Exhausted cytotoxic control of Epstein-Barr virus in human lupus von Larsen, Martin, Sauce, Delphine, Deback, Claire, Arnaud, Laurent, Mathian, Alexis, Miyara, Makoto, Boutolleau, David, Parizot, Christophe, Dorgham, Karim, Papagno, Laura, Appay, Victor, Amoura, Zahir, Gorochov, Guy

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Naïve CD8 + T-Cells Engage a Versatile Metabolic Program Upon Activation in Humans and Differ Energetically From Memory CD8 + T-Cells von Nicoli, Francesco, Papagno, Laura, Frere, Justin J, Cabral-Piccin, Mariela Pires, Clave, Emmanuel, Gostick, Emma, Toubert, Antoine, Price, David A, Caputo, Antonella, Appay, Victor

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Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses von Gutjahr, Alice, Papagno, Laura, Nicoli, Francesco, Lamoureux, Alain, Vernejoul, Fabienne, Lioux, Thierry, Gostick, Emma, Price, David A, Tiraby, Gérard, Perouzel, Eric, Appay, Victor, Verrier, Bernard, Paul, Stéphane

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New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses von Gutjahr, Alice, Papagno, Laura, Vernejoul, Fabienne, Lioux, Thierry, Jospin, Fabienne, Chanut, Blandine, Perouzel, Eric, Rochereau, Nicolas, Appay, Victor, Verrier, Bernard, Paul, Stéphane

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Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection von Papagno, Laura, Spina, Celsa A, Marchant, Arnaud, Salio, Mariolina, Rufer, Nathalie, Little, Susan, Dong, Tao, Chesney, Gillian, Waters, Anele, Easterbrook, Philippa, Dunbar, P Rod, Shepherd, Dawn, Cerundolo, Vincenzo, Emery, Vincent, Griffiths, Paul, Conlon, Christopher, McMichael, Andrew J, Richman, Douglas D, Rowland-Jones, Sarah L, Appay, Victor

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Characterization of CD4+ CTLs Ex Vivo von Appay, Victor, Zaunders, John J, Papagno, Laura, Sutton, Julian, Jaramillo, Angel, Waters, Anele, Easterbrook, Philippa, Grey, Pat, Smith, Don, McMichael, Andrew J, Cooper, David A, Rowland-Jones, Sarah L, Kelleher, Anthony D

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Elderly human hematopoietic progenitor cells express cellular senescence markers and are more susceptible to pyroptosis von Fali, Tinhinane, Fabre-Mersseman, Véronique, Yamamoto, Takuya, Bayard, Charles, Papagno, Laura, Fastenackels, Solène, Zoorab, Rima, Koup, Richard A, Boddaert, Jacques, Sauce, Delphine, Appay, Victor

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New Insights into Lymphocyte Differentiation and Aging from Telomere Length and Telomerase Activity Measurements von Fali, Tinhinane, Papagno, Laura, Bayard, Charles, Mouloud, Yanis, Boddaert, Jacques, Sauce, Delphine, Appay, Victor

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17 Priming of tumour or HIV-specific human CD8+ T cells with superior functional properties using STING ligands von Papagno, Laura, Nicoli, Francesco, Kuse, Nozomi, Gutjahr, Alice, Tiraby, Gerard, Verrier, Bernard, Paul, Stéphane, Takiguchi, Masafumi, Appay, Victor

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Upregulation of Interleukin 7 Receptor Alpha and Programmed Death 1 Marks an Epitope-Specific CD8+ T-Cell Response That Disappears following Primary Epstein-Barr Virus Infection von SAUCE, Delphine, LARSEN, Martin, ABBOTT, Rachel J. M, HISLOP, Andrew D, LEESE, Alison M, KHAN, Naeem, PAPAGNO, Laura, FREEMAN, Gordon J, RICKINSON, Alan B

