On becoming more complex (and what to do about it) von Owen Jacobs, Thomas

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On becoming more complex and what to do about it

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A guide to the strategic leader development inventory

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AB5075, a Highly Virulent Isolate of Acinetobacter baumannii, as a Model Strain for the Evaluation of Pathogenesis and Antimicrobial Treatments von Jacobs, Anna C, Thompson, Mitchell G, Black, Chad C, Kessler, Jennifer L, Clark, Lily P, McQueary, Christin N, Gancz, Hanan Y, Corey, Brendan W, Moon, Jay K, Si, Yuanzheng, Owen, Matthew T, Hallock, Justin D, Kwak, Yoon I, Summers, Amy, Li, Charles Z, Rasko, David A, Penwell, William F, Honnold, Cary L, Wise, Matthew C, Waterman, Paige E, Lesho, Emil P, Stewart, Rena L, Actis, Luis A, Palys, Thomas J, Craft, David W, Zurawski, Daniel V

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LD Score regression distinguishes confounding from polygenicity in genome-wide association studies von Bulik-Sullivan, Brendan K, Loh, Po-Ru, Finucane, Hilary K, Ripke, Stephan, Yang, Jian, Patterson, Nick, Daly, Mark J, Price, Alkes L, Neale, Benjamin M

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Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study von Khoo, Saye H, Fitzgerald, Richard, Fletcher, Thomas, Ewings, Sean, Jaki, Thomas, Lyon, Rebecca, Downs, Nichola, Walker, Lauren, Tansley-Hancock, Olana, Greenhalf, William, Woods, Christie, Reynolds, Helen, Marwood, Ellice, Mozgunov, Pavel, Adams, Emily, Bullock, Katie, Holman, Wayne, Bula, Marcin D, Gibney, Jennifer L, Saunders, Geoffrey, Corkhill, Andrea, Hale, Colin, Thorne, Kerensa, Chiong, Justin, Condie, Susannah, Pertinez, Henry, Painter, Wendy, Wrixon, Emma, Johnson, Lucy, Yeats, Sara, Mallard, Kim, Radford, Mike, Fines, Keira, Shaw, Victoria, Owen, Andrew, Lalloo, David G, Jacobs, Michael, Griffiths, Gareth

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Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma von Carroll, Thomas M., Chadwick, Joseph A., Owen, Richard P., White, Michael J., Kaplinsky, Joseph, Peneva, Iliana, Frangou, Anna, Xie, Phil F., Chang, Jaeho, Roth, Andrew, Amess, Bob, James, Sabrina A., Rei, Margarida, Fuchs, Hannah S., McCann, Katy J., Omiyale, Ayo O., Jacobs, Brittany-Amber, Lord, Simon R., Norris-Bulpitt, Stewart, Dobbie, Sam T., Griffiths, Lucinda, Ramirez, Kristen Aufiero, Ricciardi, Toni, Macri, Mary J., Ryan, Aileen, Venhaus, Ralph R., Van den Eynde, Benoit J., Karydis, Ioannis, Schuster-Böckler, Benjamin, Middleton, Mark R., Lu, Xin, Ahern, David, Amess, Bob, Ramirez, Kristen Aufiero, Berridge, Georgina, Carroll, Thomas M., Chadwick, Joseph A., Chang, Jaeho, Cheng, Jingfei, Dobbie, Sam T., Drozdz, Magdalena, Fischer, Roman, Frangou, Anna, Fuchs, Hannah S., Griffiths, Lucinda, Inoue, Masato, Jacobs, Brittany-Amber, James, Sabrina A., Kaplinsky, Joseph, Karydis, Ioannis, Kessler, Benedikt M., Lord, Simon R., Lou, Hantao, Lu, Xin, Macri, Mary J., McCann, Katy J., McGregor, Naomi, Middleton, Mark R., Norris-Bulpitt, Stewart, Omiyale, Ayo O., Owen, Richard P., Peneva, Iliana, Phetsouphanh, Chansavath, Rei, Margarida, Ricciardi, Toni, Roth, Andrew, Puig, Carlos Ruiz, Ryan, Aileen, Schuster-Böckler, Benjamin, Siejka-Zielińska, Paulina, Song, Chunxiao, Tomkova, Marketa, Van den Eynde, Benoit J., Velikova, Gergana, Venhaus, Ralph R., White, Michael J., Xie, Phil F.

