Unlocking methodological insights on oncology efficacy endpoints: from statistical to clinical and vice versa. Letter to the editor regarding ‘Abemaciclib plus a nonsteroidal aroma... von De Sanctis, R., Bruzzi, P., Zambelli, A.

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Ovarian suppression using luteinizing hormone-releasing hormone agonists during chemotherapy to preserve ovarian function and fertility of breast cancer patients: a meta-analysis o... von Lambertini, M., Ceppi, M., Poggio, F., Peccatori, F.A., Azim, H.A., Ugolini, D., Pronzato, P., Loibl, S., Moore, H.C.F., Partridge, A.H., Bruzzi, P., Del Mastro, L.

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Metformin plus chemotherapy versus chemotherapy alone in the first-line treatment of HER2-negative metastatic breast cancer. The MYME randomized, phase 2 clinical trial von Nanni, O., Amadori, D., De Censi, A., Rocca, A., Freschi, A., Bologna, A., Gianni, L., Rosetti, F., Amaducci, L., Cavanna, L., Foca, F., Sarti, S., Serra, P., Valmorri, L., Bruzzi, P., Corradengo, D., Gennari, A.

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Endocrine and metabolic complications in children and adolescents with Sickle Cell Disease: an Italian cohort study von Mandese, V, Bigi, E, Bruzzi, P, Palazzi, G, Predieri, B, Lucaccioni, L, Cellini, M, Iughetti, L

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Surrogate endpoints for EDSS worsening in multiple sclerosis: A meta-analytic approach von SORMANI, M. P, BONZANO, L, ROCCATAGLIATA, L, MANCARDI, G. L, UCCELLI, A, BRUZZI, P

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Rare Cancers Europe (RCE) methodological recommendations for clinical studies in rare cancers: a European consensus position paper von Casali, P.G., Bruzzi, P., Bogaerts, J., Blay, J.-Y., Aapro, M., Adamous, A., Berruti, A., Blay, J.-Y., Bogaerts, J., Bressington, J., Bruzzi, B., Capocaccia, R., Cardoso, F., Casali, P.G., Celis, J.E., Cervantes, A., Ciardiello, F., Claussen, C., Coleman, M., Comis, S., Craine, S., De Boltz, D., De Lorenzo, F., Dei Tos, A.P., Gatta, G., Geissler, J., Giuliani, R., Grande, E., Gronchi, A., Jezdic, S., Jonsson, B., Jost, L., Keulen, H., Lacombe, D., Lamory, G., Le Cam, Y., Leto di Priolo, S., Licitra, L., Macchia, F., Margulies, A., Marreaud, S., McVie, G., Narbutas, S., Oliver, K., Pavlidis, N., Pelouchova, J., Pentheroudakis, G., Piccart, M., Pierotti, M.A., Pravettoni, G., Redmond, K., Riegman, P., Ruffilli, M.P., Ryner, D., Sandrucci, S., Seymour, M., Torri, V., Trama, A., Van Belle, S., Vassal, G., Wartenberg, M., Watts, C., Wilson, A., Yared, W.

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Role of micronucleus test in predicting breast cancer susceptibility: a systematic review and meta-analysis von Cardinale, F, Bruzzi, P, Bolognesi, C

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Combined MRI lesions and relapses as a surrogate for disability in multiple sclerosis von SORMANI, M. P, LI, D. K, BRUZZI, P, STUBINSKI, B, CORNELISSE, P, ROCAK, S, DE STEFANO, N

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Sentinel node biopsy compared with complete axillary dissection for staging early breast cancer with clinically negative lymph nodes: results of randomized trial von Canavese, G., Catturich, A., Vecchio, C., Tomei, D., Gipponi, M., Villa, G., Carli, F., Bruzzi, P., Dozin, B.

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Mortality after bloodstream infections in allogeneic haematopoietic stem cell transplant (HSCT) recipients von Mikulska, M., Del Bono, V., Bruzzi, P., Raiola, A. M., Gualandi, F., Van Lint, M. T., Bacigalupo, A., Viscoli, C.

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Previous bloodstream infections due to other pathogens as predictors of carbapenem-resistant Klebsiella pneumoniae bacteraemia in colonized patients: results from a retrospective m... von Giacobbe, D. R., Del Bono, V., Bruzzi, P., Corcione, S., Giannella, M., Marchese, A., Magnasco, L., Maraolo, A. E., Pagani, N., Saffioti, C., Ambretti, S., Cardellino, C. S., Coppo, E., De Rosa, F. G., Viale, P., Viscoli, C.

