The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits von Witkin, J.M., Monn, J.A., Schoepp, D.D., Li, X., Overshiner, C., Mitchell, S.N., Carter, G., Johnson, B., Rasmussen, K., Rorick-Kehn, L.M.

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M1 and m2 muscarinic receptor subtypes regulate antidepressant-like effects of the rapidly acting antidepressant scopolamine von Witkin, J M, Overshiner, C, Li, X, Catlow, J T, Wishart, G N, Schober, D A, Heinz, B A, Nikolayev, A, Tolstikov, V V, Anderson, W H, Higgs, R E, Kuo, M-S, Felder, C C

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Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N -Methyl-d-Aspartate Receptor Antago... von Witkin, J M, Mitchell, S N, Wafford, K A, Carter, G, Gilmour, G, Li, J, Eastwood, B J, Overshiner, C, Li, X, Rorick-Kehn, L, Rasmussen, K, Anderson, W H, Nikolayev, A, Tolstikov, V V, Kuo, M-S, Catlow, J T, Li, R, Smith, S C, Mitch, C H, Ornstein, P L, Swanson, S, Monn, J A

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In vivo occupancy of dopamine D3 receptors by antagonists produces neurochemical and behavioral effects of potential relevance to attention-deficit-hyperactivity disorder von Barth, V, Need, A B, Tzavara, E T, Giros, B, Overshiner, C, Gleason, S D, Wade, M, Johansson, A M, Perry, K, Nomikos, G G, Witkin, J M

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Procholinergic and memory enhancing properties of the selective norepinephrine uptake inhibitor atomoxetine von Tzavara, E T, Bymaster, F P, Overshiner, C D, Davis, R J, Perry, K W, Wolff, M, McKinzie, D L, Witkin, J M, Nomikos, G G

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M 1 and M 2 Muscarinic Receptor Subtypes Regulate Antidepressant-Like Effects of the Rapidly Acting Antidepressant Scopolamine von Witkin, J. M., Overshiner, C., Li, X., Catlow, J. T., Wishart, G. N., Schober, D. A., Heinz, B. A., Nikolayev, A., Tolstikov, V. V., Anderson, W. H., Higgs, R. E., Kuo, M.-S., Felder, C. C.

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In Vivo Occupancy of Dopamine D 3 Receptors by Antagonists Produces Neurochemical and Behavioral Effects of Potential Relevance to Attention-Deficit–Hyperactivity Disorder von Barth, V., Need, A. B., Tzavara, E. T., Giros, B., Overshiner, C., Gleason, S. D., Wade, M., Johansson, A. M., Perry, K., Nomikos, G. G., Witkin, J. M.

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Disinhibitory effects of LY354740, a new mGluR2 agonist, on behaviors suppressed by electric shock in rats and pigeons von Benvenga, Mark J., Overshiner, Carl D., Monn, James A., Leander, J. David

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Pharmacological profile of LY301317, a potent and selective 5-HT1A agonist von Wolff, Mary C., Benvenga, Mark J., Calligaro, David O., Fuller, Ray W., Gidda, Jaswant S., Hemrick-Luecke, Susan, Lucot, James B., Nelson, David L., Overshiner, Carl D., Leander, J. David

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Disinhibitory effects of LY354740, a new mGluR2 agonist, on behaviors suppressed by electric shock, in rats and pigeons von Benvenga, MJ, Overshiner, CD, Monn, JA, Leander, JD

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N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential a... von Fell, Matthew J, Witkin, Jeffrey M, Falcone, Julie F, Katner, Jason S, Perry, Kenneth W, Hart, John, Rorick-Kehn, Linda, Overshiner, Carl D, Rasmussen, Kurt, Chaney, Stephen F, Benvenga, Mark J, Li, Xia, Marlow, Deanna L, Thompson, Linda K, Luecke, Susan K, Wafford, Keith A, Seidel, Wesley F, Edgar, Dale M, Quets, Anne T, Felder, Christian C, Wang, XuShan, Heinz, Beverly A, Nikolayev, Alexander, Kuo, Ming-Shang, Mayhugh, Daniel, Khilevich, Albert, Zhang, Deyi, Ebert, Philip J, Eckstein, James A, Ackermann, Bradley L, Swanson, Steven P, Catlow, John T, Dean, Robert A, Jackson, Kimberley, Tauscher-Wisniewski, Sitra, Marek, Gerard J, Schkeryantz, Jeffrey M, Svensson, Kjell A

