Zika antiviral chemotherapy: identification of drugs and promising starting points for drug discovery from an FDA-approved library [version 1; peer review: 2 approved] von Pascoalino, Bruno S, Courtemanche, Gilles, Cordeiro, Marli T, Gil, Laura H. V. G, Freitas-Junior, Lucio H

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Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity von Franco, Caio H., Warhurst, David C., Bhattacharyya, Tapan, Au, Ho Y.A., Le, Hai, Giardini, Miriam A., Pascoalino, Bruno S., Torrecilhas, Ana Claudia, Romera, Lavinia M.D., Madeira, Rafael Pedro, Schenkman, Sergio, Freitas-Junior, Lucio H., Chatelain, Eric, Miles, Michael A., Moraes, Carolina B.

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In Vitro and In Vivo Trypanocidal Effects of the Cyclopalladated Compound 7a, a Drug Candidate for Treatment of Chagas' Disease von MATSUO, Alisson L, SILVA, Luis S, TORRECILHAS, Ana C, PASCOALINO, Bruno S, RAMOS, Thiago C, RODRIGUES, Elaine G, SCHENKMAN, Sergio, CAIRES, Antonio C. F, TRAVASSOS, Luiz R

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Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery von Linciano, Pasquale, Dawson, Alice, Pöhner, Ina, Costa, David M, Sá, Monica S, Cordeiro-da-Silva, Anabela, Luciani, Rosaria, Gul, Sheraz, Witt, Gesa, Ellinger, Bernhard, Kuzikov, Maria, Gribbon, Philip, Reinshagen, Jeanette, Wolf, Markus, Behrens, Birte, Hannaert, Véronique, Michels, Paul A. M, Nerini, Erika, Pozzi, Cecilia, di Pisa, Flavio, Landi, Giacomo, Santarem, Nuno, Ferrari, Stefania, Saxena, Puneet, Lazzari, Sandra, Cannazza, Giuseppe, Freitas-Junior, Lucio H, Moraes, Carolina B, Pascoalino, Bruno S, Alcântara, Laura M, Bertolacini, Claudia P, Fontana, Vanessa, Wittig, Ulrike, Müller, Wolfgang, Wade, Rebecca C, Hunter, William N, Mangani, Stefano, Costantino, Luca, Costi, Maria P

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Drug Discovery for Human African Trypanosomiasis: Identification of Novel Scaffolds by the Newly Developed HTS SYBR Green Assay for Trypanosoma brucei von Faria, Joana, Moraes, Carolina B., Song, Rita, Pascoalino, Bruno S., Lee, Nakyung, Siqueira-Neto, Jair L., Cruz, Deu John M., Parkinson, Tanya, Ioset, Jean-Robert, Cordeiro-da-Silva, Anabela, Freitas-Junior, Lucio H.

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Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity von Franco, Caio H, Warhurst, David C, Bhattacharyya, Tapan, Au, Ho YA, Le, Hai, Giardini, Miriam A, Pascoalino, Bruno S, Torrecilhas, Ana Claudia, Romera, Lavinia MD, Madeira, Rafael Pedro, Schenkman, Sergio, Freitas-Junior, Lucio H, Chatelain, Eric, Miles, Michael A, Moraes, Carolina B

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Hydrocephalus and arthrogryposis in an immunocompetent mouse model of ZIKA teratogeny: A developmental study von Xavier-Neto, Jose, Carvalho, Murilo, Pascoalino, Bruno Dos Santos, Cardoso, Alisson Campos, Costa, Ângela Maria Sousa, Pereira, Ana Helena Macedo, Santos, Luana Nunes, Saito, Ângela, Marques, Rafael Elias, Smetana, Juliana Helena Costa, Consonni, Silvio Roberto, Bandeira, Carla, Costa, Vivian Vasconcelos, Bajgelman, Marcio Chaim, de Oliveira, Paulo Sérgio Lopes, Cordeiro, Marli Tenorio, Gonzales Gil, Laura Helena Vega, Pauletti, Bianca Alves, Granato, Daniela Campos, Paes Leme, Adriana Franco, Freitas-Junior, Lucio, Holanda de Freitas, Carolina Borsoi Moraes, Teixeira, Mauro Martins, Bevilacqua, Estela, Franchini, Kleber

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Multiplatform Single-Cell Analysis Identifies Immune Cell Types Enhanced in Pulmonary Fibrosis von Serezani, Ana P M, Pascoalino, Bruno D, Bazzano, Julia M R, Vowell, Katherine N, Tanjore, Harikrishna, Taylor, Chase J, Calvi, Carla L, McCall, A Scott, Bacchetta, Matthew D, Shaver, Ciara M, Ware, Lorraine B, Salisbury, Margaret L, Banovich, Nicholas E, Kendall, Peggy L, Kropski, Jonathan A, Blackwell, Timothy S

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Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein von Burman, Ankita, Kropski, Jonathan A, Calvi, Carla L, Serezani, Ana P, Pascoalino, Bruno D, Han, Wei, Sherrill, Taylor, Gleaves, Linda, Lawson, William E, Young, Lisa R, Blackwell, Timothy S, Tanjore, Harikrishna

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Reduction of Tubulin Expression in Angomonas deanei by RNAi Modifies the Ultrastructure of the Trypanosomatid Protozoan and Impairs Division of Its Endosymbiotic Bacterium von Catta-Preta, Carolina Moura Costa, dos Santos Pascoalino, Bruno, de Souza, Wanderley, Mottram, Jeremy C., Motta, Maria Cristina M., Schenkman, Sergio

