Imidazoline-I2 PET Tracers in Neuroimaging von Parker, Christine A, Nutt, David J, Tyacke, Robin J

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An 18-kDa Translocator Protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28 von Owen, David R, Yeo, Astrid J, Gunn, Roger N, Song, Kijoung, Wadsworth, Graham, Lewis, Andrew, Rhodes, Chris, Pulford, David J, Bennacef, Idriss, Parker, Christine A, StJean, Pamela L, Cardon, Lon R, Mooser, Vincent E, Matthews, Paul M, Rabiner, Eugenii A, Rubio, Justin P

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Two binding sites for [ H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation von Owen, David R, Howell, Owain W, Tang, Sac-Pham, Wells, Lisa A, Bennacef, Idriss, Bergstrom, Mats, Gunn, Roger N, Rabiner, Eugenii A, Wilkins, Martin R, Reynolds, Richard, Matthews, Paul M, Parker, Christine A

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Sleep Duration Predicts Cardiometabolic Risk in Obese Adolescents von IglayReger, Heidi B., PhD, Peterson, Mark D., PhD, MS, Liu, Dongmei, PhD, Parker, Christine A., MS, Woolford, Susan J., MPH, MD, (Sallinen) Gafka, Bethany J., PhD, Hassan, Fauziya, MD, MS, Gordon, Paul M., PhD, MPH

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Combining PET Biodistribution and Equilibrium Dialysis Assays to Assess the Free Brain Concentration and BBB Transport of CNS Drugs von Gunn, Roger N, Summerfield, Scott G, Salinas, Cristian A, Read, Kevin D, Guo, Qi, Searle, Graham E, Parker, Christine A, Jeffrey, Phil, Laruelle, Marc

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Evaluation and initial in vitro and ex vivo characterization of the potential positron emission tomography ligand, BU99008 (2-(4,5-Dihydro-1H-imidazol-2-yl)-1- methyl-1H-indole), f... von Tyacke, Robin J., Fisher, Amy, Robinson, Emma S.J., Grundt, Peter, Turner, Emma M., Husbands, Stephen M., Hudson, Alan L., Parker, Christine A., Nutt, David J.

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Variation in binding affinity of the novel anxiolytic XBD173 for the 18 kDa translocator protein in human brain von Owen, David R.J., Lewis, Andrew J.M., Reynolds, Richard, Rupprecht, Rainer, Eser, Daniela, Wilkins, Martin R., Bennacef, Idriss, Nutt, David J., Parker, Christine A.

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Mixed-affinity binding in humans with 18-kDa translocator protein ligands von Owen, David R J, Gunn, Roger N, Rabiner, Eugenii A, Bennacef, Idriss, Fujita, Masahiro, Kreisl, William C, Innis, Robert B, Pike, Victor W, Reynolds, Richard, Matthews, Paul M, Parker, Christine A

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Astrocyte reactivity with late-onset cognitive impairment assessed in vivo using 11C-BU99008 PET and its relationship with amyloid load von Calsolaro, Valeria, Matthews, Paul M., Donat, Cornelius K., Livingston, Nicholas R., Femminella, Grazia D., Guedes, Sandra Silva, Myers, Jim, Fan, Zhen, Tyacke, Robin J., Venkataraman, Ashwin V., Perneczky, Robert, Gunn, Roger, Rabiner, Eugenii A., Gentleman, Steve, Parker, Christine A., Murphy, Philip S., Wren, Paul B., Hinz, Rainer, Sastre, Magdalena, Nutt, David J., Edison, Paul

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Quantitative Imaging of Regional Cerebral Protein Synthesis in Clinical Alzheimer's Disease by [11C]Leucine PET von Herholz, Karl, McMahon, Adam, Thompson, Jennifer C., Jones, Matthew, Boutin, Herve, Gregory, Jamil, Parker, Christine A., Hinz, Rainer

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First evaluation of PET-based human biodistribution and radiation dosimetry of 11C-BU99008, a tracer for imaging the imidazoline2 binding site von Venkataraman, Ashwin V., Keat, Nicholas, Myers, James F., Turton, Samuel, Mick, Inge, Gunn, Roger N., Rabiner, Eugenii A., Passchier, Jan, Parker, Christine A., Tyacke, Robin J., Nutt, David J.

