Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy von Scaramuzzino, Chiara, Casci, Ian, Parodi, Sara, Lievens, Patricia M J, Polanco, Maria J, Milioto, Carmelo, Chivet, Mathilde, Monaghan, John, Mishra, Ashutosh, Badders, Nisha, Aggarwal, Tanya, Grunseich, Christopher, Sambataro, Fabio, Basso, Manuela, Fackelmayer, Frank O, Taylor, J Paul, Pandey, Udai Bhan, Pennuto, Maria

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Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization von Casci, Ian, Krishnamurthy, Karthik, Kour, Sukhleen, Tripathy, Vadreenath, Ramesh, Nandini, Anderson, Eric N., Marrone, Lara, Grant, Rogan A., Oliver, Stacie, Gochenaur, Lauren, Patel, Krishani, Sterneckert, Jared, Gleixner, Amanda M., Donnelly, Christopher J., Ruepp, Marc-David, Sini, Antonella M., Zuccaro, Emanuela, Pennuto, Maria, Pasinelli, Piera, Pandey, Udai Bhan

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Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand von Ramesh, Nandini, Pandey, Udai Bhan

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Stress granules at the intersection of autophagy and ALS von Monahan, Zachary, Shewmaker, Frank, Pandey, Udai Bhan

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Editorial: Drosophila as a model to study neurodegenerative diseases von Liguori, Francesco, Pandey, Udai Bhan, Digilio, Filomena Anna

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RNP-Granule Assembly via Ataxin-2 Disordered Domains Is Required for Long-Term Memory and Neurodegeneration von Bakthavachalu, Baskar, Huelsmeier, Joern, Sudhakaran, Indulekha P., Hillebrand, Jens, Singh, Amanjot, Petrauskas, Arnas, Thiagarajan, Devasena, Sankaranarayanan, M., Mizoue, Laura, Anderson, Eric N., Pandey, Udai Bhan, Ross, Eric, VijayRaghavan, K., Parker, Roy, Ramaswami, Mani

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FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy von Marrone, Lara, Drexler, Hannes C. A., Wang, Jie, Tripathi, Priyanka, Distler, Tania, Heisterkamp, Patrick, Anderson, Eric Nathaniel, Kour, Sukhleen, Moraiti, Anastasia, Maharana, Shovamayee, Bhatnagar, Rajat, Belgard, T. Grant, Tripathy, Vadreenath, Kalmbach, Norman, Hosseinzadeh, Zohreh, Crippa, Valeria, Abo-Rady, Masin, Wegner, Florian, Poletti, Angelo, Troost, Dirk, Aronica, Eleonora, Busskamp, Volker, Weis, Joachim, Pandey, Udai Bhan, Hyman, Anthony A., Alberti, Simon, Goswami, Anand, Sterneckert, Jared

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Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo von Gogia, Neha, Sarkar, Ankita, Mehta, Abijeet Singh, Ramesh, Nandini, Deshpande, Prajakta, Kango-Singh, Madhuri, Pandey, Udai Bhan, Singh, Amit

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The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity von Crippa, Valeria, Cicardi, Maria Elena, Ramesh, Nandini, Seguin, Samuel J, Ganassi, Massimo, Bigi, Ilaria, Diacci, Chiara, Zelotti, Elena, Baratashvili, Madina, Gregory, Jenna M, Dobson, Christopher M, Cereda, Cristina, Pandey, Udai Bhan, Poletti, Angelo, Carra, Serena

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HuD impairs neuromuscular junctions and induces apoptosis in human iPSC and Drosophila ALS models von Silvestri, Beatrice, Mochi, Michela, Mawrie, Darilang, de Turris, Valeria, Colantoni, Alessio, Borhy, Beatrice, Medici, Margherita, Anderson, Eric Nathaniel, Garone, Maria Giovanna, Zammerilla, Christopher Patrick, Simula, Marco, Ballarino, Monica, Pandey, Udai Bhan, Rosa, Alessandro

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Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans von Rudich, Paige, Snoznik, Carley, Watkins, Simon C, Monaghan, John, Pandey, Udai Bhan, Lamitina, S Todd

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HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS von Pandey, Udai Bhan, Nie, Zhiping, Batlevi, Yakup, McCray, Brett A., Ritson, Gillian P., Nedelsky, Natalia B., Schwartz, Stephanie L., DiProspero, Nicholas A., Knight, Melanie A., Schuldiner, Oren, Padmanabhan, Ranjani, Hild, Marc, Berry, Deborah L., Garza, Dan, Hubbert, Charlotte C., Yao, Tso-Pang, Baehrecke, Eric H., Taylor, J. Paul

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Matrin-3 dysfunction in myopathy and motor neuron degeneration von Ward, Caroline, Pandey, Udai

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RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM von Ramesh, Nandini, Kour, Sukhleen, Anderson, Eric N, Rajasundaram, Dhivyaa, Pandey, Udai Bhan

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A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43 von LANSON JR, Nicholas A, MALTARE, Astha, KING, Hanna, SMITH, Rebecca, JI HAN KIM, PAUL TAYLOR, J, LLOYD, Thomas E, BHAN PANDEY, Udai

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LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice von Prakasam, Ramachandran, Bonadiman, Angela, Andreotti, Roberta, Zuccaro, Emanuela, Dalfovo, Davide, Marchioretti, Caterina, Tripathy, Debasmita, Petris, Gianluca, Anderson, Eric N., Migazzi, Alice, Tosatto, Laura, Cereseto, Anna, Battaglioli, Elena, Sorarù, Gianni, Lim, Wooi Fang, Rinaldi, Carlo, Sambataro, Fabio, Pourshafie, Naemeh, Grunseich, Christopher, Romanel, Alessandro, Pandey, Udai Bhan, Contestabile, Andrea, Ronzitti, Giuseppe, Basso, Manuela, Pennuto, Maria

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Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology von Anderson, Eric N, Morera, Andrés A, Kour, Sukhleen, Cherry, Jonathan D, Ramesh, Nandini, Gleixner, Amanda, Schwartz, Jacob C, Ebmeier, Christopher, Old, William, Donnelly, Christopher J, Cheng, Jeffrey P, Kline, Anthony E, Kofler, Julia, Stein, Thor D, Pandey, Udai Bhan

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Mutation-dependent aggregation and toxicity in a Drosophila model for UBQLN2-associated ALS von Kim, Sang Hwa, Stiles, Shannon G, Feichtmeier, Joseph M, Ramesh, Nandini, Zhan, Lihong, Scalf, Mark A, Smith, Lloyd M, Pandey, Udai Bhan, Tibbetts, Randal S

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Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo von Scaramuzzino, Chiara, Monaghan, John, Milioto, Carmelo, Lanson, Jr, Nicholas A, Maltare, Astha, Aggarwal, Tanya, Casci, Ian, Fackelmayer, Frank O, Pennuto, Maria, Pandey, Udai Bhan

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Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy von Marrone, Lara, Poser, Ina, Casci, Ian, Japtok, Julia, Reinhardt, Peter, Janosch, Antje, Andree, Cordula, Lee, Hyun O., Moebius, Claudia, Koerner, Ellen, Reinhardt, Lydia, Cicardi, Maria Elena, Hackmann, Karl, Klink, Barbara, Poletti, Angelo, Alberti, Simon, Bickle, Marc, Hermann, Andreas, Pandey, Udai Bhan, Hyman, Anthony A., Sterneckert, Jared L.

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