Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for the treatment of cancer von Xiang, Hong, Chan, Abigael G, Ahene, Ago, Bellovin, David I, Deng, Rong, Hsu, Amy W, Jeffry, Ursula, Palencia, Servando, Powers, Janine, Zanghi, James, Collins, Helen

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R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/β-catenin pathway von Zhao, Jingsong, Kim, Kyung-Ah, De Vera, Josephine, Palencia, Servando, Wagle, Marie, Abo, Arie

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rNAPc2 Inhibits Colorectal Cancer in Mice through Tissue Factor von Zhao, Jingsong, Aguilar, Gerard, Palencia, Servando, Newton, Elizabeth, Abo, Arie

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Mouse R-spondin2 is required for apical ectodermal ridge maintenance in the hindlimb von Nam, Ju-Suk, Park, Emily, Turcotte, Taryn J., Palencia, Servando, Zhan, Xiaoming, Lee, Jackie, Yun, Kyuson, Funk, Walter D., Yoon, Jeong Kyo

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High Dimensional Profiling of Patient-Derived Multiple Myeloma Bone Marrow Specimens Treated with an FcRH5-Targeted Bispecific Ex Vivo von Roy, Sumi, Del Cid, Adriana, Lu, Kai, Diaz, Giovanni, Ulukaya, Gulay Bengu, Palencia, Servando, Nakamura, Rin, Bolen, Christopher R., Hatzi, Katerina

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Abstract 1407: FPA144, a therapeutic monoclonal antibody targeting the FGFR2b receptor, promotes antibody dependent cell-mediated cytotoxicity and stimulates sensitivity to PD-1 in... von Powers, Janine, Palencia, Servando, Foy, Susan, Sennino, Barbara, Hidalgo, Toni Rose, Gemo, Abigael, Brennan, Thomas, Pierce, Kisten

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Abstract 5449: FP-1039/GSK3052230, an FGF ligand trap, enhances VEGF antagonist therapy in preclinical models of RCC and HCC von Bellovin, David I., Palencia, Servando, Hestir, Kevin, Lee, Ernestine, DeYoung, M. Phillip, Brennan, Thomas, Los, Gerrit, Baker, Kevin

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Abstract 2845: Expression of FGFR2b in gastric cancer as measured by immunohistochemistry with a highly specific monoclonal antibody von Deshpande, Amit M., Palencia, Servando, Bellovin, David I., Gemo, Abigael T., Giese, Tina, Stohr, Bradley, Pierce, Kristen L., Los, Gerrit

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R-spondin1, A Novel Intestinotrophic Mitogen, Ameliorates Experimental Colitis in Mice von Zhao, Jingsong, de Vera, Josephine, Narushima, Seiko, Beck, Eric X, Palencia, Servando, Shinkawa, Pauline, Kim, Kyung–Ah, Liu, Yi, Levy, Michael D, Berg, Daniel J, Abo, Arie, Funk, Walter D

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Abstract 5446: FPA144: A therapeutic antibody for treating patients with gastric cancers bearing FGFR2 gene amplification von Gemo, Abigael T., Deshpande, Amit M., Palencia, Servando, Bellovin, David I., Brennan, Thomas J., Patil, Namrata S., Huang, Carol, Los, Gerrit, Pierce, Kristen L.

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FPA144, a humanized monoclonal antibody for both FGFR2 -amplified and nonamplified, FGFR2b -overexpressing gastric cancer patients von Pierce, Kristen L., Deshpande, Amit M., Stohr, Bradley A., Gemo, Abigael T., Patil, Namrata S., Brennan, Thomas J., Bellovin, David I., Palencia, Servando, Giese, Tina, Huang, Carol, Baker, Kevin P., Kavanaugh, W. Michael, Hambleton, Julie, Los, Gerrit

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Identification of novel immune regulators of tumor growth using RIPPS screening in vivo von Brennan, Tom, Bellovin, David, de la Torre, Jacqueline, Wondyfraw, Nebiyu, Palencia, Servando, Hestir, Kevin, Lee, Ernestine

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Abstract 1876: Preclinical efficacy of fibroblast growth factor ligand trap HGS1036 in lung carcinoma models with genomic amplification of FGFR1 von Harding, Thomas, Palencia, Servando, Wallace, Tiffany, Levin, Anita, Patil, Namrata, Cheung, Ruby, Aguirre, Mallory, Long, Li, Humphreys, Robin, Kavanaugh, Mike, Baker, Kevin

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The complete complement of C1q-domain-containing proteins in Homo sapiens von Tom Tang, Y., Hu, Tianhua, Arterburn, Matthew, Boyle, Bryan, Bright, Jessica M., Palencia, Servando, Emtage, Peter C., Funk, Walter D.

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Abstract 2597: Preclinical efficacy of FP-1039 (FGFR1: Fc) in endometrial carcinoma models with activating mutations in FGFR2 von Harding, Thomas C., Palencia, Servando, Long, Li, Finer, Jeff, Keer, Harold N., Baker, Kevin P., Kavanaugh, Michael

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R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/[beta]-catenin pathway von Zhao, Jingsong, Kim, Kyung-Ah, De Vera, Josephine, Palencia, Servando, Wagle, Marie, Abo, Arie

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R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/β-catenin pathway von Zhao, Jingsong, Kim, Kyung-Ah, De Vera, Josephine, Palencia, Servando, Wagle, Marie, Abo, Arie

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Identification of a novel immune checkpoint regulator and potential therapeutic antibody target in oncology von Sallee, Nathan, Karasyov, Artur, Bellovin, David, Liang, Ryan, de la Torre, Jacqueline, Palencia, Servando, Lee, Ernestine, Hestir, Kevin, Brennan, Thomas, Borges, Luis, Brace, Arthur, Wong, Brian

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The lymphoid cell surface receptor NTB‐A: a novel monoclonal antibody target for leukaemia and lymphoma therapeutics von Korver, Wouter, Singh, Shweta, Liu, Shouchun, Zhao, Xiaoxian, Yonkovich, Shirlee, Sweeney, Allison, Anton, Kristin, Lomas, Woodrow E., Greenwood, Rachel, Smith, Ashley, Tran, Denise Hoang, Shinkawa, Pauline, Jimenez, Mark, Yeung, Patricia, Aguilar, Gerard, Palencia, Servando, Vatta, Paolo, Mueller, Matthew, Zhan, Xiaoming, Newton, Elizabeth M., Liu, Yi, Zhao, Jingsong, Emtage, Peter, Levy, Michael D., Hsi, Eric D., Funk, Walter D., Abo, Arie

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FGFR2 inhibitors alone or in combination with immune stimulating agents in cancer treatment von Kartik Krishnan, Janine Powers, Kristen Pierce, Majid Ghoddusi, Robert Sikorski, Servando Palencia

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