An environment-dependent transcriptional network specifies human microglia identity von Gosselin, David, Skola, Dylan, Coufal, Nicole G., Holtman, Inge R., Schlachetzki, Johannes C. M., Sajti, Eniko, Jaeger, Baptiste N., O’Connor, Carolyn, Fitzpatrick, Conor, Pasillas, Martina P., Pena, Monique, Adair, Amy, Gonda, David D., Levy, Michael L., Ransohoff, Richard M., Gage, Fred H., Glass, Christopher K.

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Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis von Seidman, Jason S., Troutman, Ty D., Sakai, Mashito, Gola, Anita, Spann, Nathanael J., Bennett, Hunter, Bruni, Cassi M., Ouyang, Zhengyu, Li, Rick Z., Sun, Xiaoli, Vu, BaoChau T., Pasillas, Martina P., Ego, Kaori M., Gosselin, David, Link, Verena M., Chong, Ling-Wa, Evans, Ronald M., Thompson, Bonne M., McDonald, Jeffrey G., Hosseini, Mojgan, Witztum, Joseph L., Germain, Ronald N., Glass, Christopher K.

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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4 von Gratuze, Maud, Schlachetzki, Johannes C.M., D’Oliveira Albanus, Ricardo, Jain, Nimansha, Novotny, Brenna, Brase, Logan, Rodriguez, Lea, Mansel, Clayton, Kipnis, Michal, O’Brien, Sydney, Pasillas, Martina P., Lee, Choonghee, Manis, Melissa, Colonna, Marco, Harari, Oscar, Glass, Christopher K., Ulrich, Jason D., Holtzman, David M.

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Heterogeneity of HSCs in a Mouse Model of NASH von Rosenthal, Sara Brin, Liu, Xiao, Ganguly, Souradipta, Dhar, Debanjan, Pasillas, Martina P., Ricciardelli, Eugenia, Li, Rick Z., Troutman, Ty D., Kisseleva, Tatiana, Glass, Christopher K., Brenner, David A.

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Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity von Sakai, Mashito, Troutman, Ty D., Seidman, Jason S., Ouyang, Zhengyu, Spann, Nathanael J., Abe, Yohei, Ego, Kaori M., Bruni, Cassi M., Deng, Zihou, Schlachetzki, Johannes C.M., Nott, Alexi, Bennett, Hunter, Chang, Jonathan, Vu, BaoChau T., Pasillas, Martina P., Link, Verena M., Texari, Lorane, Heinz, Sven, Thompson, Bonne M., McDonald, Jeffrey G., Geissmann, Frederic, Glass, Christopher K.

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NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis von Wang, Gang G, Kamps, Mark P, Cai, Ling, Pasillas, Martina P

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Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis von Sun, Xiaoli, Seidman, Jason S., Zhao, Peng, Troutman, Ty D., Spann, Nathanael J., Que, Xuchu, Zhou, Fangli, Liao, Zhongji, Pasillas, Martina, Yang, Xiaohong, Magida, Jason A., Kisseleva, Tatiana, Brenner, David A., Downes, Michael, Evans, Ronald M., Saltiel, Alan R., Tsimikas, Sotirios, Glass, Christopher K., Witztum, Joseph L.

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Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8 von Kamps, Mark P, Wang, Gang G, Calvo, Katherine R, Pasillas, Martina P, Sykes, David B, Häcker, Hans

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Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes von Bennett, Hunter, Troutman, Ty D., Zhou, Enchen, Spann, Nathanael J., Link, Verena M., Seidman, Jason S., Nickl, Christian K., Abe, Yohei, Sakai, Mashito, Pasillas, Martina P., Marlman, Justin M., Guzman, Carlos, Hosseini, Mojgan, Schnabl, Bernd, Glass, Christopher K.