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Sofosbuvir inhibits yellow fever virus in vitro and in patients with acute liver failure von Mendes, Érica Araújo, Pilger, Denise Regina Bairros de, Santos Nastri, Ana Catharina de Seixas, Malta, Fernanda de Mello, Pascoalino, Bruno dos Santos, Carneiro D’Albuquerque, Luiz Augusto, Balan, Andrea, Freitas, Lucio Holanda Gondim de, Durigon, Edison Luis, Carrilho, Flair José, Rebello Pinho, João Renato

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Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds von Borsari, Chiara, Santarem, Nuno, Torrado, Juan, Olías, Ana Isabel, Corral, María Jesús, Baptista, Catarina, Gul, Sheraz, Wolf, Markus, Kuzikov, Maria, Ellinger, Bernhard, Witt, Gesa, Gribbon, Philip, Reinshagen, Jeanette, Linciano, Pasquale, Tait, Annalisa, Costantino, Luca, Freitas-Junior, Lucio H., Moraes, Carolina B., Bruno dos Santos, Pascoalino, Alcântara, Laura Maria, Franco, Caio Haddad, Bertolacini, Claudia Danielli, Fontana, Vanessa, Tejera Nevado, Paloma, Clos, Joachim, Alunda, José María, Cordeiro-da-Silva, Anabela, Ferrari, Stefania, Costi, Maria Paola

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Expression of non-acetylatable lysines 10 and 14 of histone H4 impairs transcription and replication in Trypanosoma cruzi von Ramos, Thiago Cesar Prata, Nunes, Vinicius Santana, Nardelli, Sheila Cristina, dos Santos Pascoalino, Bruno, Moretti, Nilmar Silvio, Rocha, Antonio Augusto, da Silva Augusto, Leonardo, Schenkman, Sergio

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Kinetics characterization of a low immunogenic recombinant l-asparaginase from Phaseolus vulgaris with cytotoxic activity against leukemia cells von Gomes, José Gabriel da Silva, Brandão, Larisse Cadeira, Pinheiro, Daniel Pascoalino, Pontes, Larissa Queiroz, Carneiro, Rômulo Farias, Quintela, Bárbara Cibelle Soares Farias, Marinho, Anna Carolina Machado, Furtado, Gilvan Pessoa, Rocha, Bruno Anderson Matias

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Aryl thiosemicarbazones for the treatment of trypanosomatidic infections von Linciano, Pasquale, Moraes, Carolina B., Alcantara, Laura M., Franco, Caio H., Pascoalino, Bruno, Freitas-Junior, Lucio H., Macedo, Sara, Santarem, Nuno, Cordeiro-da-Silva, Anabela, Gul, Sheraz, Witt, Gesa, Kuzikov, Maria, Ellinger, Bernhard, Ferrari, Stefania, Luciani, Rosaria, Quotadamo, Antonio, Costantino, Luca, Costi, Maria Paola

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Effect of feed restriction on gene expression of bacterial enzymes produced in the rumen of Morada Nova lambs of different sex classes von Evangelista, Monalisa Eva Santos, Pinheiro, Daniel Pascoalino, da Silva, Bruno Bezerra, Pereira, Elzania Sales, Campos, Ana Cláudia Nascimento, Guedes, Maria Izabel Florindo, Pessoa, Claudia do Ó, Montenegro, Assis Rubens, Gadelha, Carla Renata Figueiredo

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Characterization of anti-silencing factor 1 in Leishmania major von Scher, Ricardo, Garcia, Juliana Bório Ferreira, Pascoalino, Bruno, Schenkman, Sergio, Cruz, Angela Kaysel

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Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform von Moraes, Carolina B., Witt, Gesa, Kuzikov, Maria, Ellinger, Bernhard, Calogeropoulou, Theodora, Prousis, Kyriakos C., Mangani, Stefano, Di Pisa, Flavio, Landi, Giacomo, Iacono, Lucia Dello, Pozzi, Cecilia, Freitas-Junior, Lucio H., dos Santos Pascoalino, Bruno, Bertolacini, Claudia P., Behrens, Birte, Keminer, Oliver, Leu, Jennifer, Wolf, Markus, Reinshagen, Jeanette, Cordeiro-da-Silva, Anabela, Santarem, Nuno, Venturelli, Alberto, Wrigley, Stephen, Karunakaran, Deepa, Kebede, Bethlehem, Pöhner, Ina, Müller, Wolfgang, Panecka-Hofman, Joanna, Wade, Rebecca C., Fenske, Martina, Clos, Joachim, Alunda, José María, Corral, María Jesús, Uliassi, Elisa, Bolognesi, Maria Laura, Linciano, Pasquale, Quotadamo, Antonio, Ferrari, Stefania, Santucci, Matteo, Borsari, Chiara, Costi, Maria Paola, Gul, Sheraz

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The Effects of the Alkaloid Tambjamine J on Mice Implanted with Sarcoma 180 Tumor Cells von Barros‐Nepomuceno, Francisco Washington A., Araújo Viana, Daniel, Pinheiro, Daniel Pascoalino, Cássia Evangelista de Oliveira, Fátima, Magalhães Ferreira, Jamile, R. de Queiroz, Maria Goretti, Ma, Xinghua, Cavalcanti, Bruno Coêlho, Pessoa, Claudia, Banwell, Martin G.

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Characterization of two different Asf1 histone chaperones with distinct cellular localizations and functions in Trypanosoma brucei von Pascoalino, Bruno, Dindar, Gülcin, Vieira-da-Rocha, João P, Machado, Carlos Renato, Janzen, Christian J, Schenkman, Sergio

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