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Difficulties in conducting pure academic research, obstacles in data collection and quality of informations: The example of the INTERCEPTOR study von Merlano, M, Denaro, N, Benasso, M, Licitra, L, Bossi, P, Locati, L, Vecchio, S, Bruzzi, P

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Breast cancer incidence trends in European women aged 20–39 years at diagnosis von Merlo, D. F., Ceppi, M., Filiberti, R., Bocchini, V., Znaor, A., Gamulin, M., Primic-Žakelj, M., Bruzzi, P., Bouchardy, C., Fucic, A.

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Autologous haematopoietic stem cell transplantation with an intermediate intensity conditioning regimen in multiple sclerosis: the Italian multi-centre experience von Mancardi, GL, Sormani, MP, Di Gioia, M, Vuolo, L, Gualandi, F, Amato, MP, Capello, E, Currò, D, Uccelli, A, Bertolotto, A, Gasperini, C, Lugaresi, A, Merelli, E, Meucci, G, Motti, L, Tola, MR, Scarpini, E, Repice, AM, Massacesi, L, Saccardi, R, Donnini, I, Bosi, A, Guidi, S, Bagigalupo, A, Bonzano, L, Bruzzi, P, Roccatagliata, L, Antenucci, R, Granella, F, Martino, G, Rottoli, M, Solaro, C, Salvi, F, Barilaro, A, Capobianco, M

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Initial serum (1,3)-β-d-glucan as a predictor of mortality in proven candidaemia: findings from a retrospective study in two teaching hospitals in Italy and Brazil von Giacobbe, D.R., Esteves, P., Bruzzi, P., Mikulska, M., Furfaro, E., Mesini, A., Tatarelli, P., Grignolo, S., Viscoli, C., Colombo, A.L., Del Bono, V.

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Treatment of localised resectable neuroblastoma. Results of the LNESG1 study by the SIOP Europe Neuroblastoma Group von De Bernardi, B, Mosseri, V, Rubie, H, Castel, V, Foot, A, Ladenstein, R, Laureys, G, Beck-Popovic, M, de Lacerda, A F, Pearson, A D J, De Kraker, J, Ambros, P F, de Rycke, Y, Conte, M, Bruzzi, P, Michon, J

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International Expert Consensus on Primary Systemic Therapy in the Management of Early Breast Cancer: Highlights of the Fourth Symposium on Primary Systemic Therapy in the Managemen... von Berruti, Alfredo, Generali, Daniele, Kaufmann, Manfred, Puztai, Lajos, Curigliano, Giuseppe, Aglietta, Massimo, Gianni, Luca, Miller, William R., Untch, Michael, Sotiriou, Christos, Daidone, Mariagrazia, Conte, PierFranco, Kennedy, Derek, Damia, Giovanna, Petronini, Piergiorgio, Di Cosimo, Serena, Bruzzi, Paolo, Dowsett, Mitch, Desmedt, Christine, Mansel, Robert E., Olivetti, Lucio, Tondini, Carlo, Sapino, Anna, Fenaroli, Privato, Tortora, Gianpaolo, Thorne, Hather, Bertolini, Francesco, Ferrozzi, Francesco, Danova, Marco, Tagliabue, Elda, de Azambuja, Evandro, Makris, Andreas, Tampellini, Marco, Dontu, Gabriela, Van't Veer, Laura, Harris, Adrian L., Fox, Stephen B., Dogliotti, Luigi, Bottini, Alberto

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Diagnosis and prognosis disclosure among cancer patients. Results from an Italian mortality follow-back survey von Costantini, M., Morasso, G., Montella, M., Borgia, P., Cecioni, R., Beccaro, M., Sguazzotti, E., Bruzzi, P.

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Concurrent versus sequential adjuvant chemo-endocrine therapy in hormone-receptor positive early stage breast cancer patients: a systematic review and meta-analysis von Poggio, F, Ceppi, M, Lambertini, M, Bruzzi, P, Ugolini, D, Bighin, C, Levaggi, A, Giraudi, S, D'Alonzo, A, Vaglica, M, Blondeaux, E, Sertoli, M.R, Pronzato, P, Del Mastro, L., MD

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210 Genetic and epigenetic factors affect RET gene expression in breast cancer cell lines and influence survival in patients von Griseri, P, Garrone, O, Lo Sardo, A, Monteverde, M, Rusmini, M, Tonissi, F, Merlano, M, Bruzzi, P, Ceccherini, I, Nigro, C. Lo

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