Mechanisms and optimization of in vivo delivery of lipophilic siRNAs von Stoffel, Markus, Wolfrum, Christian, Shi, Shuanping, Jayaprakash, K Narayanannair, Jayaraman, Muthusamy, Wang, Gang, Pandey, Rajendra K, Rajeev, Kallanthottathil G, Nakayama, Tomoko, Charrise, Klaus, Ndungo, Esther M, Zimmermann, Tracy, Koteliansky, Victor, Manoharan, Muthiah

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Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA von Pallan, Pradeep S, Greene, Emily M, Jicman, Paul Andrei, Pandey, Rajendra K, Manoharan, Muthiah, Rozners, Eriks, Egli, Martin

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Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B von Korolowicz, Kyle E, Iyer, Radhakrishnan P, Czerwinski, Stefanie, Suresh, Manasa, Yang, Junming, Padmanabhan, Seetharamaiyer, Sheri, Anjaneyulu, Pandey, Rajendra K, Skell, Jeffrey, Marquis, Judith K, Kallakury, Bhaskar V, Tucker, Robin D, Menne, Stephan

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs von Soutschek, Jürgen, Akinc, Akin, Bramlage, Birgit, Charisse, Klaus, Constien, Rainer, Donoghue, Mary, Elbashir, Sayda, Geick, Anke, Hadwiger, Philipp, Harborth, Jens, John, Matthias, Kesavan, Venkitasamy, Lavine, Gary, Pandey, Rajendra K, Racie, Timothy, Rajeev, Kallanthottathil G, Röhl, Ingo, Toudjarska, Ivanka, Wang, Gang, Wuschko, Silvio, Bumcrot, David, Koteliansky, Victor, Limmer, Stefan, Manoharan, Muthiah, Vornlocher, Hans-Peter

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Integrated multi-stage LQR power oscillation damping FACTS controller von Pandey, Rajendra K., Gupta, Deepak Kumar

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Mechanism of action of hepatitis B virus S antigen transport-inhibiting oligonucleotide polymer, STOPS, molecules von Kao, C. Cheng, Nie, Yuchun, Ren, Suping, De Costa, N. Tilani T.S., Pandey, Rajendra K., Hong, Jin, Smith, David B., Symons, Julian A., Beigelman, Leonid, Blatt, Lawrence M.

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Targeting TLR9 agonists to secondary lymphoid organs induces potent immune responses against HBV infection von Ushach, Irina, Zhu, Ren, Rosler, Elen, Pandey, Rajendra K., De Costa, N. Tilani S., Pourshahian, Soheil, Han, Qinglin, Li, Chris, Beigelman, Leonid, Gryaznov, Sergei M., Yun, Theodore

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Durable protection from Herpes Simplex Virus-2 transmission following intravaginal application of siRNAs targeting both a viral and host gene von Wu, Yichao, Navarro, Francisco, Lal, Ashish, Basar, Emre, Pandey, Rajendra K, Manoharan, Muthiah, Feng, Yang, Lee, Sandra J, Lieberman, Judy, Palliser, Deborah

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In vivo silencing of alpha-synuclein using naked siRNA von Lewis, Jada, Melrose, Heather, Bumcrot, David, Hope, Andrew, Zehr, Cynthia, Lincoln, Sarah, Braithwaite, Adam, He, Zhen, Ogholikhan, Sina, Hinkle, Kelly, Kent, Caroline, Toudjarska, Ivanka, Charisse, Klaus, Braich, Ravi, Pandey, Rajendra K, Heckman, Michael, Maraganore, Demetrius M, Crook, Julia, Farrer, Matthew J

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Unique Gene-Silencing and Structural Properties of 2′-Fluoro-Modified siRNAs von Manoharan, Muthiah, Akinc, Akin, Pandey, Rajendra K, Qin, June, Hadwiger, Philipp, John, Matthias, Mills, Kathy, Charisse, Klaus, Maier, Martin A, Nechev, Lubomir, Greene, Emily M, Pallan, Pradeep S, Rozners, Eriks, Rajeev, Kallanthottathil G, Egli, Martin

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Knowledge domain states mapping concept for controller tuning in an interconnected power network von Pandey, Rajendra K., Gupta, Deepak Kumar

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New Oligonucleotide 2′-O-Alkyl N3′→P5′ (Thio)-Phosphoramidates as Potent Antisense Agents: Physicochemical Properties and Biological Activity von Martínez-Montero, Saúl, Rajwanshi, Vivek K., Pandey, Rajendra K., De Costa, N. Tilani S., Hong, Jin, Beigelman, Leonid, Gryaznov, Sergei M., Pourshahian, Soheil

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Mechanistic Insights into LDL Nanoparticle-Mediated siRNA Delivery von Jin, Honglin, Lovell, Jonathan F, Chen, Juan, Lin, Qiaoya, Ding, Lili, Ng, Kenneth K, Pandey, Rajendra K, Manoharan, Muthiah, Zhang, Zhihong, Zheng, Gang

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Secondary structures in CpG oligonucleotides affect immunostimulatory activity von Kandimalla, Ekambar R, Bhagat, Lakshmi, Cong, Yan-Ping, Pandey, Rajendra K, Yu, Dong, Zhao, Qiuyan, Agrawal, Sudhir

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Modulation of thermal stability can enhance the potency of siRNA von Addepalli, Haripriya, Meena, Peng, Chang G, Wang, Gang, Fan, Yupeng, Charisse, Klaus, Jayaprakash, K Narayanannair, Rajeev, Kallanthottathil G, Pandey, Rajendra K, Lavine, Gary, Zhang, Ligang, Jahn-Hofmann, Kerstin, Hadwiger, Philipp, Manoharan, Muthiah, Maier, Martin A

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Lipophilic siRNAs mediate efficient gene silencing in oligodendrocytes with direct CNS delivery von Chen, Qingmin, Butler, David, Querbes, William, Pandey, Rajendra K., Ge, Pei, Maier, Martin A., Zhang, Ligang, Rajeev, Kallanthottathil G., Nechev, Lubomir, Kotelianski, Victor, Manoharan, Muthiah, Sah, Dinah W.Y.

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Metabolism, pharmacokinetics, tissue distribution, and stability studies of the prodrug analog of an anti-hepatitis B virus dinucleoside phosphorothioate von Coughlin, John E, Pandey, Rajendra K, Padmanabhan, Seetharamaiyer, O'Loughlin, Kathleen G, Marquis, Judith, Green, Carol E, Mirsalis, Jon C, Iyer, Radhakrishnan P

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Self-stabilized CpG DNAs optimally activate human B cells and plasmacytoid dendritic cells von Cong, Yan-Ping, Song, Sam S, Bhagat, Lakshmi, Pandey, Rajendra K, Yu, Dong, Kandimalla, Ekambar R, Agrawal, Sudhir

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Hybridization-based fluorescence assay allows quantitation of single-stranded oligodeoxynucleotides in low nanomolar range von Kandimalla, Ekambar R., Pandey, Rajendra K., Agrawal, Sudhir

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Unexpected origins of the enhanced pairing affinity of 2;#8242;-fluoro-modified RNA von Pallan, Pradeep S., Greene, Emily M., Jicman, Paul Andrei, Pandey, Rajendra K., Manoharan, Muthiah, Rozners, Eriks, Egli, Martin

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