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Degradative transport of cationic amphiphilic drugs across phospholipid bilayers von Baciu, Magdalena, Sebai, Sarra C, Ces, Oscar, Mulet, Xavier, Clarke, James A, Shearman, Gemma C, Law, Robert V, Templer, Richard H, Plisson, Christophe, Parker, Christine A, Gee, Antony

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Relationship between astrocyte reactivity, using novel 11C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals von Livingston, Nicholas R., Calsolaro, Valeria, Hinz, Rainer, Nowell, Joseph, Raza, Sanara, Gentleman, Steve, Tyacke, Robin J., Myers, Jim, Venkataraman, Ashwin V., Perneczky, Robert, Gunn, Roger N., Rabiner, Eugenii A., Parker, Christine A., Murphy, Philip S., Wren, Paul B., Nutt, David J., Matthews, Paul M., Edison, Paul

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Resolving the cellular specificity of TSPO imaging in a rat model of peripherally-induced neuroinflammation von Vicente-Rodríguez, Marta, Singh, Nisha, Turkheimer, Federico, Peris-Yague, Alba, Randall, Karen, Veronese, Mattia, Simmons, Camilla, Karim Haji-Dheere, Abdul, Bordoloi, Jayanta, Sander, Kerstin, Awais, Ramla O., Årstad, Erik, NIMA Consortium, Cash, Diana, Parker, Christine A.

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Imaging Endogenous Opioid Peptide Release with [11C]Carfentanil and [3H]Diprenorphine: Influence of Agonist-Induced Internalization von Quelch, Darren R, Katsouri, Loukia, Nutt, David J, Parker, Christine A, Tyacke, Robin J

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Synthesis and in vivo evaluation of [11C]BU99008 as a ligand for the imidazoline I2 binding site von Kealey, Steven, Husbands, Stephen, Casey, Emma M., Salinas, Cristian A., Parker, Christine A., Jakobsen, Steen, Tyacke, Robin J., Nutt, David J., Gee, Antony D.

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Preclinical evaluation of [18F]FB-A20FMDV2 as a selective marker for measuring αVβ6 integrin occupancy using positron emission tomography in rodent lung von Onega, Mayca, Parker, Christine A., Coello, Christopher, Rizzo, Gaia, Keat, Nicholas, Ramada-Magalhaes, Joaquim, Moz, Sara, Tang, Sac-Pham, Plisson, Christophe, Wells, Lisa, Ashworth, Sharon, Slack, Robert J., Vitulli, Giovanni, Wilson, Frederick J., Gunn, Roger, Lukey, Pauline T., Passchier, Jan

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Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease von Vicente-Rodríguez, Marta, Mancuso, Renzo, Peris-Yague, Alba, Simmons, Camilla, Gómez-Nicola, Diego, Perry, V Hugh, Turkheimer, Federico, Lovestone, Simon, Parker, Christine A, Cash, Diana

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Human Kinetic Modeling of the 5HT6 PET Radioligand 11C-GSK215083 and Its Utility for Determining Occupancy at Both 5HT6 and 5HT2A Receptors by SB742457 as a Potential Therapeutic M... von Parker, Christine A, Rabiner, Eugenii A, Gunn, Roger N, Searle, Graham, Martarello, Laurent, Comley, Robert A, Davy, Maria, Wilson, Alan A, Houle, Sylvain, Mizrahi, Romina, Laruelle, Marc, Cunningham, Vincent J

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Evaluation of 11C-BU99008, a PET Ligand for the Imidazoline2 Binding Site in Human Brain von Tyacke, Robin J, Myers, Jim F M, Venkataraman, Ashwin, Mick, Inge, Turton, Samuel, Passchier, Jan, Husbands, Stephen M, Rabiner, Eugenii A, Gunn, Roger N, Murphy, Philip S, Parker, Christine A, Nutt, David J

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