A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa von Lu, Genmin, DeGuzman, Francis R, Hollenbach, Stanley J, Karbarz, Mark J, Abe, Keith, Lee, Gail, Luan, Peng, Hutchaleelaha, Athiwat, Inagaki, Mayuko, Conley, Pamela B, Phillips, David R, Sinha, Uma

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Transient or extended reversal of apixaban anticoagulation by andexanet alfa is equally effective in a porcine polytrauma model von Grottke, Oliver, Braunschweig, Till, Rossaint, Rolf, Akman, Necib, Leeds, Janet M., Conley, Pamela B., Honickel, Markus

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Effects of ibrutinib treatment on murine platelet function during inflammation and in primary hemostasis von Lee, Robert H, Piatt, Raymond, Conley, Pamela B, Bergmeier, Wolfgang

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Autocrine purinergic receptor signaling is essential for macrophage chemotaxis von Kronlage, Moritz, Song, Jian, Sorokin, Lydia, Isfort, Katrin, Schwerdtle, Tanja, Leipziger, Jens, Robaye, Bernard, Conley, Pamela B, Kim, Hee-Cheol, Sargin, Sarah, Schön, Peter, Schwab, Albrecht, Hanley, Peter J

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Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model von Lu, Genmin, Pine, Polly, Leeds, Janet M, DeGuzman, Francis, Pratikhya, Pratikhya, Lin, Joyce, Malinowski, John, Hollenbach, Stanley J, Curnutte, John T, Conley, Pamela B

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The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia von Blunt, Matthew D, Koehrer, Stefan, Dobson, Rachel C, Larrayoz, Marta, Wilmore, Sarah, Hayman, Alice, Parnell, Jack, Smith, Lindsay D, Davies, Andrew, Johnson, Peter W M, Conley, Pamela B, Pandey, Anjali, Strefford, Jonathan C, Stevenson, Freda K, Packham, Graham, Forconi, Francesco, Coffey, Greg P, Burger, Jan A, Steele, Andrew J

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Role of the P2Y12 receptor in the modulation of murine dendritic cell function by ADP von Ben Addi, Abduelhakem, Cammarata, Dorothée, Conley, Pamela B, Boeynaems, Jean-Marie, Robaye, Bernard

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Identification of the platelet ADP receptor targeted by antithrombotic drugs von Conley, Pamela B, Hollopeter, Gunther, Jantzen, Hans-Michael, Vincent, Diana, Li, Georgia, England, Laura, Ramakrishnan, Vanitha, Yang, Ruey-Bing, Nurden, Paquita, Nurden, Alan, Julius, David

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The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling von Su, Xinming, Floyd, Desiree H, Hughes, Alun, Xiang, Jingyu, Schneider, Jochen G, Uluckan, Ozge, Heller, Emanuela, Deng, Hongju, Zou, Wei, Craft, Clarissa S, Wu, Kaiming, Hirbe, Angela C, Grabowska, Dorota, Eagleton, Mark C, Townsley, Sarah, Collins, Lynne, Piwnica-Worms, David, Steinberg, Thomas H, Novack, Deborah V, Conley, Pamela B, Hurchla, Michelle A, Rogers, Michael, Weilbaecher, Katherine N

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Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors von Kalathottukaren, Manu T., Creagh, A. Louise, Abbina, Srinivas, Lu, Genmin, Karbarz, Mark J., Pandey, Anjali, Conley, Pamela B., Kizhakkedathu, Jayachandran N., Haynes, Charles

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Cutting edge: Leukotriene C4 activates mouse platelets in plasma exclusively through the type 2 cysteinyl leukotriene receptor von Cummings, Hannah E, Liu, Tao, Feng, Chunli, Laidlaw, Tanya M, Conley, Pamela B, Kanaoka, Yoshihide, Boyce, Joshua A

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P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries von Andre, Patrick, Delaney, Suzanne M, LaRocca, Thomas, Vincent, Diana, DeGuzman, Francis, Jurek, Marzena, Koller, Beverley, Phillips, David R, Conley, Pamela B

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Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity von Siegal, Deborah M, Curnutte, John T, Connolly, Stuart J, Lu, Genmin, Conley, Pamela B, Wiens, Brian L, Mathur, Vandana S, Castillo, Janice, Bronson, Michele D, Leeds, Janet M, Mar, Florie A, Gold, Alex, Crowther, Mark A

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Safety, pharmacokinetics, and reversal of apixaban anticoagulation with andexanet alfa von Siegal, Deborah, Lu, Genmin, Leeds, Janet M., Karbarz, Mark, Castillo, Janice, Mathur, Vandana, Hutchaleelaha, Athiwat, Sinha, Uma, Kitt, Michael, McClure, Matt, Hollenbach, Stanley J., Curnutte, John T., Conley, Pamela B., Crowther, Mark

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P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms von Hardy, Adam R., Conley, Pamela B., Luo, Jiansong, Benovic, Jeffrey L., Poole, Alastair W., Mundell, Stuart J.

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Platelet Endothelial Aggregation Receptor 1 (PEAR1), a Novel Epidermal Growth Factor Repeat-containing Transmembrane Receptor, Participates in Platelet Contact-induced Activation von Nanda, Nisha, Bao, Ming, Lin, Hanna, Clauser, Karl, Komuves, Laszlo, Quertermous, Thomas, Conley, Pamela B., Phillips, David R., Hart, Matthew J.

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Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding von Cattaneo, Marco, Zighetti, Maddalena L, Lombardi, Rossana, Martinez, Constantino, Lecchi, Anna, Conley, Pamela B, Ware, Jerry, Ruggeri, Zaverio M

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Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors von Connolly, Stuart J, Milling, Truman J, Eikelboom, John W, Gibson, C. Michael, Curnutte, John T, Gold, Alex, Bronson, Michele D, Lu, Genmin, Conley, Pamela B, Verhamme, Peter, Schmidt, Jeannot, Middeldorp, Saskia, Cohen, Alexander T, Beyer-Westendorf, Jan, Albaladejo, Pierre, Lopez-Sendon, Jose, Goodman, Shelly, Leeds, Janet, Wiens, Brian L, Siegal, Deborah M, Zotova, Elena, Meeks, Brandi, Nakamya, Juliet, Lim, W. Ting, Crowther, Mark

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Hemostatic Efficacy and Anti-FXa (Factor Xa) Reversal With Andexanet Alfa in Intracranial Hemorrhage: ANNEXA-4 Substudy von Demchuk, Andrew M., Yue, Patrick, Zotova, Elena, Nakamya, Juliet, Xu, Lizhen, Milling, Truman J., Ohara, Tomoyuki, Goldstein, Joshua N., Middeldorp, Saskia, Verhamme, Peter, Lopez-Sendon, Jose Luis, Conley, Pamela B., Curnutte, John T., Eikelboom, John W., Crowther, Mark, Connolly, Stuart J.

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Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling von Nanda, Nisha, Andre, Patrick, Bao, Ming, Clauser, Karl, Deguzman, Francis, Howie, Duncan, Conley, Pamela B., Terhorst, Cox, Phillips, David R.

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