DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome von Samir, Parimal, Kesavardhana, Sannula, Patmore, Deanna M., Gingras, Sebastien, Malireddi, R. K. Subbarao, Karki, Rajendra, Guy, Clifford S., Briard, Benoit, Place, David E., Bhattacharya, Anannya, Sharma, Bhesh Raj, Nourse, Amanda, King, Sharon V., Pitre, Aaron, Burton, Amanda R., Pelletier, Stephane, Gilbertson, Richard J., Kanneganti, Thirumala-Devi

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Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation von Valentin-Vega, Yasmine A., Wang, Yong-Dong, Parker, Matthew, Patmore, Deanna M., Kanagaraj, Anderson, Moore, Jennifer, Rusch, Michael, Finkelstein, David, Ellison, David W., Gilbertson, Richard J., Zhang, Jinghui, Kim, Hong Joo, Taylor, J. Paul

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Author Correction: Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation von Valentin-Vega, Yasmine A., Wang, Yong-Dong, Parker, Matthew, Patmore, Deanna M., Kanagaraj, Anderson, Moore, Jennifer, Rusch, Michael, Finkelstein, David, Ellison, David W., Gilbertson, Richard J., Zhang, Jinghui, Kim, Hong Joo, Taylor, J. Paul

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Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation von Wu, Jianqiang, Keng, Vincent W., Patmore, Deanna M., Kendall, Jed J., Patel, Ami V., Jousma, Edwin, Jessen, Walter J., Choi, Kwangmin, Tschida, Barbara R., Silverstein, Kevin A.T., Fan, Danhua, Schwartz, Eric B., Fuchs, James R., Zou, Yuanshu, Kim, Mi-Ok, Dombi, Eva, Levy, David E., Huang, Gang, Cancelas, Jose A., Stemmer-Rachamimov, Anat O., Spinner, Robert J., Largaespada, David A., Ratner, Nancy

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Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype von Phoenix, Timothy N., Patmore, Deanna M., Boop, Scott, Boulos, Nidal, Jacus, Megan O., Patel, Yogesh T., Roussel, Martine F., Finkelstein, David, Goumnerova, Liliana, Perreault, Sebastien, Wadhwa, Elizabeth, Cho, Yoon-Jae, Stewart, Clinton F., Gilbertson, Richard J.

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DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma von Patmore, Deanna M., Jassim, Amir, Nathan, Erica, Gilbertson, Reuben J., Tahan, Daniel, Hoffmann, Nadin, Tong, Yiai, Smith, Kyle S., Kanneganti, Thirumala-Devi, Suzuki, Hiromichi, Taylor, Michael D., Northcott, Paul, Gilbertson, Richard J.

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In Vivo Regulation of TGF-β by R-Ras2 Revealed through Loss of the RasGAP Protein NF1 von PATMORE, Deanna M, WELCH, Sara, FULKERSON, Patricia C, JIANQIANG WU, CHOI, Kwangmin, EAVES, David, KORDICH, Jennifer J, COLLINS, Margaret H, CRIPE, Timothy P, RATNER, Nancy

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EGFR–STAT3 signaling promotes formation of malignant peripheral nerve sheath tumors von Wu, J, Patmore, D M, Jousma, E, Eaves, D W, Breving, K, Patel, A V, Schwartz, E B, Fuchs, J R, Cripe, T P, Stemmer-Rachamimov, A O, Ratner, N

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Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis von Miller, S J, Lan, Z D, Hardiman, A, Wu, J, Kordich, J J, Patmore, D M, Hegde, R S, Cripe, T P, Cancelas, J A, Collins, M H, Ratner, N

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Abstract 1433: TC21/R-Ras2 is a critical mediator of the Nf1 oncogenic switch von Patmore, Deanna M., Welch, Sara, Fulkerson, Patricia, Wu, Jianqiang, Choi, Kwangmin, Eaves, David, Kordich, Jennifer, Collins, Margaret H., Cripe, Timothy P., Ratner, Nancy

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PM-18EGFR-STAT3 ACTIVATES β-CATENIN SIGNALING TO DRIVE NEUROFIBROMA INITIATION IN NF1, AND PLAYS A ROLE IN TUMOR MAINTENANCE von Ratner, Nancy, Keng, Vincent, Patmore, Deanna M., Kendall, Jed K., Jousma, Edwin, Choi, Kwangmin, Fan, Danhua, Schwartz, Eric B., Fuchs, James R., Zou, Yuanshu, Kim, Mi-Ok, Dombi, Eva, Levy, David E., Cancelas, Jose A., Stemmer-Rachamimov, Anat, Spinner, Robert J., Largaespada, David A.

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PM-18 EGFR-STAT3 ACTIVATES beta -CATENIN SIGNALING TO DRIVE NEUROFIBROMA INITIATION IN NF1, AND PLAYS A ROLE IN TUMOR MAINTENANCE von Ratner, Nancy, Keng, Vincent, Patmore, Deanna M, Kendall, Jed K, Jousma, Edwin, Choi, Kwangmin, Fan, Danhua, Schwartz, Eric B, Fuchs, James R, Zou, Yuanshu, Kim, Mi-Ok, Dombi, Eva, Levy, David E, Cancelas, Jose A, Stemmer-Rachamimov, Anat, Spinner, Robert J, Largaespada, David A

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Abstract 2937: An EGFR-STAT3 pathway promotes NF1 peripheral nerve tumorigenesis and transformation von Wu, Jianqiang, Keng, Vincent, Patmore, Deanna M., Jousma, Edwin, Eaves, David W., Johansson, Gunnar, Schwartz, Eric B., Fuchs, James R., Dunn, Scott, Lindquist, Diana, Dombi, Eva, Widemann, Brigitte C., Stemmer-Rachamimov, Anat o., Cancelas, Jose A., Cripe, Timothy P., Largaespada, David A., Ratner, Nancy

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DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome von Samir, Parimal, Kesavardhana, Sannula, Patmore, Deanna M, Gingras, Sebastien, Malireddi, RK Subbarao, Karki, Rajendra, Guy, Clifford S, Briard, Benoit, Place, David E, Bhattacharya, Anannya, Sharma, Bhesh Raj, Nourse, Amanda, King, Sharon V, Pitre, Aaron, Burton, Amanda R, Pelletier, Stephane, Gilbertson, Richard J, Kanneganti, Thirumala-Devi

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Medulloblastoma genotype dictates blood brain barrier phenotype von Phoenix, Timothy N, Patmore, Deanna M, Boop, Scott, Boulos, Nidal, Jacus, Megan O, Patel, Yogesh T, Roussel, Martine F, Finkelstein, David, Goumnerova, Liliana, Perreault, Sebastien, Wadhwa, Elizabeth, Cho, Yoon-Jae, Stewart, Clinton F, Gilbertson, Richard James

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