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The Efficacy of Blood Flow Restriction Training to Improve Quadriceps Muscle Function after ACL Reconstruction von Erickson, Lauren N, Owen, Meredith K, Casadonte, Kelsey R, Janatova, Tereza, Lucas, Kathryn, Spencer, Kylie, Brightwell, Benjamin D, Graham, Megan C, White, McKenzie, Thomas, Nicholas T, Latham, Christine M, Jacobs, Cale, Conley, Caitlin, Thompson, Kathryn L, Johnson, Darren L, Hardy, Peter, Fry, Christopher S, Noehren, Brian

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An Open Label, Adaptive, Phase 1 Trial of High‐Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS‐CoV‐2 von Walker, Lauren E., FitzGerald, Richard, Saunders, Geoffrey, Lyon, Rebecca, Fisher, Michael, Martin, Karen, Eberhart, Izabela, Woods, Christie, Ewings, Sean, Hale, Colin, Rajoli, Rajith K. R., Else, Laura, Dilly‐Penchala, Sujan, Amara, Alieu, Lalloo, David G., Jacobs, Michael, Pertinez, Henry, Hatchard, Parys, Waugh, Robert, Lawrence, Megan, Johnson, Lucy, Fines, Keira, Reynolds, Helen, Rowland, Timothy, Crook, Rebecca, Okenyi, Emmanuel, Byrne, Kelly, Mozgunov, Pavel, Jaki, Thomas, Khoo, Saye, Owen, Andrew, Griffiths, Gareth, Fletcher, Thomas E.

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Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia von Pardiñas, Antonio F, Smart, Sophie E, Willcocks, Isabella R, Holmans, Peter A, Dennison, Charlotte A, Lynham, Amy J, Legge, Sophie E, Baune, Bernhard T, Bigdeli, Tim B, Cairns, Murray J, Corvin, Aiden, Fanous, Ayman H, Frank, Josef, Kelly, Brian, McQuillin, Andrew, Melle, Ingrid, Mortensen, Preben B, Mowry, Bryan J, Pato, Carlos N, Periyasamy, Sathish, Rietschel, Marcella, Rujescu, Dan, Simonsen, Carmen, St Clair, David, Tooney, Paul, Wu, Jing Qin, Andreassen, Ole A, Kowalec, Kaarina, Sullivan, Patrick F, Murray, Robin M, Owen, Michael J, MacCabe, James H, O’Donovan, Michael C, Walters, James T. R, Ajnakina, Olesya, Alameda, Luis, Barnes, Thomas R. E, Berardi, Domenico, Bonora, Elena, Camporesi, Sara, Cleusix, Martine, Conus, Philippe, Crespo-Facorro, Benedicto, D’Andrea, Giuseppe, Demjaha, Arsime, Do, Kim Q, Doody, Gillian A, Eap, Chin B, Ferchiou, Aziz, Di Forti, Marta, Guidi, Lorenzo, Homman, Lina, Jenni, Raoul, Joyce, Eileen M, Kassoumeri, Laura, Khadimallah, Inès, Lastrina, Ornella, Muratori, Roberto, Noyan, Handan, O’Neill, Francis A, Pignon, Baptiste, Restellini, Romeo, Richard, Jean-Romain, Schürhoff, Franck, Španiel, Filip, Szöke, Andrei, Tarricone, Ilaria, Tortelli, Andrea, Üçok, Alp, Vázquez-Bourgon, Javier

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Riluzole does not ameliorate disease caused by cytoplasmic TDP‐43 in a mouse model of amyotrophic lateral sclerosis von Wright, Amanda L., Della Gatta, Paul A., Le, Sheng, Berning, Britt A., Mehta, Prachi, Jacobs, Kelly R., Gul, Hossai, San Gil, Rebecca, Hedl, Thomas J., Riddell, Winonah R., Watson, Owen, Keating, Sean S., Venturato, Juliana, Chung, Roger S., Atkin, Julie D., Lee, Albert, Shi, Bingyang, Blizzard, Catherine A., Morsch, Marco, Walker, Adam K.

