The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancer von López‐Plana, Anna, Fernández‐Nogueira, Patricia, Muñoz‐Guardiola, Pau, Solé‐Sánchez, Sònia, Megías‐Roda, Elisabet, Pérez‐Montoyo, Héctor, Jauregui, Patricia, Yeste‐Velasco, Marc, Gómez‐Ferreria, Mariana, Erazo, Tatiana, Ametller, Elisabet, Recalde‐Percaz, Leire, Moragas‐Garcia, Núria, Noguera‐Castells, Aleix, Mancino, Mario, Morán, Teresa, Nadal, Ernest, Alfón, José, Domènech, Carles, Gascon, Pere, Lizcano, Jose M., Fuster, Gemma, Bragado, Paloma

Volltext

Therapeutic potential of the new TRIB3-mediated cell autophagy anticancer drug ABTL0812 in endometrial cancer von Felip, Isidre, Moiola, Cristian Pablo, Megino-Luque, Cristina, Lopez-Gil, Carlos, Cabrera, Silvia, Solé-Sánchez, Sonia, Muñoz-Guardiola, Pau, Megias-Roda, Elisabet, Pérez-Montoyo, Héctor, Alfon, José, Yeste-Velasco, Marc, Santacana, María, Dolcet, Xavier, Reques, Armando, Oaknin, Ana, Rodríguez-Freixinos, Victor, Lizcano, José Miguel, Domènech, Carles, Gil-Moreno, Antonio, Matias-Guiu, Xavier, Colas, Eva, Eritja, Nuria

Volltext

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice von Montoyo, Héctor Pérez, Vaccaro, Carlos, Hafner, Martin, Ober, Raimund J, Mueller, Werner, Ward, E. Sally

Volltext

Correction: ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with adv... von Leary, Alexandra, Estévez-García, Purificación, Sabatier, Renaud, Ray-Coquard, Isabelle, Romeo, Margarita, Barretina-Ginesta, Pilar, Gil-Martin, Marta, Garralda, Elena, Bosch-Barrera, Joaquim, Morán, Teresa, Martin-Martorell, Paloma, Nadal, Ernest, Gascón, Pere, Rodon, Jordi, Lizcano, Jose M, Muéoz-Guardiola, Pau, Fierro-Durán, Gemma, Pedrós-Gámez, Oriol, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Cortal, Marc, Pérez-Campos, Antonio, Alfon, Jose, Domenech, Carles, Pérez-Fidalgo, Alejandro, Oaknin, Ana

Volltext

ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurr... von Leary, Alexandra, Estévez-García, Purificación, Sabatier, Renaud, Ray-Coquard, Isabelle, Romeo, Margarita, Barretina-Ginesta, Pilar, Gil-Martin, Marta, Garralda, Elena, Bosch-Barrera, Joaquim, Morán, Teresa, Martin-Martorell, Paloma, Nadal, Ernest, Gascón, Pere, Rodon, Jordi, Lizcano, Jose M, Muñoz-Guardiola, Pau, Fierro-Durán, Gemma, Pedrós-Gámez, Oriol, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Cortal, Marc, Pérez-Campos, Antonio, Alfon, Jose, Domenech, Carles, Pérez-Fidalgo, Alejandro, Oaknin, Ana

Volltext

Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis von Challa, Dilip K, Wang, Xiaoli, Montoyo, Héctor Pérez, Velmurugan, Ramraj, Ober, Raimund J, Ward, E Sally

Volltext

Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population von Gómez-Miragaya, Jorge, Palafox, Marta, Paré, Laia, Yoldi, Guillermo, Ferrer, Irene, Vila, Sergi, Galván, Patricia, Pellegrini, Pasquale, Pérez-Montoyo, Hector, Igea, Ana, Muñoz, Purificación, Esteller, Manel, Nebreda, Angel R., Urruticoechea, Ander, Morilla, Idoia, Pernas, Sonia, Climent, Fina, Soler-Monso, María Teresa, Petit, Ana, Serra, Violeta, Prat, Aleix, González-Suárez, Eva

Volltext

Neonatal Fc receptor blockade by Fc engineering ameliorates arthritis in a murine model von Patel, Dipesh A, Puig-Canto, Alberto, Challa, Dilip Kumar, Perez Montoyo, Héctor, Ober, Raimund J, Ward, E Sally

Volltext

Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models von Mancini, Andrea, Colapietro, Alessandro, Cristiano, Loredana, Rossetti, Alessandra, Mattei, Vincenzo, Gravina, Giovanni Luca, Perez-Montoyo, Héctor, Yeste-Velasco, Marc, Alfon, Jose, Domenech, Carles, Festuccia, Claudio

Volltext

Therapeutic Potential of Autophagy Modulation in Cholangiocarcinoma von Perez-Montoyo, Hector

