Exit from Pluripotency Is Gated by Intracellular Redistribution of the bHLH Transcription Factor Tfe3 von Betschinger, Joerg, Nichols, Jennifer, Dietmann, Sabine, Corrin, Philip D., Paddison, Patrick J., Smith, Austin

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A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency von Hsieh, Emily, Janssens, Derek H, Paddison, Patrick J, Browne, Edward P, Henikoff, Steve, OhAinle, Molly, Emerman, Michael

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Gene knock-outs in human CD34+ hematopoietic stem and progenitor cells and in the human immune system of mice von Kuppers, Daniel A, Linton, Jonathan, Ortiz Espinosa, Sergio, McKenna, Kelly M, Rongvaux, Anthony, Paddison, Patrick J

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Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis von Szulzewsky, Frank, Arora, Sonali, Hoellerbauer, Pia, King, Claire, Nathan, Erica, Chan, Marina, Cimino, Patrick J, Ozawa, Tatsuya, Kawauchi, Daisuke, Pajtler, Kristian W, Gilbertson, Richard J, Paddison, Patrick J, Vasioukhin, Valeri, Gujral, Taranjit S, Holland, Eric C

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Transcription elongation factors represent in vivo cancer dependencies in glioblastoma von Miller, Tyler E., Liau, Brian B., Wallace, Lisa C., Morton, Andrew R., Xie, Qi, Dixit, Deobrat, Factor, Daniel C., Kim, Leo J. Y., Morrow, James J., Wu, Qiulian, Mack, Stephen C., Hubert, Christopher G., Gillespie, Shawn M., Flavahan, William A., Hoffmann, Thomas, Thummalapalli, Rohit, Hemann, Michael T., Paddison, Patrick J., Horbinski, Craig M., Zuber, Johannes, Scacheri, Peter C., Bernstein, Bradley E., Tesar, Paul J., Rich, Jeremy N.

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Wnt and TGF-β Signaling Are Required for the Induction of an in vitro Model of Primitive Streak Formation Using Embryonic Stem Cells von Gadue, Paul, Huber, Tara L., Paddison, Patrick J., Keller, Gordon M.

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Ion channel expression patterns in glioblastoma stem cells with functional and therapeutic implications for malignancy von Pollak, Julia, Rai, Karan G, Funk, Cory C, Arora, Sonali, Lee, Eunjee, Zhu, Jun, Price, Nathan D, Paddison, Patrick J, Ramirez, Jan-Marino, Rostomily, Robert C

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G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment von Chen, Xiaoji, Skutt-Kakaria, Kyobi, Davison, Jerry, Ou, Yang-Li, Choi, Edward, Malik, Punam, Loeb, Keith, Wood, Brent, Georges, George, Torok-Storb, Beverly, Paddison, Patrick J

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Both YAP1-MAML2 and constitutively active YAP1 drive the formation of tumors that resemble NF2 mutant meningiomas in mice von Szulzewsky, Frank, Arora, Sonali, Arakaki, Aleena K S, Sievers, Philipp, Almiron Bonnin, Damian A, Paddison, Patrick J, Sahm, Felix, Cimino, Patrick J, Gujral, Taranjit S, Holland, Eric C

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Functional dissection of human mitotic genes using CRISPR-Cas9 tiling screens von Herman, Jacob A, Arora, Sonali, Carter, Lucas, Zhu, Jun, Biggins, Sue, Paddison, Patrick J

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A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways von Pattwell, Siobhan S., Arora, Sonali, Cimino, Patrick J., Ozawa, Tatsuya, Szulzewsky, Frank, Hoellerbauer, Pia, Bonifert, Tobias, Hoffstrom, Benjamin G., Boiani, Norman E., Bolouri, Hamid, Correnti, Colin E., Oldrini, Barbara, Silber, John R., Squatrito, Massimo, Paddison, Patrick J., Holland, Eric C.

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Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones von Sarthy, Jay F, Meers, Michael P, Janssens, Derek H, Henikoff, Jorja G, Feldman, Heather, Paddison, Patrick J, Lockwood, Christina M, Vitanza, Nicholas A, Olson, James M, Ahmad, Kami, Henikoff, Steven

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Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A von Hubert, Christopher G, Bradley, Robert K, Ding, Yu, Toledo, Chad M, Herman, Jacob, Skutt-Kakaria, Kyobi, Girard, Emily J, Davison, Jerry, Berndt, Jason, Corrin, Philip, Hardcastle, Justin, Basom, Ryan, Delrow, Jeffery J, Webb, Thomas, Pollard, Steven M, Lee, Jeongwu, Olson, James M, Paddison, Patrick J

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Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells von Paddison, Patrick J, Caudy, Amy A, Bernstein, Emily, Hannon, Gregory J, Conklin, Douglas S

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Neural G0: a quiescent‐like state found in neuroepithelial‐derived cells and glioma von O’Connor, Samantha A, Feldman, Heather M, Arora, Sonali, Hoellerbauer, Pia, Toledo, Chad M, Corrin, Philip, Carter, Lucas, Kufeld, Megan, Bolouri, Hamid, Basom, Ryan, Delrow, Jeffrey, McFaline‐Figueroa, José L, Trapnell, Cole, Pollard, Steven M, Patel, Anoop, Paddison, Patrick J, Plaisier, Christopher L

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N 6 -methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis von Kuppers, Daniel A, Arora, Sonali, Lim, Yiting, Lim, Andrea R, Carter, Lucas M, Corrin, Philip D, Plaisier, Christopher L, Basom, Ryan, Delrow, Jeffrey J, Wang, Shiyan, Hansen He, Housheng, Torok-Storb, Beverly, Hsieh, Andrew C, Paddison, Patrick J

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BuGZ facilitates loading of spindle assembly checkpoint proteins to kinetochores in early mitosis von Shirnekhi, Hazheen K., Herman, Jacob A., Paddison, Patrick J., DeLuca, Jennifer G.

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Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia von Wendel, Hans-Guido, Zuber, Johannes, Leslie, Christina S, McJunkin, Katherine, Paddison, Patrick J, Ferrando, Adolfo, Khan, Aly A, Tam, Wayne, Parker, Joel S, Wolfe, Andrew L, de Keersmaecker, Kim, Mavrakis, Konstantinos J, Palomero, Teresa, James, Taneisha, Oricchio, Elisa

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Efficient Multi‐Allelic Genome Editing of Primary Cell Cultures via CRISPR‐Cas9 Ribonucleoprotein Nucleofection von Hoellerbauer, Pia, Kufeld, Megan, Paddison, Patrick J.

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WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma von Mitchell, Kelly, Sprowls, Samuel A, Arora, Sonali, Shakya, Sajina, Silver, Daniel J, Goins, Christopher M, Wallace, Lisa, Roversi, Gustavo, Schafer, Rachel E, Kay, Kristen, Miller, Tyler E, Lauko, Adam, Bassett, John, Kashyap, Anjali, D'Amato Kass, Jonathan, Mulkearns-Hubert, Erin E, Johnson, Sadie, Alvarado, Joseph, Rich, Jeremy N, Holland, Eric C, Paddison, Patrick J, Patel, Anoop P, Stauffer, Shaun R, Hubert, Christopher G, Lathia, Justin D

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