An analysis of the attrition of drug candidates from four major pharmaceutical companies von Waring, Michael J., Arrowsmith, John, Leach, Andrew R., Leeson, Paul D., Mandrell, Sam, Owen, Robert M., Pairaudeau, Garry, Pennie, William D., Pickett, Stephen D., Wang, Jibo, Wallace, Owen, Weir, Alex

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A genetically selected cyclic peptide inhibitor of BCL6 homodimerization von Osher, Eliot L., Castillo, Francisco, Elumalai, Nagarajan, Waring, Michael J., Pairaudeau, Garry, Tavassoli, Ali

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Collaborative virtual screening to elaborate an imidazo[1,2-]pyridine hit series for visceral leishmaniasis von Akao, Yuichiro, Canan, Stacie, Cao, Yafeng, Condroski, Kevin, Engkvist, Ola, Itono, Sachiko, Kaki, Rina, Kimura, Chiaki, Kogej, Thierry, Nagaoka, Kazuya, Naito, Akira, Nakai, Hiromi, Pairaudeau, Garry, Radu, Constantin, Roberts, Ieuan, Shimada, Mitsuyuki, Shum, David, Watanabe, Nao-aki, Xie, Huanxu, Yonezawa, Shuji, Yoshida, Osamu, Yoshida, Ryu, Mowbray, Charles, Perry, Benjamin

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From ATP to AZD6140 : The discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis von SPRINGTHORPE, Brian, BAILEY, Andrew, HUNT, Simon F, INCE, Francis, INGALL, Anthony H, KIRK, Ian P, LEESON, Paul D, LEFF, Paul, LEWIS, Richard J, MARTIN, Barrie P, MCGINNITY, Dermot F, MORTIMORE, Michael P, BARTON, Patrick, PAINE, Stuart W, PAIRAUDEAU, Garry, PATEL, Anil, RIGBY, Aaron J, RILEY, Robert J, TEOBALD, Barry J, TOMLINSON, Wendy, WEBBORN, Peter J. H, WILLIS, Paul A, BIRKINSHAW, Timothy N, BONNERT, Roger V, BROWN, Roger C, CHAPMAN, David, DIXON, John, GUILE, Simon D, HUMPHRIES, Robert G

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The convergence of artificial intelligence and chemistry for improved drug discovery von Green, Clive P, Engkvist, Ola, Pairaudeau, Garry

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High Fidelity Suzuki–Miyaura Coupling for the Synthesis of DNA Encoded Libraries Enabled by Micelle Forming Surfactants von Hunter, James H, Prendergast, Lisa, Valente, Louis F, Madin, Andrew, Pairaudeau, Garry, Waring, Michael J

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Creativity, innovation and lean sigma: a controversial combination? von Johnstone, Craig, Pairaudeau, Garry, Pettersson, Jonas A.

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Functional Group Tolerance of a Micellar on-DNA Suzuki–Miyaura Cross-Coupling Reaction for DNA-Encoded Library Design von Hunter, James H, Potowski, Marco, Stanway-Gordon, Harriet A, Madin, Andrew, Pairaudeau, Garry, Brunschweiger, Andreas, Waring, Michael J

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Identification and Development of Cyclic Peptide Inhibitors of Hypoxia Inducible Factors 1 and 2 That Disrupt Hypoxia-Response Signaling in Cancer Cells von Ball, Andrew T., Mohammed, Soran, Doigneaux, Cyrielle, Gardner, Reece M., Easton, James W., Turner, Steven, Essex, Jonathan W., Pairaudeau, Garry, Tavassoli, Ali

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Micelle‐Promoted Reductive Amination of DNA‐Conjugated Amines for DNA‐Encoded Library Synthesis von Anderson, Matthew J., Carton, Thomas P., Salvini, Catherine L. A., Crawford, James J., Pairaudeau, Garry, Waring, Michael J.

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Scope of on-DNA nucleophilic aromatic substitution on weakly-activated heterocyclic substrates for the synthesis of DNA-encoded libraries von Castan, Isaline F.S.F., Madin, Andrew, Pairaudeau, Garry, Waring, Michael J.

