AVEREL: A Randomized Phase III Trial Evaluating Bevacizumab in Combination With Docetaxel and Trastuzumab As First-Line Therapy for HER2-Positive Locally Recurrent/Metastatic Breas... von GIANNI, Luca, ROMIEU, Gilles H, CHAN, Stephen, WARDLEY, Andrew, GREIL, Richard, MOORE, Nicola, PROT, Sylvie, PALLAUD, Celine, SEMIGLAZOV, Vladimir, LICHINITSER, Michail, SERRANO, Sergio V, MANSUTTI, Mauro, PIVOT, Xavier, MARIANI, Paola, ANDRE, Fabrice, CHAN, Arlene, LIPATOV, Oleg

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Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial von Migden, Michael R, Dr, Guminski, Alexander, PhD, Gutzmer, Ralf, Prof, Dirix, Luc, MD, Lewis, Karl D, MD, Combemale, Patrick, MD, Herd, Robert M, MD, Kudchadkar, Ragini, MD, Trefzer, Uwe, Prof, Gogov, Sven, MD, Pallaud, Celine, PhD, Yi, Tingting, PhD, Mone, Manisha, PhD, Kaatz, Martin, MD, Loquai, Carmen, MD, Stratigos, Alexander J, Prof, Schulze, Hans-Joachim, MD, Plummer, Ruth, Prof, Chang, Anne Lynn S, MD, Cornélis, Frank, MD, Lear, John T, MD, Sellami, Dalila, MD, Dummer, Reinhard, Prof

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Panobinostat induces CD38 upregulation and augments the antimyeloma efficacy of daratumumab von García-Guerrero, Estefanía, Gogishvili, Tea, Danhof, Sophia, Schreder, Martin, Pallaud, Celine, Pérez-Simón, Jose Antonio, Einsele, Hermann, Hudecek, Michael

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Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results von Rücker, Frank G., Du, Ling, Luck, Tamara J., Benner, Axel, Krzykalla, Julia, Gathmann, Insa, Voso, Maria Teresa, Amadori, Sergio, Prior, Thomas W., Brandwein, Joseph M., Appelbaum, Frederick R., Medeiros, Bruno C., Tallman, Martin S., Savoie, Lynn, Sierra, Jorge, Pallaud, Celine, Sanz, Miguel A., Jansen, Joop H., Niederwieser, Dietger, Fischer, Thomas, Ehninger, Gerhard, Heuser, Michael, Ganser, Arnold, Bullinger, Lars, Larson, Richard A., Bloomfield, Clara D., Stone, Richard M., Döhner, Hartmut, Thiede, Christian, Döhner, Konstanze

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Adjuvant bevacizumab-containing therapy in triple-negative breast cancer (BEATRICE): primary results of a randomised, phase 3 trial von Cameron, David, Prof, Brown, Julia, Prof, Dent, Rebecca, MD, Jackisch, Christian, MD, Mackey, John, Prof, Pivot, Xavier, MD, Steger, Guenther G, Prof, Suter, Thomas M, Prof, Toi, Masakazu, Prof, Parmar, Mahesh, DPhil, Laeufle, Rita, MD, Im, Young-Hyuck, MD, Romieu, Gilles, MD, Harvey, Vernon, MD, Lipatov, Oleg, MD, Pienkowski, Tadeusz, MD, Cottu, Paul, MD, Chan, Arlene, Prof, Im, Seock-Ah, Prof, Hall, Peter S, PhD, Bubuteishvili-Pacaud, Lida, MD, Henschel, Volkmar, PhD, Deurloo, Regula J, PhD, Pallaud, Celine, PhD, Bell, Richard, Prof

