40 YEARS OF IGF1: PAPP-A and cancer von Conover, Cheryl A, Oxvig, Claus

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Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism von Kobberø, Sara Dam, Gajhede, Michael, Mirza, Osman Asghar, Kløverpris, Søren, Kjær, Troels Rønn, Mikkelsen, Jakob Hauge, Boesen, Thomas, Oxvig, Claus

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The role of PAPP-A in the IGF system: location, location, location von Oxvig, Claus

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The structural basis of calcium transport by the calcium pump von Olesen, Claus, Picard, Martin, Winther, Anne-Marie Lund, Gyrup, Claus, Morth, J. Preben, Oxvig, Claus, Møller, Jesper Vuust, Nissen, Poul

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Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A von Kløverpris, Søren, Mikkelsen, Jakob H., Pedersen, Josefine H., Jepsen, Malene R., Laursen, Lisbeth S., Petersen, Steen V., Oxvig, Claus

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Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion von Heitzeneder, Sabine, Sotillo, Elena, Shern, Jack F, Sindiri, Sivasish, Xu, Peng, Jones, Robert, Pollak, Michael, Noer, Pernille R, Lorette, Julie, Fazli, Ladan, Alag, Anya, Meltzer, Paul, Lau, Ching, Conover, Cheryl A, Oxvig, Claus, Sorensen, Poul H, Maris, John M, Khan, Javed, Mackall, Crystal L

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The metalloproteinase Papp-aa controls epithelial cell quiescence-proliferation transition von Liu, Chengdong, Li, Shuang, Noer, Pernille Rimmer, Kjaer-Sorensen, Kasper, Juhl, Anna Karina, Goldstein, Allison, Ke, Caihuan, Oxvig, Claus, Duan, Cunming

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One level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiology von Argente, Jesús, Chowen, Julie A, Pérez‐Jurado, Luis A, Frystyk, Jan, Oxvig, Claus

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Dosage of the pseudoautosomal gene SLC25A6 is implicated in QTc interval duration von Skakkebæk, Anne, Kjær-Sørensen, Kasper, Matchkov, Vladimir V., Christensen, Lise-Lotte, Just, Jesper, Cömert, Cagla, Andersen, Niels Holmark, Oxvig, Claus, Gravholt, Claus Højbjerg

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Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome von Thorsen, Kasper, Dam, Vibeke S., Kjaer-Sorensen, Kasper, Pedersen, Lisbeth N., Skeberdis, V. Arvydas, Jurevičius, Jonas, Treinys, Rimantas, Petersen, Ida M. B. S., Nielsen, Morten S., Oxvig, Claus, Morth, J. Preben, Matchkov, Vladimir V., Aalkjær, Christian, Bundgaard, Henning, Jensen, Henrik K.

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The metalloproteinase PAPP-A is required for IGF-dependent chondrocyte differentiation and organization von Harboe, Mette, Kjaer-Sorensen, Kasper, Füchtbauer, Ernst-Martin, Fenton, Robert A., Thomsen, Jesper Skovhus, Brüel, Annemarie, Oxvig, Claus

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Pregnancy associated plasma protein-A2 (PAPP-A2) and stanniocalcin-2 (STC2) but not PAPP-A are associated with circulating total IGF-1 in a human adult population von Nimptsch, Katharina, Aydin, Elif Ece, Chavarria, Rafael Francisco Rios, Janke, Jürgen, Poy, Matthew N., Oxvig, Claus, Steinbrecher, Astrid, Pischon, Tobias

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Mutations in pregnancy‐associated plasma protein A2 cause short stature due to low IGF‐I availability von Dauber, Andrew, Muñoz‐Calvo, María T, Barrios, Vicente, Domené, Horacio M, Kloverpris, Soren, Serra‐Juhé, Clara, Desikan, Vardhini, Pozo, Jesús, Muzumdar, Radhika, Martos‐Moreno, Gabriel Á, Hawkins, Federico, Jasper, Héctor G, Conover, Cheryl A, Frystyk, Jan, Yakar, Shoshana, Hwa, Vivian, Chowen, Julie A, Oxvig, Claus, Rosenfeld, Ron G, Pérez‐Jurado, Luis A, Argente, Jesús

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SorCS2 binds progranulin to regulate motor neuron development von Thomasen, Pernille Bogetofte, Salasova, Alena, Kjaer-Sorensen, Kasper, Woloszczuková, Lucie, Lavický, Josef, Login, Hande, Tranberg-Jensen, Jeppe, Almeida, Sergio, Beel, Sander, Kavková, Michaela, Qvist, Per, Kjolby, Mads, Ovesen, Peter Lund, Nolte, Stella, Vestergaard, Benedicte, Udrea, Andreea-Cornelia, Nejsum, Lene Niemann, Chao, Moses V., Van Damme, Philip, Krivanek, Jan, Dasen, Jeremy, Oxvig, Claus, Nykjaer, Anders

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Assessing metabolic rates in zebrafish using a 3D-printed intermittent-flow respirometer and swim tunnel system von Hejlesen, Rasmus, Scheffler, Freja Burkarl, Byrge, Clara Garfiel, Kjær-Sørensen, Kasper, Oxvig, Claus, Fago, Angela, Malte, Hans

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Severe Preeclampsia-Related Changes in Gene Expression at the Maternal-Fetal Interface Include Sialic Acid-Binding Immunoglobulin-Like Lectin-6 and Pappalysin-2 von Winn, Virginia D, Gormley, Matthew, Paquet, Agnes C, Kjaer-Sorensen, Kasper, Kramer, Anita, Rumer, Kristen K, Haimov-Kochman, Ronit, Yeh, Ru-Fang, Overgaard, Michael T, Varki, Ajit, Oxvig, Claus, Fisher, Susan J

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The pro-atherogenic enzyme PAPP-A is active in eluates from human carotid and femoral atherosclerotic plaques von Gude, Mette Faurholdt, Hjortebjerg, Rikke, Bjerre, Mette, Pedersen, Anne Kathrine Nissen, Oxvig, Claus, Rasmussen, Lars Melholt, Frystyk, Jan, Steffensen, Lasse

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HSP60 chaperone deficiency disrupts the mitochondrial matrix proteome and dysregulates cholesterol synthesis von Cömert, Cagla, Kjær-Sørensen, Kasper, Hansen, Jakob, Carlsen, Jasper, Just, Jesper, Meaney, Brandon F., Østergaard, Elsebet, Luo, Yonglun, Oxvig, Claus, Schmidt-Laursen, Lisbeth, Palmfeldt, Johan, Fernandez-Guerra, Paula, Bross, Peter

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Effect of pregnancy-associated plasma protein-A (PAPP-A) single-nucleotide polymorphisms on the level and activity of PAPP-A and the hormone profile in fluid from normal human smal... von Bøtkjær, Jane Alrø, M.Sc, Borgbo, Tanni, Ph.D, Kløverpris, Søren, Ph.D, Noer, Pernille Rimmer, M.Sc, Oxvig, Claus, Ph.D, Andersen, Claus Yding, D.M.Sc

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Lactation opposes pappalysin‐1‐driven pregnancy‐associated breast cancer von Takabatake, Yukie, Oxvig, Claus, Nagi, Chandandeep, Adelson, Kerin, Jaffer, Shabnam, Schmidt, Hank, Keely, Patricia J, Eliceiri, Kevin W, Mandeli, John, Germain, Doris

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