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Asymmetric Total Syntheses of (-)- and (+)-Strychnine and the Wieland-Gumlich Aldehyde von Knight, Steven D, Overman, Larry E, Pairaudeau, Garry

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Towards a hit for every target von Rees, Steve, Gribbon, Philip, Birmingham, Karen, Janzen, William P., Pairaudeau, Garry

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Highly efficient on-DNA amide couplings promoted by micelle forming surfactants for the synthesis of DNA encoded libraries von Hunter, James H, Anderson, Matthew J, Castan, Isaline F. S. F, Graham, Jessica S, Salvini, Catherine L. A, Stanway-Gordon, Harriet A, Crawford, James J, Madin, Andrew, Pairaudeau, Garry, Waring, Michael J

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Potent Reversible Inhibition of Myeloperoxidase by Aromatic Hydroxamates von Forbes, Louisa V., Sjögren, Tove, Auchère, Françoise, Jenkins, David W., Thong, Bob, Laughton, David, Hemsley, Paul, Pairaudeau, Garry, Turner, Rufus, Eriksson, Håkan, Unitt, John F., Kettle, Anthony J.

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Collaborative Virtual Screening Identifies a 2‑Aryl-4-aminoquinazoline Series with Efficacy in an In Vivo Model of Trypanosoma cruzi Infection von Tawaraishi, Taisuke, Ochida, Atsuko, Akao, Yuichiro, Itono, Sachiko, Kamaura, Masahiro, Akther, Thamina, Shimada, Mitsuyuki, Canan, Stacie, Chowdhury, Sanjoy, Cao, Yafeng, Condroski, Kevin, Engkvist, Ola, Francisco, Amanda, Ghosh, Sunil, Kaki, Rina, Kelly, John M., Kimura, Chiaki, Kogej, Thierry, Nagaoka, Kazuya, Naito, Akira, Pairaudeau, Garry, Radu, Constantin, Roberts, Ieuan, Shum, David, Watanabe, Nao-aki, Xie, Huanxu, Yonezawa, Shuji, Yoshida, Osamu, Yoshida, Ryu, Mowbray, Charles, Perry, Benjamin

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Collaborative Virtual Screening Identifies a 2-Aryl-4-aminoquinazoline Series with Efficacy in an In Vivo Model of Trypanosoma cruzi Infection von Tawaraishi, Taisuke, Ochida, Atsuko, Akao, Yuichiro, Itono, Sachiko, Kamaura, Masahiro, Akther, Thamina, Shimada, Mitsuyuki, Canan, Stacie, Chowdhury, Sanjoy, Cao, Yafeng, Condroski, Kevin, Engkvist, Ola, Francisco, Amanda, Ghosh, Sunil, Kaki, Rina, Kelly, John M, Kimura, Chiaki, Kogej, Thierry, Nagaoka, Kazuya, Naito, Akira, Pairaudeau, Garry, Radu, Constantin, Roberts, Ieuan, Shum, David, Watanabe, Nao-Aki, Xie, Huanxu, Yonezawa, Shuji, Yoshida, Osamu, Yoshida, Ryu, Mowbray, Charles, Perry, Benjamin

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Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligase von Leitch, Eilidh K, Elumalai, Nagarajan, Fridén-Saxin, Maria, Dahl, Göran, Wan, Paul, Clarkson, Paul, Valeur, Eric, Pairaudeau, Garry, Boyd, Helen, Tavassoli, Ali

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Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligaseElectronic supplementary information... von Leitch, Eilidh K, Elumalai, Nagarajan, Fridén-Saxin, Maria, Dahl, Göran, Wan, Paul, Clarkson, Paul, Valeur, Eric, Pairaudeau, Garry, Boyd, Helen, Tavassoli, Ali

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Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligase† †Electronic supplementary informati... von Leitch, Eilidh K., Elumalai, Nagarajan, Fridén-Saxin, Maria, Dahl, Göran, Wan, Paul, Clarkson, Paul, Valeur, Eric, Pairaudeau, Garry, Boyd, Helen, Tavassoli, Ali

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