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Sex Differences in Quadriceps Atrophy After Anterior Cruciate Ligament Tear von Owen, Meredith K, Casadonte, Kelsey R, Thomas, Nicholas T, Latham, Christine M, Brightwell, Camille R, Thompson, Katherine L, Hawk, Gregory S, Jacobs, Cale A, Johnson, Darren L, Fry, Christopher S, Noehren, Brian

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Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled, double-blind, phase 2... von Khoo, Saye H, FitzGerald, Richard, Saunders, Geoffrey, Middleton, Calley, Ahmad, Shazaad, Edwards, Christopher J, Hadjiyiannakis, Dennis, Walker, Lauren, Lyon, Rebecca, Shaw, Victoria, Mozgunov, Pavel, Periselneris, Jimstan, Woods, Christie, Bullock, Katie, Hale, Colin, Reynolds, Helen, Downs, Nichola, Ewings, Sean, Buadi, Amanda, Cameron, David, Edwards, Thomas, Knox, Emma, Donovan-Banfield, I'ah, Greenhalf, William, Chiong, Justin, Lavelle-Langham, Lara, Jacobs, Michael, Northey, Josh, Painter, Wendy, Holman, Wayne, Lalloo, David G, Tetlow, Michelle, Hiscox, Julian A, Jaki, Thomas, Fletcher, Thomas, Griffiths, Gareth, Paton, Nicholas, Hayden, Fred, Darbyshire, Janet, Lucas, Amy, Lorch, Ulrika, Freedman, Andrew, Knight, Richard, Julious, Stevan, Byrne, Rachel, Cubas Atienzar, Ana, Jones, Jayne, Williams, Chris, Song, Anna, Dixon, Jan, Alexandersson, Anja, Hatchard, Parys, Tilt, Emma, Titman, Andrew, Doce Carracedo, Ale, Chandran Gorner, Vatsi, Davies, Andrea, Woodhouse, Louis, Carlucci, Nicola, Okenyi, Emmanuel, Bula, Marcin, Dodd, Kate, Gibney, Jennifer, Dry, Lesley, Rashid Gardner, Zalina, Sammour, Amin, Cole, Christine, Rowland, Tim, Tsakiroglu, Maria, Yip, Vincent, Osanlou, Rostam, Stewart, Anna, Parker, Ben, Turgut, Tolga, Ahmed, Afshan, Starkey, Kay, Subin, Sujamole, Stockdale, Jennifer, Herring, Lisa, Baker, Jonathon, Oliver, Abigail, Pacurar, Mihaela, Owens, Dan, Munro, Alistair, Babbage, Gavin, Faust, Saul, Harvey, Matthew, Pratt, Danny, Nagra, Deepak, Vyas, Aashish

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Comparison of switching to 6-week dosing of natalizumab versus continuing with 4-week dosing in patients with relapsing-remitting multiple sclerosis (NOVA): a randomised, controlle... von Foley, John F, Defer, Gilles, Ryerson, Lana Zhovtis, Cohen, Jeffrey A, Arnold, Douglas L, Butzkueven, Helmut, Cutter, Gary, Giovannoni, Gavin, Killestein, Joep, Wiendl, Heinz, Smirnakis, Karen, Xiao, Shan, Kong, George, Kuhelj, Robert, Campbell, Nolan, van der Walt, Anneke, Dwyer, Christopher, Buzzard, Katherine, Spies, Judith, Parratt, John, van Pesch, Vincent, Willekens, Barbara, Perrotta, Gaetano, Bartholomé, Emmanuel, Grand'Maison, Francois, Jacques, Francois, Giacomini, Paul, Vosoughi, Reza, Girard, Jean-Marc, de Seze, Jerome, Lebrun Frenay, Christine, Ruet, Aurelie, Laplaud, David-Axel, Reifschneider, Gerd, Wagner, Bert, Rauer, Sebastian, Pul, Refik, Seipelt, Maria, Berthele, Achim, Klotz, Luisa, Kallmann, Boris-Alexander, Paul, Friedemann, Achiron, Anat, Lus, Giacomo, Centonze, Diego, Patti, Francesco, Grimaldi, Luigi, Hupperts, Raymond, Frequin, Stephan, Fermont, Jiske, Madueno, Sara Eichau, Alonso Torres, Ana Maria, Costa-Frossard França, Lucienne, Meca-Lallana, Jose Eustasio, Ruiz, Luis Brieva, Pearson, Owen, Rog, David, Evangelou, Nikolaos, Ismail, Azza, Lathi, Ellen, Fox, Edward, Leist, Thomas, Sloane, Jacob, Wu, Gregory, Khatri, Bhupendra, Steingo, Brian, Thrower, Ben, Gudesblatt, Mark, Calkwood, Jonathan, Bandari, Daniel, Scagnelli, John, Laganke, Christopher, Robertson, Derrick, Kipp, Lucas, Belkin, Martin, Cohan, Stanley, Goldstick, Lawrence, Courtney, Ardith, Vargas, Wendy, Sylvester, Andrew, Srinivasan, Jayshri, Kannan, Meena, Picone, Maryann, English, Jeffrey, Napoli, Salvatore, Balabanov, Roumen, Zaydan, Islam, Nicholas, Jacqueline, Kaplan, Jeffrey, Lublin, Fred, Riser, Emily, Miller, Tamara, Alvarez, Enrique, Wray, Sibyl, Gross, Jeffrey, Pawate, Siddharama, Hersh, Carrie, McCarthy, Lucas, Crayton, Heidi, Graves, Jennifer