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Neurological Symptoms during Primary Human Immunodeficiency Virus (HIV) Infection Correlate with High Levels of HIV RNA in Cerebrospinal Fluid von Tambussi, Giuseppe, Gori, Andrea, Capiluppi, Brunella, Balotta, Claudia, Papagno, Laura, Morandini, Barbara, Di Pietro, Massimo, Ciuffreda, Donatella, Saracco, Alberto, Lazzarin, Adriano

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Reduced naïve CD8+ T‐cell priming efficacy in elderly adults von Briceño, Olivia, Lissina, Anna, Wanke, Kerstin, Afonso, Georgia, Braun, Amrei, Ragon, Kristanto, Miquel, Tiphaine, Gostick, Emma, Papagno, Laura, Stiasny, Karin, Price, David A., Mallone, Roberto, Sauce, Delphine, Karrer, Urs, Appay, Victor

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Impact of IgA isoforms on their ability to activate dendritic cells and to prime T cells von Gayet, Rémi, Michaud, Eva, Nicoli, Francesco, Chanut, Blandine, Paul, Mireille, Rochereau, Nicolas, Guillon, Christophe, He, Zhiguo, Papagno, Laura, Bioley, Gilles, Corthesy, Blaise, Paul, Stéphane

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Treatment intensification followed by interleukin-7 reactivates HIV without reducing total HIV DNA: a randomized trial von Katlama, Christine, Lambert-Niclot, Sidonie, Assoumou, Lambert, Papagno, Laura, Lecardonnel, François, Zoorob, Rima, Tambussi, Giuseppe, Clotet, Bonaventura, Youle, Mike, Achenbach, Chad J, Murphy, Robert L, Calvez, Vincent, Costagliola, Dominique, Autran, Brigitte

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Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8 + T Cells in Elderly Humans von Nicoli, Francesco, Cabral-Piccin, Mariela P, Papagno, Laura, Gallerani, Eleonora, Fusaro, Mathieu, Folcher, Victor, Dubois, Marion, Clave, Emmanuel, Vallet, Hélène, Frere, Justin J, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A, Toubert, Antoine, Dupré, Loïc, Boddaert, Jacques, Caputo, Antonella, Gavioli, Riccardo, Appay, Victor

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Accelerated immune senescence and HIV-1 infection von Appay, Victor, Almeida, Jorge R., Sauce, Delphine, Autran, Brigitte, Papagno, Laura

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The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro von Papagno, Laura, Kuse, Nozomi, Lissina, Anna, Gostick, Emma, Price, David A., Appay, Victor, Nicoli, Francesco

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Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover von Almeida, Jorge R, Price, David A, Papagno, Laura, Arkoub, Zaïna Aït, Sauce, Delphine, Bornstein, Ethan, Asher, Tedi E, Samri, Assia, Schnuriger, Aurélie, Theodorou, Ioannis, Costagliola, Dominique, Rouzioux, Christine, Agut, Henri, Marcelin, Anne-Geneviève, Douek, Daniel, Autran, Brigitte, Appay, Victor

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Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1 von White, Eoghann, Papagno, Laura, Samri, Assia, Sugata, Kenji, Hejblum, Boris, Henry, Amy R., Rogan, Daniel C., Darko, Samuel, Recordon-Pinson, Patricia, Dudoit, Yasmine, Llewellyn-Lacey, Sian, Chakrabarti, Lisa A., Buseyne, Florence, Migueles, Stephen A., Price, David A., Andreola, Marie-Aline, Satou, Yorifumi, Thiebaut, Rodolphe, Katlama, Christine, Autran, Brigitte, Douek, Daniel C., Appay, Victor

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Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity von Almeida, Jorge R., Sauce, Delphine, Price, David A., Papagno, Laura, Shin, So Youn, Moris, Arnaud, Larsen, Martin, Pancino, Gianfranco, Douek, Daniel C., Autran, Brigitte, Sáez-Cirión, Asier, Appay, Victor

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