N-Heterocyclic Carbene-Amine Pt(II) Complexes, a New Chemical Space for the Development of Platinum-Based Anticancer Drugs von Skander, Myriem, Retailleau, Pascal, Bourrié, Bernard, Schio, Laurent, Mailliet, Patrick, Marinetti, Angela

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Variations in the colchicine-binding domain provide insight into the structural switch of tubulin von Dorléans, Audrey, Gigant, Benoît, Ravelli, Raimond B.G, Mailliet, Patrick, Mikol, Vincent, Knossow, Marcel

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Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands von Pennarun, Gaëlle, Granotier, Christine, Gauthier, Laurent R, Gomez, Dennis, Hoffschir, Françoise, Mandine, Eliane, Riou, Jean-François, Mergny, Jean-Louis, Mailliet, Patrick, Boussin, François D

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Investigating the Effect of Mono- and Dimeric 360A G-Quadruplex Ligands on Telomere Stability by Single Telomere Length Analysis (STELA) von Hwang, In Pyo, Mailliet, Patrick, Hossard, Virginie, Riou, Jean-Francois, Bugaut, Anthony, Roger, Lauréline

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Stabilization of the c-myc gene promoter quadruplex by specific ligands’ inhibitors of telomerase von Lemarteleur, Thibault, Gomez, Dennis, Paterski, Rajaa, Mandine, Eliane, Mailliet, Patrick, Riou, Jean-François

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Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-c]pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone von Vallée, François, Carrez, Chantal, Pilorge, Fabienne, Dupuy, Alain, Parent, Annick, Bertin, Luc, Thompson, Fabienne, Ferrari, Paul, Fassy, Florence, Lamberton, Annabelle, Thomas, Anne, Arrebola, Rosalia, Guerif, Stéphane, Rohaut, Alexandre, Certal, Victor, Ruxer, Jean-Marie, Delorme, Cécile, Jouanen, Alain, Dumas, Jacques, Grépin, Claudine, Combeau, Cécile, Goulaouic, Hélène, Dereu, Norbert, Mikol, Vincent, Mailliet, Patrick, Minoux, Hervé

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Resistance to the Short Term Antiproliferative Activity of the G-quadruplex Ligand 12459 Is Associated with Telomerase Overexpression and Telomere Capping Alteration von Gomez, Dennis, Aouali, Nassera, Londoño-Vallejo, Arturo, Lacroix, Laurent, Mégnin-Chanet, Frédérique, Lemarteleur, Thibault, Douarre, Céline, Shin-ya, Kazuo, Mailliet, Patrick, Trentesaux, Chantal, Morjani, Hamid, Mergny, Jean-Louis, Riou, Jean-François

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Telomerase: a therapeutic target for the third millennium? von Lavelle, François, Riou, Jean-François, Laoui, Abdelazize, Mailliet, Patrick

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Cooperative 2:1 Binding of a Bisphenothiazine to Duplex DNA von Rosu, Frédéric, Gabelica, Valérie, De Pauw, Edwin, Mailliet, Patrick, Mergny, Jean-Louis

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Natural and pharmacological regulation of telomerase von Mergny, Jean-Louis, Riou, Jean-François, Mailliet, Patrick, Teulade-Fichou, Marie-Paule, Gilson, Eric

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Ring-Closing Enyne Metathesis of Terminal Alkynes with Propargylic Hindrance von Laroche, Benjamin, Detraz, Morgane, Blond, Alain, Dubost, Lionel, Mailliet, Patrick, Nay, Bastien

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DNA damage signaling induced by the G-quadruplex ligand 12459 is modulated by PPM1D/WIP1 phosphatase von Douarre, Céline, Mergui, Xénia, Sidibe, Assitan, Gomez, Dennis, Alberti, Patrizia, Mailliet, Patrick, Trentesaux, Chantal, Riou, Jean-François

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Telomerase downregulation induced by the G‐quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing von Gomez, Dennis, Lemarteleur, Thibault, Lacroix, Laurent, Mailliet, Patrick, Mergny, Jean‐Louis, Riou, Jean‐François

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Preferential binding of a G-quadruplex ligand to human chromosome ends von Granotier, Christine, Pennarun, Gaëlle, Riou, Lydia, Hoffschir, Françoise, Gauthier, Laurent R., De Cian, Anne, Gomez, Dennis, Mandine, Eliane, Riou, Jean-François, Mergny, Jean-Louis, Mailliet, Patrick, Dutrillaux, Bernard, Boussin, François D.

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Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death von Gauthier, Laurent R., Granotier, Christine, Hoffschir, Françoise, Etienne, Olivier, Ayouaz, Ali, Desmaze, Chantal, Mailliet, Patrick, Biard, Denis S., Boussin, François D.

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Total Synthesis of Herbimycin A von Canova, Sophie, Bellosta, Véronique, Bigot, Antony, Mailliet, Patrick, Mignani, Serge, Cossy, Janine

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A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT) von Jeitany, Maya, Pineda, Jose Ramon, Liu, Qingyuan, Porreca, Rosa Maria, Hoffschir, Françoise, Desmaze, Chantal, Silvestre, David C., Mailliet, Patrick, Junier, Marie‐Pierre, Londoño‐Vallejo, Arturo, Ségal‐Bendirdjian, Evelyne, Chneiweiss, Hervé, Boussin, François D.

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Targeting human telomerase for cancer therapeutics von Guittat, Lionel, Alberti, Patrizia, Gomez, Dennis, De Cian, Anne, Pennarun, Gaëlle, Lemarteleur, Thibault, Belmokhtar, Chafke, Paterski, Rajaa, Morjani, Hamid, Trentesaux, Chantal, Mandine, Eliane, Boussin, François, Mailliet, Patrick, Lacroix, Laurent, Riou, Jean-François, Mergny, Jean-Louis

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ATR contributes to telomere maintenance in human cells von Pennarun, Gaëlle, Hoffschir, Françoise, Revaud, Deborah, Granotier, Christine, Gauthier, Laurent R, Mailliet, Patrick, Biard, Denis S, Boussin, François D

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Selective Interaction of Ethidium Derivatives with Quadruplexes:  An Equilibrium Dialysis and Electrospray Ionization Mass Spectrometry Analysis von Rosu, Frederic, De Pauw, Edwin, Guittat, Lionel, Alberti, Patrizia, Lacroix, Laurent, Mailliet, Patrick, Riou, Jean-François, Mergny, Jean-Louis

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