardt, Dieter, Schmucki, Roland, Prasad, Megana, Köchl, Fabian, Leist, Marcel, Cowley, Sally A, Zhang, Jitao David, Patsch, Christoph, Gutbier, Simon, Britschgi, Markus

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mTORC1 Inhibition Corrects Neurodevelopmental and Synaptic Alterations in a Human Stem Cell Model of Tuberous Sclerosis von Costa, Veronica, Aigner, Stefan, Vukcevic, Mirko, Sauter, Evelyn, Behr, Katharina, Ebeling, Martin, Dunkley, Tom, Friedlein, Arno, Zoffmann, Sannah, Meyer, Claas A., Knoflach, Frédéric, Lugert, Sebastian, Patsch, Christoph, Fjeldskaar, Fatiha, Chicha-Gaudimier, Laurie, Kiialainen, Anna, Piraino, Paolo, Bedoucha, Marc, Graf, Martin, Jessberger, Sebastian, Ghosh, Anirvan, Bischofberger, Josef, Jagasia, Ravi

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Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice von Anastassiadis, Konstantinos, Fu, Jun, Patsch, Christoph, Hu, Shengbiao, Weidlich, Stefanie, Duerschke, Kristin, Buchholz, Frank, Edenhofer, Frank, Stewart, A Francis

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Ready-to-use iPSC-derived microglia progenitors for the treatment of CNS disease in mouse models of neuropathic mucopolysaccharidoses von Douvaras, Panagiotis, Buenaventura, Diego F., Sun, Bruce, Lepack, Ashley, Baker, Elizabeth, Simpson, Elizabeth, Ebel, Mark, Lallos, Gregory, LoSchiavo, Deven, Stitt, Nicholas, Adams, Nathaniel, McAuliffe, Conor, Forton-Juarez, Ana, Kosmyna, Brian, Pereira, Elizabeth, Burnett, Benjamin, Dilworth, David, Fisher, Stephanie, Wang, Jing, Tonge, Peter, Tomishima, Mark, Paladini, Carlos, Wilkinson, Dan, Soh, Chew-Li, Srinivas, Maya, Patsch, Christoph, Irion, Stefan

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Generation of functional podocytes from human induced pluripotent stem cells von Ciampi, Osele, Iacone, Roberto, Longaretti, Lorena, Benedetti, Valentina, Graf, Martin, Magnone, Maria Chiara, Patsch, Christoph, Xinaris, Christodoulos, Remuzzi, Giuseppe, Benigni, Ariela, Tomasoni, Susanna

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Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology von Pandya, Nikhil J., Wang, Congwei, Costa, Veronica, Lopatta, Paul, Meier, Sonja, Zampeta, F. Isabella, Punt, A. Mattijs, Mientjes, Edwin, Grossen, Philip, Distler, Tania, Tzouros, Manuel, Martí, Yasmina, Banfai, Balazs, Patsch, Christoph, Rasmussen, Soren, Hoener, Marius, Berrera, Marco, Kremer, Thomas, Dunkley, Tom, Ebeling, Martin, Distel, Ben, Elgersma, Ype, Jagasia, Ravi

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Generation of a homozygous GBA deletion human embryonic stem cell line von Gündner, Anna Lisa, Meyer, Claas Aiko, Aigner, Stefan, Christensen, Klaus, Patsch, Christoph, Jagasia, Ravi, Baumann, Karlheinz, Burcin, Mark

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Potent and Selective BACE-1 Peptide Inhibitors Lower Brain Aβ Levels Mediated by Brain Shuttle Transport von Ruderisch, Nadine, Schlatter, Daniel, Kuglstatter, Andreas, Guba, Wolfgang, Huber, Sylwia, Cusulin, Carlo, Benz, Jörg, Rufer, Arne Christian, Hoernschemeyer, Joerg, Schweitzer, Christophe, Bülau, Tina, Gärtner, Achim, Hoffmann, Eike, Niewoehner, Jens, Patsch, Christoph, Baumann, Karlheinz, Loetscher, Hansruedi, Kitas, Eric, Freskgård, Per-Ola

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Engineering Cell‐Permeant FLP Recombinase for Tightly Controlled Inducible and Reversible Overexpression in Embryonic Stem Cells von Patsch, Christoph, Peitz, Michael, Otte, David M., Kesseler, Daniela, Jungverdorben, Johannes, Wunderlich, Frank Thomas, Brüstle, Oliver, Zimmer, Andreas, Edenhofer, Frank

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Monolayer Generation of Vascular Endothelial Cells from Human Pluripotent Stem Cells von Christensen, Klaus, Roudnicky, Filip, Burcin, Mark, Patsch, Christoph

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Gamma secretase modulators and BACE inhibitors reduce Aβ production without altering gene expression in Alzheimer's disease iPSC-derived neurons and mice von Cusulin, Carlo, Wells, Isabelle, Badillo, Solveig, Duran-Pacheco, Gonzalo Christian, Baumann, Karlheinz, Patsch, Christoph

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