Identification of 2‑(4-(Phenylsulfonyl)piperazine-1-yl)pyrimidine Analogues as Novel Inhibitors of Chikungunya Virus von Moesslacher, Julia, Battisti, Verena, Delang, Leen, Neyts, Johan, Abdelnabi, Rana, Pürstinger, Gerhard, Urban, Ernst, Langer, Thierry

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Allosteric Regulation of Phosphatidylinositol 4‑Kinase III Beta by an Antipicornavirus Compound MDL-860 von Arita, Minetaro, Dobrikov, Georgi, Pürstinger, Gerhard, Galabov, Angel S

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The Thiazolobenzimidazole TBZE-029 Inhibits Enterovirus Replication by Targeting a Short Region Immediately Downstream from Motif C in the Nonstructural Protein 2C von De Palma, Armando M, Heggermont, Ward, Lanke, Kjerstin, Coutard, Bruno, Bergmann, Mirko, Monforte, Anna-Maria, Canard, Bruno, De Clercq, Erik, Chimirri, Alba, Pürstinger, Gerhard, Rohayem, Jacques, van Kuppeveld, Frank, Neyts, Johan

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Quinolinecarboxamides Inhibit the Replication of the Bovine Viral Diarrhea Virus by Targeting a Hot Spot for the Inhibition of Pestivirus Replication in the RNA-Dependent RNA Polym... von Musiu, Simone, Castillo, Yunierkis Perez, Muigg, Alexandra, Pürstinger, Gerhard, Leyssen, Pieter, Froeyen, Mathy, Neyts, Johan, Paeshuyse, Jan

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The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family von van der Linden, Lonneke, Vives-Adrián, Laia, Selisko, Barbara, Ferrer-Orta, Cristina, Liu, Xinran, Lanke, Kjerstin, Ulferts, Rachel, De Palma, Armando M, Tanchis, Federica, Goris, Nesya, Lefebvre, David, De Clercq, Kris, Leyssen, Pieter, Lacroix, Céline, Pürstinger, Gerhard, Coutard, Bruno, Canard, Bruno, Boehr, David D, Arnold, Jamie J, Cameron, Craig E, Verdaguer, Nuria, Neyts, Johan, van Kuppeveld, Frank J M

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Mechanistic Characterization of GS-9190 (Tegobuvir), a Novel Nonnucleoside Inhibitor of Hepatitis C Virus NS5B Polymerase von Shih, I-Hung, Vliegen, Inge, Peng, Betty, Yang, Huiling, Hebner, Christy, Paeshuyse, Jan, Pürstinger, Gerhard, Fenaux, Martijn, Tian, Yang, Mabery, Eric, Qi, Xiaoping, Bahador, Gina, Paulson, Matthew, Lehman, Laura S, Bondy, Steven, Tse, Winston, Reiser, Hans, Lee, William A, Schmitz, Uli, Neyts, Johan, Zhong, Weidong

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Potential use of antiviral agents in polio eradication von De Palma, Armando M, Pürstinger, Gerhard, Wimmer, Eva, Patick, Amy K, Andries, Koen, Rombaut, Bart, De Clercq, Erik, Neyts, Johan

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Anti-enteroviral triple combination of viral replication inhibitors: activity against coxsackievirus B1 neuroinfection in mice von Stoyanova, Adelina, Nikolova, Ivanka, Pürstinger, Gerhard, Dobrikov, Georgi, Dimitrov, Vladimir, Philipov, Stefan, Galabov, Angel S

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Synthesis, Cytotoxic, and Antitumor Activities of 2-Pyridylhydrazones Derived from 3-Benzoylpyridazines von Easmon, Johnny, Pürstinger, Gerhard, Heinisch, Gottfried, Fiebig, Hans H., Roth, Thomas, Hofmann, Johann

