Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2 von Hornyak, Peter, Askwith, Trevor, Walker, Sarah, Komulainen, Emilia, Paradowski, Michael, Pennicott, Lewis E, Bartlett, Edward J, Brissett, Nigel C, Raoof, Ali, Watson, Mandy, Jordan, Allan M, Ogilvie, Donald J, Ward, Simon E, Atack, John R, Pearl, Laurence H, Caldecott, Keith W, Oliver, Antony W

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Neurosteroid Modulation of Synaptic and Extrasynaptic GABAA Receptors of the Mouse Nucleus Accumbens von Mitchell, Scott J., Phillips, Grant D., Tench, Becks, Li, Yunkai, Belelli, Delia, Martin, Stephen J., Swinny, Jerome D., Kelly, Louise, Atack, John R., Paradowski, Michael, Lambert, Jeremy J.

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African trypanosomiasis: Synthesis & SAR enabling novel drug discovery of ubiquinol mimics for trypanosome alternative oxidase von West, Ryan A., O'Doherty, Oran G., Askwith, Trevor, Atack, John, Beswick, Paul, Laverick, Jamie, Paradowski, Michael, Pennicott, Lewis E., Rao, Srinivasa P.S., Williams, Gareth, Ward, Simon E.

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Synthesis of the C1–C16 fragment of the ajudazols von Egan, Ben A., Paradowski, Michael, Thomas, Lynne H., Marquez, Rodolfo

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Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: A novel histamine H4 receptor antagonist von Mowbray, Charles E., Bell, Andrew S., Clarke, Nicholas P., Collins, Michelle, Jones, Rhys M., Lane, Charlotte A.L., Liu, Wai L., Newman, Sandra D., Paradowski, Michael, Schenck, Emanuel J., Selby, Mathew D., Swain, Nigel A., Williams, David H.

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Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion von Cockerill, G. Stuart, Angell, Richard M, Bedernjak, Alexandre, Chuckowree, Irina, Fraser, Ian, Gascon-Simorte, Jose, Gilman, Morgan S. A, Good, James A. D, Harland, Rachel, Johnson, Sara M, Ludes-Meyers, John H, Littler, Edward, Lumley, James, Lunn, Graham, Mathews, Neil, McLellan, Jason S, Paradowski, Michael, Peeples, Mark E, Scott, Claire, Tait, Dereck, Taylor, Geraldine, Thom, Michelle, Thomas, Elaine, Villalonga Barber, Carol, Ward, Simon E, Watterson, Daniel, Williams, Gareth, Young, Paul, Powell, Kenneth

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Regiocontrolled Rearrangement of Isobenzofurans von Egan, Ben A, Paradowski, Michael, Thomas, Lynne H, Marquez, Rodolfo

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An atom-efficient and convergent approach to the preparation of NS5A inhibitors by C-H activation von Moore, Thomas O, Paradowski, Michael, Ward, Simon E

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A challenge finding P2X1 and P2X4 ligands von Beswick, Paul, Wahab, Ben, Honey, Mark A., Paradowski, Michael, Jiang, Ke, Lochner, Martin, Murrell-Lagnado, Ruth D., Thompson, Andrew J.

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Incorporation by coordination and release of the iron chelator drug deferiprone from zinc-based metal-organic frameworks von Burrows, Andrew D, Jurcic, Monika, Keenan, Luke L, Lane, Rebecca A, Mahon, Mary F, Warren, Mark R, Nowell, Harriott, Paradowski, Michael, Spencer, John

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Neurosteroid Modulation of Synaptic and Extrasynaptic GABA A Receptors of the Mouse Nucleus Accumbens von Mitchell, Scott J, Phillips, Grant D, Tench, Becks, Li, Yunkai, Belelli, Delia, Martin, Stephen J, Swinny, Jerome D, Kelly, Louise, Atack, John R, Paradowski, Michael, Lambert, Jeremy J

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Group Decision-Making on an Optimal Stopping Problem von Lee, Michael D, Paradowski, Michael J, Lee, Michael D, Paradowski, Michael J

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Incorporation by coordination and release of the iron chelator drug deferiprone from zinc-based metal-organic frameworksElectronic supplementary information (ESI) available: CCDC 9... von Burrows, Andrew D, Jurcic, Monika, Keenan, Luke L, Lane, Rebecca A, Mahon, Mary F, Warren, Mark R, Nowell, Harriott, Paradowski, Michael, Spencer, John

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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile-Part 1 von Tran, Thien Duc, Wakenhut, Florian, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Brimage, Rebecca A., Halstead, Rebecca, Glen, Rebecca, Wilson, Craig P., Adam, Fiona, Hay, Duncan, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C., Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C.

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Synthesis of novel histamine H4 receptor antagonists von Lane, Charlotte A.L., Hay, Duncan, Mowbray, Charles E., Paradowski, Michael, Selby, Matthew D., Swain, Nigel A., Williams, David H.

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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile-Part 2 von Wakenhut, Florian, Tran, Thien Duc, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Stonehouse, David, Cheung, Kathy, Wybrow, Robert, Daverio, Felice, Crook, Samuel, Statham, Keith, Leese, David, Stead, Darren, Adam, Fiona, Hay, Duncan, Roberts, Lee R., Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C., Goetz, Gilles H., Che, Ye, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C.

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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile--Part2 von Wakenhut, Florian, Tran, Thien Duc, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Stonehouse, David, Cheung, Kathy, Wybrow, Robert, Daverio, Felice, Crook, Samuel, Statham, Keith, Leese, David, Stead, Darren, Adam, Fiona, Hay, Duncan, Roberts, Lee R, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C, Goetz, Gilles H, Che, Ye, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C

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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile--Part1 von Tran, Thien Duc, Wakenhut, Florian, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Brimage, Rebecca A, Halstead, Rebecca, Glen, Rebecca, Wilson, Craig P, Adam, Fiona, Hay, Duncan, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C

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Using task analysis to improve usability of fatigue modelling software von Paradowski, Michael, Fletcher, Adam

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A flexible synthesis of C-6 and N-1 analogues of a 4-amino-1,3-dihydroimidazo[4,5- c]pyridin-2-one core von Hay, Duncan A., Adam, Fiona M., Bish, Gerwyn, Calo, Frederick, Dixon, Rachel, Fray, M. Jonathan, Hitchin, James, Jones, Peter, Paradowski, Michael, Parsons, Gemma C., Proctor, Katie J.W., Pryde, David C., Smith, Nicholas N., Tran, Thien-Duc

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