Development of novel linkers to conjugate pharmacophores to a carrier antibody von Palanki, Moorthy S.S., Bhat, Abhijit, Lappe, Rodney W., Liu, Bin, Oates, Bryan, Rizzo, John, Stankovic, Nebojsa, Bradshaw, Curt

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Development of a long acting human growth hormone analog suitable for once a week dosing von Palanki, Moorthy S.S., Bhat, Abhijit, Bolanos, Ben, Brunel, Florence, Del Rosario, Joselyn, Dettling, Danielle, Horn, Mark, Lappe, Rodney, Preston, Ryan, Sievers, Annette, Stankovic, Nebojsa, Woodnut, Gary, Chen, Gang

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Discovery and preliminary structure–activity relationship studies of novel benzotriazine based compounds as Src inhibitors von Noronha, Glenn, Barrett, Kathy, Cao, Jianguo, Dneprovskaia, Elena, Fine, Richard, Gong, Xianchang, Gritzen, Colleen, Hood, John, Kang, Xinshan, Klebansky, Boris, Li, G., Liao, W., Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Soll, Richard, Splittgerber, Ute, Wrasidlo, Wolfgang, Zeng, Binqi, Zhao, Ningning, Zhou, Y.

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Special issue of Medicinal Chemistry Research in honor of Professor Gary L. Grunewald von Palanki, Moorthy S. S., Wolfe, Michael S., Hu, Longqin

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Discovery of 3,3‘-(2,4-Diaminopteridine-6,7-diyl)diphenol as an Isozyme-Selective Inhibitor of PI3K for the Treatment of Ischemia Reperfusion Injury Associated with Myocardial Infa... von Palanki, Moorthy S. S, Dneprovskaia, Elena, Doukas, John, Fine, Richard M, Hood, John, Kang, Xinshan, Lohse, Dan, Martin, Michael, Noronha, Glenn, Soll, Richard M, Wrasidlo, Wolfgang, Yee, Shiyin, Zhu, Hong

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Development of Prodrug 4-Chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl Benzoate (TG100801): A Topically Administered Therapeutic Ca... von Palanki, Moorthy S. S, Akiyama, Hideo, Campochiaro, Peter, Cao, Jianguo, Chow, Chun P, Dellamary, Luis, Doukas, John, Fine, Richard, Gritzen, Colleen, Hood, John D, Hu, Steven, Kachi, Shu, Kang, Xinshan, Klebansky, Boris, Kousba, Ahmed, Lohse, Dan, Mak, Chi Ching, Martin, Michael, McPherson, Andrew, Pathak, Ved P, Renick, Joel, Soll, Richard, Umeda, Naoyasu, Yee, Shiyin, Yokoi, Katsutoshi, Zeng, Binqi, Zhu, Hong, Noronha, Glenn

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Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activi... von Noronha, Glenn, Barrett, Kathy, Boccia, Antonio, Brodhag, Tessa, Cao, Jianguo, Chow, Chun P., Dneprovskaia, Elena, Doukas, John, Fine, Richard, Gong, Xianchang, Gritzen, Colleen, Gu, Hong, Hanna, Ehab, Hood, John D., Hu, Steven, Kang, Xinshan, Key, Jann, Klebansky, Boris, Kousba, Ahmed, Li, Ge, Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Shi, Feng, Soll, Richard, Splittgerber, Ute, Stoughton, Silva, Tang, Suhan, Yee, Shiyin, Zeng, Binqi, Zhao, Ningning, Zhu, Hong

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Inhibition of Nuclear Factor-κB in T Cells Suppresses Lung Fibrosis von FUJIMOTO, Hajime, D'ALESSANDRO-GABAZZA, Corina N, SUMIDA, Yasuhiro, ADACHI, Yukihiko, SUZUKI, Koji, TAGUCHI, Osamu, PALANKI, Moorthy S. S, ERDMAN, Paul E, TAKAGI, Takehiro, GABAZZA, Esteban C, BRUNO, Nelson E, YANO, Yutaka, HAYASHI, Tatsuya, TAMAKI, Shigenori

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The design and preliminary structure–activity relationship studies of benzotriazines as potent inhibitors of Abl and Abl-T315I enzymes von Cao, Jianguo, Fine, Richard, Gritzen, Colleen, Hood, John, Kang, Xinshan, Klebansky, Boris, Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Noronha, Glenn, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Soll, Richard, Zeng, Binqi, Zhu, Hong