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Novel bicyclo[3.1.0]hexane analogs as antagonists of metabotropic glutamate 2/3 receptors for the treatment of depression von Dressman, Bruce A., Tromiczak, Eric G., Chappell, Mark D., Tripp, Allie E., Quimby, Steven J., Vetman, Tatiana, Fivush, Adam M., Matt, James, Jaramillo, Carlos, Li, Renhua, Khilevich, Albert, Blanco, Maria-Jesus, Smith, Stephon C., Carpintero, Mercedes, de Diego, José Eugenio, Barberis, Mario, García-Cerrada, Susana, Soriano, José F., Schkeryantz, Jeffrey M., Witkin, Jeffrey M., Wafford, Keith A., Seidel, Wesley, Britton, Thomas, Overshiner, Carl D., Li, Xia, Wang, Xu-Shan, Heinz, Beverly A., Catlow, John T., Swanson, Steven, Bedwell, David, Ornstein, Paul L., Mitch, Charles H.

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Discovery of (1S,2R,3S,4S,5R,6R)‑2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371·HCl): A Potent, Metabo... von Chappell, Mark D, Li, Renhua, Smith, Stephon C, Dressman, Bruce A, Tromiczak, Eric G, Tripp, Allie E, Blanco, Maria-Jesus, Vetman, Tatiana, Quimby, Steven J, Matt, James, Britton, Thomas C, Fivush, Adam M, Schkeryantz, Jeffrey M, Mayhugh, Daniel, Erickson, Jon A, Bures, Mark G, Jaramillo, Carlos, Carpintero, Mercedes, Diego, José Eugenio de, Barberis, Mario, Garcia-Cerrada, Susana, Soriano, José F, Antonysamy, Stephen, Atwell, Shane, MacEwan, Iain, Condon, Bradley, Sougias, Christine, Wang, Jing, Zhang, Aiping, Conners, Kris, Groshong, Chris, Wasserman, Stephen R, Koss, John W, Witkin, Jeffrey M, Li, Xia, Overshiner, Carl, Wafford, Keith A, Seidel, Wesley, Wang, Xu-Shan, Heinz, Beverly A, Swanson, Steven, Catlow, John T, Bedwell, David W, Monn, James A, Mitch, Charles H, Ornstein, Paul L

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N -(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1 H -imidazole-4-carboxamide (THIIC), a Novel Metabotropic Glutamate 2 Potentiator with Potentia... von Fell, Matthew J., Witkin, Jeffrey M., Falcone, Julie F., Katner, Jason S., Perry, Kenneth W., Hart, John, Rorick-Kehn, Linda, Overshiner, Carl D., Rasmussen, Kurt, Chaney, Stephen F., Benvenga, Mark J., Li, Xia, Marlow, Deanna L., Thompson, Linda K., Luecke, Susan K., Wafford, Keith A., Seidel, Wesley F., Edgar, Dale M., Quets, Anne T., Felder, Christian C., Wang, XuShan, Heinz, Beverly A., Nikolayev, Alexander, Kuo, Ming-Shang, Mayhugh, Daniel, Khilevich, Albert, Zhang, Deyi, Ebert, Philip J., Eckstein, James A., Ackermann, Bradley L., Swanson, Steven P., Catlow, John T., Dean, Robert A., Jackson, Kimberley, Tauscher-Wisniewski, Sitra, Marek, Gerard J., Schkeryantz, Jeffrey M., Svensson, Kjell A.

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