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Brain cell type-specific enhancer-promoter interactome maps and disease - risk association von Nott, Alexi, Holtman, Inge R, Coufal, Nicole G, Schlachetzki, Johannes C M, Yu, Miao, Hu, Rong, Han, Claudia Z, Pena, Monique, Xiao, Jiayang, Wu, Yin, Keulen, Zahara, Pasillas, Martina P, O'Connor, Carolyn, Nickl, Christian K, Schafer, Simon T, Shen, Zeyang, Rissman, Robert A, Brewer, James B, Gosselin, David, Gonda, David D, Levy, Michael L, Rosenfeld, Michael G, McVicker, Graham, Gage, Fred H, Ren, Bing, Glass, Christopher K

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SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity von Fixsen, Bethany R., Han, Claudia Z., Zhou, Yi, Spann, Nathanael J., Saisan, Payam, Shen, Zeyang, Balak, Christopher, Sakai, Mashito, Cobo, Isidoro, Holtman, Inge R., Warden, Anna S., Ramirez, Gabriela, Collier, Jana G., Pasillas, Martina P., Yu, Miao, Hu, Rong, Li, Bin, Belhocine, Sarah, Gosselin, David, Coufal, Nicole G., Ren, Bing, Glass, Christopher K.

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Human microglia maturation is underpinned by specific gene regulatory networks von Han, Claudia Z., Li, Rick Z., Hansen, Emily, Trescott, Samantha, Fixsen, Bethany R., Nguyen, Celina T., Mora, Cristina M., Spann, Nathanael J., Bennett, Hunter R., Poirion, Olivier, Buchanan, Justin, Warden, Anna S., Xia, Bing, Schlachetzki, Johannes C.M., Pasillas, Martina P., Preissl, Sebastian, Wang, Allen, O’Connor, Carolyn, Shriram, Shreya, Kim, Roy, Schafer, Danielle, Ramirez, Gabriela, Challacombe, Jean, Anavim, Samuel A., Johnson, Avalon, Gupta, Mihir, Glass, Ian A., Levy, Michael L., Haim, Sharona Ben, Gonda, David D., Laurent, Louise, Hughes, Jennifer F., Page, David C., Blurton-Jones, Mathew, Glass, Christopher K., Coufal, Nicole G.

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Proteomic Analysis Reveals a Role for Bcl2-associated Athanogene 3 and Major Vault Protein in Resistance to Apoptosis in Senescent Cells by Regulating ERK1/2 Activation von Pasillas, Martina P., Shields, Sarah, Reilly, Rebecca, Strnadel, Jan, Behl, Christian, Park, Robin, Yates, John R., Klemke, Richard, Gonias, Steven L., Coppinger, Judith A.

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NSD1 PHD domains bind methylated H3K4 and H3K9 using interactions disrupted by point mutations in human sotos syndrome von Pasillas, Martina P, Shah, Meera, Kamps, Mark P

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Persistent Transactivation by Meis1 Replaces Hox Function in Myeloid Leukemogenesis Models: Evidence for Co-Occupancy of Meis1-Pbx and Hox-Pbx Complexes on Promoters of Leukemia-As... von Wang, Gang G., Pasillas, Martina P., Kamps, Mark P.

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Somatic mosaicism reveals clonal distributions of neocortical development von Breuss, Martin W., Yang, Xiaoxu, Schlachetzki, Johannes C. M., Antaki, Danny, Lana, Addison J., Xu, Xin, Chung, Changuk, Chai, Guoliang, Stanley, Valentina, Song, Qiong, Newmeyer, Traci F., Nguyen, An, O’Brien, Sydney, Hoeksema, Marten A., Cao, Beibei, Nott, Alexi, McEvoy-Venneri, Jennifer, Pasillas, Martina P., Barton, Scott T., Copeland, Brett R., Nahas, Shareef, Van Der Kraan, Lucitia, Ding, Yan, Glass, Christopher K., Gleeson, Joseph G.

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Novel Genes Critical for Hypoxic Preconditioning in Zebrafish Are Regulators of Insulin and Glucose Metabolism von Manchenkov, Tania, Pasillas, Martina P, Haddad, Gabriel G, Imam, Farhad B

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Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus von Wang, Gang G., Pasillas, Martina P., Kamps, Mark P.

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Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retrovira... von CALVO, Katherine R, SYKES, David B, PASILLAS, Martina P, KAMPS, Mark P

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Meis1a Suppresses Differentiation by G-CSF and Promotes Proliferation by SCF: Potential Mechanisms of Cooperativity with Hoxa9 in Myeloid Leukemia von Calvo, Katherine R., Knoepfler, Paul S., Sykes, David B., Pasillas, Martina P., Kamps, Mark P.

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