In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B von TOWLE, Murray J, SALVATO, Kathleen A, HABGOOD, Gregory J, SINGER, Lori A, DIPIETRO, Lucian V, YUAN WANG, CHEN, Jack J, QUINCY, David A, DAVIS, Ashley, YOSHIMATSU, Kentaro, KISHI, Yoshito, YU, Melvin J, BUDROW, Jacqueline, LITTLEFIELD, Bruce A, WELS, Bruce F, KUZNETSOV, Galina, AALFS, Kimberley K, WELSH, Susan, WANJUN ZHENG, SELETSKY, Boris M, PALME, Monica H

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Macrocyclic ketone analogues of halichondrin B von Zheng, Wanjun, Seletsky, Boris M., Palme, Monica H., Lydon, Paul J., Singer, Lori A., Chase, Charles E., Lemelin, Charles A., Shen, Yongchun, Davis, Heather, Tremblay, Lynda, Towle, Murray J., Salvato, Kathleen A., Wels, Bruce F., Aalfs, Kimberley K., Kishi, Yoshito, Littlefield, Bruce A., Yu, Melvin J.

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Structurally simplified macrolactone analogues of halichondrin B von Seletsky, Boris M., Wang, Yuan, Hawkins, Lynn D., Palme, Monica H., Habgood, Gregory J., DiPietro, Lucian V., Towle, Murray J., Salvato, Kathleen A., Wels, Bruce F., Aalfs, Kimberley K., Kishi, Yoshito, Littlefield, Bruce A., Yu, Melvin J.

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MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 4: Addressing the problem of poor stability due to photoisomerization of an acrylic acid moiety von Nakayama, Kiyoshi, Kuru, Noriko, Ohtsuka, Masami, Yokomizo, Yoshihiro, Sakamoto, Atsunobu, Kawato, Haruko, Yoshida, Ken-ichi, Ohta, Toshiharu, Hoshino, Kazuki, Akimoto, Katsuya, Itoh, Junko, Ishida, Hiroko, Cho, Aesop, Palme, Monica H., Zhang, Jason Z., Lee, Ving J., Watkins, William J.

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MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 3: Optimization of potency in the pyridopyrimidine series through the application of a pharmacophore mode... von Nakayama, Kiyoshi, Kawato, Haruko, Watanabe, Jun, Ohtsuka, Masami, Yoshida, Ken-ichi, Yokomizo, Yoshihiro, Sakamoto, Atsunobu, Kuru, Noriko, Ohta, Toshiharu, Hoshino, Kazuki, Yoshida, Kumi, Ishida, Hiroko, Cho, Aesop, Palme, Monica H., Zhang, Jason Z., Lee, Ving J., Watkins, William J.

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Tecarfarin: A Novel Oral Anticoagulant and Characterization of it Pharmacokinetics, Tissue Distribution, and Mass Balance in Sprague‐Dawley Rats von Rao, Satish, Shao, Lei, Irwin, Ian, Palme, Monica, Druzgala, Pascal

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Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders von BOWERSOX, S. Scott, LIGHTNING, Luke K, RAO, Satish, PALME, Monica, ELLIS, Dave, COLEMAN, Renee, DAVIES, Adrian M, KUMARASWAMY, Padmapriya, DRUZGALA, Pascal

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A Phase II, Randomized, Double-Blind, Placebo Controlled, Three Period, Crossover, Single Center Study to Evaluate the Effects of Naronapride on Esophageal and Gastric pH and Reflu... von Ellis, Dave J, Palme, Monica, Miner, Philip B

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The Pharmacokinetics and Tolerability of Naronapride, a 5-HT4 Receptor Agonist, in Healthy Subjects von Ellis, Dave J, Bowersox, Scott, Palme, Monica, Druzgala, Pascal

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Tecarfarin: A New Oral Anticoagulant and the Characterization of its In Vitro Metabolism Using Rat, Dog, and Human Hepatocytes von Lightning, Luke, Kumaraswamy, Padmapriya, Coleman, Renee, Irwin, Ian, Palme, Monica, Druzgala, Pascal

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Molecular Pharmacology of Naronapride, a Selective 5-HT4 Receptor Agonist for the Treatment of Constipation: Comparison With Other Prokinetic 5-HT4 Receptor Agonists von Bowersox, S.S, Clark, Richard, Ellis, Dave J, Palme, Monica, Sims, E, Druzgala, Pascal

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S1033 Results of a Thorough QT Study (ICH E14) Testing a Novel Gastrointestinal Prokinetic, ATI-7505, Show NO ECG Effects at Therapeutic and Supra-Therapeutic Doses von Milner, Peter G, Canafax, Daniel M, Palme, Monica, Morganroth, Joel

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Synthesis and reactivity of a new glycosyl donor: O-(1-phenyltetrazol-5-yl) glucoside von Palme, Monica, Vasella, Andrea

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Pharmacological characteristics of ATI‐9242, a Novel Atypical Antipsychotic von Choppin, Agnes, Lach, Leang, Lee, Alexander, Nunez, Oscar, Becker, Cyrus, Palme, Monica P, Paliard, Xavier, Druzgala, Pascal, Jasper, Jeffrey R

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Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT 4 Receptor Agonist for Gastrointestinal Motility Disorders von Bowersox, S. Scott, Lightning, Luke K., Rao, Satish, Palme, Monica, Ellis, Dave, Coleman, Renee, Davies, Adrian M., Kumaraswamy, Padmapriya, Druzgala, Pascal

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158 Efficacy of ATI-7505, a Novel Highly Selective 5-HT 4 Receptor Agonist, in a Rodent Model of Colonic Hypersensitivity von Johnson, Anthony C., Tyler, Karl R., Palme, Monica, Meerveld, Beverley Greenwood-Van

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158 Efficacy of ATI-7505, a Novel Highly Selective 5-HT4 Receptor Agonist, in a Rodent Model of Colonic Hypersensitivity von Johnson, Anthony C, Tyler, Karl R, Palme, Monica, Meerveld, Beverley Greenwood-Van

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905 A Novel Gastrointestinal Prokinetic, ATI-7505, Increased Spontaneous Bowel Movements (Sbms) in a Phase II, Randomized, Placebo-Controlled Study of Patients With Chronic Idiopat... von Palme, Monica, Milner, Peter G, Ellis, Dave J, Marmon, Tonya, Canafax, Daniel M

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Lack of Drug‐Drug Interaction Between ATI‐5923, a Novel Vitamin K Epoxide Reductase Inhibitor, and Amiodarone, in Beagle Dog von Choppin, Agnes, Irwin, Ian, Lach, Lach, Davies, Adrian, Shao, Lei, Becker, Cyrus, Palme, Monica P, Paliard, Xavier, Bowersox, Scott, Dennis, Donn M, Druzgala, Pascal

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Lack of Drug-Drug Interaction Between ATI-5923, a Novel Vitamin K Epoxide Reductase Inhibitor, and Amiodarone, in Beagle Dog von Choppin, Anges, Irwin, Ian, Lach, Leang, Davies, Adrian, Shao, Lei, Becker, Cyrus, Palme, Monica P., Paliard, Xavier, Bowersox, Scott, Dennis, Donn, Druzgala, Paliard

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