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Development of novel benzotriazines for drug discovery von Palanki, Moorthy SS, Cao, Jianguo, Chow, Chun P, Dneprovskaia, Elena, Mak, Chi Ching, McPherson, Andrew, Pathak, Ved P, Renick, Joel, Soll, Richard, Zeng, Binqi, Noronha, Glenn

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The design and synthesis of novel orally active inhibitors of AP-1 and NF-κB mediated transcriptional activation. SAR of In vitro and In vivo studies von Palanki, Moorthy S.S., Erdman, Paul E., Ren, Minghuan, Suto, Mark, Bennett, Brydon L., Manning, Anthony, Ransone, Lynn, Spooner, Cheryl, Desai, Sonal, Ow, Arnie, Totsuka, Ryuichi, Tsao, Peter, Toriumi, Wataru

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Structure–Activity Relationship Studies of Ethyl 2-[(3-Methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate: An Inhibitor of AP-1 and NF-κB Mediated Ge... von Palanki, Moorthy S.S., Gayo-Fung, Leah M., Shevlin, Graziella I., Erdman, Paul, Sato, Mark, Goldman, Mark, Ransone, Lynn J., Spooner, Cheryl

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Solution-phase parallel synthesis using ion-exchange resins von Suto, Mark J., Gayo-Fung, Leah M., Palanki, Moorthy S.S., Sullivan, Robert

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2-Chloro-4-(trifluoromethyl)pyrimidine-5-N-(3‘,5‘-bis(trifluoromethyl)phenyl)- carboxamide:  A Potent Inhibitor of NF-κB- and AP-1-Mediated Gene Expression Identified Using Solutio... von Sullivan, Robert W, Bigam, Colin G, Erdman, Paul E, Palanki, Moorthy S. S, Anderson, David W, Goldman, Mark E, Ransone, Lynn J, Suto, Mark J

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Functional analogs of CC-1065 and the duocarmycins incorporating the 9a-(chloromethyl)-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (C2BI) alkylation subunit: synthesis and p... von Boger, Dale L, Palanki, Moorthy S. S

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Novel inhibitors of AP-1 and NF-κB mediated gene expression: structure–activity relationship studies of ethyl 4-[(3-Methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimid... von Palanki, Moorthy S.S, Erdman, Paul E, Manning, Anthony M, Ow, Arnold, Ransone, Lynn J, Spooner, Cheryl, Suto, Carla, Suto, Mark

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Use of transferred nuclear overhauser effects to determine the conformation of 1-(3,4-dichlorophenyl)-2-aminopropane when bound to the active site of phenylethanolamine N-methyltra... von Grunewald, Gary L., Palanki, Moorthy S.S., Velde, David Vander

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HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH von AYALA, LETICIA, KOIS, ADAM, SAHASRABUDHE, KIRAM, CLAREEN, STEVEN S, DELGADO MEDEROS, MARIA MERCEDES, NADOLNY, LISA, HUGHES, KEVIN, PLANTEVIN-KRENITSKY, VERONIQUE, SLOSS, MARIANNE K, MCCARRICK, MEG, SATOH, YOSHITAKA, SAPIENZA, JOHN, SUDBECK, ELISE, ALBERS, RONALD J, HILGRAF, ROBERT, PALANKI, MOORTHY S.S, WRIGHT, JONATHAN, HEGDE, SAYEE G

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ONE-STEP SYNTHESIS OF TRIFLUOROMETHYL- AND OF METHOXY-SUBSTITUTED BENZYNE PRECURSORS von Grunewald, Gary L., Kolar, Aldean J., Palanki, Moorthy S. S., Paradkar, Vidyadhar M., Reitz, Thomas J., Sall, Daniel J.

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HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH von AYALA, LETICIA, HEGDE, SAYEE,G, KOIS, ADAM, SLOSS, MARIANNE, K, NADOLNY, LISA, HUGHES, KEVIN, ALBERS, RONALD, J, PLANTEVIN-KRENITSKY, VERONIQUE, SAHASRAMUDHE, KIRAN, MCCARRICK, MEG, SATOH, YOSHITAKA, SAPIENZA, JOHN, SUDBECK, ELISE, PALANKI,MOORTHY, S.S, HILGRAF, ROBERT, DELGADO MEDEROS, MARIA, MERCEDES, WRIGHT, JONATHAN, CLAREEN, STEVEN, S

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