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The 12-month analysis from Basal Cell Carcinoma Outcomes with LDE225 Treatment (BOLT): A phase II, randomized, double-blind study of sonidegib in patients with advanced basal cell... von Dummer, Reinhard, MD, Guminski, Alexander, MD, PhD, Gutzmer, Ralf, MD, Dirix, Luc, MD, Lewis, Karl D., MD, Combemale, Patrick, MD, Herd, Robert M., MD, Kaatz, Martin, MD, Loquai, Carmen, MD, Stratigos, Alexander J., MD, Schulze, Hans-Joachim, MD, Plummer, Ruth, MD, Gogov, Sven, MD, Pallaud, Celine, PhD, Yi, Tingting, PhD, Mone, Manisha, PhD, Chang, Anne Lynn S., MD, Cornélis, Frank, MD, Kudchadkar, Ragini, MD, Trefzer, Uwe, MD, Lear, John T., MD, Sellami, Dalila, MD, Migden, Michael R., MD

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Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1 von Tausch, Eugen, Beck, Philipp, Schlenk, Richard F, Jebaraj, Billy J, Dolnik, Anna, Yosifov, Deyan Y, Hillmen, Peter, Offner, Fritz, Janssens, Ann, Babu, K Govind, Grosicki, Sebastian, Mayer, Jiri, Panagiotidis, Panagiotis, McKeown, Astrid, Gupta, Ira V, Skorupa, Alexandra, Pallaud, Celine, Bullinger, Lars, Mertens, Daniel, Döhner, Hartmut, Stilgenbauer, Stephan

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Next‐generation sequencing of baseline genetic mutations and outcomes of eltrombopag and azacitidine therapy in patients with myelodysplastic syndromes and thrombocytopenia: Data f... von Ramos, Pedro Marques, Choi, Jeea, Campbell, Catarina D., Wang, Ying A., Pallaud, Celine, Dickinson, Michael, Verma, Amit, Mittelman, Moshe, Platzbecker, Uwe, Cherif, Honar, Fenaux, Pierre

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Biomarker (BM) evaluations in the phase III AVAglio study of bevacizumab (Bv) plus standard radiotherapy (RT) and temozolomide (T) for newly diagnosed glioblastoma (GBM) von Nishikawa, Ryo, Saran, Frank, Mason, Warren, Wick, Wolfgang, Cloughesy, Timothy Francis, Henriksson, Roger, Hilton, Magalie, Garcia, Josep, Vogt, Tobias, Pallaud, Celine, Chinot, Oliver L.

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Impact of NPM1/FLT3-ITD genotypes defined by the 2017 European LeukemiaNet in patients with acute myeloid leukemia von Döhner, Konstanze, Thiede, Christian, Jahn, Nikolaus, Panina, Ekaterina, Gambietz, Agnes, Larson, Richard A., Prior, Thomas W., Marcucci, Guido, Jones, Dan, Krauter, Jürgen, Heuser, Michael, Voso, Maria Teresa, Ottone, Tiziana, Nomdedeu, Josep F., Mandrekar, Sumithra J., Klisovic, Rebecca B., Wei, Andrew H., Sierra, Jorge, Sanz, Miguel A., Brandwein, Joseph M., de Witte, Theo, Jansen, Joop H., Niederwieser, Dietger, Appelbaum, Frederick R., Medeiros, Bruno C., Tallman, Martin S., Schlenk, Richard F., Ganser, Arnold, Serve, Hubert, Ehninger, Gerhard, Amadori, Sergio, Gathmann, Insa, Benner, Axel, Pallaud, Celine, Stone, Richard M., Döhner, Hartmut, Bloomfield, Clara D.

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Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial von Jahn, Nikolaus, Jahn, Ekaterina, Saadati, Maral, Bullinger, Lars, Larson, Richard A., Ottone, Tiziana, Amadori, Sergio, Prior, Thomas W., Brandwein, Joseph M., Appelbaum, Frederick R., Medeiros, Bruno C., Tallman, Martin S., Ehninger, Gerhard, Heuser, Michael, Ganser, Arnold, Pallaud, Celine, Gathmann, Insa, Krzykalla, Julia, Benner, Axel, Bloomfield, Clara D., Thiede, Christian, Stone, Richard M., Döhner, Hartmut, Döhner, Konstanze

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Exploring the Clinical Utility of Renal Safety Biomarkers during Iron Chelation Therapy in Patients with β-Thalassemia and Other Anemias von Cappellini, Maria Domenica, Quebe-Fehling, Erhard, Pallaud, Celine, Dieterle, Frank, Porter, John B.