Volltext

RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer von Ciscar, Marina, Trinidad, Eva M, Perez‐Chacon, Gema, Alsaleem, Mansour, Jimenez, Maria, Jimenez‐Santos, Maria J, Perez‐Montoyo, Hector, Sanz‐Moreno, Adrian, Vethencourt, Andrea, Toss, Michael, Petit, Anna, Soler‐Monso, Maria T, Lopez, Victor, Gomez‐Miragaya, Jorge, Gomez‐Aleza, Clara, Dobrolecki, Lacey E, Lewis, Michael T, Bruna, Alejandra, Mouron, Silvana, Quintela‐Fandino, Miguel, Al‐Shahrour, Fatima, Martinez‐Aranda, Antonio, Sierra, Angels, Green, Andrew R, Rakha, Emad, Gonzalez‐Suarez, Eva

Volltext

ABTL0812 enhances antitumor effect of paclitaxel and reverts chemoresistance in triple‐negative breast cancer models von Polonio‐Alcalá, Emma, Solé‐Sánchez, Sònia, Muñoz‐Guardiola, Pau, Megías‐Roda, Elisabet, Perez‐Montoyo, Héctor, Yeste‐Velasco, Marc, Alfón, Jose, Lizcano, Jose Miguel, Domènech, Carles, Ruiz‐Martínez, Santiago, Puig, Teresa

Volltext

The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells von Muñoz-Guardiola, Pau, Casas, Josefina, Megías-Roda, Elisabet, Solé, Sònia, Perez-Montoyo, Héctor, Yeste-Velasco, Marc, Erazo, Tatiana, Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Muñoz-Pinedo, Cristina, Yoldi, Guillermo, Abad, Jose L, Segura, Miguel F, Moran, Teresa, Romeo, Margarita, Bosch-Barrera, Joaquim, Oaknin, Ana, Alfón, Jose, Domènech, Carles, Fabriàs, Gemma, Velasco, Guillermo, Lizcano, Jose M

Volltext

Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells von Cánovas, Begoña, Igea, Ana, Sartori, Alessandro A., Gomis, Roger R., Paull, Tanya T., Isoda, Michitaka, Pérez-Montoyo, Héctor, Serra, Violeta, González-Suárez, Eva, Stracker, Travis H., Nebreda, Angel R.

Volltext

Phase 2 clinical trial of the proautophagic drug ABTL0812 combined with paclitaxel and carboplatin in first-line patients with advanced squamous non-small cell lung carcinoma von Bosch-Barrera, Joaquim, Moran, Teresa, Estévez-García, Purificación, Martín-Martorell, Paloma, Sabatier, Renaud, Nadal, Ernest, Lizcano, Jose M., Pedrós-Gámez, Oriol, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Domenech, Carles, Alfon, Jose Alberto

Volltext

The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival von Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Yoldi, Guillermo, Megías-Roda, Elisabet, Bolinaga-Ayala, Idoia, Viñas-Casas, Maria, Gorgisen, Gokhan, Domingo-Ortí, Inés, Pérez-Montoyo, Héctor, Bayascas, Jose R., Colas, Eva, Dolcet, Xavier, Lizcano, Jose M.

Volltext

Correction: ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with adv... von Leary, Alexandra, Estévez-García, Purificación, Sabatier, Renaud, Ray-Coquard, Isabelle, Romeo, Margarita, Barretina-Ginesta, Pilar, Gil-Martin, Marta, Garralda, Elena, Bosch-Barrera, Joaquim, Morán, Teresa, Martin-Martorell, Paloma, Nadal, Ernest, Gascón, Pere, Rodon, Jordi, Lizcano, Jose M, Muñoz-Guardiola, Pau, Fierro-Durán, Gemma, Pedrós-Gámez, Oriol, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Cortal, Marc, Pérez-Campos, Antonio, Alfon, Jose, Domenech, Carles, Pérez-Fidalgo, Alejandro, Oaknin, Ana

Volltext

Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells von Cánovas, Begoña, Igea, Ana, Sartori, Alessandro A, Gomis, Roger R, Paull, Tanya T, Isoda, Michitaka, Pérez-Montoyo, Héctor, Serra, Violeta, González-Suárez, Eva, Stracker, Travis H, Nebreda, Angel R

Volltext

The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis von París-Coderch, Laia, Soriano, Aroa, Jiménez, Carlos, Erazo, Tatiana, Muñoz-Guardiola, Pau, Masanas, Marc, Antonelli, Roberta, Boloix, Ariadna, Alfón, José, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Domènech, Carles, Roma, Josep, Sánchez de Toledo, Josep, Moreno, Lucas, Lizcano, José M., Gallego, Soledad, Segura, Miguel F.

Volltext

Development of TRIB3 as a novel preclinical and clinical pharmacodynamic biomarker for ABTL0812 von Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Solé-Sánchez, Sònia, Bragado, Paloma, Colàs-Ortega, Eva, Eritja, Nuria, Lopez-Plana, Anna, Fernandez-Nogueira, Patricia, Muñoz-Guardiola, Pau, Megías-Roda, Elisabet, Moiola, Cristian, Felip, Isidre, Nadal-Alforja, Ernest, Gil Martin, Marta, Romeo, Margarita, Moran, Teresa, Gil-Moreno, Antonio, Matias-Guiu, Xavier, Domenech, Carles, Lizcano, Jose M

Volltext