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Synthesis, Structure−Activity Relationships, and Antitumor Studies of 2-Benzoxazolyl Hydrazones Derived from Alpha-(N)-acyl Heteroaromatics von Easmon, Johnny, Pürstinger, Gerhard, Thies, Katrin-Sofia, Heinisch, Gottfried, Hofmann, Johann

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Synthesis and anti-CVB 3 evaluation of substituted 5-nitro-2-phenoxybenzonitriles von Pürstinger, Gerhard, De Palma, Armando M., Zimmerhofer, Günther, Huber, Simone, Ladurner, Sophie, Neyts, Johan

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Substituted 2,6-bis(benzimidazol-2-yl)pyridines: A novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-depende... von Musiu, Simone, Pürstinger, Gerhard, Stallinger, Sylvia, Vrancken, Robert, Haegeman, Andy, Koenen, Frank, Leyssen, Pieter, Froeyen, Mathy, Neyts, Johan, Paeshuyse, Jan

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Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication von van der Schaar, Hilde M, van der Linden, Lonneke, Lanke, Kjerstin H W, Strating, Jeroen R P M, Pürstinger, Gerhard, de Vries, Erik, de Haan, Cornelis A M, Neyts, Johan, van Kuppeveld, Frank J M

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Substituted 2,6-bis(benzimidazol-2-yl)pyridines: A novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-depende... von Musiu, Simone, Pürstinger, Gerhard, Stallinger, Sylvia, Vrancken, Robert, Haegeman, Andy, Koenen, Frank, Leyssen, Pieter, Froeyen, Mathy, Neyts, Johan, Paeshuyse, Jan

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Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 Inhibitors von Kovacikova, Kristina, Gorostiola González, Marina, Jones, Rhian, Reguera, Juan, Gigante, Alba, Pérez-Pérez, María-Jesús, Pürstinger, Gerhard, Moesslacher, Julia, Langer, Thierry, Jeong, Lak Shin, Delang, Leen, Neyts, Johan, Snijder, Eric J, van Westen, Gerard J P, van Hemert, Martijn J

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Coxsackievirus mutants that can bypass host factor PI4KIII[beta] and the need for high levels of PI4P lipids for replication von Van Der Schaar, Hilde M, Van Der Linden, Lonneke, Lanke, Kjerstin H W, Strating, Jeroen R P M, Pürstinger, Gerhard, De Vries, Erik, De Haan, Cornelis A M, Neyts, Johan, Van Kuppeveld, Frank J M

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In Vitro Combination Therapy with Tegobuvir (GS-9190) is Highly Efficient in Curing Cells from HCV Replicon and in Delaying/Preventing the Development of Antiviral Resistance von Vliegen, Inge, Paeshuyse, Jan, Shih, I-hung, Pürstinger, Gerhard, Bondy, Steven, Lee, William A., Zhong, Weidong, Neyts, Johan

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Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor von Vrancken, Robert, Haegeman, Andy, Paeshuyse, Jan, Pürstinger, Gerhard, Rozenski, Jef, Wright, Matthew, Tignon, Marylène, Le Potier, Marie-Frédérique, Neyts, Johan, Koenen, Frank

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Potential Use of Antiviral Agents in Polio Eradication von De Palma, Armando M, Puerstinger, Gerhard, Wimmer, Eva, Patick, Amy K, Andries, Koen, Rombaut, Bart, De Clercq, Erik, Neyts, Johan

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H1PVAT is a novel and potent early-stage inhibitor of poliovirus replication that targets VP1 von TIJSMA, Aloys, THIBAUT, Hendrik Jan, MARCHAND, Arnaud, CHALTIN, Patrick, NEYTS, Johan, LEYSSEN, Pieter, SPIESER, Stéphane A. H, DE PALMA, Armando, KOUKNI, Mohamed, RHODEN, Eric, OBERSTE, Steve, PÜRSTINGER, Gerhard, VOLNY-LURAGHI, Antonia, MARTIN, Javier

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