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Megakaryopoiesis impairment through acute innate immune signaling activation by azacitidine von Okoye-Okafor, Ujunwa Cynthia, Javarappa, Komal K, Tsallos, Dimitrios, Saad, Joseph, Yang, Daozheng, Zhang, Chi, Benard, Lumie, Thiruthuvanathan, Victor J, Cole, Sally, Ruiz, Stephen, Tatiparthy, Madhuri, Choudhary, Gaurav, DeFronzo, Stefanie, Bartholdy, Boris A, Pallaud, Celine, Ramos, Pedro Marques, Shastri, Aditi, Verma, Amit, Heckman, Caroline A, Will, Britta

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Eltrombopag Promotes Megakaryocyte Survival and Signaling in the Presence of Specific Cytotoxic Agents von Javarappa, Komal Kumar, Tsallos, Dimitrios, Zagidullin, Bulat, Saad, Joseph J, Tang, Jing, Marques Ramos, Pedro, Pallaud, Celine, Heckman, Caroline A

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A Correlative Biomarker Analysis of the Combination of Bevacizumab and Carboplatin-Based Chemotherapy for Advanced Nonsquamous Non–Small-Cell Lung Cancer: Results of the Phase II R... von Mok, Tony, Gorbunova, Vera, Juhasz, Erzsebet, Szima, Barna, Burdaeva, Olga, Orlov, Sergey, Yu, Chong-Jen, Archer, Venice, Hilton, Magalie, Delmar, Paul, Pallaud, Celine, Reck, Martin

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Pre-Clinical Modeling of Concomitant Therapy with Azacytidine and Eltrombopag in MDS/AML von Cole, Sally, Benard, Lumie, Carvajal, Luis A., Verma, Amit, Steidl, Ulrich G., Marques Ramos, Pedro, Pallaud, Celine, Will, Britta

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Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival von Brück, Oscar, Dufva, Olli, Hohtari, Helena, Blom, Sami, Turkki, Riku, Ilander, Mette, Kovanen, Panu, Pallaud, Celine, Ramos, Pedro Marques, Lähteenmäki, Hanna, Välimäki, Katja, El Missiry, Mohamed, Ribeiro, Antonio, Kallioniemi, Olli, Porkka, Kimmo, Pellinen, Teijo, Mustjoki, Satu

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Expanding the Utility of Midostaurin in Acute Myeloid Leukemia - Predictive Mutational Signatures in Patient Samples without FLT3 mutations and Clinically Applicable Synergistic Dr... von Vaha-Koskela, Markus, Ammad-ud-din, Muhammad, Siivola, Kirsi, Ruokoranta, Tanja, Turunen, Laura, Porkka, Kimmo, Marques Ramos, Pedro, Pallaud, Celine, Aittokallio, Tero, Wennerberg, Krister

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Azacytidine Inhibits Megakaryopoiesis Via the Induction of Immunogenic RNA Species and Activation of Type-I Interferon Signaling von Okoye-Okafor, Ujunwa Cynthia, Javarappa, Komal Kumar, Tsallos, Dimitrios, Saad, Joseph J, Benard, Lumie, Thiruthuvanathan, Victor, Cole, Sally, Tatiparthy, Madhuri, Ruiz, Stephen, DeFronzo, Stefanie, Pallaud, Celine, Marques Ramos, Pedro, Verma, Amit, Shastri, Aditi, Heckman, Caroline A, Will, Britta

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3025 – AZACITIDINE INDUCES THROMBOCYTOPENIA VIA INHIBITION OF MEGAKARYOPOIESIS von Okoye-Okafor, Ujunwa, Javarappa, Komal, Tsallos, Dimitrios, Saad, Joseph, Benard, Lumie, Thiruthuvanathan, Victor, Cole, Sally, Ruiz, Stephen, Tatiparthy, Madhuri, Choudhary, Gaurav, DeFronzo, Stefanie, Bartholdy, Boris, Pallaud, Celine, Ramos, Pedro, Shastri, Aditi, Verma, Amit, Heckman, Caroline, Will, Britta

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