Intratumoral Heterogeneity of the Epigenome von Mazor, Tali, Pankov, Aleksandr, Song, Jun S., Costello, Joseph F.

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DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors von Mazor, Tali, Pankov, Aleksandr, Johnson, Brett E., Hong, Chibo, Hamilton, Emily G., Bell, Robert J.A., Smirnov, Ivan V., Reis, Gerald F., Phillips, Joanna J., Barnes, Michael J., Idbaih, Ahmed, Alentorn, Agusti, Kloezeman, Jenneke J., Lamfers, Martine L.M., Bollen, Andrew W., Taylor, Barry S., Molinaro, Annette M., Olshen, Adam B., Chang, Susan M., Song, Jun S., Costello, Joseph F.

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G-Convergence and Homogenization of Nonlinear Partial Differential Operators von Hazewinkel, M, Pankov, Alexander

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Data-driven regions of interest for longitudinal change in frontotemporal lobar degeneration von Pankov, Aleksandr, Binney, Richard J, Staffaroni, Adam M, Kornak, John, Attygalle, Suneth, Schuff, Norbert, Weiner, Michael W, Kramer, Joel H, Dickerson, Bradford C, Miller, Bruce L, Rosen, Howard J

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Bounded and Almost Periodic Solutions of Nonlinear Operator Differential Equations von Pankov, A. A

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NF45 and NF90/NF110 coordinately regulate ESC pluripotency and differentiation von Ye, Julia, Jin, Hu, Pankov, Aleksandr, Song, Jun S, Blelloch, Robert

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Abstract LB-A10: ORIC-101 overcomes glucocorticoid-driven resistance to enzalutamide in castration-resistant prostate cancer von Zhou, Haiying, Barkund, Shravani, Pankov, Aleksandr, Sinha, Sharvani, Sutimantanapi, Dena, Friedman, Lori S., Kabbarah, Omar

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Abstract 4120: ORIC-101 comprehensively inhibits glucocorticoid pathways to overcome therapeutic resistance in pan-cancer models von Pankov, Aleksandr, Zhou, Haiying, Barkund, Shravani, Hegde, Ganapati, Narayanan, Padmini, Kabbarah, Omar, Friedman, Lori S., Daemen, Anneleen

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Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1 von Mazor, Tali, Chesnelong, Charles, Pankov, Aleksandr, Jalbert, Llewellyn E., Hong, Chibo, Hayes, Josie, Smirnov, Ivan V., Marshall, Roxanne, Souza, Camila F., Shen, Yaoqing, Viswanath, Pavithra, Noushmehr, Houtan, Ronen, Sabrina M., Jones, Steven J. M., Marra, Marco A., Cairncross, J. Gregory, Perry, Arie, Nelson, Sarah J., Chang, Susan M., Bollen, Andrew W., Molinaro, Annette M., Bengtsson, Henrik, Olshen, Adam B., Weiss, Samuel, Phillips, Joanna J., Luchman, H. Artee, Costello, Joseph F.

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Abstract P6-03-24: ORIC-101 robustly inhibits the glucocorticoid pathway and overcomes chemoresistance in triple-negative breast cancer von Zhou, Haiying, Ye, Qiuping, Pankov, Aleksandr, Kong, Wayne, Barkund, Shravani, Friedman, Lori S., Sun, Jessica D., Kabbarah, Omar

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Abstract P015: Biomarker results supporting selection of RP2D from a phase 1b study of ORIC-101, a glucocorticoid receptor antagonist, in combination with enzalutamide in patients... von Daemen, Anneleen, Barkund, Shravani, Johnson, Ann, Pankov, Aleksandr, Wang, Amber W., Zhou, Haiying, Multani, Pratik S., Maneval, Edna Chow, Friedman, Lori S., Patel, Rupal

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Biomarker results supporting selection of RP2D from a phase 1b study of ORIC-101, a glucocorticoid receptor antagonist, in combination with nab-paclitaxel in patients with advanced... von Daemen, Anneleen, Pankov, Aleksandr, Barkund, Shravani, Zhou, Haiying, Duff, Maureen, Johnson, Ann, Xu, Rongda, Multani, Pratik S., Chow Maneval, Edna, Friedman, Lori

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Abstract IA08: An epigenome perspective of human tumor evolution von Mazor, Tali, Pankov, Aleksandr, Song, Jun, Costello, Joseph

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Abstract 4121: ORIC-101 overcomes resistance to diverse chemotherapeutics across cancer types von Zhou, Haiying, Barkund, Shravani, Pankov, Aleksandr, Hegde, Ganapati, Kong, Wayne, Narayanan, Padmini, Sun, Jessica D., Kabbarah, Omar, Friedman, Lori S., Daemen, Anneleen

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Abstract 5363: Measuring gene expression at the tumor microenvironment: A comparison between nCounter PanCancer Immune Profiling Panel and Oncomine Immune Response Research Assay von Mongan, Ann, Tom, Warren, Au-Young, Janice, Pankov, Aleksandr, Ganpule, Gauri, Hyland, Fiona

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Abstract 2267: A novel method for classification of microsatellite instability (MSI) using the Oncomine Tumor Mutation Load assay von Pankov, Aleksandr, El-Difrawy, Sameh, Tom, Warren, Conroy, Jeffrey, Glenn, Sean, Pabla, Sarabjot, Morrison, Carl, Hyland, Fiona, Cawley, Simon

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Abstract 4123: ORIC-101 overcomes glucocorticoid receptor-mediated chemoresistance in pancreatic cancer models von Sun, Jessica D., Zhou, Haiying, Kong, Wayne, Yuen, Natalie, Duong, Frank L., Barkund, Shravani, Pankov, Aleksandr, McWeeney, Dan, Ye, Qiuping, Kabbarah, Omar, Friedman, Lori S., Daemen, Anneleen, Junttila, Melissa

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Abstract 1131: ORIC-944, a potent and selective allosteric PRC2 inhibitor, demonstrates robust in vivo activity in prostate cancer models von Daemen, Anneleen, Sun, Jessica D., Pankov, Aleksandr, Duong, Frank L., Yuen, Natalie, Barkund, Shravani, Kaushik, Shelly, Chang, Jae H., Briere, David M., Sudhakar, Niranjan, Calinisan, Andrew, Burns, Aaron, Ketcham, John M., Marx, Matthew A., Olson, Peter, Christensen, James G., Junttila, Melissa R., Friedman, Lori S.

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Verification of targeted gene expression profiling panel for identifying biomarker signatures for immunotherapy research von Pankov, Aleksandr, Ku, Yuan-Chieh, Tom, Warren, Zheng, Jianping, Sun, Yongming, Looney, Timothy, Au-Young, Janice, Mongan, Ann, Hyland, Fiona

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Mutant IDH1 expression is associated with down-regulation of monocarboxylate transporters von Viswanath, Pavithra, Najac, Chloe, Izquierdo-Garcia, Jose L, Pankov, Aleksandr, Hong, Chibo, Eriksson, Pia, Costello, Joseph F, Pieper, Russell O, Ronen, Sabrina M

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