Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo von Pusch, Stefan, Krausert, Sonja, Fischer, Viktoria, Balss, Jörg, Ott, Martina, Schrimpf, Daniel, Capper, David, Sahm, Felix, Eisel, Jessica, Beck, Ann-Christin, Jugold, Manfred, Eichwald, Viktoria, Kaulfuss, Stefan, Panknin, Olaf, Rehwinkel, Hartmut, Zimmermann, Katja, Hillig, Roman C., Guenther, Judith, Toschi, Luisella, Neuhaus, Roland, Haegebart, Andrea, Hess-Stumpp, Holger, Bauser, Markus, Wick, Wolfgang, Unterberg, Andreas, Herold-Mende, Christel, Platten, Michael, von Deimling, Andreas

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Synergistic activity of IDH1 inhibitor BAY1436032 with azacitidine in IDH1 mutant acute myeloid leukemia von Chaturvedi, Anuhar, Gupta, Charu, Gabdoulline, Razif, Borchert, Nora M, Goparaju, Ramya, Kaulfuss, Stefan, Görlich, Kerstin, Schottmann, Renate, Othman, Basem, Welzenbach, Julia, Panknin, Olaf, Wagner, Markus, Geffers, Robert, Ganser, Arnold, Thol, Felicitas, Jeffers, Michael, Haegebarth, Andrea, Heuser, Michael

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Lewis Acid Mediated Asymmetric [2,3]-Sigmatropic Rearrangement of Allylic Amines. Scope and Mechanistic Investigation von Blid, Jan, Panknin, Olaf, Tuzina, Pavel, Somfai, Peter

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Asymmetric [2,3]-Sigmatropic Rearrangement of Allylic Ammonium Ylides von Blid, Jan, Panknin, Olaf, Somfai, Peter

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Discovery and Characterization of BAY 1214784, an Orally Available Spiroindoline Derivative Acting as a Potent and Selective Antagonist of the Human Gonadotropin-Releasing Hormone... von Panknin, Olaf, Wagenfeld, Andrea, Bone, Wilhelm, Bender, Eckhard, Nowak-Reppel, Katrin, Fernández-Montalván, Amaury E, Nubbemeyer, Reinhard, Bäurle, Stefan, Ring, Sven, Schmees, Norbert, Prien, Olaf, Schäfer, Martina, Friedrich, Christian, Zollner, Thomas M, Steinmeyer, Andreas, Mueller, Thomas, Langer, Gernot

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Investigations of the [2,3]-Sigmatropic Rearrangements of Vinylaziridines and Allylic Amines von Somfai, Peter, Panknin, Olaf

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Efficacy of Chemotherapy, Phd-Inhibitor Molidustat or BRD4 Inhibitor JQ1 in Combination with Targeted Inhibition of Mutated IDH1 in Human AML In Vivo von Chaturvedi, Anuhar, Gupta, Charu, Kaulfuss, Stefan, Othman, Basem, Görlich, Kerstin, Schottmann, Renate, Panknin, Olaf, Wagner, Markus, Ganser, Arnold, Jeffers, Michael, Haegebarth, Andrea, Heuser, Michael

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Synthesis of Aryl Glycines by the α Arylation of Weinreb Amides von Hirner, Sebastian, Panknin, Olaf, Edefuhr, Magnus, Somfai, Peter

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Synergistic Activity of IDH1 Inhibitor Bay-1436032 with Azacitidine in IDH1 Mutant Acute Myeloid Leukemia von Chaturvedi, Anuhar, Gupta, Charu, Goparaju, Ramya, Gabdoulline, Razif, Kaulfuss, Stefan, Görlich, Kerstin, Schottmann, Renate, Panknin, Olaf, Wagner, Markus, Geffers, Robert, Ganser, Arnold, Thol, Felicitas, Jeffers, Michael, Haegebarth, Andrea, Heuser, Michael

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Abstract 2645: BAY 1436032: A highly selective, potent and orally available inhibitor of mutant forms of IDH1 von Panknin, Olaf, Pusch, Stefan, Herbst, Lena, Kaulfuss, Stefan, Zimmermann, Katja, Rehwinkel, Hartmut, Neuhaus, Roland, Ring, Sven, Brüning, Michael, Stark, Claudia, Prelle, Katja, Michels, Martin, Jeffers, Michael, Hess-Stumpp, Holger, Ziegelbauer, Karl, Brands, Michael, Krämer, Alwin, von Deimling, Andreas

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Investigations of the 2,3 -sigmatropic rearrangements of vinylaziridines and allylic amines von Somfai, Peter, Panknin, Olaf

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Pan-Mutant-IDH1 Inhibitor Bay-1436032 Is Highly Effective Against Human IDH1 Mutant Acute Myeloid Leukemia In Vivo von Heuser, Michael, Herbst, Lena, Pusch, Stefan, Klett, Lara, Goparaju, Ramya, Stichel, Damian, Kaulfuss, Stefan, Panknin, Olaf, Zimmermann, Katja, Toschi, Luisella, Neuhaus, Roland, Haegebarth, Andrea, Rehwinkel, Hartmut, Hess-Stumpp, Holger, Bauser, Markus, Bochtler, Tilmann, Struys, Eduard A, Sharma, Amit, Abdellatif, Abdellatif, Geffers, Robert, Araujo Cruz, Michelle M, Thol, Felicitas, Gabdoulline, Razif, Ganser, Arnold, Ho, Anthony D, von Deimling, Andreas, Rippe, Karsten, Chaturvedi, Anuhar, Kraemer, Alwin

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Synthesis of a Novel Pentagastrin-Drug Conjugate for a Targeted Tumor Therapy von Tietze, Lutz F., Panknin, Olaf, Major, Felix, Krewer, Birgit

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Synthesis of New Sugar-Based Surfactants and Evaluation of Their Hemolytic Activities von Neimert-Andersson, Kristina, Sauer, Sven, Panknin, Olaf, Borg, Tessie, Söderlind, Erik, Somfai, Peter

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Synthesis and Biological Evaluation of a Novel Pentagastrin- Toxin Conjugate Designed for a Targeted Prodrug Monotherapy of Cancer von Tietze, Lutz F., Panknin, Olaf, Krewer, Birgit, Major, Felix, Schuberth, Ingrid

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Lewis acid mediated asymmetric 2,3 -sigmatropic rearrangement of allylic amines. Scope and mechanistic investigation von Blid, Jan, Panknin, Olaf, Tuzina, Pavel, Somfai, Peter

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Proof of Principle in the Selective Treatment of Cancer by Antibody-Directed Enzyme Prodrug Therapy: The Development of a Highly Potent Prodrug von Tietze, Lutz F., Feuerstein, Tim, Fecher, Anja, Haunert, Frank, Panknin, Olaf, Borchers, Ulrich, Schuberth, Ingrid, Alves, Frauke

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2-ARYL- AND 2-ARYLALKYL-BENZIMIDAZOLES AS MIDH1 INHIBITORS von PANKNIN, Olaf, ZIMMERMANN, Katja, NEUHAUS, Roland

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Synthesis of Aryl Glycines by the α Arylation of Weinreb Amides von Hirner, Sebastian, Panknin, Olaf, Edefuhr, Magnus, Somfai, Peter

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High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging von Panknin, Olaf, Lohrke, Jessica, Jost, Gregor, Berger, Markus, Frenzel, Thomas, Hilger, Christoph-Stephan, Pietsch, Hubertus

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