Kinase drug discovery 20 years after imatinib: progress and future directions von Cohen, Philip, Cross, Darren, Jänne, Pasi A.

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Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M von Thress, Kenneth S, Paweletz, Cloud P, Felip, Enriqueta, Cho, Byoung Chul, Stetson, Daniel, Dougherty, Brian, Lai, Zhongwu, Markovets, Aleksandra, Vivancos, Ana, Kuang, Yanan, Ercan, Dalia, Matthews, Sarah E, Cantarini, Mireille, Barrett, J Carl, Jänne, Pasi A, Oxnard, Geoffrey R

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The quest to overcome resistance to EGFR-targeted therapies in cancer von Chong, Curtis R, Jänne, Pasi A

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Kinase drug discovery 20 years after imatinib von Cohen, Philip, Cross, Darren, Jänne, Pasi A

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Mechanisms of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small Cell Lung Cancer von Engelman, Jeffrey A., Jänne, Pasi A.

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New Targetable Oncogenes in Non–Small-Cell Lung Cancer von Oxnard, Geoffrey R, Binder, Adam, Jaenne, Pasi A

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MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling von Engelman, Jeffrey A, Zejnullahu, Kreshnik, Mitsudomi, Tetsuya, Song, Youngchul, Hyland, Courtney, Park, Joon Oh, Lindeman, Neal, Gale, Christopher-Michael, Zhao, Xiaojun, Christensen, James, Kosaka, Takayuki, Holmes, Alison J, Rogers, Andrew M, Cappuzzo, Federico, Mok, Tony, Lee, Charles, Johnson, Bruce E, Cantley, Lewis C, Jänne, Pasi A

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EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors von Ercan, Dalia, Choi, Hwan Geun, Yun, Cai-Hong, Capelletti, Marzia, Xie, Ting, Eck, Michael J, Gray, Nathanael S, Jänne, Pasi A

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False positive plasma genotyping due to clonal hematopoiesis von Hu, Yuebi, Ulrich, Bryan, Supplee, Julianna, Kuang, Yanan, Lizotte, Patrick H, Feeney, Nora, Guibert, Nicolas, Awad, Mark M, Wong, Kwok-Kin, Janne, Pasi A, Paweletz, Cloud Peter, Oxnard, Geoffrey R

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Overcoming therapy resistance in EGFR-mutant lung cancer von Passaro, Antonio, Jänne, Pasi A, Mok, Tony, Peters, Solange

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Thirty Years of HER3: From Basic Biology to Therapeutic Interventions von Haikala, Heidi M, Jänne, Pasi A

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The biology and treatment of EML4-ALK non-small cell lung cancer von Sasaki, Takaaki, Rodig, Scott J, Chirieac, Lucian R, Jänne, Pasi A

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Antibody-Drug Conjugates in Lung Cancer: Recent Advances and Implementing Strategies von Passaro, Antonio, Jänne, Pasi A, Peters, Solange

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Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor von Lim, Sang Min, Westover, Kenneth D., Ficarro, Scott B., Harrison, Rane A., Choi, Hwan Geun, Pacold, Michael E., Carrasco, Martin, Hunter, John, Kim, Nam Doo, Xie, Ting, Sim, Taebo, Jänne, Pasi A., Meyerson, Matthew, Marto, Jarrod A., Engen, John R., Gray, Nathanael S.

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Targeting MET Dysregulation in Cancer von Recondo, Gonzalo, Che, Jianwei, Jänne, Pasi A, Awad, Mark M

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Selumetinib plus docetaxel for KRAS -mutant advanced non-small-cell lung cancer: a randomised, multicentre, placebo-controlled, phase 2 study von Jänne, Pasi A, Dr, Shaw, Alice T, MD, Pereira, José Rodrigues, MD, Jeannin, Gaëlle, MD, Vansteenkiste, Johan, Prof, Barrios, Carlos, MD, Franke, Fabio Andre, MD, Grinsted, Lynda, MSc, Zazulina, Victoria, MD, Smith, Paul, PhD, Smith, Ian, MD, Crinò, Lucio, Prof

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Drug-Induced Death Signaling Strategy Rapidly Predicts Cancer Response to Chemotherapy von Montero, Joan, Sarosiek, Kristopher A., DeAngelo, Joseph D., Maertens, Ophélia, Ryan, Jeremy, Ercan, Dalia, Piao, Huiying, Horowitz, Neil S., Berkowitz, Ross S., Matulonis, Ursula, Jänne, Pasi A., Amrein, Philip C., Cichowski, Karen, Drapkin, Ronny, Letai, Anthony

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Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK) von Powell, Chelsea E, Gao, Yang, Tan, Li, Donovan, Katherine A, Nowak, Radosław P, Loehr, Amanda, Bahcall, Magda, Fischer, Eric S, Jänne, Pasi A, George, Rani E, Gray, Nathanael S

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Osimertinib As First-Line Treatment of EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer von Ramalingam, Suresh S, Yang, James C-H, Lee, Chee Khoon, Kurata, Takayasu, Kim, Dong-Wan, John, Thomas, Nogami, Naoyuki, Ohe, Yuichiro, Mann, Helen, Rukazenkov, Yuri, Ghiorghiu, Serban, Stetson, Daniel, Markovets, Aleksandra, Barrett, J Carl, Thress, Kenneth S, Jänne, Pasi A

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Basket trials and the evolution of clinical trial design in an era of genomic medicine von Redig, Amanda J, Jänne, Pasi A

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