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AGILE: a seamless phase I/IIa platform for the rapid evaluation of candidates for COVID-19 treatment: an update to the structured summary of a study protocol for a randomised platf... von Griffiths, Gareth O, FitzGerald, Richard, Jaki, Thomas, Corkhill, Andrea, Reynolds, Helen, Ewings, Sean, Condie, Susannah, Tilt, Emma, Johnson, Lucy, Radford, Mike, Simpson, Catherine, Saunders, Geoffrey, Yeats, Sara, Mozgunov, Pavel, Tansley-Hancock, Olana, Martin, Karen, Downs, Nichola, Eberhart, Izabela, Martin, Jonathan W B, Goncalves, Cristiana, Song, Anna, Fletcher, Tom, Byrne, Kelly, Lalloo, David G, Owen, Andrew, Jacobs, Michael, Walker, Lauren, Lyon, Rebecca, Woods, Christie, Gibney, Jennifer, Chiong, Justin, Chandiwana, Nomathemba, Jacob, Shevin, Lamorde, Mohammed, Orrell, Catherine, Pirmohamed, Munir, Khoo, Saye

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Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis: The BLING III Randomized Clinical Trial von Dulhunty, Joel M, Brett, Stephen J, De Waele, Jan J, Rajbhandari, Dorrilyn, Billot, Laurent, Cotta, Menino O, Davis, Joshua S, Finfer, Simon, Hammond, Naomi E, Knowles, Serena, Liu, Xiaoqiu, McGuinness, Shay, Mysore, Jayanthi, Paterson, David L, Peake, Sandra, Rhodes, Andrew, Roberts, Jason A, Roger, Claire, Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Myburgh, John A, Lipman, Jeffrey

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Zone 1 Endovascular Balloon Occlusion of the Aorta vs Resuscitative Thoracotomy for Patient Resuscitation After Severe Hemorrhagic Shock von Cralley, Alexis L, Vigneshwar, Navin, Moore, Ernest E, Dubose, Joseph, Brenner, Megan L, Sauaia, Angela

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PEMapper and PECaller provide a simplified approach to whole-genome sequencing von Johnston, H. Richard, Chopra, Pankaj, Wingo, Thomas S., Patel, Viren, Epstein, Michael P., Mulle, Jennifer G., Warren, Stephen T., Zwick, Michael E., Cutler, David J.

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Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis von Derks, Eske M, Vorstman, Jacob A S, Ripke, Stephan, Kahn, Rene S, Ophoff, Roel A

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GDF8 inhibition enhances musculoskeletal recovery and mitigates posttraumatic osteoarthritis following joint injury von Brightwell, Camille R, Latham, Christine M, Keeble, Alexander R, Thomas, Nicholas T, Owen, Allison M, Reeves, Kelsey A, Long, Douglas E, Patrick, Matthew, Gonzalez-Velez, Sara, Abed, Varag, Annamalai, Ramkumar T, Jacobs, Cale, Conley, Caitlin E, Hawk, Gregory S, Stone, Austin V, Fry, Jean L, Thompson, Katherine L, Johnson, Darren L, Noehren, Brian, Fry, Christopher S

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