Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation von Glassman, Caleb R, Tsutsumi, Naotaka, Saxton, Robert A, Lupardus, Patrick J, Jude, Kevin M, Garcia, K Christopher

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The Janus Kinase (JAK) FERM and SH2 Domains: Bringing Specificity to JAK-Receptor Interactions von Ferrao, Ryan, Lupardus, Patrick J

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Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition von Lupardus, Patrick J., Ultsch, Mark, Wallweber, Heidi, Kohli, Pawan Bir, Johnson, Adam R., Eigenbrot, Charles

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The Structural Basis for Class II Cytokine Receptor Recognition by JAK1 von Ferrao, Ryan, Wallweber, Heidi J.A., Ho, Hoangdung, Tam, Christine, Franke, Yvonne, Quinn, John, Lupardus, Patrick J.

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Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function von Hackos, David H., Lupardus, Patrick J., Grand, Teddy, Chen, Yelin, Wang, Tzu-Ming, Reynen, Paul, Gustafson, Amy, Wallweber, Heidi J.A., Volgraf, Matthew, Sellers, Benjamin D., Schwarz, Jacob B., Paoletti, Pierre, Sheng, Morgan, Zhou, Qiang, Hanson, Jesse E.

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Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells von Glassman, Caleb R., Mathiharan, Yamuna Kalyani, Jude, Kevin M., Su, Leon, Panova, Ouliana, Lupardus, Patrick J., Spangler, Jamie B., Ely, Lauren K., Thomas, Christoph, Skiniotis, Georgios, Garcia, K. Christopher

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Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability von Lauffer, Benjamin E.L., Mintzer, Robert, Fong, Rina, Mukund, Susmith, Tam, Christine, Zilberleyb, Inna, Flicke, Birgit, Ritscher, Allegra, Fedorowicz, Grazyna, Vallero, Roxanne, Ortwine, Daniel F., Gunzner, Janet, Modrusan, Zora, Neumann, Lars, Koth, Christopher M., Lupardus, Patrick J., Kaminker, Joshua S., Heise, Christopher E., Steiner, Pascal

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Structural biology of shared cytokine receptors von Wang, Xinquan, Lupardus, Patrick, Laporte, Sherry L, Garcia, K Christopher

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Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation von Ferrao, Ryan D, Wallweber, Heidi Ja, Lupardus, Patrick J

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Structural basis of recognition of interferon-α receptor by tyrosine kinase 2 von Wallweber, Heidi J A, Tam, Christine, Franke, Yvonne, Starovasnik, Melissa A, Lupardus, Patrick J

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Structural Organization of a Full-Length gp130/LIF-R Cytokine Receptor Transmembrane Complex von Skiniotis, Georgios, Lupardus, Patrick J., Martick, Monika, Walz, Thomas, Garcia, K. Christopher

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Simplified, enhanced protein purification using an inducible, autoprocessing enzyme tag von Shen, Aimee, Lupardus, Patrick J, Morell, Montse, Ponder, Elizabeth L, Sadaghiani, A Masoud, Garcia, K Christopher, Bogyo, Matthew

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Mutation position is an important determinant for predicting cancer neoantigens von Capietto, Aude-Helene, Jhunjhunwala, Suchit, Pollock, Samuel B., Lupardus, Patrick, Wong, Jim, Hansch, Lena, Cevallos, James, Chestnut, Yajun, Fernandez, Ajay, Lounsbury, Nicolas, Nozawa, Tamaki, Singh, Manmeet, Fan, Zhiyuan, de la Cruz, Cecile C., Phung, Qui T., Taraborrelli, Lucia, Haley, Benjamin, Lill, Jennie R., Mellman, Ira, Bourgon, Richard, Delamarre, Lelia

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The Structure of Interleukin-23 Reveals the Molecular Basis of p40 Subunit Sharing with Interleukin-12 von Lupardus, Patrick J., Garcia, K. Christopher

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Molecular Basis for Shared Cytokine Recognition Revealed in the Structure of an Unusually High Affinity Complex between IL-13 and IL-13R alpha 2 von Lupardus, Patrick J, Birnbaum, Michael E, Garcia, KChristopher

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Small Molecule-Induced Allosteric Activation of the Vibrio cholerae RTX Cysteine Protease Domain von Lupardus, Patrick J, Shen, Aimee, Bogyo, Matthew, Garcia, K. Christopher

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Structural investigation of human S. aureus-targeting antibodies that bind wall teichoic acid von Fong, Rina, Kajihara, Kimberly, Chen, Matthew, Hotzel, Isidro, Mariathasan, Sanjeev, Hazenbos, Wouter L W, Lupardus, Patrick J

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Two Escape Mechanisms of Influenza A Virus to a Broadly Neutralizing Stalk-Binding Antibody von Chai, Ning, Swem, Lee R, Reichelt, Mike, Chen-Harris, Haiyin, Luis, Elizabeth, Park, Summer, Fouts, Ashley, Lupardus, Patrick, Wu, Thomas D, Li, Olga, McBride, Jacqueline, Lawrence, Michael, Xu, Min, Tan, Man-Wah

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An In Vivo Human-Plasmablast Enrichment Technique Allows Rapid Identification of Therapeutic Influenza A Antibodies von Nakamura, Gerald, Chai, Ning, Park, Summer, Chiang, Nancy, Lin, Zhonghua, Chiu, Henry, Fong, Rina, Yan, Donghong, Kim, Janice, Zhang, Juan, Lee, Wyne P., Estevez, Alberto, Coons, Mary, Xu, Min, Lupardus, Patrick, Balazs, Mercedesz, Swem, Lee R.

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Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group von Hamilton, Gregory L., Chen, Huifen, Deshmukh, Gauri, Eigenbrot, Charles, Fong, Rina, Johnson, Adam, Kohli, Pawan Bir, Lupardus, Patrick J., Liederer, Bianca M., Ramaswamy, Sreemathy, Wang, Haowei, Wang, Jian, Xu, Zhaowu, Zhu, Yunliang, Vucic, Domagoj, Patel, Snahel

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